| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bankole A Johnso. Role of the serotonergic system in the neurobiology of alcoholism: implications for treatment. CNS drugs. vol 18. issue 15. 2005-01-24. PMID:15581381. |
these studies have demonstrated the important role of serotonin pathways, particularly as they relate to dopaminergic function, which mediates alcohol-induced reward associated with its abuse liability. |
2005-01-24 |
2023-08-12 |
Not clear |
| Satoshi Ikemoto, Roy A Wis. Mapping of chemical trigger zones for reward. Neuropharmacology. vol 47 Suppl 1. 2004-12-20. PMID:15464137. |
this approach has identified gabaergic, dopaminergic, glutamatergic, and cholinergic trigger zones within meso-corticolimbic circuitry important for natural reward function. |
2004-12-20 |
2023-08-12 |
Not clear |
| Geraldine Rogers, Peter Joyce, Roger Mulder, Douglas Sellman, Allison Miller, Melanie Allington, Robin Olds, Elisabeth Wells, Martin Kenned. Association of a duplicated repeat polymorphism in the 5'-untranslated region of the DRD4 gene with novelty seeking. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 126B. issue 1. 2004-10-19. PMID:15048656. |
dopaminergic genes have been prime candidates in the search for the genetic factors underlying ns because of the central role that dopamine plays in the brain's reward system. |
2004-10-19 |
2023-08-12 |
human |
| Claire Matson Cannon, Mustafa R Bseikr. Is dopamine required for natural reward? Physiology & behavior. vol 81. issue 5. 2004-10-18. PMID:15234179. |
dopamine systems are activated in animals drinking sugar solutions, and lesions of dopaminergic neurons or pharmacological blockade of da receptors seem to reduce the reward value of both sweet tastes and drugs of abuse. |
2004-10-18 |
2023-08-12 |
mouse |
| V Riban, A Pereira de Vasconcelos, B T Phâm-Lê, A Ferrandon, C Marescaux, A Nehlig, A Depauli. Modifications of local cerebral glucose utilization in thalamic structures following injection of a dopaminergic agonist in the nucleus accumbens--involvement in antiepileptic effects? Experimental neurology. vol 188. issue 2. 2004-08-10. PMID:15246844. |
dopaminergic transmission in the nucleus accumbens (nacc) is implicated in different aspects of reward and motivational mechanisms. |
2004-08-10 |
2023-08-12 |
rat |
| Benjamin Gauter, Roman Rukwied, Christoph Konra. Cannabinoid agonists in the treatment of blepharospasm--a case report study. Neuro endocrinology letters. vol 25. issue 1-2. 2004-08-03. PMID:15159681. |
in the brain a dense co-localisation of cannabinoid (cb1) and dopamine (d2)-receptor was identified which had been associated with the influence of cannabinoids on the dopaminergic reward system. |
2004-08-03 |
2023-08-12 |
Not clear |
| Huibert D Mansvelder, Mischa De Rover, Daniel S McGehee, Arjen B Brussaar. Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623355. |
cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. |
2004-07-22 |
2023-08-12 |
Not clear |
| Huibert D Mansvelder, Mischa De Rover, Daniel S McGehee, Arjen B Brussaar. Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623355. |
nicotine reinforces smoking behaviour by activating nicotinic acetylcholine receptors in the midbrain dopaminergic reward centres. |
2004-07-22 |
2023-08-12 |
Not clear |
| Joshua W Brown, Daniel Bullock, Stephen Grossber. How laminar frontal cortex and basal ganglia circuits interact to control planned and reactive saccades. Neural networks : the official journal of the International Neural Network Society. vol 17. issue 4. 2004-07-06. PMID:15109680. |
model simulations show how dopaminergic reward and non-reward signals guide monkeys to learn and perform saccadic eye movements in the fixation, single saccade, overlap, gap, and delay (memory-guided) saccade tasks. |
2004-07-06 |
2023-08-12 |
monkey |
| Roney Welinton Dias de Oliveira, Ester Miyuki Nakamura-Palacio. Haloperidol increases the disruptive effect of alcohol on spatial working memory in rats: a dopaminergic modulation in the medial prefrontal cortex. Psychopharmacology. vol 170. issue 1. 2004-05-17. PMID:12783154. |
the medial portion of the pfc (mpfc) is also part of a "brain reward circuit" as constituted by the mesocorticolimbic dopaminergic system. |
2004-05-17 |
2023-08-12 |
rat |
| Manabu Shinohara, Hiroko Mizushima, Masami Hirano, Kunihiko Shioe, Mie Nakazawa, Yoshimitsu Hiejima, Yutaka Ono, Shigenobu Kanb. Eating disorders with binge-eating behaviour are associated with the s allele of the 3'-UTR VNTR polymorphism of the dopamine transporter gene. Journal of psychiatry & neuroscience : JPN. vol 29. issue 2. 2004-05-17. PMID:15069467. |
the dopaminergic system is associated with feelings of pleasure and reward and with positive hedonic processes related to food, sexual activity and certain substances. |
2004-05-17 |
2023-08-12 |
Not clear |
| Esther L Yue, Thomas A Cleland, Michelle Pavlis, Christiane Linste. Opposing effects of D1 and D2 receptor activation on odor discrimination learning. Behavioral neuroscience. vol 118. issue 1. 2004-04-13. PMID:14979796. |
dopaminergic modulation of cortical activity has been implicated in the formation of reward associations. |
2004-04-13 |
2023-08-12 |
rat |
| Steven R Laviolette, Roger A Gallegos, Steven J Henriksen, Derek van der Koo. Opiate state controls bi-directional reward signaling via GABAA receptors in the ventral tegmental area. Nature neuroscience. vol 7. issue 2. 2004-04-02. PMID:14730310. |
here we show that a discrete population of gaba(a) receptors in the mammalian ventral tegmental area (vta) serves as a potential addiction switching mechanism by gating reward transmission through one of two neural motivational systems: either a dopamine-independent (opiate-naive) or a dopaminergic (opiate-dependent or opiate-withdrawn) system. |
2004-04-02 |
2023-08-12 |
rat |
| F Melis, A Crisafulli, A Rocchitta, F Tocco, A Conc. Does reduction of blood prolactin levels reveal the activation of central dopaminergic pathways conveying reward in top athletes? Medical hypotheses. vol 61. issue 1. 2004-03-10. PMID:12781656. |
does reduction of blood prolactin levels reveal the activation of central dopaminergic pathways conveying reward in top athletes? |
2004-03-10 |
2023-08-12 |
human |
| Laure Buydens-Branchey, Marc Branchey, Dana L McMakin, Joseph R Hibbel. Polyunsaturated fatty acid status and relapse vulnerability in cocaine addicts. Psychiatry research. vol 120. issue 1. 2004-03-08. PMID:14500111. |
there is also evidence derived mostly from the animal literature that pufas could play a role in the abuse of substances through their action on central serotonergic and dopaminergic systems that are both known to play a role in reward mechanisms. |
2004-03-08 |
2023-08-12 |
human |
| G Juckel, L Sass, A Hein. Anhedonia, self-experience in schizophrenia, and implications for treatment. Pharmacopsychiatry. vol 36 Suppl 3. 2004-02-27. PMID:14677076. |
concerning treatment of anhedonia, it was often hypothesized that anhedonia is associated with a dysfunction of the mesolimbic dopaminergic reward system. |
2004-02-27 |
2023-08-12 |
Not clear |
| A Heinz, M Schäfer, J D Higley, J H Krystal, D Goldma. Neurobiological correlates of the disposition and maintenance of alcoholism. Pharmacopsychiatry. vol 36 Suppl 3. 2004-02-27. PMID:14677088. |
sensitization of the dopaminergic and opioidergic reward system may contribute to alcohol craving and reduced control of alcohol intake. |
2004-02-27 |
2023-08-12 |
Not clear |
| M Keitz, C Martin-Soelch, K L Leender. Reward processing in the brain: a prerequisite for movement preparation? Neural plasticity. vol 10. issue 1-2. 2004-02-18. PMID:14640313. |
in this review, we define some of the concepts associated with reward, summarize the crucial importance of the dopaminergic system, and discuss the currently available neuroimaging studies in man. |
2004-02-18 |
2023-08-12 |
human |
| Eliyahu Dremencov, Iris Gispan-Herman, Merav Rosenstein, Avivit Mendelman, David H Overstreet, Joseph Zohar, Gal Yadi. The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 1. 2004-02-18. PMID:14687868. |
because of the central role of accumbal dopamine in the mediation of motivation and reward, our measurements were focused on dopaminergic neurotransmission in the nucleus accumbens (nac). |
2004-02-18 |
2023-08-12 |
rat |
| Monika Johann, Rainer Wiegand, Alexander Kharraz, Gabriela Bobbe, Gabriele Sommer, Göran Hajak, Norbert Wodarz, Peter Eichhamme. [Transcranial magnetic stimulation for nicotine dependence]. Psychiatrische Praxis. vol 30 Suppl 2. 2004-02-17. PMID:14509058. |
in animal experiments, repetitive transcranial magnetic stimulation (rtms) exhibited modulatory effects on dopaminergic neurotransmission in regions of the so-called reward system. |
2004-02-17 |
2023-08-12 |
Not clear |