| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming Xu, Jianhua Zhan. Molecular genetic probing of dopamine receptors in drug addiction. Current opinion in drug discovery & development. vol 7. issue 5. 2006-04-19. PMID:15503872. |
the dopaminergic system of the brain plays a central role in natural reward and motivation and is the main neural substrate for the actions of abusive drugs. |
2006-04-19 |
2023-08-12 |
mouse |
| Kelly A Foley, Melissa A Fudge, Martin Kavaliers, Klaus-Peter Ossenkop. Quinpirole-induced behavioral sensitization is enhanced by prior scheduled exposure to sucrose: A multi-variable examination of locomotor activity. Behavioural brain research. vol 167. issue 1. 2006-04-12. PMID:16198008. |
sensitization of dopaminergic neural reward circuits has been hypothesized to be involved in the development of drug addiction. |
2006-04-12 |
2023-08-12 |
rat |
| D Mueller, C A Chapman, J Stewar. Amphetamine induces dendritic growth in ventral tegmental area dopaminergic neurons in vivo via basic fibroblast growth factor. Neuroscience. vol 137. issue 3. 2006-04-12. PMID:16338078. |
dopaminergic neurons of the ventral tegmental area are implicated in the physiology of reward, and long-lasting changes in their function induced by exposure to psychostimulant drugs are related to the pathophysiology of drug abuse. |
2006-04-12 |
2023-08-12 |
rat |
| Barbara Ziolkowska, Agnieszka Gieryk, Wiktor Bilecki, Agnieszka Wawrzczak-Bargiela, Krzysztof Wedzony, Agnieszka Chocyk, Patria E Danielson, Elizabeth A Thomas, Brian S Hilbush, J Gregor Sutcliffe, Ryszard Przewlock. Regulation of alpha-synuclein expression in limbic and motor brain regions of morphine-treated mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 20. 2006-03-23. PMID:15901780. |
chronic exposure to opiates produces dependence and addiction, which may result from neuroadaptations in the dopaminergic reward pathway and its target brain regions. |
2006-03-23 |
2023-08-12 |
mouse |
| Kelly K Anderson, David A Ballok, Neena Prasad, Henry Szechtman, Boris Saki. Impaired response to amphetamine and neuronal degeneration in the nucleus accumbens of autoimmune MRL-lpr mice. Behavioural brain research. vol 166. issue 1. 2006-03-14. PMID:16183144. |
based on the stimulatory effects of d-amphetamine sulfate (amph) on sucrose intake, the present study pharmacologically probes the functional status of central dopaminergic circuits involved in control of behavioral reward. |
2006-03-14 |
2023-08-12 |
mouse |
| Amy M Naleid, Martha K Grace, David E Cummings, Allen S Levin. Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides. vol 26. issue 11. 2006-03-09. PMID:16137788. |
one of these is the ventral tegmental area (vta), a primary node of the mesolimbic reward pathway, which sends dopaminergic projections to the nucleus accumbens (acb), among other sites. |
2006-03-09 |
2023-08-12 |
rat |
| Helen Fisher, Arthur Aron, Lucy L Brow. Romantic love: an fMRI study of a neural mechanism for mate choice. The Journal of comparative neurology. vol 493. issue 1. 2006-03-09. PMID:16255001. |
yet mammals and birds express mate preferences and make mate choices, and data suggest that this "attraction system" is associated with the dopaminergic reward system. |
2006-03-09 |
2023-08-12 |
Not clear |
| Helen Fisher, Arthur Aron, Lucy L Brow. Romantic love: an fMRI study of a neural mechanism for mate choice. The Journal of comparative neurology. vol 493. issue 1. 2006-03-09. PMID:16255001. |
these and other results suggest that dopaminergic reward pathways contribute to the "general arousal" component of romantic love; romantic love is primarily a motivation system, rather than an emotion; this drive is distinct from the sex drive; romantic love changes across time; and romantic love shares biobehavioral similarities with mammalian attraction. |
2006-03-09 |
2023-08-12 |
Not clear |
| Okihide Hikosaka, Kae Nakamura, Hiroyuki Nakahar. Basal ganglia orient eyes to reward. Journal of neurophysiology. vol 95. issue 2. 2006-02-28. PMID:16424448. |
it is suggested that the reward modulation occurs in the caudate where cortical inputs carrying spatial signals and dopaminergic inputs carrying reward-related signals are integrated. |
2006-02-28 |
2023-08-12 |
Not clear |
| Valerie G Olson, Cyrus P Zabetian, Carlos A Bolanos, Scott Edwards, Michel Barrot, Amelia J Eisch, Thomas Hughes, David W Self, Rachael L Neve, Eric J Nestle. Regulation of drug reward by cAMP response element-binding protein: evidence for two functionally distinct subregions of the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 23. 2006-02-17. PMID:15944383. |
we identified vta subregion-specific differences in the proportion of dopaminergic and gabaergic neurons and in the dopaminergic projections to the nucleus accumbens, another brain region implicated in drug reward, and suggest that this may contribute to behavioral differences in this study. |
2006-02-17 |
2023-08-12 |
Not clear |
| Michael X Cohen, Jennifer Young, Jong-Min Baek, Christopher Kessler, Charan Ranganat. Individual differences in extraversion and dopamine genetics predict neural reward responses. Brain research. Cognitive brain research. vol 25. issue 3. 2006-02-15. PMID:16289773. |
psychologists have linked the personality trait extraversion both to differences in reward sensitivity and to dopamine functioning, but little is known about how these differences are reflected in the functioning of the brain's dopaminergic neural reward system. |
2006-02-15 |
2023-08-12 |
human |
| J Reid Meloy, Helen Fishe. Some thoughts on the neurobiology of stalking. Journal of forensic sciences. vol 50. issue 6. 2006-02-07. PMID:16382848. |
the authors discuss data from neuroimaging (fmri) studies of romantic love which suggest that these forms of stalking may be associated with heightened activity of subcortical dopaminergic pathways of the "reward system" of the brain, perhaps in combination with low activity of central serotonin. |
2006-02-07 |
2023-08-12 |
Not clear |
| Peter R Kufahl, Zhu Li, Robert C Risinger, Charles J Rainey, Gaohong Wu, Alan S Bloom, Shi-Jiang L. Neural responses to acute cocaine administration in the human brain detected by fMRI. NeuroImage. vol 28. issue 4. 2006-01-20. PMID:16061398. |
it is suggested that the dopaminergic pathways and the hierarchical brain networks may participate in mediating cocaine reward processes, associative learning, motivation, and memory in cocaine addiction in the human brain. |
2006-01-20 |
2023-08-12 |
human |
| Johannes Siegrist, Ingo Menrath, Tony Stöcker, Martina Klein, Thilo Kellermann, N Jon Shah, Karl Zilles, Frank Schneide. Differential brain activation according to chronic social reward frustration. Neuroreport. vol 16. issue 17. 2006-01-13. PMID:16272875. |
in line with prediction error theory, omission of an expected reward is associated with relative decreases of cerebral activation in dopaminergic brain areas. |
2006-01-13 |
2023-08-12 |
Not clear |
| Sae Unoki, Yukihisa Matsumoto, Makoto Mizunam. Participation of octopaminergic reward system and dopaminergic punishment system in insect olfactory learning revealed by pharmacological study. The European journal of neuroscience. vol 22. issue 6. 2006-01-10. PMID:16190895. |
participation of octopaminergic reward system and dopaminergic punishment system in insect olfactory learning revealed by pharmacological study. |
2006-01-10 |
2023-08-12 |
drosophila_melanogaster |
| Sae Unoki, Yukihisa Matsumoto, Makoto Mizunam. Participation of octopaminergic reward system and dopaminergic punishment system in insect olfactory learning revealed by pharmacological study. The European journal of neuroscience. vol 22. issue 6. 2006-01-10. PMID:16190895. |
this finding, combined with findings in previous studies, suggests that the octopaminergic reward system and dopaminergic punishment system participate in insect olfactory learning with various appetitive and aversive reinforcements. |
2006-01-10 |
2023-08-12 |
drosophila_melanogaster |
| Naoyuki Osaka, Mariko Osak. Striatal reward areas activated by implicit laughter induced by mimic words in humans: a functional magnetic resonance imaging study. Neuroreport. vol 16. issue 15. 2005-12-01. PMID:16189466. |
we tested a specific hypothesis that implicit laughter modulates the striatal dopaminergic reward centers by image formation of onomatopoeic words implying laughter and successfully confirmed the hypothesis. |
2005-12-01 |
2023-08-12 |
Not clear |
| Ingmar H A Franken, Peter Muri. Individual differences in reward sensitivity are related to food craving and relative body weight in healthy women. Appetite. vol 45. issue 2. 2005-11-29. PMID:15949869. |
these findings are discussed in the context of the involvement of dopaminergic reward circuitry in overeating. |
2005-11-29 |
2023-08-12 |
human |
| b' Esa Meririnne, Miina Kajos, Aino Kankaanp\\xc3\\xa4\\xc3\\xa4, Meri Koistinen, Kalervo Kiianmaa, Timo Sepp\\xc3\\xa4l\\xc3\\xa. Rewarding properties of the stereoisomers of 4-methylaminorex: involvement of the dopamine system. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:15982727.' |
furthermore, the involvement of the brain dopaminergic system in the 4-methylaminorex reward was tested with the dopamine d1- and d2-receptor antagonists sch 23390 and raclopride administered systemically, or with the neurotoxin 6-hydroxydopamine injected into the nucleus accumbens. |
2005-11-28 |
2023-08-12 |
rat |
| Lescia K Tremblay, Claudio A Naranjo, Simon J Graham, Nathan Herrmann, Helen S Mayberg, Stephanie Hevenor, Usoa E Bust. Functional neuroanatomical substrates of altered reward processing in major depressive disorder revealed by a dopaminergic probe. Archives of general psychiatry. vol 62. issue 11. 2005-11-28. PMID:16275810. |
functional neuroanatomical substrates of altered reward processing in major depressive disorder revealed by a dopaminergic probe. |
2005-11-28 |
2023-08-12 |
Not clear |