| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kendal-Reed, J C Walker, W T Morga. Investigating sources of response variability and neural mediation in human nasal irritation. Indoor air. vol 11. issue 3. 2001-09-20. PMID:11521503. |
due to an assumption that ni is mediated solely by the activation of the trigeminal (fifth cranial) nerve, much of the small amount of available information has been obtained from anosmic individuals, who lack olfactory (first cranial) nerve input to the brain and, thus, only have nasal trigeminal input remaining. |
2001-09-20 |
2023-08-12 |
human |
| A J Wiethoff, J R Harkema, A P Koretsky, W E Brow. Identification of mucosal injury in the murine nasal airways by magnetic resonance imaging: site-specific lesions induced by 3-methylindole. Toxicology and applied pharmacology. vol 175. issue 1. 2001-09-06. PMID:11509028. |
3-methylindole (3-mi) was chosen as a model nasal toxicant because systemic administration of this compound in mice results in a well-characterized necrotizing nasal lesion that is restricted to the olfactory mucosa. |
2001-09-06 |
2023-08-12 |
mouse |
| A J Wiethoff, J R Harkema, A P Koretsky, W E Brow. Identification of mucosal injury in the murine nasal airways by magnetic resonance imaging: site-specific lesions induced by 3-methylindole. Toxicology and applied pharmacology. vol 175. issue 1. 2001-09-06. PMID:11509028. |
alterations in the nasal turbinates lined by olfactory mucosa were identified 1, 3, and 6 days postadministration of 3-mi using mri. |
2001-09-06 |
2023-08-12 |
mouse |
| M Narita, A Uchimura, M Kawanabe, H Fukushi, K Hira. Invasion and spread of equine herpesvirus 9 in the olfactory pathway of pigs after intranasal inoculation. Journal of comparative pathology. vol 124. issue 4. 2001-08-30. PMID:11437502. |
ehv-9 antigen was first detected in the nasal and olfactory epithelial cells in the nasal cavity, and in the neuroglial cells in the olfactory bulb. |
2001-08-30 |
2023-08-12 |
Not clear |
| J A St John, B Ke. Chemically and morphologically identifiable glomeruli in the rat olfactory bulb. The Journal of comparative neurology. vol 436. issue 4. 2001-08-30. PMID:11447592. |
primary olfactory neurons that express the same odorant receptor are distributed mosaically throughout the olfactory neuroepithelium lining the nasal cavity, yet their axons converge and form discrete glomeruli in the olfactory bulb. |
2001-08-30 |
2023-08-12 |
rat |
| J Heydel, S Leclerc, P Bernard, H Pelczar, D Gradinaru, J Magdalou, A Minn, Y Artur, H Goudonne. Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis. Brain research. Molecular brain research. vol 90. issue 1. 2001-08-23. PMID:11376859. |
beside the diverse ugt isoforms present in the liver as well as in other tissues, the ugt2a1 isoform, also called olfactory ugt, was initially thought to be expressed in the nasal epithelium only. |
2001-08-23 |
2023-08-12 |
mouse |
| C R Wirsig-Wiechman. Function of gonadotropin-releasing hormone in olfaction. The Keio journal of medicine. vol 50. issue 2. 2001-08-02. PMID:11450596. |
in all vertebrate species, except in sharks where it is a separate nerve, the nervus terminalis consists of a chain of neurons embedded within olfactory or vomeronasal nerves in the nasal cavity. |
2001-08-02 |
2023-08-12 |
Not clear |
| J C Walker, M Kendal-Reed, S B Hall, W T Morgan, V V Polyakov, R W Lut. Human responses to propionic acid. II. Quantification of breathing responses and their relationship to perception. Chemical senses. vol 26. issue 4. 2001-07-26. PMID:11369670. |
in view of the failure of prior work to provide evidence that olfactory activation alone can cause any of the breathing changes we observed, we conclude that some breathing parameters are quite useful as rapid and sensitive measures of nasal irritation that arises from activation of nasal trigeminal afferents alone or in combination with the olfactory nerve. |
2001-07-26 |
2023-08-12 |
human |
| R Ramoni, F Vincent, S Grolli, V Conti, C Malosse, F D Boyer, P Nagnan-Le Meillour, S Spinelli, C Cambillau, M Tegon. The insect attractant 1-octen-3-ol is the natural ligand of bovine odorant-binding protein. The Journal of biological chemistry. vol 276. issue 10. 2001-07-19. PMID:11114310. |
bovine odorant-binding protein (bobp) is a dimeric lipocalin present in large amounts in the respiratory and olfactory nasal mucosa. |
2001-07-19 |
2023-08-12 |
cattle |
| M S Bogdanffy, D R Plowchalk, R Sarangapani, T B Starr, M E Anderse. Mode-of-action-based dosimeters for interspecies extrapolation of vinyl acetate inhalation risk. Inhalation toxicology. vol 13. issue 5. 2001-06-28. PMID:11295869. |
vinyl acetate is a nasal carcinogen in rats and induces olfactory degeneration in rats and mice. |
2001-06-28 |
2023-08-12 |
mouse |
| M E Andersen, R Sarangapan. Physiologically based clearance/extraction models for compounds metabolized in the nose: an example with methyl methacrylate. Inhalation toxicology. vol 13. issue 5. 2001-06-28. PMID:11295870. |
it consists of mucus:air and blood:air partition coefficients, metabolic constants for enzymatic hydrolysis in nasal tissues from rat and human tissues, immunohistochemistry of the distribution of these activities in rats and human olfactory tissues, and extraction studies in anesthetized rats to assess the total nasal metabolism of the test compound. |
2001-06-28 |
2023-08-12 |
human |
| J Lu, F Féron, S M Ho, A Mackay-Sim, P M Wait. Transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats. Brain research. vol 889. issue 1-2. 2001-05-17. PMID:11166728. |
transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats. |
2001-05-17 |
2023-08-12 |
human |
| J Lu, F Féron, S M Ho, A Mackay-Sim, P M Wait. Transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats. Brain research. vol 889. issue 1-2. 2001-05-17. PMID:11166728. |
in humans a source of these cells for autologous therapy lies in the nasal mucosa where they accompany the axons of the olfactory neurons. |
2001-05-17 |
2023-08-12 |
human |
| J Lu, F Féron, S M Ho, A Mackay-Sim, P M Wait. Transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats. Brain research. vol 889. issue 1-2. 2001-05-17. PMID:11166728. |
the aim of the present study was to test the therapeutic potential of nasal olfactory ensheathing cells for spinal cord repair. |
2001-05-17 |
2023-08-12 |
human |
| J A St John, B Ke. EphB2 and two of its ligands have dynamic protein expression patterns in the developing olfactory system. Brain research. Developmental brain research. vol 126. issue 1. 2001-05-17. PMID:11172885. |
primary olfactory neurons are located in the olfactory neuroepithelium lining the nasal cavity. |
2001-05-17 |
2023-08-12 |
rat |
| F W Sunderma. Nasal toxicity, carcinogenicity, and olfactory uptake of metals. Annals of clinical and laboratory science. vol 31. issue 1. 2001-05-17. PMID:11314863. |
nasal toxicity, carcinogenicity, and olfactory uptake of metals. |
2001-05-17 |
2023-08-12 |
Not clear |
| F W Sunderma. Nasal toxicity, carcinogenicity, and olfactory uptake of metals. Annals of clinical and laboratory science. vol 31. issue 1. 2001-05-17. PMID:11314863. |
occupational exposures to inhalation of certain metal dusts or aerosols can cause loss of olfactory acuity, atrophy of the nasal mucosa, mucosal ulcers, perforated nasal septum, or sinonasal cancer. |
2001-05-17 |
2023-08-12 |
Not clear |
| F W Sunderma. Nasal toxicity, carcinogenicity, and olfactory uptake of metals. Annals of clinical and laboratory science. vol 31. issue 1. 2001-05-17. PMID:11314863. |
after nasal instillation of a metal-containing solution, transport of the metal via olfactory axons can occur rapidly, within hours or a few days (eg, mn), or slowly over days or weeks (eg, ni). |
2001-05-17 |
2023-08-12 |
Not clear |
| R D Mattes, D DiMegli. Ethanol perception and ingestion. Physiology & behavior. vol 72. issue 1-2. 2001-05-10. PMID:11240000. |
sessions involved determination of taste, olfactory and nasal irritation thresholds for ethanol, taste thresholds for tetralone, suprathreshold intensity and quality judgements, determination of phenylthiocarbamide (ptc) taster status, acute oral exposure effect of ethanol on ratings for sucrose, nacl, citric acid and quinine hydrochloride and hedonic judgments of beers. |
2001-05-10 |
2023-08-12 |
Not clear |
| F J Roisen, K M Klueber, C L Lu, L M Hatcher, A Dozier, C B Shields, S Maguir. Adult human olfactory stem cells. Brain research. vol 890. issue 1. 2001-04-26. PMID:11164764. |
in contrast, olfactory neuroepithelium (one) located in the nasal passageways has a continuous regenerative capability and can be biopsied readily. |
2001-04-26 |
2023-08-12 |
human |