| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T H Faller, G A Csanády, P E Kreuzer, C M Baur, J G Filse. Kinetics of propylene oxide metabolism in microsomes and cytosol of different organs from mouse, rat, and humans. Toxicology and applied pharmacology. vol 172. issue 1. 2001-04-26. PMID:11264024. |
kinetics of the metabolic inactivation of 1,2-epoxypropane (propylene oxide; po) catalyzed by glutathione s-transferase (gst) and by epoxide hydrolase (eh) were investigated at 37 degrees c in cytosol and microsomes of liver and lung of b6c3f1 mice, f344 rats, and humans and of respiratory and olfactory nasal mucosa of f344 rats. |
2001-04-26 |
2023-08-12 |
mouse |
| Y Hagiwara, T Iwasaki, H Asanuma, Y Sato, T Sata, C Aizawa, T Kurata, S Tamur. Effects of intranasal administration of cholera toxin (or Escherichia coli heat-labile enterotoxin) B subunits supplemented with a trace amount of the holotoxin on the brain. Vaccine. vol 19. issue 13-14. 2001-04-19. PMID:11166888. |
intracerebral injection of ctb* at doses more than 10 microg/mouse caused significant body weight loss and dose-dependent death within 7 days, with localization of conjugates of horseradish peroxidase with ctb (hrp-ctb) in the ventricular system and in the perineural space of olfactory nerves of the nasal mucosa 3 h after injection. |
2001-04-19 |
2023-08-12 |
mouse |
| J E Barrett, M G King, G Pan. Conditioning rhinitis in allergic humans. Annals of the New York Academy of Sciences. vol 917. 2001-04-19. PMID:11268416. |
a classical pavlovian paradigm pairing an olfactory cue with allergen challenge for a single training trial was used to produce conditioned histamine release and conditioned nasal airflow decrease in seasonal allergic rhinitis sufferers. |
2001-04-19 |
2023-08-12 |
Not clear |
| J Stanek, G de Courten-Myers, A G Spaulding, W Strub, R J Hopki. Case of complex craniofacial anomalies, bilateral nasal proboscides, palatal pituitary, upper limbs reduction, and amnion rupture sequence: disorganization phenotype? Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. vol 4. issue 2. 2001-04-12. PMID:11178637. |
the anomalies include the following: lateral and midline cleft upper lip, ectopic palatal pituitary, natal teeth, bilateral nasal proboscides with an absent nose, left microphthalmia with conjunctival-lined cyst, right ocular dysgenesis, bilateral retinal dysplasia, platybasia with skull asymmetry, hydrocephalus secondary to aqueductal atresia, brain hemispheric asymmetry with a parietal-occipital cortical flap, agenesis of posterior corpus callosum, absence of the olfactory nerves and left anterior cerebral artery, leptomeningeal and intraventricular heterotopias, right radial longitudinal terminal meromelia with constriction rings of fingers, partial syndactyly of the third and fourth left fingers, dorsiflexed great toes and pes equinovarus bilaterally, and multiple skin tags with a sacral appendage. |
2001-04-12 |
2023-08-12 |
human |
| H J Clarris, B Ke. Expression of glycoproteins in the vomeronasal organ reveals a novel spatiotemporal pattern of sensory neurone maturation. Journal of neurobiology. vol 46. issue 2. 2001-03-08. PMID:11153013. |
the primary sensory neurones of the accessory olfactory system are sequestered in the vomeronasal organ (vno), where they express pheromone receptors, which are unrelated to the odorant receptors expressed in the principal nasal cavity. |
2001-03-08 |
2023-08-12 |
mouse |
| J M Ward, M Yoon, M R Anver, D C Haines, G Kudo, F J Gonzalez, S Kimur. Hyalinosis and Ym1/Ym2 gene expression in the stomach and respiratory tract of 129S4/SvJae and wild-type and CYP1A2-null B6, 129 mice. The American journal of pathology. vol 158. issue 1. 2001-02-22. PMID:11141507. |
immunohistochemistry, using rabbit polyclonal antibodies to oligopeptides derived from the ym1 sequence, detected focal to diffuse reactivity within both normal and abnormal nasal olfactory and respiratory epithelium, pulmonary alveolar macrophages, bone marrow myeloid cells, and the squamous epithelium of the forestomach and epithelium of the glandular stomach. |
2001-02-22 |
2023-08-12 |
mouse |
| A Taniguchi, H Fukushi, T Yanai, T Masegi, T Yamaguchi, K Hira. Equine herpesvirus 9 induced lethal encephalomyelitis in experimentally infected goats. Archives of virology. vol 145. issue 12. 2001-02-15. PMID:11205108. |
ehv-9 was recovered from peripheral white blood cells, the olfactory bulbs and brain, nasal swabs, concha, and lungs. |
2001-02-15 |
2023-08-12 |
Not clear |
| M B Genter, D M Burman, M W Dingeldein, I Clough, B Bolo. Evolution of alachlor-induced nasal neoplasms in the Long-Evans rat. Toxicologic pathology. vol 28. issue 6. 2001-02-08. PMID:11127290. |
six months of alachlor exposure resulted in proliferation of basal and nonbasal cells in the olfactory mucosa while inducing nasal masses in 7 of 15 animals. |
2001-02-08 |
2023-08-12 |
rat |
| M B Genter, D M Burman, M W Dingeldein, I Clough, B Bolo. Evolution of alachlor-induced nasal neoplasms in the Long-Evans rat. Toxicologic pathology. vol 28. issue 6. 2001-02-08. PMID:11127290. |
tumors ranged from dysplastic plaques to polypoid adenomas and originated in the olfactory regions of the nasal cavity. |
2001-02-08 |
2023-08-12 |
rat |
| K A Brenneman, B A Wong, M A Buccellato, E R Costa, E A Gross, D C Dorma. Direct olfactory transport of inhaled manganese ((54)MnCl(2)) to the rat brain: toxicokinetic investigations in a unilateral nasal occlusion model. Toxicology and applied pharmacology. vol 169. issue 3. 2001-02-02. PMID:11133346. |
direct olfactory transport of inhaled manganese ((54)mncl(2)) to the rat brain: toxicokinetic investigations in a unilateral nasal occlusion model. |
2001-02-02 |
2023-08-12 |
human |
| A M Seiden, H J Dunca. The diagnosis of a conductive olfactory loss. The Laryngoscope. vol 111. issue 1. 2001-02-01. PMID:11192906. |
two of the most common causes of olfactory loss include upper respiratory infection (uri) and nasal or sinus disease. |
2001-02-01 |
2023-08-12 |
Not clear |
| I Kratskin, T Hummel, L Hastings, R Dot. 3-Methylindole alters both olfactory and trigeminal nasal mucosal potentials in rats. Neuroreport. vol 11. issue 10. 2001-01-25. PMID:10923669. |
3-methylindole alters both olfactory and trigeminal nasal mucosal potentials in rats. |
2001-01-25 |
2023-08-12 |
human |
| I Kratskin, T Hummel, L Hastings, R Dot. 3-Methylindole alters both olfactory and trigeminal nasal mucosal potentials in rats. Neuroreport. vol 11. issue 10. 2001-01-25. PMID:10923669. |
the results suggest that 3-mi affects both olfactory and trigeminal elements within the nasal mucosa. |
2001-01-25 |
2023-08-12 |
human |
| E Racekova, A Fercakova, J Orendacov. [Neural stem cells: possibilities of regeneration in the adult CNS]. Bratislavske lekarske listy. vol 101. issue 8. 2001-01-25. PMID:11153170. |
nevertheless, it has now been ascertained that these phenomena can occur in the adult mammalian nervous system, at least in three distinct sites: the olfactory neuroepithelium of the nasal mucosa and two brain regions, namely, the hippocampal dentate gyrus and the olfactory bulb. |
2001-01-25 |
2023-08-12 |
Not clear |
| M A Chapu. EOG responses in anesthetized freely breathing rats. Chemical senses. vol 25. issue 6. 2001-01-11. PMID:11114147. |
thus, anesthetized, freely breathing rats were used to record from the olfactory mucosa in the intact nasal cavity (electroolfactogram or eog) so as to study global response characteristics to odor stimuli. |
2001-01-11 |
2023-08-12 |
rat |
| D Tsuchiya, T Kayama, H Kuchiki, S Sato, S Sait. [A case of olfactory neuroblastoma with intracranial extension and distant metastasis]. No to shinkei = Brain and nerve. vol 52. issue 9. 2001-01-05. PMID:11064869. |
olfactory neuroblastoma is a rare tumor originating in the upper nasal cavity. |
2001-01-05 |
2023-08-12 |
Not clear |
| L S Mullin, G L Kennedy, C K Woo. Nasal tumors in rats following long-term inhalation exposure to 1,4-dichlorobutene-2 (DCB). Drug and chemical toxicology. vol 23. issue 3. 2000-12-28. PMID:10959544. |
malignant nasal tumors occurred in the olfactory region of the nasal cavity and were statistically increased at 1.0 ppm. |
2000-12-28 |
2023-08-12 |
rat |
| D W Parsons, P J Hopkins, A J Bourne, R C Boucher, A J Marti. Airway gene transfer in mouse nasal-airways: importance of identification of epithelial type for assessment of gene transfer. Gene therapy. vol 7. issue 21. 2000-12-22. PMID:11110412. |
however, the mouse nasal cavity is lined by both olfactory (oe) and respiratory epithelium (re). |
2000-12-22 |
2023-08-12 |
mouse |
| M N Ríos-Blanco, T H Faller, J Nakamura, W Kessler, P E Kreuzer, A Ranasinghe, J G Filser, J A Swenber. Quantitation of DNA and hemoglobin adducts and apurinic/apyrimidinic sites in tissues of F344 rats exposed to propylene oxide by inhalation. Carcinogenesis. vol 21. issue 11. 2000-12-14. PMID:11062162. |
in animals killed up to 7 h following the end of the last exposure the levels of 7-hpg (pmol/micromol guanine) in nasal respiratory tissue, nasal olfactory tissue, lung, spleen, liver and testis dna were 606.2 +/- 53.0, 297.5 +/- 56.5, 69.8 +/- 3.8, 43.0 +/- 3.8, 27.5 +/- 2.4 and 14.2 +/- 0.7, respectively. |
2000-12-14 |
2023-08-12 |
rat |
| T Koujitani, K Yasuhara, T Ikeda, T Imazawa, T Tamura, K Toyosawa, A Shimada, M Hirose, K Mitsumor. Sequential observation of 2,6-dimethylaniline-induced nasal lesions in a rat two-stage nasal carcinogenesis model after initiation with N-bis(2-hydroxypropyl) nitrosamine. The Journal of veterinary medical science. vol 62. issue 7. 2000-12-07. PMID:10945294. |
these nasal lesions were mostly evident in the olfactory mucosa in the nasal cavity, and their severity and/or incidences, other than atrophy of bowman's glands, increased with the treatment period. |
2000-12-07 |
2023-08-12 |
rat |