| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takaki Miwa, Tetsuji Moriizumi, Isao Horikawa, Naoki Uramoto, Tadashi Ishimaru, Toshiro Nishimura, Mitsuru Furukaw. Role of nerve growth factor in the olfactory system. Microscopy research and technique. vol 58. issue 3. 2003-01-29. PMID:12203698. |
administration of ngf directory into nasal cavity results in an increase in the expression of olfactory marker protein within the olfactory epithelium in axotomized rats. |
2003-01-29 |
2023-08-12 |
mouse |
| Minghong Ma, Xavier Grosmaitre, Carrie L Iwema, Harriet Baker, Charles A Greer, Gordon M Shepher. Olfactory signal transduction in the mouse septal organ. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 1. 2003-01-27. PMID:12514230. |
the septal organ, a distinct chemosensory organ observed in the mammalian nose, is essentially a small island of olfactory neuroepithelium located bilaterally at the ventral base of the nasal septum. |
2003-01-27 |
2023-08-12 |
mouse |
| V I Gulimov. [Human and animal vomeronasal systems in health and disease]. Arkhiv patologii. vol 64. issue 4. 2003-01-22. PMID:12402561. |
the vomeronasal organ (vo) or the second olfactory organ has the form of paired epithelial pockets at the base of the nasal septum. |
2003-01-22 |
2023-08-12 |
human |
| Dennis Shusterma. Individual factors in nasal chemesthesis. Chemical senses. vol 27. issue 6. 2003-01-21. PMID:12142331. |
candidate susceptibility markers include age, gender, presence or absence of nasal allergies or olfactory dysfunction, cognitive bias and self-reported pollutant reactivity. |
2003-01-21 |
2023-08-12 |
Not clear |
| Elena P Goncharova, Alexander B Ryzhikov, Leonid E Bulychev, Alexander A Sizov, Leonid R Lebedev, Vasiliy D Poryvaev, Larisa I Karpenko, Alexander A Il'iche. A study of systems for delivering antigens and plasmid DNA for intranasal immunization against tick-borne encephalitis virus. Wiener klinische Wochenschrift. vol 114. issue 13-14. 2003-01-16. PMID:12422616. |
thus, nasal mucosa in the olfactory region is likely to be a promising target for mucosal immunization to protect the cns from neurotropic viral infections. |
2003-01-16 |
2023-08-12 |
mouse |
| S Stefańczyk-Krzymowska, B Wasowska, B Jan. Boar pheromone androstenol may affect the ovarian morphology in cycling gilts by humoral pathway. Folia histochemica et cytobiologica. vol 40. issue 2. 2003-01-09. PMID:12056622. |
up to 1999 it was accepted that pheromones act exclusively by stimulation of dendritic receptors of olfactory neurons massed in the olfactory epithelium, but in 1999-2000, the presence of local humoral pathway for transfer of boar pheromone androstenol from the nasal cavity to the hypophysis and brain was demonstrated in gilts. |
2003-01-09 |
2023-08-12 |
Not clear |
| Alain Minn, Séverine Leclerc, Jean-Marie Heydel, Anne-Laure Minn, Claire Denizcot, Martine Cattarelli, Patrick Netter, Daniela Gradinar. Drug transport into the mammalian brain: the nasal pathway and its specific metabolic barrier. Journal of drug targeting. vol 10. issue 4. 2002-12-23. PMID:12164377. |
this short review summarizes recent knowledge on factors controlling the nasal pathway, focusing on drug metabolising enzymes in olfactory mucosa, olfactory bulb and brain, which should constitute a cns metabolic barrier. |
2002-12-23 |
2023-08-12 |
Not clear |
| J Dürr, J Lindemann, T Kec. [Sense of smell before and after functional esthetic rhinoplasty]. HNO. vol 50. issue 7. 2002-12-04. PMID:12219671. |
the aim of the present study was to determine possible changes in olfactory threshold after functional and esthetic nasal operations and to evaluate whether these changes were recognized by the patients. |
2002-12-04 |
2023-08-12 |
Not clear |
| David C Dorman, Karrie A Brenneman, Anna M McElveen, Sean E Lynch, Kay C Roberts, Brian A Won. Olfactory transport: a direct route of delivery of inhaled manganese phosphate to the rat brain. Journal of toxicology and environmental health. Part A. vol 65. issue 20. 2002-12-03. PMID:12396865. |
growing evidence suggests that nasal deposition and transport along olfactory neurons represents another route by which inhaled manganese is delivered to certain regions of the rat brain. |
2002-12-03 |
2023-08-12 |
rat |
| Kohtaro Fujihashi, Toshiya Koga, Frederik W van Ginkel, Yukari Hagiwara, Jerry R McGhe. A dilemma for mucosal vaccination: efficacy versus toxicity using enterotoxin-based adjuvants. Vaccine. vol 20. issue 19-20. 2002-11-27. PMID:12057597. |
when we examined potential toxicity of ct for the central nervous system (cns), both ct and ct-b accumulated in the olfactory nerves/epithelium and olfactory bulbs of mice when given by the nasal route. |
2002-11-27 |
2023-08-12 |
mouse |
| Kiyonori Kai, Hiroshi Satoh, Yoshinori Kashimoto, Tetsuyo Kajimura, Kazuhisa Furuham. Olfactory epithelium as a novel toxic target following an intravenous administration of vincristine to mice. Toxicologic pathology. vol 30. issue 3. 2002-11-20. PMID:12051547. |
these results demonstrate that it is essential to perform histopathological evaluation of the nasal mucosa during an early preclinical stage for novel antitumor drugs, since olfactory lesions due to the certain compounds like vcr may not be detected by any other procedure. |
2002-11-20 |
2023-08-12 |
mouse |
| Lilian Calderón-Garcidueñas, Biagio Azzarelli, Hilda Acuna, Raquel Garcia, Todd M Gambling, Norma Osnaya, Sylvia Monroy, Maria Rosario DEL Tizapantzi, Johnny L Carson, Anna Villarreal-Calderon, Barry Rewcastl. Air pollution and brain damage. Toxicologic pathology. vol 30. issue 3. 2002-11-20. PMID:12051555. |
because the nasal cavity is a common portal of entry, respiratory and olfactory epithelia are vulnerable targets for toxicological damage. |
2002-11-20 |
2023-08-12 |
Not clear |
| Lilian Calderón-Garcidueñas, Biagio Azzarelli, Hilda Acuna, Raquel Garcia, Todd M Gambling, Norma Osnaya, Sylvia Monroy, Maria Rosario DEL Tizapantzi, Johnny L Carson, Anna Villarreal-Calderon, Barry Rewcastl. Air pollution and brain damage. Toxicologic pathology. vol 30. issue 3. 2002-11-20. PMID:12051555. |
this study has evaluated, by light and electron microscopy and immunohistochemical expression of nuclear factor-kappa beta (nf-kappab) and inducible nitric oxide synthase (inos), the olfactory and respiratory nasal mucosae, olfactory bulb, and cortical and subcortical structures from 32 healthy mongrel canine residents in southwest metropolitan mexico city (swmmc), a highly polluted urban region. |
2002-11-20 |
2023-08-12 |
Not clear |
| M Kriet, A Laktaoui, S Zrara, N Harmouchi, H Souhail, H Chana, A Terhza. [Olfactory esthesioneuroblastoma with an ophtalmological presentation: a case report]. Journal francais d'ophtalmologie. vol 25. issue 6. 2002-10-30. PMID:12223953. |
esthesioneuroblastoma (enb) is a rare malignant tumor, which develops from the olfactory neuroepithelium and is one of the rarest tumors of the nasal cavity. |
2002-10-30 |
2023-08-12 |
Not clear |
| Giancarlo Renzi, Andrea Carboni, Giulio Gasparini, Maurizio Perugini, Roberto Becell. Taste and olfactory disturbances after upper and middle third facial fractures: a preliminary study. Annals of plastic surgery. vol 48. issue 4. 2002-10-21. PMID:12068215. |
nasal fractures, nasoorbital-ethmoidal fractures, ethmoidal fractures, frontal-le fort fractures, and nasal-le fort fractures did not determine any olfactory dysfunction. |
2002-10-21 |
2023-08-12 |
Not clear |
| Leonardo Belluscio, Claudia Lodovichi, Paul Feinstein, Peter Mombaerts, Lawrence C Kat. Odorant receptors instruct functional circuitry in the mouse olfactory bulb. Nature. vol 419. issue 6904. 2002-10-21. PMID:12239567. |
the mammalian olfactory system detects and discriminates thousands of odorants using many different receptors expressed by sensory neurons in the nasal epithelium. |
2002-10-21 |
2023-08-12 |
mouse |
| Clay B Frederick, Larry G Lomax, Kurt A Black, Lavorgie Finch, Harvey E Scribner, Julia S Kimbell, Kevin T Morgan, Ravi P Subramaniam, John B Morri. Use of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry comparisons of ester vapors. Toxicology and applied pharmacology. vol 183. issue 1. 2002-09-24. PMID:12217639. |
an in vitro exposure of explants of rat olfactory epithelium to ea with and without an esterase inhibitor demonstrated that the organic acid, acrylic acid, released by nasal esterases is primarily responsible for the olfactory cytotoxicity. |
2002-09-24 |
2023-08-12 |
human |
| Clay B Frederick, Larry G Lomax, Kurt A Black, Lavorgie Finch, Harvey E Scribner, Julia S Kimbell, Kevin T Morgan, Ravi P Subramaniam, John B Morri. Use of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry comparisons of ester vapors. Toxicology and applied pharmacology. vol 183. issue 1. 2002-09-24. PMID:12217639. |
estimates of the steady-state concentration of acrylic acid in olfactory tissue were made for the rat nasal cavity by using data from a series of short-term in vivo studies and from the results of cfd-pbpk computer modeling. |
2002-09-24 |
2023-08-12 |
human |
| Clay B Frederick, Larry G Lomax, Kurt A Black, Lavorgie Finch, Harvey E Scribner, Julia S Kimbell, Kevin T Morgan, Ravi P Subramaniam, John B Morri. Use of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry comparisons of ester vapors. Toxicology and applied pharmacology. vol 183. issue 1. 2002-09-24. PMID:12217639. |
the increased olfactory tissue dose in rats relative to humans may be attributed to both the vulnerable location of the rodent olfactory tissue (comprising greater than 50% of the nasal cavity) and the high concentration of rat olfactory esterase activity (comparable to liver esterase activity) relative to human olfactory tissue. |
2002-09-24 |
2023-08-12 |
human |
| G Brand, J L Millot, M Saffaux, N Morand-Villeneuv. Lateralization in human nasal chemoreception: differences in bilateral electrodermal responses related to olfactory and trigeminal stimuli. Behavioural brain research. vol 133. issue 2. 2002-09-19. PMID:12110454. |
lateralization in human nasal chemoreception: differences in bilateral electrodermal responses related to olfactory and trigeminal stimuli. |
2002-09-19 |
2023-08-12 |
human |