| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adam B Salmon, Chad Lerner, Yuji Ikeno, Susan M Motch Perrine, Roger McCarter, Christian Sel. Altered metabolism and resistance to obesity in long-lived mice producing reduced levels of IGF-I. American journal of physiology. Endocrinology and metabolism. vol 308. issue 7. 2015-06-12. PMID:25648834. |
in control animals, insulin response was significantly impaired by high-fat feeding, whereas igf-i-deficient mice showed a much smaller shift in insulin response after high-fat feeding. |
2015-06-12 |
2023-08-13 |
mouse |
| Adam B Salmon, Chad Lerner, Yuji Ikeno, Susan M Motch Perrine, Roger McCarter, Christian Sel. Altered metabolism and resistance to obesity in long-lived mice producing reduced levels of IGF-I. American journal of physiology. Endocrinology and metabolism. vol 308. issue 7. 2015-06-12. PMID:25648834. |
these results indicate that reduction in the circulating and tissue igf-i levels can produce a metabolic phenotype in female mice that increases peripheral insulin resistance but renders animals resistant to the deleterious effects of high-fat feeding. |
2015-06-12 |
2023-08-13 |
mouse |
| Emma K Lees, Elżbieta Król, Louise Grant, Kirsty Shearer, Cathy Wyse, Eleanor Moncur, Aleksandra S Bykowska, Nimesh Mody, Thomas W Gettys, Mirela Delibegovi. Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. Aging cell. vol 13. issue 5. 2015-06-11. PMID:24935677. |
our findings suggest that mr feeding can reverse the negative effects of aging on body mass, adiposity, and insulin resistance through an fgf21 mechanism. |
2015-06-11 |
2023-08-13 |
mouse |
| Kenjiro Muta, Donald A Morgan, Kamal Rahmoun. The role of hypothalamic mTORC1 signaling in insulin regulation of food intake, body weight, and sympathetic nerve activity in male mice. Endocrinology. vol 156. issue 4. 2015-06-11. PMID:25574706. |
the role of hypothalamic mtorc1 signaling in insulin regulation of food intake, body weight, and sympathetic nerve activity in male mice. |
2015-06-11 |
2023-08-13 |
mouse |
| Susanne E la Fleur, Mireille J Serli. The interaction between nutrition and the brain and its consequences for body weight gain and metabolism; studies in rodents and men. Best practice & research. Clinical endocrinology & metabolism. vol 28. issue 5. 2015-06-10. PMID:25256761. |
aberrant feeding behavior can lead to obesity and obesity-related medical consequences, such as insulin resistance and diabetes. |
2015-06-10 |
2023-08-13 |
human |
| Soraia Poloni, Henk J Blom, Ida V D Schwart. Stearoyl-CoA Desaturase-1: Is It the Link between Sulfur Amino Acids and Lipid Metabolism? Biology. vol 4. issue 2. 2015-06-06. PMID:26046927. |
this enzyme also appears to be involved in the etiology of metabolic syndromes because its suppression results in decreased fat deposits (regardless of food intake), improved insulin sensitivity and higher basal energy expenditure. |
2015-06-06 |
2023-08-13 |
Not clear |
| Panpan Wu, Ping He, Suqing Zhao, Tianming Huang, Yujing Lu, Kun Zhan. Effects of ursolic acid derivatives on Caco-2 cells and their alleviating role in streptozocin-induced type 2 diabetic rats. Molecules (Basel, Switzerland). vol 19. issue 8. 2015-06-05. PMID:25153871. |
further in vivo studies revealed that compound 10 significantly reduced hyperglycemia by increasing levels of serum insulin, total protein, and albumin, while the fasting blood glucose, body weight and food intake were restored much closer to those of normal rats. |
2015-06-05 |
2023-08-13 |
rat |
| Hilda E Ghadieh, Zachary N Smiley, Melissa W Kopfman, Mona G Najjar, Michael J Hake, Sonia M Najja. Chlorogenic acid/chromium supplement rescues diet-induced insulin resistance and obesity in mice. Nutrition & metabolism. vol 12. 2015-06-05. PMID:26045713. |
the current study investigates whether a chlorogenic acid/chromium iii supplement rescues obesity and insulin resistance caused by high-fat feeding of male c57bl/6 j mice for 7 weeks. |
2015-06-05 |
2023-08-13 |
mouse |
| Hilda E Ghadieh, Zachary N Smiley, Melissa W Kopfman, Mona G Najjar, Michael J Hake, Sonia M Najja. Chlorogenic acid/chromium supplement rescues diet-induced insulin resistance and obesity in mice. Nutrition & metabolism. vol 12. 2015-06-05. PMID:26045713. |
administering an oral daily dose of this supplement in the last 3 weeks of feeding reversed diet-induced body weight gain and insulin resistance, assessed by hyperglycemia, glucose intolerance and insulin intolerance. |
2015-06-05 |
2023-08-13 |
mouse |
| William T Festuccia, Philippe Pouliot, Inan Bakan, David M Sabatini, Mathieu Laplant. Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide. PloS one. vol 9. issue 4. 2015-06-01. PMID:24740015. |
although high fat feeding contributed to promote obesity, inflammation, macrophage infiltration in adipose tissue and systemic insulin resistance, we did not observe a significant impact of rictor loss on these parameters. |
2015-06-01 |
2023-08-13 |
mouse |
| John Joseph Valletta, Andrew J Chipperfield, Geraldine F Clough, Christopher D Byrn. Daily energy expenditure, cardiorespiratory fitness and glycaemic control in people with type 1 diabetes. PloS one. vol 9. issue 5. 2015-06-01. PMID:24826899. |
however, increasing physical activity often creates a challenge for people with type 1 diabetes, because of difficulties maintaining euglycemia in the face of altered food intake and adjustments to insulin doses. |
2015-06-01 |
2023-08-13 |
human |
| A Picard, V S Moullé, C Le Foll, C Cansell, J Véret, N Coant, H Le Stunff, S Migrenne, S Luquet, C Cruciani-Guglielmacci, B E Levin, C Magna. Physiological and pathophysiological implications of lipid sensing in the brain. Diabetes, obesity & metabolism. vol 16 Suppl 1. 2015-06-01. PMID:25200296. |
through neuronal output, fa may modulate feeding behaviour as well as insulin secretion and action. |
2015-06-01 |
2023-08-13 |
human |
| T Yada, B Damdindorj, R S Rita, T Kurashina, A Ando, M Taguchi, M Koizumi, H Sone, M Nakata, M Kakei, K Dezak. Ghrelin signalling in β-cells regulates insulin secretion and blood glucose. Diabetes, obesity & metabolism. vol 16 Suppl 1. 2015-06-01. PMID:25200304. |
ghrelin, initially identified as a potent stimulator of gh release and feeding, has been shown to suppress glucose-induced insulin release. |
2015-06-01 |
2023-08-13 |
mouse |
| Matthew D Campbell, Mark Walker, Richard M Bracken, Daniel Turner, Emma J Stevenson, Javier T Gonzalez, James A Shaw, Daniel J Wes. Insulin therapy and dietary adjustments to normalize glycemia and prevent nocturnal hypoglycemia after evening exercise in type 1 diabetes: a randomized controlled trial. BMJ open diabetes research & care. vol 3. issue 1. 2015-05-28. PMID:26019878. |
therefore, this study aimed to examine the impact of a combined basal-bolus insulin dose reduction and carbohydrate feeding strategy on glycemia and metabolic parameters following evening exercise in type 1 diabetes. |
2015-05-28 |
2023-08-13 |
Not clear |
| Ana Luiza R Rolim, Susan C Lindsey, Ilda S Kunii, Felipe Crispim, Regina Célia M S Moisés, Rui M B Maciel, Magnus R Dias-da-Silv. The insulin-sensitivity sulphonylurea receptor variant is associated with thyrotoxic paralysis. Journal of molecular endocrinology. vol 53. issue 2. 2015-05-22. PMID:25143473. |
the sulphonylurea receptor 1 (sur1 (abcc8)) is an essential regulatory subunit of the β-cell atp-sensitive k(+) channel that controls insulin secretion after feeding. |
2015-05-22 |
2023-08-13 |
Not clear |
| Yuanchao Ye, Zhizeng Sun, Ang Guo, Long-Sheng Song, Justin L Grobe, Songhai Che. Ablation of the GNB3 gene in mice does not affect body weight, metabolism or blood pressure, but causes bradycardia. Cellular signalling. vol 26. issue 11. 2015-05-15. PMID:25093805. |
gβ3-deficient mice were normal as judged by body weight gain by age or by feeding with high-fat diet (hfd); glucose tolerance and insulin sensitivity; baseline blood pressure and angiotensin ii infusion-induced hypertension. |
2015-05-15 |
2023-08-13 |
mouse |
| Tae-Jin Ju, Woo-Young Kwon, Yong-Woon Kim, Jong-Yeon Kim, Yong-Dae Kim, In-Kyu Lee, So-Young Par. Hemin improves insulin sensitivity in skeletal muscle in high fat-fed mice. Journal of pharmacological sciences. vol 126. issue 2. 2015-05-12. PMID:25341564. |
a four-week high-fat feeding to mice increased the body weight, fat mass, and plasma levels of insulin and lipid, which were reduced by hemin. |
2015-05-12 |
2023-08-13 |
mouse |
| S M Kissler, C Cichowitz, S Sankaranarayanan, D M Bort. Determination of personalized diabetes treatment plans using a two-delay model. Journal of theoretical biology. vol 359. 2015-05-11. PMID:24931673. |
building upon recent successes in mathematical modeling of the human glucose-insulin system, we show that both food intake and insulin therapy likely demand increasingly precise control over insulin sensitivity if oscillations at a healthy average glucose concentration are to be maintained. |
2015-05-11 |
2023-08-13 |
human |
| Linjie Sun, Yan Wang, Yu Song, Xiang-Rong Cheng, Shufang Xia, Md Ramim Tanver Rahman, Yonghui Shi, Guowei L. Resveratrol restores the circadian rhythmic disorder of lipid metabolism induced by high-fat diet in mice. Biochemical and biophysical research communications. vol 458. issue 1. 2015-05-06. PMID:25640840. |
resveratrol, being associated with rhythmic restoration of fasting blood glucose and plasma insulin, significantly decreased the body weight in hfd mice after 11 weeks of feeding, as well as ameliorated the rhythmities of plasma leptin, lipid profiles and whole body metabolic status (respiratory exchange ratio, locomotor activity, and heat production). |
2015-05-06 |
2023-08-13 |
mouse |
| Brittany B Rice, Wei Zhang, Shiping Bai, Paul B Siegel, Mark A Cline, Elizabeth R Gilber. Insulin-induced hypoglycemia associations with gene expression changes in liver and hypothalamus of chickens from lines selected for low or high body weight. General and comparative endocrinology. vol 208. 2015-04-29. PMID:25157791. |
the lws chickens are lean and some are anorexic, while the hws are compulsive feeders and have a different threshold sensitivity of food intake and blood glucose to both central and peripheral insulin, respectively. |
2015-04-29 |
2023-08-13 |
Not clear |