| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Fernanda Condes Areias, Patricia Oliveira Prad. Mechanisms of insulin resistance in the amygdala: influences on food intake. Behavioural brain research. vol 282. 2015-09-21. PMID:25601576. |
overexpressed pkcθ in the cea (central nucleus of amygdala) of rats increases weight gain, food intake, insulin resistance and hepatic triglycerides content. |
2015-09-21 |
2023-08-13 |
human |
| Maria Fernanda Condes Areias, Patricia Oliveira Prad. Mechanisms of insulin resistance in the amygdala: influences on food intake. Behavioural brain research. vol 282. 2015-09-21. PMID:25601576. |
the inhibition of er stress ameliorates insulin action/signaling, increases oxytocin and decreases npy gene expression in the amygdala of high fat feeding rodents. |
2015-09-21 |
2023-08-13 |
human |
| Maria Fernanda Condes Areias, Patricia Oliveira Prad. Mechanisms of insulin resistance in the amygdala: influences on food intake. Behavioural brain research. vol 282. 2015-09-21. PMID:25601576. |
those data suggest that pkcθ and er stress are main mechanisms of insulin resistance in the amygdala of obese rats and play an important role regulating feeding behavior. |
2015-09-21 |
2023-08-13 |
human |
| Marine L Croze, Alain Géloën, Christophe O Soulag. Abnormalities in myo-inositol metabolism associated with type 2 diabetes in mice fed a high-fat diet: benefits of a dietary myo-inositol supplementation. The British journal of nutrition. vol 113. issue 12. 2015-09-21. PMID:25990651. |
hfd feeding for 4 months induced ectopic lipid redistribution to liver and muscles, fasting hyperglycaemia and hyperinsulinaemia, insulin resistance and obesity that were not prevented by mi supplementation, despite a significant improvement in insulin sensitivity parameter k insulin tolerance test and a reduction in white adipose tissue (wat) mass ( - 17 %, p< 0·05). |
2015-09-21 |
2023-08-13 |
mouse |
| Ziru Li, Weizhen Zhang, Michael W Mulhollan. LGR4 and Its Role in Intestinal Protection and Energy Metabolism. Frontiers in endocrinology. vol 6. 2015-09-18. PMID:26379625. |
lgr4 also contributes to regulation of energy metabolism, including food intake, energy expenditure, and lipid metabolism, as well as pancreatic β-cell proliferation and insulin secretion. |
2015-09-18 |
2023-08-13 |
Not clear |
| Kenia Pereira Bispo, Letícia de Oliveira Rodrigues, Érica da Silva Soares de Souza, Daniela Mucci, Maria das Graças Tavares do Carmo, Kelse Tibau de Albuquerque, Fatima Lucia de Carvalho Sardinh. Trans and interesterified fat and palm oil during the pregnancy and lactation period inhibit the central anorexigenic action of insulin in adult male rat offspring. The journal of physiological sciences : JPS. vol 65. issue 1. 2015-09-15. PMID:25398547. |
at 90 days, the intracerebroventricular injection of insulin decreased 24-h feeding in control rats but not in the palm, interesterified or trans groups. |
2015-09-15 |
2023-08-13 |
rat |
| Kenia Pereira Bispo, Letícia de Oliveira Rodrigues, Érica da Silva Soares de Souza, Daniela Mucci, Maria das Graças Tavares do Carmo, Kelse Tibau de Albuquerque, Fatima Lucia de Carvalho Sardinh. Trans and interesterified fat and palm oil during the pregnancy and lactation period inhibit the central anorexigenic action of insulin in adult male rat offspring. The journal of physiological sciences : JPS. vol 65. issue 1. 2015-09-15. PMID:25398547. |
we conclude that the intake of trans fatty acid substitutes during the early perinatal period affects food intake regulation in response to centrally administered insulin in the young adult offspring; however, the underlying mechanisms remain unclear. |
2015-09-15 |
2023-08-13 |
rat |
| Denovan P Begg, Aaron A May, Joram D Mul, Min Liu, David A D'Alessio, Randy J Seeley, Stephen C Wood. Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin. Diabetes. vol 64. issue 7. 2015-09-15. PMID:25667307. |
insulin signaling in the brain is catabolic, reducing food intake. |
2015-09-15 |
2023-08-13 |
mouse |
| Denovan P Begg, Aaron A May, Joram D Mul, Min Liu, David A D'Alessio, Randy J Seeley, Stephen C Wood. Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin. Diabetes. vol 64. issue 7. 2015-09-15. PMID:25667307. |
when administered acutely into the 3rd cerebral ventricle, both det and nph insulin reduced food intake and body weight at 24 h, and both food intake and body weight remained lower after det than after nph after 48 h. in direct comparison with another long-acting insulin, insulin glargine (glar), det led to more prolonged increases in csf insulin despite a shorter plasma half-life in both rats and mice. |
2015-09-15 |
2023-08-13 |
mouse |
| Alvaro Souto Padron de Figueiredo, Adam B Salmon, Francesca Bruno, Fabio Jimenez, Herman G Martinez, Ganesh V Halade, Seema S Ahuja, Robert A Clark, Ralph A DeFronzo, Hanna E Abboud, Amina El Jamal. Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet. The Journal of biological chemistry. vol 290. issue 21. 2015-09-01. PMID:25825489. |
high fat feeding increased nox2 expression, superoxide production, and impaired insulin signaling in skeletal muscle tissue of wild-type mice but not in nox2-null mice. |
2015-09-01 |
2023-08-13 |
mouse |
| Bo Liu, Shuang Song, Peter M Jones, Shanta J Persau. GPR55: from orphan to metabolic regulator? Pharmacology & therapeutics. vol 145. 2015-08-31. PMID:24972076. |
cannabinoids are known to be important in controlling appetite and metabolic balance, and it is now emerging that gpr55 may have a role to play in energy homeostasis through the regulation of food intake, fuel storage in adipocytes, gut motility and insulin secretion. |
2015-08-31 |
2023-08-13 |
Not clear |
| Carmen Huesa, Dongxing Zhu, James D Glover, Mathieu Ferron, Gerard Karsenty, Elspeth M Milne, José Luis Millan, S Faisal Ahmed, Colin Farquharson, Nicholas M Morton, Vicky E MacRa. Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes. Disease models & mechanisms. vol 7. issue 12. 2015-08-25. PMID:25368121. |
enpp1(-/-) mice exhibited mildly improved glucose homeostasis on a normal diet but showed a pronounced resistance to obesity and insulin resistance in response to chronic high-fat feeding. |
2015-08-25 |
2023-08-13 |
mouse |
| Thomas M Reinbothe, Fatemeh Safi, Annika S Axelsson, Inês G Mollet, Anders H Rosengre. Optogenetic control of insulin secretion in intact pancreatic islets with β-cell-specific expression of Channelrhodopsin-2. Islets. vol 6. issue 1. 2015-08-24. PMID:25483880. |
furthermore, light enhanced insulin release also at high glucose in these mice, suggesting that high-fat feeding leads to a compensatory potentiation of the ca(2+) response in β-cells. |
2015-08-24 |
2023-08-13 |
mouse |
| Yan-Jie Lin, Chi-Chang Juan, Ching-Fai Kwok, Yung-Pei Hsu, Kuang-Chung Shih, Chin-Chang Chen, Low-Tone H. Endothelin-1 exacerbates development of hypertension and atherosclerosis in modest insulin resistant syndrome. Biochemical and biophysical research communications. vol 460. issue 3. 2015-08-21. PMID:25824048. |
to characterize insulin signaling during modest insulin resistant syndrome, we established and monitored rats by feeding high fructose-diet (hfd) until high blood pressure and modest insulin resistance occurred. |
2015-08-21 |
2023-08-13 |
rat |
| L F Heinrich, D K Andersen, M E Cleasby, C Lawso. Long-term high fat feeding of rats results in increased numbers of circulating microvesicles with pro-inflammatory effects on endothelial cells. The British journal of nutrition. vol 113. issue 11. 2015-08-21. PMID:25880162. |
since mv are increased in plasma of obese, insulin-resistant and diabetic individuals, who often exhibit chronic vascular inflammation, and long-term feeding of a high-fat diet (hfd) to rats is a well-described model of obesity and insulin resistance, we hypothesised that this may be a useful model to study the impact of mv on endothelial inflammation. |
2015-08-21 |
2023-08-13 |
rat |
| M Niu, Y Ying, P A Bartell, K J Harvatin. The effects of feeding time on milk production, total-tract digestibility, and daily rhythms of feeding behavior and plasma metabolites and hormones in dairy cows. Journal of dairy science. vol 97. issue 12. 2015-08-19. PMID:25306274. |
specifically, insulin increased and glucose decreased more after evening feeding than after morning feeding. |
2015-08-19 |
2023-08-13 |
Not clear |
| M Niu, Y Ying, P A Bartell, K J Harvatin. The effects of feeding time on milk production, total-tract digestibility, and daily rhythms of feeding behavior and plasma metabolites and hormones in dairy cows. Journal of dairy science. vol 97. issue 12. 2015-08-19. PMID:25306274. |
rate of feed intake during spontaneous feeding, fecal ndf and indf concentration, plasma glucose, insulin, nefa, body temperature, and lying behavior fit a cosine function within a 24-h period that was modified by treatment. |
2015-08-19 |
2023-08-13 |
Not clear |
| M Niu, Y Ying, P A Bartell, K J Harvatin. The effects of feeding time on milk production, total-tract digestibility, and daily rhythms of feeding behavior and plasma metabolites and hormones in dairy cows. Journal of dairy science. vol 97. issue 12. 2015-08-19. PMID:25306274. |
in conclusion, feeding time can reset the daily rhythms of feeding and lying behavior, core body temperature, fecal ndf and indf concentration, and plasma blood urea nitrogen, glucose, and insulin concentration of dairy cows, but has no effect on daily dmi and milk production. |
2015-08-19 |
2023-08-13 |
Not clear |
| F Piccioli-Cappelli, J J Loor, C J Seal, A Minuti, E Trevis. Effect of dietary starch level and high rumen-undegradable protein on endocrine-metabolic status, milk yield, and milk composition in dairy cows during early and late lactation. Journal of dairy science. vol 97. issue 12. 2015-08-19. PMID:25459908. |
feeding ls versus hs resulted in an increase in the ratio of bovine somatotropin to insulin. |
2015-08-19 |
2023-08-13 |
cattle |
| Guillaume Vial, Marie-Agnès Chauvin, Nadia Bendridi, Annie Durand, Emmanuelle Meugnier, Anne-Marie Madec, Nathalie Bernoud-Hubac, Jean-Paul Pais de Barros, Éric Fontaine, Cécile Acquaviva, Sophie Hallakou-Bozec, Sébastien Bolze, Hubert Vidal, Jennifer Rieusse. Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrial function in liver of a high-fat, high-sucrose diet mice model. Diabetes. vol 64. issue 6. 2015-08-19. PMID:25552598. |
six-week imeglimin treatment significantly decreased glycemia, restored normal glucose tolerance, and improved insulin sensitivity without modifying organs, body weights, and food intake. |
2015-08-19 |
2023-08-13 |
mouse |