| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P A Rushing, M M Hagan, R J Seeley, T A Lutz, D A D'Alessio, E L Air, S C Wood. Inhibition of central amylin signaling increases food intake and body adiposity in rats. Endocrinology. vol 142. issue 11. 2001-12-04. PMID:11606473. |
amylin is a 37-amino acid peptide hormone that is co-secreted with insulin by pancreatic beta cells in response to feeding. |
2001-12-04 |
2023-08-12 |
rat |
| P R Wang, Q Guo, M Ippolito, M Wu, D Milot, J Ventre, T Doebber, S D Wright, Y S Cha. High fat fed hamster, a unique animal model for treatment of diabetic dyslipidemia with peroxisome proliferator activated receptor alpha selective agonists. European journal of pharmacology. vol 427. issue 3. 2001-11-01. PMID:11567659. |
ten days of high fat feeding in golden syrian hamsters resulted in a significant increase in insulin resistance and baseline serum lipid levels accompanied by a pronounced dyslipidemia. |
2001-11-01 |
2023-08-12 |
Not clear |
| A P Mizisin, R C Steinhardt, J S O'Brien, N A Calcut. TX14(A), a prosaposin-derived peptide, reverses established nerve disorders in streptozotocin-diabetic rats and prevents them in galactose-fed rats. Journal of neuropathology and experimental neurology. vol 60. issue 10. 2001-10-25. PMID:11589426. |
here, the efficacy of tx14(a) in reversing established nerve conduction disorders in streptozotocin diabetes, a model of insulin deficiency, and preventing them in galactose feeding, an insulin-replete model of polyol pathway flux, was investigated. |
2001-10-25 |
2023-08-12 |
rat |
| S Dagogo-Jac. Human leptin regulation and promise in pharmacotherapy. Current drug targets. vol 2. issue 2. 2001-10-18. PMID:11469718. |
in rodents leptin inhibits food intake, stimulates energy expenditure, reverses obesity, ameliorates insulin resistance, and accelerates sexual maturation. |
2001-10-18 |
2023-08-12 |
human |
| T P Mommsen, T W Moon, E M Plisetskay. Effects of arginine on pancreatic hormones and hepatic metabolism in rainbow trout. Physiological and biochemical zoology : PBZ. vol 74. issue 5. 2001-10-18. PMID:11517452. |
resulting ratios of glucagon and glp-1 over insulin are unchanged in 20-d food-deprived fish (saline, 1.28 vs. arg, 0.93; not significant) while slightly increased in feeding trout (saline, 0.70 vs. arg, 0.92; p<0.05). |
2001-10-18 |
2023-08-12 |
rabbit |
| E Rask, T Olsson, S Söderberg, O Johnson, J Seckl, J J Holst, B Ahré. Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men. Diabetes care. vol 24. issue 9. 2001-10-11. PMID:11522713. |
to investigate whether features of the insulin resistance syndrome are associated with altered incretin responses to food intake. |
2001-10-11 |
2023-08-12 |
Not clear |
| S Verma, Y M Leung, L Yao, M Battell, A S Dumont, J H McNeil. Hyperinsulinemia superimposed on insulin resistance does not elevate blood pressure. American journal of hypertension. vol 14. issue 5 Pt 1. 2001-10-04. PMID:11368463. |
to examine this proposition, we studied the effects of chronic fructose feeding on plasma insulin levels and bp in insulin-resistant zucker fatty rats and in lean (insulin-sensitive) controls. |
2001-10-04 |
2023-08-12 |
rat |
| S Verma, Y M Leung, L Yao, M Battell, A S Dumont, J H McNeil. Hyperinsulinemia superimposed on insulin resistance does not elevate blood pressure. American journal of hypertension. vol 14. issue 5 Pt 1. 2001-10-04. PMID:11368463. |
long term fructose feeding increased plasma insulin levels and bp in the lean group. |
2001-10-04 |
2023-08-12 |
rat |
| J Ukropec, E Seböková, I Klime. Nutrient sensing, leptin and insulin action. Archives of physiology and biochemistry. vol 109. issue 1. 2001-10-04. PMID:11471070. |
in this article, the proposed lipopenic effects of leptin as studied in various animal models of diet-induced insulin resistance, and possible regulations of leptin production and action by marine fish oil feeding are reviewed. |
2001-10-04 |
2023-08-12 |
Not clear |
| W Langhans, F Grossmann, N Gear. Intrameal hepatic-portal infusion of glucose reduces spontaneous meal size in rats. Physiology & behavior. vol 73. issue 4. 2001-10-04. PMID:11495653. |
to test whether glucose (glc) or insulin (ins) acutely reduces spontaneous meal size, we tested the effects of remotely controlled, intrameal hepatic-portal vein infusions of glc or ins on rats' spontaneous feeding patterns. |
2001-10-04 |
2023-08-12 |
rat |
| O Schmidt, E Deegen, H Fuhrmann, R Dühlmeier, H P Sallman. Effects of fat feeding and energy level on plasma metabolites and hormones in Shetland ponies. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. vol 48. issue 1. 2001-10-04. PMID:11515311. |
oral glucose administration after feeding the hypercaloric fat-enriched diet led to a 25-fold increase of plasma insulin levels. |
2001-10-04 |
2023-08-12 |
Not clear |
| S E Borst, H G Snelle. Metformin, but not exercise training, increases insulin responsiveness in skeletal muscle of Sprague-Dawley rats. Life sciences. vol 69. issue 13. 2001-10-04. PMID:11554611. |
metformin, training, and pair-feeding all decreased food intake, body weight, and insulin concentration following glucose loading. |
2001-10-04 |
2023-08-12 |
rat |
| S E Borst, H G Snelle. Metformin, but not exercise training, increases insulin responsiveness in skeletal muscle of Sprague-Dawley rats. Life sciences. vol 69. issue 13. 2001-10-04. PMID:11554611. |
we conclude that metformin reverses the maturation-induced impairment of insulin responsiveness in sprague-dawley rats by increasing insulin-stimulated glucose transport in skeletal muscle and that this effect is not secondary to reduced food intake. |
2001-10-04 |
2023-08-12 |
rat |
| A M McKillop, M H Mooney, P Harriott, P R Flatt, F P O'Hart. Evaluation of glycated insulin in diabetic animals using immunocytochemistry and radioimmunoassay. Biochemical and biophysical research communications. vol 286. issue 3. 2001-09-27. PMID:11511090. |
following a 30 min feeding period in these insulin resistant rats, plasma glucose, insulin, and glycated insulin increased (p < 0.001) rapidly with 1.4-, 1.6-, and 2.9-fold elevations, respectively. |
2001-09-27 |
2023-08-12 |
mouse |
| K Filipsson, M Kvist-Reimer, B Ahré. The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function. Diabetes. vol 50. issue 9. 2001-09-20. PMID:11522660. |
accumulating evidence in animal studies points to a physiological importance of pacap in the regulation of the insulin response to feeding. |
2001-09-20 |
2023-08-12 |
Not clear |
| D S Bel. Importance of postprandial glucose control. Southern medical journal. vol 94. issue 8. 2001-09-20. PMID:11549192. |
early in the development of type 2 diabetes, the initial burst of insulin release in response to food intake is compromised, allowing postprandial hyperglycemia to develop. |
2001-09-20 |
2023-08-12 |
Not clear |
| A Elkayam, D Mirelman, E Peleg, M Wilchek, T Miron, A Rabinkov, S Sadetzki, T Rosentha. The effects of allicin and enalapril in fructose-induced hyperinsulinemic hyperlipidemic hypertensive rats. American journal of hypertension. vol 14. issue 4 Pt 1. 2001-09-13. PMID:11336185. |
the effects of a synthetic preparation of an active constituent of garlic, allicin, were studied on blood pressure (bp), triglycerides, and insulin levels in sprague-dawley rats in which high fructose feeding elicited hyperinsulinemia, hypertension, and hypertriglyceridemia. |
2001-09-13 |
2023-08-12 |
rat |
| M H Vickers, B A Ikenasio, B H Breie. IGF-I treatment reduces hyperphagia, obesity, and hypertension in metabolic disorders induced by fetal programming. Endocrinology. vol 142. issue 9. 2001-09-13. PMID:11517175. |
however, systolic blood pressure, food intake, retroperitoneal and gonadal fat pad weights, and plasma leptin and insulin concentrations were markedly reduced with igf-i treatment. |
2001-09-13 |
2023-08-12 |
human |
| T G Anthony, A K Reiter, J C Anthony, S R Kimball, L S Jefferso. Deficiency of dietary EAA preferentially inhibits mRNA translation of ribosomal proteins in liver of meal-fed rats. American journal of physiology. Endocrinology and metabolism. vol 281. issue 3. 2001-09-06. PMID:11500297. |
in the experiments conducted, male weanling rats were trained over a 2-wk period to consume their daily food intake within 3 h. on day 14, rats were fed the control diet or an isocaloric, isonitrogenous diet lacking glycine, tryptophan, leucine, or the branched-chain amino acids (bcaa) for 1 h. feeding trp-, leu-, or bcaa-deficient diets resulted in significant reductions in serum insulin, hepatic protein synthesis, eukaryotic initiation factor 2b (eif2b) activity, and phosphorylation of eif4e-binding protein 1 (4e-bp1) and ribosomal protein s6 kinase (s6k1). |
2001-09-06 |
2023-08-12 |
rat |
| M Balage, S Sinaud, M Prod'homme, D Dardevet, T C Vary, S R Kimball, L S Jefferson, J Grizar. Amino acids and insulin are both required to regulate assembly of the eIF4E. eIF4G complex in rat skeletal muscle. American journal of physiology. Endocrinology and metabolism. vol 281. issue 3. 2001-09-06. PMID:11500312. |
the respective roles of insulin and amino acids in regulation of skeletal muscle protein synthesis and degradation after feeding were examined in rats fasted for 17 h and refed over 1 h with either a 25 or a 0% amino acid/protein meal. |
2001-09-06 |
2023-08-12 |
rat |