| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| U N Da. Is obesity an inflammatory condition? Nutrition (Burbank, Los Angeles County, Calif.). vol 17. issue 11-12. 2002-04-26. PMID:11744348. |
acetylcholine and insulin inhibit the production of proinflammatory cytokines and provide a negative feedback loop for postprandial inhibition of food intake, in part, by regulating leptin action. |
2002-04-26 |
2023-08-12 |
Not clear |
| Adil El Midaoui, Jacques de Champlai. Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid. Hypertension (Dallas, Tex. : 1979). vol 39. issue 2. 2002-04-25. PMID:11847202. |
these findings demonstrate that high-glucose feeding rapidly induced hypertension and insulin resistance in association with the induction of a vascular oxidative stress. |
2002-04-25 |
2023-08-12 |
rat |
| A Caixás, C Bashore, W Nash, F Pi-Sunyer, B Laferrèr. Insulin, unlike food intake, does not suppress ghrelin in human subjects. The Journal of clinical endocrinology and metabolism. vol 87. issue 4. 2002-04-25. PMID:11932338. |
insulin, unlike food intake, does not suppress ghrelin in human subjects. |
2002-04-25 |
2023-08-12 |
human |
| Asako Minami, Noriko Ishimura, Sadaichi Sakamoto, Eiko Takishita, Kazuaki Mawatari, Kazuko Okada, Yutaka Nakay. Effect of eicosapentaenoic acid ethyl ester v. oleic acid-rich safflower oil on insulin resistance in type 2 diabetic model rats with hypertriacylglycerolaemia. The British journal of nutrition. vol 87. issue 2. 2002-04-22. PMID:11895168. |
the results indicate that long-term feeding of epa might be effective in preventing insulin resistance in diabetes-prone rats, at least in part, due to improving hypertriacylglycerolaemia. |
2002-04-22 |
2023-08-12 |
rat |
| Leonardo Paiva, Ralf Binsack, Ubiratan Fabres Machad. Chronic acarbose-feeding increases GLUT1 protein without changing intestinal glucose absorption function. European journal of pharmacology. vol 434. issue 3. 2002-04-18. PMID:11779583. |
while food intake was slightly enhanced by acarbose, the drug had no influence on weight gain or plasma glucose and insulin levels. |
2002-04-18 |
2023-08-12 |
rat |
| A V Abramov, Iu M Kolesni. [Morphofunctional characteristics of gastrin-releasing peptide synthesizing system of the hypothalamus in normal conditions and in experimental diabetes in rats]. Morfologiia (Saint Petersburg, Russia). vol 120. issue 5. 2002-04-18. PMID:11878232. |
thus, the increase of grp synthesis in hypothalamic neurosecretory structures in diabetes mellitus may be considered as a compensatory reaction directed on the activation of the central mechanisms of feeding restriction and stimulation of insulin synthesis in the pancreas. |
2002-04-18 |
2023-08-12 |
rat |
| R J Shulma. Effect of enteral administration of insulin on intestinal development and feeding tolerance in preterm infants: a pilot study. Archives of disease in childhood. Fetal and neonatal edition. vol 86. issue 2. 2002-04-18. PMID:11882558. |
effect of enteral administration of insulin on intestinal development and feeding tolerance in preterm infants: a pilot study. |
2002-04-18 |
2023-08-12 |
Not clear |
| Anne Jörns, Markus Tiedge, Ehud Ziv, Eleazar Shafrir, Sigurd Lenze. Gradual loss of pancreatic beta-cell insulin, glucokinase and GLUT2 glucose transporter immunoreactivities during the time course of nutritionally induced type-2 diabetes in Psammomys obesus (sand rat). Virchows Archiv : an international journal of pathology. vol 440. issue 1. 2002-04-18. PMID:11942578. |
the reduction of the total beta-cell volume of the pancreas due to beta-cell death and the diminution of insulin content of the remaining beta cells in the islets during the he diet feeding was accompanied by a parallel fall of the pancreas insulin content. |
2002-04-18 |
2023-08-12 |
rat |
| Michelle Z Tucker, Lorraine P Turcott. Brief food restriction increases FA oxidation and glycogen synthesis under insulin-stimulated conditions. American journal of physiology. Regulatory, integrative and comparative physiology. vol 282. issue 4. 2002-04-16. PMID:11893627. |
to determine the effects of brief food restriction on fatty acid (fa) metabolism, hindlimbs of f344/bn rats fed either ad libitum (al) or food restricted (fr) to 60% of baseline food intake for 28 days were perfused under hyperglycemic-hyperinsulinemic conditions (20 mm glucose, 1 mm palmitate, 1,000 microu/ml insulin, [3-(3)h]glucose, and [1-(14)c]palmitate). |
2002-04-16 |
2023-08-12 |
rat |
| Eduard Jose-Cunilleras, Kenneth W Hinchcliff, Richard A Sams, Steven T Devor, Jon K Linderma. Glycemic index of a meal fed before exercise alters substrate use and glucose flux in exercising horses. Journal of applied physiology (Bethesda, Md. : 1985). vol 92. issue 1. 2002-04-10. PMID:11744650. |
feeding corn, compared with fasting, resulted in higher plasma glucose and serum insulin and lower serum nonesterified fatty acid concentrations before exercise (p < 0.05) and in lower plasma glucose, serum glycerol, and serum nonesterified fatty acid concentrations and higher skeletal muscle utilization of blood-borne glucose during exercise (p < 0.05). |
2002-04-10 |
2023-08-12 |
Not clear |
| Teresa A Davis, Marta L Fiorotto, Douglas G Burrin, Peter J Reeds, Hanh V Nguyen, Philip R Beckett, Rhonda C Vann, Pamela M J O'Conno. Stimulation of protein synthesis by both insulin and amino acids is unique to skeletal muscle in neonatal pigs. American journal of physiology. Endocrinology and metabolism. vol 282. issue 4. 2002-04-08. PMID:11882508. |
the results suggest that, in the neonate, the stimulation of protein synthesis by feeding is mediated by either amino acids or insulin in most tissues; however, the feeding-induced stimulation of protein synthesis in skeletal muscle is uniquely regulated by both insulin and amino acids. |
2002-04-08 |
2023-08-12 |
Not clear |
| S C Woods, R J Seele. Insulin as an adiposity signal. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 25 Suppl 5. 2002-04-05. PMID:11840212. |
experimental manipulation of brain insulin causes predictable changes of food intake and body weight. |
2002-04-05 |
2023-08-12 |
Not clear |
| M Tang-Christensen, N Vrang, P J Larse. Glucagon-like peptide containing pathways in the regulation of feeding behaviour. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 25 Suppl 5. 2002-04-05. PMID:11840214. |
the pre-proglucagon derived peptides, glucagon-like peptide-1 (glp-1) and glucagon-like peptide-2 (glp-2) are both involved in a wide variety of peripheral functions, such as glucose homeostasis, gastric emptying, intestinal growth, insulin secretion as well as the regulation of food intake. |
2002-04-05 |
2023-08-12 |
rat |
| G J Morton, M W Schwart. The NPY/AgRP neuron and energy homeostasis. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 25 Suppl 5. 2002-04-05. PMID:11840217. |
recent studies implicate leptin and insulin as 'adiposity signals' to the brain that promote negative energy balance in two ways: by inhibiting 'anabolic' hypothalamic neuronal circuits that stimulate food intake and promote weight gain, and by activating 'catabolic' pathways that reduce food intake and body weight. |
2002-04-05 |
2023-08-12 |
Not clear |
| Shuji Hidaka, Hironobu Yoshimatsu, Seiya Kondou, Yoshio Tsuruta, Kyoko Oka, Hitoshi Noguchi, Kenjirou Okamoto, Hiroshi Sakino, Yasushi Teshima, Toshimitsu Okeda, Toshiie Sakat. Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 6. 2002-04-05. PMID:11919153. |
chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats. |
2002-04-05 |
2023-08-12 |
rat |
| Shuji Hidaka, Hironobu Yoshimatsu, Seiya Kondou, Yoshio Tsuruta, Kyoko Oka, Hitoshi Noguchi, Kenjirou Okamoto, Hiroshi Sakino, Yasushi Teshima, Toshimitsu Okeda, Toshiie Sakat. Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 6. 2002-04-05. PMID:11919153. |
we conclude that centrally infused leptin does not control serum glucose by regulating feeding volume or elevating peripheral insulin, but by regulating hepatic glucose production, peripheral glucose uptake, and energy expenditure. |
2002-04-05 |
2023-08-12 |
rat |
| P Anurag, C V Anuradh. Metformin improves lipid metabolism and attenuates lipid peroxidation in high fructose-fed rats. Diabetes, obesity & metabolism. vol 4. issue 1. 2002-04-03. PMID:11874440. |
insulin resistance, hyperinsulinaemia and disturbances in glucose metabolism can be produced in normal rats by feeding them a fructose-enriched diet. |
2002-04-03 |
2023-08-12 |
rat |
| G J Martin, J S Ran. Food intake and blood glucose in normal and diabetic cats fed ad libitum. Journal of feline medicine and surgery. vol 1. issue 4. 2002-03-28. PMID:11714241. |
the food intake and blood glucose were measured every 2 h in diabetic cats after insulin injection and in diabetic and normal cats without insulin injections. |
2002-03-28 |
2023-08-12 |
cat |
| E Naruta, V Buk. Hypolipidemic effect of pantothenic acid derivatives in mice with hypothalamic obesity induced by aurothioglucose. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 53. issue 5. 2002-03-28. PMID:11817109. |
the treatment with aurothioglucose increased food intake and mean body weight, blood glucose level; insulin, serum total cholesterol, triglyceride, the sum of ldl + vldl and ldl-cholesterol concentration; triglyceride and cholesterol fractions in the liver; triglyceride and ffa content as well as lipoprotein lipase activity in adipose tissue of experimental mice. |
2002-03-28 |
2023-08-12 |
mouse |
| E Naruta, V Buk. Hypolipidemic effect of pantothenic acid derivatives in mice with hypothalamic obesity induced by aurothioglucose. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 53. issue 5. 2002-03-28. PMID:11817109. |
the administration of the assay compounds lowered food intake and mean body weight, insulin and glucose levels and decreased the content of triglycerides, total cholesterol and cholesterol esters in serum and adipose tissue as well as raised the activity of lipoprotein lipase in adipose tissue and serum lipolytic activity in obese mice. |
2002-03-28 |
2023-08-12 |
mouse |