| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Christine Könner, Ruth Janoschek, Leona Plum, Sabine D Jordan, Eva Rother, Xiaosong Ma, Chun Xu, Pablo Enriori, Brigitte Hampel, Gregory S Barsh, C Ronald Kahn, Michael A Cowley, Frances M Ashcroft, Jens C Brünin. Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production. Cell metabolism. vol 5. issue 6. 2008-07-03. PMID:17550779. |
these results directly demonstrate that insulin action in pomc and agrp cells is not required for steady-state regulation of food intake and body weight. |
2008-07-03 |
2023-08-12 |
mouse |
| Teruo Kawada, Tsuyoshi Goto, Shizuka Hirai, Min-Sook Kang, Taku Uemura, Rina Yu, Nobuyuki Takahash. Dietary regulation of nuclear receptors in obesity-related metabolic syndrome. Asia Pacific journal of clinical nutrition. vol 17 Suppl 1. 2008-07-02. PMID:18296319. |
however, more than 10 years of research has shown that adipocytes also function as endocrine cells that release various bioactive substances, so called "adipocytokines or adipokines", that play a major role in the regulation of food intake, insulin sensitivity, energy metabolism, and the vascular microenvironment. |
2008-07-02 |
2023-08-12 |
Not clear |
| J Wernerman, A von der Decken, E Vinnar. The diurnal pattern of protein synthesis in human skeletal muscle. Clinical nutrition (Edinburgh, Scotland). vol 4. issue 4. 2008-06-25. PMID:16831733. |
the concentration of insulin showed peaks in response to food intake, and that of cortisol decreased over the day. |
2008-06-25 |
2023-08-12 |
human |
| Chad R Hancock, Dong-Ho Han, May Chen, Shin Terada, Toshihiro Yasuda, David C Wright, John O Hollosz. High-fat diets cause insulin resistance despite an increase in muscle mitochondria. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 22. 2008-06-24. PMID:18509063. |
in contrast, we found that feeding rats high-fat diets that cause muscle insulin resistance results in a concomitant gradual increase in muscle mitochondria. |
2008-06-24 |
2023-08-12 |
rat |
| Ralph J Manders, René Koopman, Milou Beelen, Annemie P Gijsen, Will K Wodzig, Wim H Saris, Luc J van Loo. The muscle protein synthetic response to carbohydrate and protein ingestion is not impaired in men with longstanding type 2 diabetes. The Journal of nutrition. vol 138. issue 6. 2008-06-23. PMID:18492837. |
insulin resistance has been suggested to result in a reduced muscle protein synthetic response to food intake. |
2008-06-23 |
2023-08-12 |
Not clear |
| H van Bronswijk, E A Dubois, H Pijl, A F Cohe. [New drugs; exenatide and sitagliptin]. Nederlands tijdschrift voor geneeskunde. vol 152. issue 15. 2008-06-17. PMID:18512528. |
both drugs increase the glp-i concentration, thereby improving insulin secretion from pancreatic p cells, restoring glycaemic control, preventing beta cell destruction, delaying gastric emptying, and reducing food intake. |
2008-06-17 |
2023-08-12 |
Not clear |
| Victor A Gault, Barry D Kerr, Nigel Irwin, Peter R Flat. C-terminal mini-PEGylation of glucose-dependent insulinotropic polypeptide exhibits metabolic stability and improved glucose homeostasis in dietary-induced diabetes. Biochemical pharmacology. vol 75. issue 12. 2008-06-16. PMID:18455149. |
daily administration of gip[mpeg] for 20 days in high fat mice did not alter body weight, food intake or non-fasting plasma insulin, however, non-fasting plasma glucose concentrations were significantly lowered (p < 0.05). |
2008-06-16 |
2023-08-12 |
mouse |
| Eugene F du Toit, Wayne Smith, Christo Muller, Hans Strijdom, Bernadette Stouthammer, Angela J Woodiwiss, Gavin R Norton, Amanda Lochne. Myocardial susceptibility to ischemic-reperfusion injury in a prediabetic model of dietary-induced obesity. American journal of physiology. Heart and circulatory physiology. vol 294. issue 5. 2008-06-12. PMID:18359896. |
feeding rats a high-calorie diet resulted in increases in body weight, visceral fat content, cardiac hypertrophy, plasma insulin, nonesterified free fatty acid, and triglyceride concentrations. |
2008-06-12 |
2023-08-12 |
rat |
| C W H Rumball, J E Harding, M H Oliver, F H Bloomfiel. Effects of twin pregnancy and periconceptional undernutrition on maternal metabolism, fetal growth and glucose-insulin axis function in ovine pregnancy. The Journal of physiology. vol 586. issue 5. 2008-06-05. PMID:18187465. |
we found that twin-bearing ewes had decreased maternal food intake in late gestation and lower maternal and fetal plasma glucose and insulin levels. |
2008-06-05 |
2023-08-12 |
Not clear |
| Jae-Min Lim, Dan Sherling, Chin Fen Teo, Dorothy B Hausman, Dawei Lin, Lance Well. Defining the regulated secreted proteome of rodent adipocytes upon the induction of insulin resistance. Journal of proteome research. vol 7. issue 3. 2008-06-03. PMID:18237111. |
adipocytes, besides being a major site for energy storage, are endocrine in nature and secrete a variety of proteins, adipocytokines (adipokines), that can modulate insulin sensitivity, inflammation, obesity, hypertension, food intake (anorexigenic and orexigenic), and general energy homeostasis. |
2008-06-03 |
2023-08-12 |
Not clear |
| Miriam Ryan, M Barbara E Livingstone, Pierre-Henri Ducluzeau, Agnès Sallé, Manon Genaitay, Patrick Rit. Is a failure to recognize an increase in food intake a key to understanding insulin-induced weight gain? Diabetes care. vol 31. issue 3. 2008-06-02. PMID:18086874. |
changes in energy intake (self-report and weighed food intake), dietary behavior (auto-questionnaires), resting energy expenditure (ree) (indirect calorimetry), physical activity (accelerometry), and glucosuria were monitored over the first 6 months of insulin therapy in 46 diabetic adults. |
2008-06-02 |
2023-08-12 |
Not clear |
| G D Cooper, J A Harrold, J C G Halford, A J Goudi. Chronic clozapine treatment in female rats does not induce weight gain or metabolic abnormalities but enhances adiposity: implications for animal models of antipsychotic-induced weight gain. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 2. 2008-05-30. PMID:17933447. |
instead, clozapine induced weight loss without alteration in food intake and muscle mass or changes in levels of glucose, insulin, leptin and prolactin. |
2008-05-30 |
2023-08-12 |
rat |
| Luciana P Pisani, Lila M Oyama, Allain A Bueno, Carolina Biz, Kelse T Albuquerque, Eliane B Ribeiro, Claudia M Oller do Nasciment. Hydrogenated fat intake during pregnancy and lactation modifies serum lipid profile and adipokine mRNA in 21-day-old rats. Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 3. 2008-05-27. PMID:18178060. |
we examined whether feeding pregnant and lactating rats hydrogenated fats rich in trans-fatty acids modifies the plasma lipid profiles and the expression of adipokines involved with insulin resistance and cardiovascular disease in their 21-d-old offspring. |
2008-05-27 |
2023-08-12 |
rat |
| Luciana P Pisani, Claudia M Oller do Nascimento, Allain A Bueno, Carolina Biz, Kelse T Albuquerque, Eliane B Ribeiro, Lila M Oyam. Hydrogenated fat diet intake during pregnancy and lactation modifies the PAI-1 gene expression in white adipose tissue of offspring in adult life. Lipids in health and disease. vol 7. 2008-05-27. PMID:18394153. |
we examine whether feeding pregnant and lactating rats hydrogenated fats rich in trans fatty acids modifies the plasma lipid profiles and the expression of adipokines involved with insulin resistance and cardiovascular disease in their 90-day-old offspring. |
2008-05-27 |
2023-08-12 |
rat |
| Jesus A Gutierrez, Patricia J Solenberg, Douglas R Perkins, Jill A Willency, Michael D Knierman, Zhaoyan Jin, Derrick R Witcher, Shuang Luo, Jude E Onyia, John E Hal. Ghrelin octanoylation mediated by an orphan lipid transferase. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 17. 2008-05-22. PMID:18443287. |
this modification is crucial for ghrelin's physiological effects including regulation of feeding, adiposity, and insulin secretion. |
2008-05-22 |
2023-08-12 |
mouse |
| Jun-Ichi Shiraishi, Kouichi Yanagita, Masanori Fujita, Takashi Bung. Central insulin suppresses feeding behavior via melanocortins in chicks. Domestic animal endocrinology. vol 34. issue 3. 2008-05-19. PMID:17629654. |
central insulin suppresses feeding behavior via melanocortins in chicks. |
2008-05-19 |
2023-08-12 |
Not clear |
| Jun-Ichi Shiraishi, Kouichi Yanagita, Masanori Fujita, Takashi Bung. Central insulin suppresses feeding behavior via melanocortins in chicks. Domestic animal endocrinology. vol 34. issue 3. 2008-05-19. PMID:17629654. |
growing evidence suggests that insulin interacts with both orexigenic and anorexigenic peptides in the brain for the control of feeding behavior in mammals. |
2008-05-19 |
2023-08-12 |
Not clear |
| Jun-Ichi Shiraishi, Kouichi Yanagita, Masanori Fujita, Takashi Bung. Central insulin suppresses feeding behavior via melanocortins in chicks. Domestic animal endocrinology. vol 34. issue 3. 2008-05-19. PMID:17629654. |
in the present study, we investigated the effects of central injection of insulin on feeding behavior in chicks. |
2008-05-19 |
2023-08-12 |
Not clear |
| Jun-Ichi Shiraishi, Kouichi Yanagita, Masanori Fujita, Takashi Bung. Central insulin suppresses feeding behavior via melanocortins in chicks. Domestic animal endocrinology. vol 34. issue 3. 2008-05-19. PMID:17629654. |
intracerebroventricular (icv) administration of insulin, at doses that do not influence peripheral glucose levels, significantly inhibited food intake in chicks. |
2008-05-19 |
2023-08-12 |
Not clear |
| Jun-Ichi Shiraishi, Kouichi Yanagita, Masanori Fujita, Takashi Bung. Central insulin suppresses feeding behavior via melanocortins in chicks. Domestic animal endocrinology. vol 34. issue 3. 2008-05-19. PMID:17629654. |
finally, co-injection of the melanocortin antagonist (shu9119 or hs014) prevented the reduction in food intake caused by icv administration of insulin. |
2008-05-19 |
2023-08-12 |
Not clear |