| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naoto Kubota, Tetsuya Kubota, Shinsuke Itoh, Hiroki Kumagai, Hideki Kozono, Iseki Takamoto, Tomoka Mineyama, Hitomi Ogata, Kumpei Tokuyama, Mitsuru Ohsugi, Takayoshi Sasako, Masao Moroi, Kaoru Sugi, Shigeru Kakuta, Yoichiro Iwakura, Tetsuo Noda, Shin Ohnishi, Ryozo Nagai, Kazuyuki Tobe, Yasuo Terauchi, Kohjiro Ueki, Takashi Kadowak. Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding. Cell metabolism. vol 8. issue 1. 2008-08-21. PMID:18590692. |
we propose the concept of the existence of a dynamic relay between irs1 and irs2 in hepatic insulin signaling during fasting and feeding. |
2008-08-21 |
2023-08-12 |
mouse |
| Xiaocheng C Dong, Kyle D Copps, Shaodong Guo, Yedan Li, Ramya Kollipara, Ronald A DePinho, Morris F Whit. Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell metabolism. vol 8. issue 1. 2008-08-21. PMID:18590693. |
liver-specific deletion of foxo1 in dko mice resulted in significant normalization of the dko-liver transcriptome and partial restoration of the response to fasting and feeding, near normal blood glucose and insulin concentrations, and normalization of body size. |
2008-08-21 |
2023-08-12 |
mouse |
| J-F Gautier, S-P Choukem, J Girar. Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes. Diabetes & metabolism. vol 34 Suppl 2. 2008-08-19. PMID:18640588. |
in addition to its effects on insulin secretion, glp-1 exerts other significant actions, including stimulation of insulin biosynthesis, inhibition of glucagon secretion, inhibition of gastric emptying and acid secretion, reduction of food intake, and trophic effects on the pancreas. |
2008-08-19 |
2023-08-12 |
Not clear |
| Matthew C Althage, Eric L Ford, Songyan Wang, Patrick Tso, Kenneth S Polonsky, Burton M Wic. Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet. The Journal of biological chemistry. vol 283. issue 26. 2008-08-18. PMID:18420580. |
food intake, body weight, and blood glucose levels in response to insulin or intraperitoneal glucose were similar in control and gip/dt mice fed standard chow. |
2008-08-18 |
2023-08-12 |
mouse |
| Matthew C Althage, Eric L Ford, Songyan Wang, Patrick Tso, Kenneth S Polonsky, Burton M Wic. Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet. The Journal of biological chemistry. vol 283. issue 26. 2008-08-18. PMID:18420580. |
transgenic versus wild-type mice demonstrated significantly reduced body weight (25%), plasma leptin levels (77%), and daily food intake (16%) plus enhanced energy expenditure (10%) and insulin sensitivity. |
2008-08-18 |
2023-08-12 |
mouse |
| Vivien Gattás, Gladys Barrera, Laura Leiva, M Pía de la Maza, Daniel Bunout, Philippe Steenhout, Petra Klassen, Theresa Voss, Sandra Hirsc. [Glycemic and insulin indices of tube feeding formulas in healthy adults]. Revista medica de Chile. vol 135. issue 7. 2008-08-07. PMID:17914545. |
[glycemic and insulin indices of tube feeding formulas in healthy adults]. |
2008-08-07 |
2023-08-12 |
Not clear |
| Yongho Lee, Mi Kyong Kwon, Eun Seok Kang, Young Mi Park, Seung Ho Choi, Chul Woo Ahn, Kyung Sub Kim, Chul Won Park, Bong Soo Cha, Sung Wan Kim, Je Kyung Sung, Eun Jig Lee, Hyun Chul Le. Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats. The journal of gene medicine. vol 10. issue 3. 2008-08-07. PMID:18085721. |
its functions include glucose-stimulated insulin secretion, suppression of glucagon secretion, deceleration of gastric emptying, and reduction in appetite and food intake. |
2008-08-07 |
2023-08-12 |
rat |
| Jun Lian, Xiang-Hua Yan, Jian Peng, Si-Wen Jian. The mammalian target of rapamycin pathway and its role in molecular nutrition regulation. Molecular nutrition & food research. vol 52. issue 4. 2008-08-06. PMID:18306429. |
in this report, we review the mtor signaling pathway and its interaction with food intake, insulin resistance, lifespan and adipogenic regulation during the molecular nutrition regulation. |
2008-08-06 |
2023-08-12 |
Not clear |
| Mitsugu Yamanaka, Yasushi Itakura, Michiko Ono-Kishino, Atsushi Tsuchida, Tsutomu Nakagawa, Mutsuo Taij. Intermittent administration of brain-derived neurotrophic factor (BDNF) ameliorates glucose metabolism and prevents pancreatic exhaustion in diabetic mice. Journal of bioscience and bioengineering. vol 105. issue 4. 2008-08-05. PMID:18499057. |
lastly, because bdnf reduces the food intake of obese hyperphagic diabetic mice, the effects of bdnf administered once or twice a week on the blood glucose concentration and plasma and pancreatic insulin concentrations in db/db mice were compared with those of the vehicle under pair-fed conditions. |
2008-08-05 |
2023-08-12 |
mouse |
| M J Morris, H Chen, R Watts, A Shulkes, D Cameron-Smit. Brain neuropeptide Y and CCK and peripheral adipokine receptors: temporal response in obesity induced by palatable diet. International journal of obesity (2005). vol 32. issue 2. 2008-08-04. PMID:17768423. |
neuropeptide y (npy) and cholecystokinin play critical roles in the regulation of food intake and energy homeostasis, while adiponectin and carnitine palmitoyltransferase (cpt) are important for insulin sensitivity and fatty acid oxidation. |
2008-08-04 |
2023-08-12 |
Not clear |
| M Hallschmid, C Benedict, B Schultes, J Born, W Ker. Obese men respond to cognitive but not to catabolic brain insulin signaling. International journal of obesity (2005). vol 32. issue 2. 2008-08-04. PMID:17848936. |
insulin acts in the brain to reduce food intake and body weight and is considered a major adiposity signal in energy homeostasis. |
2008-08-04 |
2023-08-12 |
Not clear |
| Dinesh Gautam, Jongrye Jeon, Jian Hua Li, Sung-Jun Han, Fadi F Hamdan, Yinghong Cui, Huiyan Lu, Chuxia Deng, Oksana Gavrilova, Jürgen Wes. Metabolic roles of the M3 muscarinic acetylcholine receptor studied with M3 receptor mutant mice: a review. Journal of receptor and signal transduction research. vol 28. issue 1-2. 2008-08-01. PMID:18437633. |
under all experimental conditions tested, m(3) receptor-deficient mice showed greatly ameliorated impairments in glucose homeostasis and insulin sensitivity, reduced food intake, and a significant elevation in basal and total energy expenditure, most likely due to increased central sympathetic outflow and increased rate of fatty acid oxidation. |
2008-08-01 |
2023-08-12 |
mouse |
| Rita S Patarrão, W Wayne Lautt, Maria P Guarino, Ricardo A Afonso, Rogério T Ribeiro, Ana B Fernandes, José M Boavida, Maria Paula Maced. A new technique to assess insulin sensitivity in humans: the rapid insulin sensitivity test (RIST). Proceedings of the Western Pharmacology Society. vol 50. 2008-07-31. PMID:18605244. |
bolus (50mu/kg bw administered over 30 seconds) of insulin, before and after feeding a standardized test meal, in healthy male subjects (aged 27.8 +/- 2.4 years, bmi 23.5 +/- 1.2 kg/m2). |
2008-07-31 |
2023-08-12 |
human |
| Kimberly K Trout, Lisa Basel-Brown, Michael R Rickels, Mark H Schutta, Maja Petrova, Ellen W Freeman, Nancy C Tkacs, Karen L Tef. Insulin sensitivity, food intake, and cravings with premenstrual syndrome: a pilot study. Journal of women's health (2002). vol 17. issue 4. 2008-07-25. PMID:18447765. |
insulin sensitivity, food intake, and cravings with premenstrual syndrome: a pilot study. |
2008-07-25 |
2023-08-12 |
Not clear |
| Kimberly K Trout, Lisa Basel-Brown, Michael R Rickels, Mark H Schutta, Maja Petrova, Ellen W Freeman, Nancy C Tkacs, Karen L Tef. Insulin sensitivity, food intake, and cravings with premenstrual syndrome: a pilot study. Journal of women's health (2002). vol 17. issue 4. 2008-07-25. PMID:18447765. |
the objective of this pilot study was to evaluate possible differences in insulin sensitivity, food intake, and cravings between the follicular and luteal phases of the menstrual cycle in women with premenstrual syndrome (pms). |
2008-07-25 |
2023-08-12 |
Not clear |
| Erik J Henriksen, Mary K Teachey, Katherine A Lindborg, Cody J Diehl, Alan N Benez. The high-fat-fed lean Zucker rat: a spontaneous isocaloric model of fat-induced insulin resistance associated with muscle GSK-3 overactivity. American journal of physiology. Regulatory, integrative and comparative physiology. vol 294. issue 6. 2008-07-22. PMID:18385470. |
high-fat feeding (hff) is a well-accepted model for nutritionally-induced insulin resistance. |
2008-07-22 |
2023-08-12 |
rat |
| D Stevanović, D Nesić, V Milosević, V Starcević, W B Sever. Consummatory behavior and metabolic indicators after central ghrelin injections in rats. Regulatory peptides. vol 147. issue 1-3. 2008-07-21. PMID:18280592. |
variables measured were: food intake (fi), water intake (wi), fecal mass, urine volume, body weight (bw), retroperitoneal (rp) and epididymal (epi) white adipose tissue (wat), and changes in serum leptin, insulin, triglycerides, cholesterol, and glucose. |
2008-07-21 |
2023-08-12 |
rat |
| Jane F Fearnside, Marc-Emmanuel Dumas, Alice R Rothwell, Steven P Wilder, Olivier Cloarec, Ayo Toye, Christine Blancher, Elaine Holmes, Roger Tatoud, Richard H Barton, James Scott, Jeremy K Nicholson, Dominique Gauguie. Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PloS one. vol 3. issue 2. 2008-07-15. PMID:18301746. |
dietary changes including high fat diet (hfd) feeding promotes insulin resistance in rodent models which present useful systems for studying interactions between genetic background and environmental influences contributing to disease susceptibility and progression. |
2008-07-15 |
2023-08-12 |
mouse |
| Jane F Fearnside, Marc-Emmanuel Dumas, Alice R Rothwell, Steven P Wilder, Olivier Cloarec, Ayo Toye, Christine Blancher, Elaine Holmes, Roger Tatoud, Richard H Barton, James Scott, Jeremy K Nicholson, Dominique Gauguie. Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PloS one. vol 3. issue 2. 2008-07-15. PMID:18301746. |
our results support the concept of genomic clustering of functionally related genes and provide important information for defining biological markers predicting spontaneous susceptibility to insulin resistance and pathological adaptations to fat feeding. |
2008-07-15 |
2023-08-12 |
mouse |
| Andressa Coope, Marciane Milanski, Eliana P Araújo, Marcos Tambascia, Mário J A Saad, Bruno Geloneze, Lício A Vellos. AdipoR1 mediates the anorexigenic and insulin/leptin-like actions of adiponectin in the hypothalamus. FEBS letters. vol 582. issue 10. 2008-07-09. PMID:18394428. |
thus, adiponectin acts in the hypothalamus, activating elements of the canonical insulin and leptin signaling pathways and promoting reduction of food intake. |
2008-07-09 |
2023-08-12 |
Not clear |