| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alaric Falcon, Holger Doege, Amy Fluitt, Bernice Tsang, Nicki Watson, Mark A Kay, Andreas Stah. FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase. American journal of physiology. Endocrinology and metabolism. vol 299. issue 3. 2010-10-06. PMID:20530735. |
adeno-associated virus 8-based short hairpin rna expression vectors were used to achieve liver-specific fatp2 knockdown, which significantly reduced hepatosteatosis in the face of continued high-fat feeding, concomitant with improvements in liver physiology, fasting glucose, and insulin levels. |
2010-10-06 |
2023-08-12 |
mouse |
| Thekkethil P Nedungadi, Deborah J Cleg. Sexual dimorphism in body fat distribution and risk for cardiovascular diseases. Journal of cardiovascular translational research. vol 2. issue 3. 2010-10-04. PMID:20560019. |
peripheral metabolic signals like leptin and insulin are involved in the food intake, body weight, body fat distribution, and cardiovascular disease. |
2010-10-04 |
2023-08-12 |
Not clear |
| Joshua P Thaler, Michael W Schwart. Minireview: Inflammation and obesity pathogenesis: the hypothalamus heats up. Endocrinology. vol 151. issue 9. 2010-10-04. PMID:20573720. |
obesity induced by high-fat (hf) feeding is associated with low-grade inflammation in peripheral tissues that predisposes to insulin resistance. |
2010-10-04 |
2023-08-12 |
Not clear |
| Martin J Ronis, Jamie Badeaux, Ying Chen, Thomas M Badge. Rice protein isolate improves lipid and glucose homeostasis in rats fed high fat/high cholesterol diets. Experimental biology and medicine (Maywood, N.J.). vol 235. issue 9. 2010-09-29. PMID:20667909. |
increased liver triglyceride content, hypercholesterolemia and insulin resistance in the 'western' diet-fed rats were partially prevented by feeding rpi (p < 0.05). |
2010-09-29 |
2023-08-12 |
rat |
| Jan Gunst, Greet Van den Bergh. Blood glucose control in the intensive care unit: benefits and risks. Seminars in dialysis. vol 23. issue 2. 2010-09-28. PMID:20525106. |
this apparent contradiction may be explained by several methodological differences among studies, comprising, among others, different glucose target ranges in the control groups, different feeding policies, and variable accuracy of tools used for glucose measurement and insulin infusion. |
2010-09-28 |
2023-08-12 |
Not clear |
| Derek M Culnan, Vance Albaugh, Mingjie Sun, Christopher J Lynch, Charles H Lang, Robert N Coone. Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat. American journal of physiology. Gastrointestinal and liver physiology. vol 299. issue 3. 2010-09-24. PMID:20634437. |
changes in food intake, body weight and composition, glucose tolerance, insulin sensitivity and tissue glucose uptake, and insulin signaling as well as plasma concentrations of glucagon-like peptide-1 and glucose-dependent insulinotropic peptide were measured. |
2010-09-24 |
2023-08-12 |
rat |
| Derek M Culnan, Vance Albaugh, Mingjie Sun, Christopher J Lynch, Charles H Lang, Robert N Coone. Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat. American journal of physiology. Gastrointestinal and liver physiology. vol 299. issue 3. 2010-09-24. PMID:20634437. |
enhanced nutrient delivery to the ileum after it improves glucose tolerance, insulin sensitivity and muscle glucose uptake without altering food intake, body weight, or composition. |
2010-09-24 |
2023-08-12 |
rat |
| Vincent E de Meijer, Hau D Le, Jonathan A Meisel, Mark Pude. Repetitive orogastric gavage affects the phenotype of diet-induced obese mice. Physiology & behavior. vol 100. issue 4. 2010-09-23. PMID:20385157. |
food intake was monitored, insulin resistance determined, and steatosis was assessed by histology and quantified via magnetic resonance spectroscopy. |
2010-09-23 |
2023-08-12 |
mouse |
| Biliana Marcheva, Kathryn Moynihan Ramsey, Ethan D Buhr, Yumiko Kobayashi, Hong Su, Caroline H Ko, Ganka Ivanova, Chiaki Omura, Shelley Mo, Martha H Vitaterna, James P Lopez, Louis H Philipson, Christopher A Bradfield, Seth D Crosby, Lellean JeBailey, Xiaozhong Wang, Joseph S Takahashi, Joseph Bas. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. vol 466. issue 7306. 2010-09-21. PMID:20562852. |
during periods of feeding, pancreatic islets secrete insulin to maintain glucose homeostasis, and although rhythmic control of insulin release is recognized to be dysregulated in humans with diabetes, it is not known how the circadian clock may affect this process. |
2010-09-21 |
2023-08-12 |
mouse |
| Haruyoshi Yamaza, Toshimitsu Komatsu, Saori Wakita, Carole Kijogi, Seongjoon Park, Hiroko Hayashi, Takuya Chiba, Ryoichi Mori, Tatsuo Furuyama, Nozomu Mori, Isao Shimokaw. FoxO1 is involved in the antineoplastic effect of calorie restriction. Aging cell. vol 9. issue 3. 2010-09-20. PMID:20222901. |
aging- and cr-related changes in body weight, food intake, blood glucose, and insulin concentrations were similar between the wt and ht mice in the lifespan study. |
2010-09-20 |
2023-08-12 |
mouse |
| Irl B Hirsc. Practical pearls in insulin pump therapy. Diabetes technology & therapeutics. vol 12 Suppl 1. 2010-09-15. PMID:20515302. |
next, understanding how to react to blood glucose data and how to match prandial insulin dosing to food intake are both important. |
2010-09-15 |
2023-08-12 |
Not clear |
| April J Stull, Jose E Galgani, William D Johnson, William T Cefal. The contribution of race and diabetes status to metabolic flexibility in humans. Metabolism: clinical and experimental. vol 59. issue 9. 2010-09-13. PMID:20129629. |
factors controlling metabolic flexibility (mf), the ability of the body to switch from fat to carbohydrate oxidation in response to feeding or with insulin administration, are being actively investigated. |
2010-09-13 |
2023-08-12 |
human |
| Jennifer Pfaffly, Michael Michaelides, Gene-Jack Wang, Jeffrey E Pessin, Nora D Volkow, Panayotis K Thano. Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20175225. |
leptin decreased body weight, food intake, and plasma insulin concentration in ob/ob mice but not in wild-type mice. |
2010-09-08 |
2023-08-12 |
mouse |
| Bryan Ross, Katherine McKendy, Adel Giai. Role of urotensin II in health and disease. American journal of physiology. Regulatory, integrative and comparative physiology. vol 298. issue 5. 2010-09-08. PMID:20421634. |
it also 1) enhances foam cell formation, chemotaxis of inflammatory cells, and inotropic and hypertrophic effects on heart muscle; 2) inhibits insulin release, modulates glomerular filtration, and release of catecholamines; and 3) may help regulate food intake and the sleep cycle. |
2010-09-08 |
2023-08-12 |
Not clear |
| Kerry L Mullen, Justine M Tishinsky, Lindsay E Robinson, David J Dyc. Skeletal muscle inflammation is not responsible for the rapid impairment in adiponectin response with high-fat feeding in rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 299. issue 2. 2010-09-08. PMID:20554937. |
obesity, insulin resistance, and hyperlipidemia are recognized as low-grade inflammatory diseases; therefore, we hypothesized that high-fat feeding induces inflammation, which interferes with ad action at skeletal muscle. |
2010-09-08 |
2023-08-12 |
rat |
| Harold E Lebovit. Adjunct therapy for type 1 diabetes mellitus. Nature reviews. Endocrinology. vol 6. issue 6. 2010-09-07. PMID:20404854. |
when administered as adjunctive therapy to such patients treated with insulin, pramlintide decreases food intake and causes weight loss. |
2010-09-07 |
2023-08-12 |
Not clear |
| Jacques Philipp. [How to minimize weight gain associated with insulin treatment]. Revue medicale suisse. vol 6. issue 252. 2010-09-03. PMID:20614755. |
weight gain is in contradiction with the physiological central effect of insulin which leads to decreased food intake like leptin. |
2010-09-03 |
2023-08-12 |
Not clear |
| Meng-Jie Yang, Fang Wang, Jiang-Hua Wang, Wen-Ning Wu, Zhuang-Li Hu, Jin Cheng, Dan-Fang Yu, Li-Hong Long, Hui Fu, Na Xie, Jian-Guo Che. PI3K integrates the effects of insulin and leptin on large-conductance Ca2+-activated K+ channels in neuropeptide Y neurons of the hypothalamic arcuate nucleus. American journal of physiology. Endocrinology and metabolism. vol 298. issue 2. 2010-09-01. PMID:19671839. |
these intracellular signaling mechanisms may play key roles in regulating arc npy neuron activity and physiological processes such as the control of food intake and body weight, which are under the combined control of insulin and leptin. |
2010-09-01 |
2023-08-12 |
Not clear |
| Vicent Ribas, M T Audrey Nguyen, Darren C Henstridge, Anh-Khoi Nguyen, Simon W Beaven, Matthew J Watt, Andrea L Hevene. Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERalpha-deficient mice. American journal of physiology. Endocrinology and metabolism. vol 298. issue 2. 2010-09-01. PMID:19920214. |
although the relative glucose intolerance and insulin resistance phenotype in ko mice became more severe with high-fat feeding, wt mice were refractory to these dietary-induced effects, and this protection coincided with a marked increase in circulating adiponectin and heat shock protein 72 levels in muscle, liver, and fat. |
2010-09-01 |
2023-08-12 |
mouse |
| Vicent Ribas, M T Audrey Nguyen, Darren C Henstridge, Anh-Khoi Nguyen, Simon W Beaven, Matthew J Watt, Andrea L Hevene. Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERalpha-deficient mice. American journal of physiology. Endocrinology and metabolism. vol 298. issue 2. 2010-09-01. PMID:19920214. |
these data indicate that eralpha is critical for the maintenance of whole body insulin action and protection against tissue inflammation during both normal chow and high-fat feeding. |
2010-09-01 |
2023-08-12 |
mouse |