| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anusha P Subasinghage, Brian D Green, Peter R Flatt, Nigel Irwin, Chandralal M Hewag. Metabolic and structural properties of human obestatin {1-23} and two fragment peptides. Peptides. vol 31. issue 9. 2010-12-30. PMID:20553778. |
obestatins {1-23} and {11-23} significantly reduced food intake (86% and 90% respectively) and lowered glucose responses to feeding, whilst leaving insulin responses unchanged. |
2010-12-30 |
2023-08-12 |
mouse |
| Anil B Gaikwad, Jeena Gupta, Kulbhushan Tiko. Epigenetic changes and alteration of Fbn1 and Col3A1 gene expression under hyperglycaemic and hyperinsulinaemic conditions. The Biochemical journal. vol 432. issue 2. 2010-12-30. PMID:20836762. |
insulin resistance and type 2 diabetes in male sprague-dawley rats was developed by feeding rats an hfd (high-fat diet) and administering a low dose of stz (streptozotocin). |
2010-12-30 |
2023-08-12 |
rat |
| Ji Yeon Kim, Eun Hyun Song, Hyun Jung Lee, Yeo Kyoung Oh, Yoon Shin Park, Joo-Won Park, Bong Jo Kim, Dae Jin Kim, Inkyu Lee, Jihyun Song, Won-Ho Ki. Chronic ethanol consumption-induced pancreatic {beta}-cell dysfunction and apoptosis through glucokinase nitration and its down-regulation. The Journal of biological chemistry. vol 285. issue 48. 2010-12-30. PMID:20855893. |
here we show that chronic ethanol feeding decreases the ability of pancreatic β-cells to mediate insulin secretion and atp production in coordination with the decrease of glucokinase, glut2, and insulin expression. |
2010-12-30 |
2023-08-12 |
Not clear |
| Fabio Demontis, Norbert Perrimo. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell. vol 143. issue 5. 2010-12-30. PMID:21111239. |
moreover, foxo/4e-bp signaling in muscles decreases feeding behavior and the release of insulin from producing cells, which in turn delays the age-related accumulation of protein aggregates in other tissues. |
2010-12-30 |
2023-08-12 |
drosophila_melanogaster |
| S ThanThan, H Zhao, S Yannaing, T Ishikawa, H Kuwayam. Oxyntomodulin increases the concentrations of insulin and glucose in plasma but does not affect ghrelin secretion in Holstein cattle under normal physiological conditions. Domestic animal endocrinology. vol 39. issue 3. 2010-12-20. PMID:20705414. |
we investigated the effects of oxyntomodulin (oxm) and secretin on the secretions of ghrelin, insulin, glucagon, glucose, and nonesterified fatty acids (nefa) in pre-ruminants (5 wk old) and ruminants (10 wk old) under normal physiological (feeding) conditions. |
2010-12-20 |
2023-08-12 |
cattle |
| Andrew G Renwick, Samuel V Molinar. Sweet-taste receptors, low-energy sweeteners, glucose absorption and insulin release. The British journal of nutrition. vol 104. issue 10. 2010-12-16. PMID:20619074. |
however, data from numerous publications on the effects of low-energy sweeteners on appetite, insulin and glucose levels, food intake and body weight have shown that there is no consistent evidence that low-energy sweeteners increase appetite or subsequent food intake, cause insulin release or affect blood pressure in normal subjects. |
2010-12-16 |
2023-08-12 |
mouse |
| Mi Jin Moon, Hee Young Kim, Sin Gon Kim, Juri Park, Dong Seop Choi, Jong-Ik Hwang, Jae Young Seon. Tyr1 and Ile7 of glucose-dependent insulinotropic polypeptide (GIP) confer differential ligand selectivity toward GIP and glucagon-like peptide-1 receptors. Molecules and cells. vol 30. issue 2. 2010-12-13. PMID:20799012. |
glucagon like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are incretin hormones released in response to food intake and potentiate insulin secretion from pancreatic beta cells through their distinct yet related g protein-coupled receptors, glp1r and gipr. |
2010-12-13 |
2023-08-12 |
Not clear |
| Eduardo R Ropelle, Marcelo B Flores, Dennys E Cintra, Guilherme Z Rocha, José R Pauli, Joseane Morari, Claudio T de Souza, Juliana C Moraes, Patrícia O Prada, Dioze Guadagnini, Rodrigo M Marin, Alexandre G Oliveira, Taize M Augusto, Hernandes F Carvalho, Lício A Velloso, Mario J A Saad, José B C Carvalheir. IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition. PLoS biology. vol 8. issue 8. 2010-12-13. PMID:20808781. |
the disruption of hypothalamic-specific il-6 action blocked the beneficial effects of exercise on the re-balance of food intake and insulin and leptin resistance. |
2010-12-13 |
2023-08-12 |
mouse |
| Tomohiro Ogawa, Hideki Fujii, Katsutoshi Yoshizato, Norifumi Kawad. A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits. The American journal of pathology. vol 177. issue 1. 2010-12-06. PMID:20489159. |
after 9 months of feeding with this diet, the rabbits showed high total cholesterol levels in serum and liver tissues in the absence of insulin resistance. |
2010-12-06 |
2023-08-12 |
human |
| S C Fan, B C Yu, Z C Chen, L J Chen, H H Chung, J T Chen. The decreased expression of peroxisome proliferator-activated receptors delta (PPARdelta) is reversed by digoxin in the heart of diabetic rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 42. issue 9. 2010-12-02. PMID:20446238. |
cardiac output, heart rate, and blood pressure were markedly reduced while food intake, water intake, and blood glucose were raised in stz-rats showing lower body weight and plasma insulin as compared with the vehicle-treated controls. |
2010-12-02 |
2023-08-12 |
rat |
| J K Mills, D A Ross, M E Van Amburg. The effects of feeding medium-chain triglycerides on the growth, insulin responsiveness, and body composition of Holstein calves from birth to 85 kg of body weight. Journal of dairy science. vol 93. issue 9. 2010-11-30. PMID:20723699. |
the effects of feeding medium-chain triglycerides on the growth, insulin responsiveness, and body composition of holstein calves from birth to 85 kg of body weight. |
2010-11-30 |
2023-08-12 |
Not clear |
| J K Mills, D A Ross, M E Van Amburg. The effects of feeding medium-chain triglycerides on the growth, insulin responsiveness, and body composition of Holstein calves from birth to 85 kg of body weight. Journal of dairy science. vol 93. issue 9. 2010-11-30. PMID:20723699. |
the objective of this study was to determine the effects of feeding calves isocaloric, isonitrogenous diets that varied in the amount and type of fatty acids on growth, response to an insulin challenge, and body composition. |
2010-11-30 |
2023-08-12 |
Not clear |
| Guadalupe Sabio, Roger J Davi. cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance. Trends in biochemical sciences. vol 35. issue 9. 2010-11-24. PMID:20452774. |
feeding a high-fat diet causes activation of the jnk1 signaling pathway, insulin resistance, and obesity in mice. |
2010-11-24 |
2023-08-12 |
mouse |
| C B Reynolds, A N Elias, C S Whisnan. Effects of feeding pattern on ghrelin and insulin secretion in pigs. Domestic animal endocrinology. vol 39. issue 2. 2010-11-22. PMID:20399063. |
effects of feeding pattern on ghrelin and insulin secretion in pigs. |
2010-11-22 |
2023-08-12 |
Not clear |
| C B Reynolds, A N Elias, C S Whisnan. Effects of feeding pattern on ghrelin and insulin secretion in pigs. Domestic animal endocrinology. vol 39. issue 2. 2010-11-22. PMID:20399063. |
insulin concentrations were greater in cont pigs (p < 0.01) during most of the sampling and increased after feeding in the meal pigs (p < 0.01). |
2010-11-22 |
2023-08-12 |
Not clear |
| Ewa Pańkowska, Marlena Błazi. Bolus calculator with nutrition database software, a new concept of prandial insulin programming for pump users. Journal of diabetes science and technology. vol 4. issue 3. 2010-11-16. PMID:20513322. |
diabetics is a new software devised for patients to facilitate and improve self-managing for prandial insulin dosing and for better controlling food intake. |
2010-11-16 |
2023-08-12 |
Not clear |
| François R Jornayvaz, Michael J Jurczak, Hui-Young Lee, Andreas L Birkenfeld, David W Frederick, Dongyang Zhang, Xian-Man Zhang, Varman T Samuel, Gerald I Shulma. A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain. American journal of physiology. Endocrinology and metabolism. vol 299. issue 5. 2010-11-16. PMID:20807839. |
the aim of this study was to explore the role of kd on liver and muscle insulin sensitivity, hepatic lipid metabolism, energy expenditure, and food intake. |
2010-11-16 |
2023-08-12 |
mouse |
| Bhaskar Ponugoti, Dong-Hyun Kim, Zhen Xiao, Zachary Smith, Ji Miao, Mengwei Zang, Shwu-Yuan Wu, Cheng-Ming Chiang, Timothy D Veenstra, Jongsook Kim Kempe. SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism. The Journal of biological chemistry. vol 285. issue 44. 2010-11-16. PMID:20817729. |
acetylated srebp-1c levels were also increased in hepg2 cells treated with insulin and glucose to mimic feeding conditions, and down-regulation of p300 by sirna decreased the acetylation. |
2010-11-16 |
2023-08-12 |
mouse |
| Mark J Dekker, Qiaozhu Su, Chris Baker, Angela C Rutledge, Khosrow Adel. Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome. American journal of physiology. Endocrinology and metabolism. vol 299. issue 5. 2010-11-16. PMID:20823452. |
this review highlights recent findings in fructose feeding studies in both human and animal models with a focus on the molecular and biochemical mechanisms that underlie the development of insulin resistance, hepatic steatosis, and the metabolic syndrome. |
2010-11-16 |
2023-08-12 |
human |
| Kanta Chechi, Naomi Yasui, Katsumi Ikeda, Yukio Yamori, Sukhinder K Cheem. Flax oil-mediated activation of PPAR-γ correlates with reduction of hepatic lipid accumulation in obese spontaneously hypertensive/NDmcr-cp rats, a model of the metabolic syndrome. The British journal of nutrition. vol 104. issue 9. 2010-11-12. PMID:20546645. |
these findings suggest that flax oil feeding may activate ppar-γ-dependent pathways to alter the hepatic lipid metabolism and to increase insulin sensitivity in the obese shr/ndmcr-cp rats. |
2010-11-12 |
2023-08-12 |
rat |