| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming-Xia Cui, Jun-Feng Jiang, Rong-Liang Zheng, Rui-Lian Li, Lei Wang, Wen-Guang Li, Ming-Tang Gao, Li-Ning Yang, Jin-Yan Dou, Yong-Jie W. Therapeutic effects of a recombinant mutant of the human ciliary neurotrophic factor in a mouse model of metabolic syndrome. Die Pharmazie. vol 65. issue 4. 2010-05-26. PMID:20432625. |
pair feeding revealed the same effects as c-0.3 on obesity related indices and insulin sensitivity, but aggravated hepatic steatosis and hepatic function. |
2010-05-26 |
2023-08-12 |
mouse |
| Aleida Olivares, Juan Pablo Méndez, Elena Zambrano, Mario Cárdenas, Armando Tovar, Gerardo Perera-Marín, Alfredo Ulloa-Aguirr. Reproductive axis function and gonadotropin microheterogeneity in a male rat model of diet-induced obesity. General and comparative endocrinology. vol 166. issue 2. 2010-05-24. PMID:20005231. |
long-term (180 days), high-fat feeding rats exhibited a metabolic profile compatible with insulin resistance and metabolic syndrome; they concomitantly showed decreased intrapituitary and serum lh concentrations, low serum testosterone levels, and elevated serum 17beta-estradiol concentrations. |
2010-05-24 |
2023-08-12 |
rat |
| Yoshihisa Ohtani, Yosuke Kobayashi, Tatsuyuki Takahashi, Satoshi Haga, Mutsuo Takagi, Takanori Mashiko, Kazuo Katoh, Yoshiaki Obar. Effects of 5'-uridylic acid feeding on postprandial plasma concentrations of metabolites and metabolic hormones in pre-weaning goats. Animal science journal = Nihon chikusan Gakkaiho. vol 80. issue 5. 2010-05-20. PMID:20163622. |
analysis of blood samples taken in the morning of day 14 demonstrated that the feeding of milk replacer with ump abolished the significant changes in postprandial plasma glucose, nefa, gh and insulin concentrations induced by feeding of milk replacer alone, and demonstrated a tendency to increase igf-i levels. |
2010-05-20 |
2023-08-12 |
Not clear |
| Yoichiro Akahori, Norio Takamoto, Akio Masumoto, Seiji Inoue, Hideki Nakatsukasa, Hisashi Masuyama, Yuji Hiramats. Circulating levels of ciliary neurotrophic factor in normal pregnancy and preeclampsia. Acta medica Okayama. vol 64. issue 2. 2010-05-18. PMID:20424668. |
ciliary neurotrophic factor (cntf) has been shown to decrease food intake in mouse models of obesity and to improve insulin sensitivity. |
2010-05-18 |
2023-08-12 |
mouse |
| Uluç Yiş, Yeşim Oztürk, Ali Riza Sişman, Sezer Uysal, Ozlem Bekem Soylu, Benal Büyükgebi. The relation of serum ghrelin, leptin and insulin levels to the growth patterns and feeding characteristics in breast-fed versus formula-fed infants. The Turkish journal of pediatrics. vol 52. issue 1. 2010-05-13. PMID:20402065. |
the relation of serum ghrelin, leptin and insulin levels to the growth patterns and feeding characteristics in breast-fed versus formula-fed infants. |
2010-05-13 |
2023-08-12 |
Not clear |
| Josune Olza, María D Mesa, Concepción M Aguilera, Rosario Moreno-Torres, Africa Jiménez, Antonio Pérez de la Cruz, Angel Gi. Influence of an eicosapentaenoic and docosahexaenoic acid-enriched enteral nutrition formula on plasma fatty acid composition and biomarkers of insulin resistance in the elderly. Clinical nutrition (Edinburgh, Scotland). vol 29. issue 1. 2010-05-12. PMID:19573960. |
the aim of this study was to determine the effect of feeding elderly patients exclusively with an n-3 polyunsaturated fatty acid-enriched diet specifically designed for enteral nutrition for 6 months, evaluating modifications in plasma fatty acid profile and some biomarkers of insulin resistance (ir). |
2010-05-12 |
2023-08-12 |
Not clear |
| Joshua Schafer, Dallas J Legare, W Wayne Laut. Acetylcholinesterase antagonist potentiated insulin action in fed but not fasted state. The Journal of pharmacology and experimental therapeutics. vol 333. issue 2. 2010-05-10. PMID:20133391. |
this meal-induced insulin sensitization results from insulin acting on the liver, in the presence of a permissive hepatic parasympathetic feeding signal and elevated hepatic glutathione (gsh), to release hepatic insulin-sensitizing substance (hiss), a hormone that acts selectively on skeletal muscle to stimulate insulin-mediated glucose uptake. |
2010-05-10 |
2023-08-12 |
rat |
| Joshua Schafer, Dallas J Legare, W Wayne Laut. Acetylcholinesterase antagonist potentiated insulin action in fed but not fasted state. The Journal of pharmacology and experimental therapeutics. vol 333. issue 2. 2010-05-10. PMID:20133391. |
blockade of the parasympathetic feeding signal to the liver, either through surgical denervation or atropine-mediated antagonism of hepatic muscarinic receptors, eliminates the hiss response, resulting in hiss-dependent insulin resistance (hdir) and decreasing the response to insulin by approximately 55% in the fed state. |
2010-05-10 |
2023-08-12 |
rat |
| Cristina Lăcătuşu, B Mihai, Cristina Cijevschi-Prelipcean, Cătălina Mihai, Mariana Grau. [Adipocitokines and nonalcoholic steatohepatitis]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. vol 112. issue 4. 2010-05-10. PMID:20209757. |
the most substantial information collected until now concerns the tumor necrosis factor alpha (a proinflammatory cytokine that induces insulin resistance, fat accumulation in the liver and even fibrosis and necrosis), adiponectin (an anti-inflammatory adipokine that acts as an insulin sensitizer and a hepatic protector) and leptin (a signal of the adipose tissue mass with effects on the appetite and food intake, but also acting upon insulin secretion and action and perhaps upon the liver fat accumulation). |
2010-05-10 |
2023-08-12 |
Not clear |
| Emilie Stolarczyk, Christophe Guissard, Aurélien Michau, Patrick C Even, Alexandra Grosfeld, Patricia Serradas, Anne Lorsignol, Luc Pénicaud, Edith Brot-Laroche, Armelle Leturque, Maude Le Gal. Detection of extracellular glucose by GLUT2 contributes to hypothalamic control of food intake. American journal of physiology. Endocrinology and metabolism. vol 298. issue 5. 2010-05-03. PMID:20179244. |
peripheral hormones (ghrelin, insulin, leptin) were unaffected, leading to a focus on central aspects of feeding behavior. |
2010-05-03 |
2023-08-12 |
mouse |
| Henriette Kirchner, Jenny Tong, Matthias H Tschöp, Paul T Pfluge. Ghrelin and PYY in the regulation of energy balance and metabolism: lessons from mouse mutants. American journal of physiology. Endocrinology and metabolism. vol 298. issue 5. 2010-05-03. PMID:20179246. |
it is acylated with a medium-chain fatty acid by the enzyme ghrelin o-acetyltransferase (goat) and displays a broad range of activity, from central control of food intake to peripheral functions such as gastric emptying and insulin secretion. |
2010-05-03 |
2023-08-12 |
mouse |
| C O Lemley, T A Wilmoth, L R Tager, K M Krause, M E Wilso. Effect of a high cornstarch diet on hepatic cytochrome P450 2C and 3A activity and progesterone half-life in dairy cows. Journal of dairy science. vol 93. issue 3. 2010-04-29. PMID:20172221. |
the objectives of the current experiment were to determine the effect of feeding 2 isoenergetic and isonitrogenous diets, formulated to cause divergent insulin secretion, on hepatic cytochrome p450 2c (cyp2c) and 3a (cyp3a) activity as well as the resulting biological half-life of progesterone. |
2010-04-29 |
2023-08-12 |
Not clear |
| C O Lemley, T A Wilmoth, L R Tager, K M Krause, M E Wilso. Effect of a high cornstarch diet on hepatic cytochrome P450 2C and 3A activity and progesterone half-life in dairy cows. Journal of dairy science. vol 93. issue 3. 2010-04-29. PMID:20172221. |
feeding diets that stimulate insulin secretion could alter progesterone clearance during lactation, when dairy cows have increased rates of progesterone inactivation because of high energy demands and increased dmi. |
2010-04-29 |
2023-08-12 |
Not clear |
| Bengt F Belgardt, Jan Mauer, F Thomas Wunderlich, Marianne B Ernst, Martin Pal, Gabriele Spohn, Hella S Brönneke, Susanne Brodesser, Brigitte Hampel, Astrid C Schauss, Jens C Brünin. Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 13. 2010-04-28. PMID:20231445. |
jnk1(deltanes) mice exhibit improved insulin sensitivity both in the cns and in peripheral tissues, improved glucose metabolism, as well as protection from hepatic steatosis and adipose tissue dysfunction upon high-fat feeding. |
2010-04-28 |
2023-08-12 |
mouse |
| Jon F Davis, Derrick L Choi, Stephen C Benoi. Insulin, leptin and reward. Trends in endocrinology and metabolism: TEM. vol 21. issue 2. 2010-04-27. PMID:19818643. |
the adiposity hormones insulin and leptin are two such signals elevated in obesity with the capacity to dampen feeding behavior through their action on hypothalamic circuits which regulate appetite and metabolism. |
2010-04-27 |
2023-08-12 |
Not clear |
| S Beck Jørgensen, H M O'Neill, K Hewitt, B E Kemp, G R Steinber. Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity. Diabetologia. vol 52. issue 11. 2010-04-26. PMID:19688337. |
we investigated whether reduced levels of muscle ampk promote lipid accumulation and insulin resistance during high-fat feeding. |
2010-04-26 |
2023-08-12 |
mouse |
| Manfred Hallschmid, Kamila Jauch-Chara, Oliver Korn, Matthias Mölle, Björn Rasch, Jan Born, Bernd Schultes, Werner Ker. Euglycemic infusion of insulin detemir compared with human insulin appears to increase direct current brain potential response and reduces food intake while inducing similar systemic effects. Diabetes. vol 59. issue 4. 2010-04-23. PMID:20068139. |
euglycemic infusion of insulin detemir compared with human insulin appears to increase direct current brain potential response and reduces food intake while inducing similar systemic effects. |
2010-04-23 |
2023-08-12 |
human |
| Manfred Hallschmid, Kamila Jauch-Chara, Oliver Korn, Matthias Mölle, Björn Rasch, Jan Born, Bernd Schultes, Werner Ker. Euglycemic infusion of insulin detemir compared with human insulin appears to increase direct current brain potential response and reduces food intake while inducing similar systemic effects. Diabetes. vol 59. issue 4. 2010-04-23. PMID:20068139. |
assuming that because of its pharmacologic properties, detemir displays stronger central nervous anorexigenic efficacy than human insulin, we compared acute effects of human insulin and detemir on electroencephalography (eeg) measures and food intake. |
2010-04-23 |
2023-08-12 |
human |
| Min Li, Jian-Hua Piao, Yuan Tian, Wei-Dong Li, Ke-Ji Li, Xiao-Guang Yan. Postprandial glycaemic and insulinaemic responses to GM-resistant starch-enriched rice and the production of fermentation-related H2 in healthy Chinese adults. The British journal of nutrition. vol 103. issue 7. 2010-04-20. PMID:19930763. |
their postprandial glycaemic and insulinaemic responses to 40 g glucose, carbohydrates of rs or wild-type (wt) rice were tested by a crossover model with a washout period of 7 d. the concentrations of blood glucose and insulin as well as breath h2 were measured before and after food intake. |
2010-04-20 |
2023-08-12 |
Not clear |
| Norma O Rizzo, Ezekiel Maloney, Matilda Pham, Ian Luttrell, Hunter Wessells, Sanshiro Tateya, Guenter Daum, Priya Handa, Michael W Schwartz, Francis Ki. Reduced NO-cGMP signaling contributes to vascular inflammation and insulin resistance induced by high-fat feeding. Arteriosclerosis, thrombosis, and vascular biology. vol 30. issue 4. 2010-04-16. PMID:20093624. |
reduced no-cgmp signaling contributes to vascular inflammation and insulin resistance induced by high-fat feeding. |
2010-04-16 |
2023-08-12 |
mouse |