| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kansuke Fujiwara, Koro Gotoh, Seiichi Chiba, Takayuki Masaki, Isao Katsuragi, Tetsuya Kakuma, Hironobu Yoshimats. Intraportal administration of DPP-IV inhibitor regulates insulin secretion and food intake mediated by the hepatic vagal afferent nerve in rats. Journal of neurochemistry. vol 121. issue 1. 2012-05-03. PMID:22035323. |
the effect of dpp-iv inhibitor infusion into the portal vein or peritoneum on portal and peripheral glp-1 levels, food intake, and plasma insulin and glucose was examined in sham-operated and vagotomized male sprague-dawley rats. |
2012-05-03 |
2023-08-12 |
rat |
| Kansuke Fujiwara, Koro Gotoh, Seiichi Chiba, Takayuki Masaki, Isao Katsuragi, Tetsuya Kakuma, Hironobu Yoshimats. Intraportal administration of DPP-IV inhibitor regulates insulin secretion and food intake mediated by the hepatic vagal afferent nerve in rats. Journal of neurochemistry. vol 121. issue 1. 2012-05-03. PMID:22035323. |
our results indicate that dpp-iv inhibitor-induced changes in portal but not systemic glp-1 levels affect insulin secretion and food intake. |
2012-05-03 |
2023-08-12 |
rat |
| E N Ponnampalam, R D Warner, F R Dunshe. Basal and hormone-stimulated metabolism in lambs varies with breed and diet quality. Domestic animal endocrinology. vol 42. issue 2. 2012-05-03. PMID:22119112. |
after 3 wk of feeding, lambs were injected intravenously with insulin (10 μg/kg body weight [bw]) and epinephrine (0.8 μg/kg bw) on consecutive days and blood samples were collected at -30, -15, -1, 3, 6, 10, 15, 20, 30, 45, 60, 90, and 120 min relative to time of injection. |
2012-05-03 |
2023-08-12 |
Not clear |
| Denovan P Begg, Stephen C Wood. The central insulin system and energy balance. Handbook of experimental pharmacology. issue 209. 2012-04-25. PMID:22249812. |
within the brain, insulin produces a net catabolic effect by reducing food intake and increasing energy expenditure; this is evidenced by the hypophagia and increased brown adipose tissue sympathetic nerve activity induced by central insulin infusion. |
2012-04-25 |
2023-08-12 |
Not clear |
| Denovan P Begg, Stephen C Wood. The central insulin system and energy balance. Handbook of experimental pharmacology. issue 209. 2012-04-25. PMID:22249812. |
however, despite decades of research into the role of central insulin in food intake, many questions remain to be answered, including the underlying mechanism of action. |
2012-04-25 |
2023-08-12 |
Not clear |
| S R Veena, G V Krishnaveni, A K Wills, J C Hill, S C Karat, C H D Fal. Glucose tolerance and insulin resistance in Indian children: relationship to infant feeding pattern. Diabetologia. vol 54. issue 10. 2012-04-24. PMID:21773682. |
glucose tolerance and insulin resistance in indian children: relationship to infant feeding pattern. |
2012-04-24 |
2023-08-12 |
Not clear |
| Yingmei Zhang, Ming Yuan, Katherine M Bradley, Feng Dong, Piero Anversa, Jun Re. Insulin-like growth factor 1 alleviates high-fat diet-induced myocardial contractile dysfunction: role of insulin signaling and mitochondrial function. Hypertension (Dallas, Tex. : 1979). vol 59. issue 3. 2012-04-17. PMID:22275536. |
high-fat diet feeding led to glucose intolerance, elevated plasma levels of leptin, interleukin 6, insulin, and triglyceride, as well as reduced circulating igf-1 levels. |
2012-04-17 |
2023-08-12 |
mouse |
| Roberta Barone Lumaga, Danilo Azzali, Vincenzo Fogliano, Luca Scalfi, Paola Vitaglion. Sugar and dietary fibre composition influence, by different hormonal response, the satiating capacity of a fruit-based and a β-glucan-enriched beverage. Food & function. vol 3. issue 1. 2012-04-16. PMID:22057424. |
appetite ratings over 3 h post-breakfast and energy intakes at ad libitum lunch, blood glucose, insulin, ghrelin, pyy, glp-1, gip, and pp concentrations, and 24 h food intake, were assessed. |
2012-04-16 |
2023-08-12 |
human |
| Emma Burgos-Ramos, Agueda González-Rodríguez, Sandra Canelles, Eva Baquedano, Laura M Frago, Jesús Revuelta-Cervantes, Javier Gómez-Ambrosi, Gema Frühbeck, Julie A Chowen, Jesús Argente, Angela M Valverde, Vicente Barrio. Differential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide Y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/- mice. Endocrinology. vol 153. issue 3. 2012-04-16. PMID:22210743. |
our aim was to analyze how leptin and insulin signaling may differentially affect the expression of hypothalamic neuropeptides regulating food intake and hypothalamic inflammation in diabetic (d) and nondiabetic (nd) irs2(-/-) mice. |
2012-04-16 |
2023-08-12 |
mouse |
| Nicole Speed, Christine Saunders, Adeola R Davis, W Anthony Owens, Heinrich J G Matthies, Sanaz Saadat, Jack P Kennedy, Roxanne A Vaughan, Rachael L Neve, Craig W Lindsley, Scott J Russo, Lynette C Daws, Kevin D Niswender, Aurelio Gall. Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding. PloS one. vol 6. issue 9. 2012-04-13. PMID:21969871. |
we demonstrate a molecular link between impairment of a central kinase (akt) involved in insulin signaling induced by exposure to a high-fat (hf) diet and dysregulation of higher order circuitry involved in feeding. |
2012-04-13 |
2023-08-12 |
Not clear |
| Nicole Speed, Christine Saunders, Adeola R Davis, W Anthony Owens, Heinrich J G Matthies, Sanaz Saadat, Jack P Kennedy, Roxanne A Vaughan, Rachael L Neve, Craig W Lindsley, Scott J Russo, Lynette C Daws, Kevin D Niswender, Aurelio Gall. Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding. PloS one. vol 6. issue 9. 2012-04-13. PMID:21969871. |
insulin, a hormone in the periphery, also acts centrally to regulate both homeostatic and reward-based hf feeding. |
2012-04-13 |
2023-08-12 |
Not clear |
| Nicole Speed, Christine Saunders, Adeola R Davis, W Anthony Owens, Heinrich J G Matthies, Sanaz Saadat, Jack P Kennedy, Roxanne A Vaughan, Rachael L Neve, Craig W Lindsley, Scott J Russo, Lynette C Daws, Kevin D Niswender, Aurelio Gall. Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding. PloS one. vol 6. issue 9. 2012-04-13. PMID:21969871. |
upon hf feeding, nigro-striatal neurons rapidly develop insulin signaling deficiencies, causing increased hf calorie intake. |
2012-04-13 |
2023-08-12 |
Not clear |
| Maricela Rodríguez-Cruz, Raúl Sánchez González, Apolos M Sánchez García, Mardia Lòpez-Alarcò. Coexisting role of fasting or feeding and dietary lipids in the control of gene expression of enzymes involved in the synthesis of saturated, monounsaturated and polyunsaturated fatty acids. Gene. vol 496. issue 1. 2012-04-13. PMID:22248624. |
the aim of this study was to evaluate the coexisting role of physiological (insulin, fasting and feeding) and exogenous (dietary lipids) factors in the control of gene expression of fasn, elongases and desaturases via srebf-1c in liver from rats. |
2012-04-13 |
2023-08-12 |
rat |
| Maricela Rodríguez-Cruz, Raúl Sánchez González, Apolos M Sánchez García, Mardia Lòpez-Alarcò. Coexisting role of fasting or feeding and dietary lipids in the control of gene expression of enzymes involved in the synthesis of saturated, monounsaturated and polyunsaturated fatty acids. Gene. vol 496. issue 1. 2012-04-13. PMID:22248624. |
finally, upregulation by feeding (insulin) of fasn, scd, fads2 and srebf-1c is insufficient to compensate for the inhibitory effect of dietary lipids. |
2012-04-13 |
2023-08-12 |
rat |
| Christopher G Owen, Peter H Whincup, Derek G Coo. Breast-feeding and cardiovascular risk factors and outcomes in later life: evidence from epidemiological studies. The Proceedings of the Nutrition Society. vol 70. issue 4. 2012-04-04. PMID:21801475. |
there is no strong evidence to suggest effects of early feeding on adult levels of blood glucose, blood insulin and chd outcomes, although further data are needed. |
2012-04-04 |
2023-08-12 |
Not clear |
| Dario A Gutierrez, Alyssa H Hast. Haematopoietic leptin receptor deficiency does not affect macrophage accumulation in adipose tissue or systemic insulin sensitivity. The Journal of endocrinology. vol 212. issue 3. 2012-04-04. PMID:22194312. |
in addition, no changes in glucose or insulin tolerance were observed between groups after either period of hfd feeding. |
2012-04-04 |
2023-08-12 |
mouse |
| Yuko Maejima, Daisuke Kohno, Yusaku Iwasaki, Toshihiko Yad. Insulin suppresses ghrelin-induced calcium signaling in neuropeptide Y neurons of the hypothalamic arcuate nucleus. Aging. vol 3. issue 11. 2012-04-02. PMID:22081645. |
our results suggest that postprandial increase in plasma insulin/ghrelin ratio and insulin inhibition of ghrelin action on arc npy neurons cooperate to effectively inhibit the neuron activity and terminate feeding. |
2012-04-02 |
2023-08-12 |
rat |
| Zhen Pang, Nancy N Wu, Weiguang Zhao, David C Chain, Erica Schaffer, Xin Zhang, Preeti Yamdagni, Vaseem A Palejwala, Chunpeng Fan, Sarah G Favara, Holly M Dressler, Kyriakos D Economides, Daniel Weinstock, Jean S Cavallo, Souad Naimi, Anne-Marie Galzin, Etienne Guillot, Marie-Pierre Pruniaux, Michael J Tocci, H Greg Polite. The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice. Obesity (Silver Spring, Md.). vol 19. issue 10. 2012-03-27. PMID:21799481. |
compared to wild-type (wt) littermates, the mutant mice displayed reduced body weight (bw), adiposity, and feeding efficiency, and when fed a high-fat diet (hfd), showed decreased plasma insulin, leptin, cholesterol, and triglyceride levels, and elevated adiponectin levels. |
2012-03-27 |
2023-08-12 |
mouse |
| Hye-Jin Kim, Masaki Kobayashi, Tsutomu Sasaki, Osamu Kikuchi, Kosuke Amano, Tomoya Kitazumi, Yong-Soo Lee, Hiromi Yokota-Hashimoto, Vina Yanti Susanti, Yukari Ido Kitamura, Jun Nakae, Tadahiro Kitamur. Overexpression of FoxO1 in the hypothalamus and pancreas causes obesity and glucose intolerance. Endocrinology. vol 153. issue 2. 2012-03-27. PMID:22186407. |
the ki mice developed obesity, insulin resistance, glucose intolerance, and hypertriglyceridemia due to increased food intake, decreased energy expenditure, and impaired insulin secretion, which characterize metabolic syndrome. |
2012-03-27 |
2023-08-12 |
mouse |
| Deon B Williams, Zhongxiao Wan, Bruce C Frier, Rhonda C Bell, Catherine J Field, David C Wrigh. Dietary supplementation with vitamin E and C attenuates dexamethasone-induced glucose intolerance in rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 302. issue 1. 2012-03-26. PMID:22031784. |
we hypothesized that feeding rats a diet supplemented with vit e/c would improve glucose tolerance and restore insulin signaling in skeletal muscle, adipose, and liver and prevent alterations in ampk signaling in these tissues. |
2012-03-26 |
2023-08-12 |
rat |