| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhuo Fu, Elizabeth R Gilbert, Liliane Pfeiffer, Yanling Zhang, Yu Fu, Dongmin Li. Genistein ameliorates hyperglycemia in a mouse model of nongenetic type 2 diabetes. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 37. issue 3. 2012-07-26. PMID:22509809. |
dietary intake of genistein (250 mg·kg(-1) diet) improved hyperglycemia, glucose tolerance, and blood insulin level in obese diabetic mice, whereas it did not affect body weight gain, food intake, fat deposit, plasma lipid profile, and peripheral insulin sensitivity. |
2012-07-26 |
2023-08-12 |
mouse |
| Yeon Ja Choi, Dae Hyun Kim, Eun Kyeong Lee, Ji Min Kim, Young Mi Ha, Nam Deuk Kim, Jee H Jung, Jae Sue Choi, Byung Pal Yu, Hae Young Chun. Attenuation of age-related changes in FOXO3a activity and the PI3K/Akt pathway by short-term feeding of ferulate. Age (Dordrecht, Netherlands). vol 34. issue 2. 2012-07-24. PMID:21468671. |
the present study investigated the efficacy of short-term ferulate feeding on age-related changes in pi3k/akt/foxo3a and upstream insulin signaling pathways in aged rats. |
2012-07-24 |
2023-08-12 |
rat |
| Yeon Ja Choi, Dae Hyun Kim, Eun Kyeong Lee, Ji Min Kim, Young Mi Ha, Nam Deuk Kim, Jee H Jung, Jae Sue Choi, Byung Pal Yu, Hae Young Chun. Attenuation of age-related changes in FOXO3a activity and the PI3K/Akt pathway by short-term feeding of ferulate. Age (Dordrecht, Netherlands). vol 34. issue 2. 2012-07-24. PMID:21468671. |
the significance of the present study is the finding that short-term feeding of ferulate effectively modulates age-related renal foxo3a, pi3k/akt and insulin signaling pathways, and mnsod and catalase expression, all of which may be beneficial for attenuating the aging process. |
2012-07-24 |
2023-08-12 |
rat |
| Ewan C McNay, Andrew K Recknage. Reprint of: 'Brain insulin signaling: A key component of cognitive processes and a potential basis for cognitive impairment in type 2 diabetes'. Neurobiology of learning and memory. vol 96. issue 4. 2012-07-19. PMID:22085799. |
understanding of the role of insulin in the brain has gradually expanded, from initial conceptions of the brain as insulin-insensitive through identification of a role in regulation of feeding, to recent demonstration of insulin as a key component of hippocampal memory processes. |
2012-07-19 |
2023-08-12 |
Not clear |
| Matthias Blühe. Vaspin in obesity and diabetes: pathophysiological and clinical significance. Endocrine. vol 41. issue 2. 2012-07-19. PMID:22139797. |
administration of vaspin to obese mice improves glucose tolerance, insulin sensitivity, and reduces food intake. |
2012-07-19 |
2023-08-12 |
mouse |
| R Barazzoni, M Zanetti, G Gortan Cappellari, A Semolic, M Boschelle, E Codarin, A Pirulli, L Cattin, G Guarnier. Fatty acids acutely enhance insulin-induced oxidative stress and cause insulin resistance by increasing mitochondrial reactive oxygen species (ROS) generation and nuclear factor-κB inhibitor (IκB)-nuclear factor-κB (NFκB) activation in rat muscle, in the absence of mitochondrial dysfunction. Diabetologia. vol 55. issue 3. 2012-07-19. PMID:22159911. |
insulin effects reportedly involve reactive oxygen species (ros) and oxidative stress in vitro, but skeletal muscle oxidative stress is an emerging negative regulator of insulin action following high-fat feeding. |
2012-07-19 |
2023-08-12 |
rat |
| Steven G Chrysant, George S Chrysan. Clinical implications of cardiovascular preventing pleiotropic effects of dipeptidyl peptidase-4 inhibitors. The American journal of cardiology. vol 109. issue 11. 2012-07-19. PMID:22425330. |
these 2 incretins lower blood glucose levels and postprandial hyperglycemia by stimulating insulin release from b cells of the pancreas, thus increasing insulin sensitivity, delaying gastrointestinal emptying, decreasing food intake through early satiety, and causing weight loss in the long term. |
2012-07-19 |
2023-08-12 |
Not clear |
| K Sato, T Takahashi, Y Kobayashi, A Hagino, S G Roh, K Kato. Apelin is involved in postprandial responses and stimulates secretion of arginine-vasopressin, adrenocorticotropic hormone, and growth hormone in the ruminant. Domestic animal endocrinology. vol 42. issue 3. 2012-07-17. PMID:22177697. |
therefore, the aims of this study were to investigate the following: (1) changes in plasma apelin concentrations in response to food intake under conditions of hydration (free access to water) or dehydration (water restriction), and (2) the effects of intravenous administration of apelin on plasma concentrations of arginine-vasopressin (avp), acth, gh, and insulin. |
2012-07-17 |
2023-08-12 |
Not clear |
| C Vaquerizo Alonso, T Grau Carmona, M Juan Día. Guidelines for specialized nutritional and metabolic support in the critically-ill patient: update. Consensus SEMICYUC-SENPE: hyperglycemia and diabetes mellitus. Nutricion hospitalaria. vol 26 Suppl 2. 2012-07-11. PMID:22411519. |
whenever patients require artificial feeding, the enteral route, if not contraindicated, should be used since parenteral nutrition is associated with a higher frequency of hyperglycemia and greater insulin requirements. |
2012-07-11 |
2023-08-12 |
Not clear |
| Jiang Wei Wu, Shu Pei Wang, Stéphanie Casavant, Alain Moreau, Gong She Yang, Grant A Mitchel. Fasting energy homeostasis in mice with adipose deficiency of desnutrin/adipose triglyceride lipase. Endocrinology. vol 153. issue 5. 2012-06-29. PMID:22374972. |
under fed conditions, atglako mice had normal viability, mild obesity, low plasma nonesterified fatty acid levels, increased insulin sensitivity, and increased daytime food intake. |
2012-06-29 |
2023-08-12 |
mouse |
| Dumitru Constantin-Teodosiu, Despina Constantin, Francis Stephens, David Laithwaite, Paul L Greenhaf. The role of FOXO and PPAR transcription factors in diet-mediated inhibition of PDC activation and carbohydrate oxidation during exercise in humans and the role of pharmacological activation of PDC in overriding these changes. Diabetes. vol 61. issue 5. 2012-06-28. PMID:22315317. |
high-fat feeding inhibits pyruvate dehydrogenase complex (pdc)-controlled carbohydrate (cho) oxidation, which contributes to muscle insulin resistance. |
2012-06-28 |
2023-08-12 |
human |
| Hagai Ligumsky, Ido Wolf, Shira Israeli, Michal Haimsohn, Sarah Ferber, Avraham Karasik, Bella Kaufman, Tami Rubine. The peptide-hormone glucagon-like peptide-1 activates cAMP and inhibits growth of breast cancer cells. Breast cancer research and treatment. vol 132. issue 2. 2012-06-22. PMID:21638053. |
the incretin hormone glucagon-like peptide (glp)-1 is secreted from intestinal l cells in response to food intake, and promotes insulin secretion and pancreatic β-cell proliferation. |
2012-06-22 |
2023-08-12 |
mouse |
| Yiguo Wang, Gang Li, Jason Goode, Jose C Paz, Kunfu Ouyang, Robert Screaton, Wolfgang H Fischer, Ju Chen, Ira Tabas, Marc Montmin. Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature. vol 485. issue 7396. 2012-06-19. PMID:22495310. |
during feeding, increases in insulin signalling reduced crtc2 activity via the akt-mediated inactivation of insp(3)rs. |
2012-06-19 |
2023-08-12 |
mouse |
| Delphine Verrier, Shannon Atkinson, Christophe Guinet, René Groscolas, John P Y Arnoul. Hormonal responses to extreme fasting in subantarctic fur seal (Arctocephalus tropicalis) pups. American journal of physiology. Regulatory, integrative and comparative physiology. vol 302. issue 8. 2012-06-18. PMID:22319050. |
the early fall in insulin and leptin may mediate the shift to the strategy of energy conservation, protein sparing, and primary reliance on body lipids observed in response to the cessation of feeding. |
2012-06-18 |
2023-08-12 |
Not clear |
| Mingjian Lu, Min Wan, Karla F Leavens, Qingwei Chu, Bobby R Monks, Sully Fernandez, Rexford S Ahima, Kohjiro Ueki, C Ronald Kahn, Morris J Birnbau. Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1. Nature medicine. vol 18. issue 3. 2012-06-18. PMID:22344295. |
here we show that mice with hepatic deletion of akt1 and akt2 were glucose intolerant, insulin resistant and defective in their transcriptional response to feeding in the liver. |
2012-06-18 |
2023-08-12 |
mouse |
| Lu-Ping Ren, Stanley M H Chan, Xiao-Yi Zeng, D Ross Laybutt, Tristan J Iseli, Ruo-Qiong Sun, Edward W Kraegen, Gregory J Cooney, Nigel Turner, Ji-Ming Y. Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance. PloS one. vol 7. issue 2. 2012-06-18. PMID:22355328. |
the fact that er stress is apparent only with hfru feeding suggests that er stress is involved in dnl per se rather than resulting from hepatic steatosis or insulin resistance. |
2012-06-18 |
2023-08-12 |
mouse |
| Harish Vasudevan, Violet G Yuen, John H McNeil. Testosterone-dependent increase in blood pressure is mediated by elevated Cyp4A expression in fructose-fed rats. Molecular and cellular biochemistry. vol 359. issue 1-2. 2012-06-15. PMID:21894443. |
in the first study, intact and castrated male rats were made insulin resistant by feeding fructose for 9 weeks following which their superior mesenteric arteries (sma) were isolated and examined for changes in endothelium-dependent relaxation in the presence and absence of 1-aminobenzotriazole (abt) and n-methylsulfonyl-12,12-dibromododec-11-enamide (ddms), which are inhibitors of 20-hete synthesis. |
2012-06-15 |
2023-08-12 |
rat |
| C Vaquerizo Alonso, T Grau Carmona, M Juan Día. [Guidelines for specialized nutritional and metabolic support in the critically-ill patient. Update. Consensus of the Spanish Society of Intensive Care Medicine and Coronary Units-Spanish Society of Parenteral and Enteral Nutrition (SEMICYUC-SENPE): hyperglycemia and diabetes mellitus]. Medicina intensiva. vol 35 Suppl 1. 2012-06-14. PMID:22309753. |
whenever patients require artificial feeding, the enteral route, if not contraindicated, should be used since parenteral nutrition is associated with a higher frequency of hyperglycemia and greater insulin requirements. |
2012-06-14 |
2023-08-12 |
Not clear |
| D T Yates, C A Löest, T T Ross, D M Hallford, B H Carter, S W Limesan. Effects of bacterial lipopolysaccharide injection on white blood cell counts, hematological variables, and serum glucose, insulin, and cortisol concentrations in ewes fed low- or high-protein diets. Journal of animal science. vol 89. issue 12. 2012-06-12. PMID:21788428. |
feeding high-cp diets for 10 d did not reduce inflammation in ewes during the first 24 h after lps exposure but may benefit livestock by preventing acute insulin resistance when endotoxin exposure is mild. |
2012-06-12 |
2023-08-12 |
Not clear |
| P Moriel, V Nayigihugu, B I Cappellozza, E P Gonçalves, J M Krall, T Foulke, K M Cammack, B W Hes. Camelina meal and crude glycerin as feed supplements for developing replacement beef heifers. Journal of animal science. vol 89. issue 12. 2012-06-12. PMID:21821818. |
angus × gelbvieh rotationally crossbred yearling heifers (n = 99, yr 1; n = 105, yr 2) were used in a 2-yr randomized complete block design experiment with repeated measures to determine the effect of feeding camelina biodiesel coproducts (meal and crude glycerin) on serum concentrations of triiodothyronine, thyroxine, insulin, β-hydroxybutyrate, and glucose, as well as on growth and reproductive performance. |
2012-06-12 |
2023-08-12 |
Not clear |