| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I S McGregor, J A Menéndez, D M Atren. Metabolic effects of neuropeptide Y injected into the sulcal prefrontal cortex. Brain research bulletin. vol 24. issue 3. 1990-06-20. PMID:2337816. |
this combination of effects, namely increased carbohydrate utilization, fat synthesis and food intake with reduced energy expenditure, shows npy to be a potent anabolic force. |
1990-06-20 |
2023-08-11 |
Not clear |
| W T Chance, S Sheriff, T Foley-Nelson, J E Fischer, A Balasubramania. Pertussis toxin inhibits neuropeptide Y-induced feeding in rats. Peptides. vol 10. issue 6. 1990-03-19. PMID:2560178. |
neuropeptide y (npy) is the most powerful peptide drug stimulating feeding in rats. |
1990-03-19 |
2023-08-11 |
rat |
| W T Chance, S Sheriff, T Foley-Nelson, J E Fischer, A Balasubramania. Pertussis toxin inhibits neuropeptide Y-induced feeding in rats. Peptides. vol 10. issue 6. 1990-03-19. PMID:2560178. |
consistent with previous reports, injection of 2 micrograms of npy into the pvh significantly increased the cumulative food intake over 1-, 2- and 4-hr periods. |
1990-03-19 |
2023-08-11 |
rat |
| W T Chance, S Sheriff, T Foley-Nelson, J E Fischer, A Balasubramania. Pertussis toxin inhibits neuropeptide Y-induced feeding in rats. Peptides. vol 10. issue 6. 1990-03-19. PMID:2560178. |
pt had no immediate effect on npy-induced feeding; however, four days after pt was injected npy (2 micrograms) did not increase the food intake compared to control. |
1990-03-19 |
2023-08-11 |
rat |
| J D White, D Olchovsky, M Kershaw, M Berelowit. Increased hypothalamic content of preproneuropeptide-Y messenger ribonucleic acid in streptozotocin-diabetic rats. Endocrinology. vol 126. issue 2. 1990-03-05. PMID:2404748. |
neuropeptide-y (npy) is a 36-amino acid c-terminally amidated peptide found within the hypothalamus that can potently stimulate carbohydrate feeding. |
1990-03-05 |
2023-08-11 |
rat |
| J F Flood, J E Morle. Dissociation of the effects of neuropeptide Y on feeding and memory: evidence for pre- and postsynaptic mediation. Peptides. vol 10. issue 5. 1990-02-16. PMID:2558366. |
npy elicited a 544% increase in feeding compared to the saline control. |
1990-02-16 |
2023-08-11 |
mouse |
| J F Flood, J E Morle. Dissociation of the effects of neuropeptide Y on feeding and memory: evidence for pre- and postsynaptic mediation. Peptides. vol 10. issue 5. 1990-02-16. PMID:2558366. |
neither npy fragment significantly increased feeding. |
1990-02-16 |
2023-08-11 |
mouse |
| J F Flood, J E Morle. Dissociation of the effects of neuropeptide Y on feeding and memory: evidence for pre- and postsynaptic mediation. Peptides. vol 10. issue 5. 1990-02-16. PMID:2558366. |
both npy and npy(20-36) resulted in amnesia, but only npy stimulated feeding. |
1990-02-16 |
2023-08-11 |
mouse |
| J F Flood, J E Morle. Dissociation of the effects of neuropeptide Y on feeding and memory: evidence for pre- and postsynaptic mediation. Peptides. vol 10. issue 5. 1990-02-16. PMID:2558366. |
these results are compatible with npy effects on feeding being mediated through postsynaptic (y1)npy receptors and effects on memory retention being mediated through presynaptic (y2)npy receptors. |
1990-02-16 |
2023-08-11 |
mouse |
| A Sahu, C A Sninsky, P S Kalra, S P Kalr. Neuropeptide-Y concentration in microdissected hypothalamic regions and in vitro release from the medial basal hypothalamus-preoptic area of streptozotocin-diabetic rats with and without insulin substitution therapy. Endocrinology. vol 126. issue 1. 1990-02-07. PMID:2136723. |
neuropeptide-y (npy) stimulates pituitary gonadotropin release, inhibits sexual behavior, and stimulates robust feeding in rats by acting at different sites in the hypothalamus. |
1990-02-07 |
2023-08-11 |
rat |
| A Sahu, C A Sninsky, P S Kalra, S P Kalr. Neuropeptide-Y concentration in microdissected hypothalamic regions and in vitro release from the medial basal hypothalamus-preoptic area of streptozotocin-diabetic rats with and without insulin substitution therapy. Endocrinology. vol 126. issue 1. 1990-02-07. PMID:2136723. |
in the stz-d rats, npy concentrations in six of the seven microdissected nuclei, including those mediating control of pituitary gonadotropin, sexual, and feeding behaviors, were increased compared to control values. |
1990-02-07 |
2023-08-11 |
rat |
| B G Stanley, K C Anderson, M H Grayson, S F Leibowit. Repeated hypothalamic stimulation with neuropeptide Y increases daily carbohydrate and fat intake and body weight gain in female rats. Physiology & behavior. vol 46. issue 2. 1990-01-30. PMID:2602454. |
relative to vehicle or preinjection rates of body weight gain (approximately 1.5 g/day), npy dramatically enhanced weight gain to a rate of 9.3 g/day and more than doubled total daily food intake. |
1990-01-30 |
2023-08-11 |
rat |
| L Calzá, L Giardino, N Battistini, M Zanni, S Galetti, F Protopapa, A Velard. Increase of neuropeptide Y-like immunoreactivity in the paraventricular nucleus of fasting rats. Neuroscience letters. vol 104. issue 1-2. 1989-12-20. PMID:2682395. |
this result suggests a physiological role of npy in the food intake regulation at the pvh level. |
1989-12-20 |
2023-08-11 |
rat |
| B G Stanley, D Lanthier, A S Chin, S F Leibowit. Suppression of neuropeptide Y-elicited eating by adrenalectomy or hypophysectomy: reversal with corticosterone. Brain research. vol 501. issue 1. 1989-12-20. PMID:2804697. |
in unoperated or sham groups, npy elicited 5.7-8.8 g of food intake in 1 h as compared to 0.4-1.1 g for vehicle-injected animals. |
1989-12-20 |
2023-08-11 |
rat |
| H Shimizu, G A Bra. Effects of neuropeptide Y on norepinephrine and serotonin metabolism in rat hypothalamus in vivo. Brain research bulletin. vol 22. issue 6. 1989-11-08. PMID:2477116. |
npy is known to stimulate food intake when injected into either area. |
1989-11-08 |
2023-08-11 |
rat |
| H Shimizu, G A Bra. Effects of neuropeptide Y on norepinephrine and serotonin metabolism in rat hypothalamus in vivo. Brain research bulletin. vol 22. issue 6. 1989-11-08. PMID:2477116. |
the present data are consistent with the concept that a reduction in concentration of serotonin is involved in the regulation of food intake following injection of npy. |
1989-11-08 |
2023-08-11 |
rat |
| J E Morley, J F Floo. The effect of neuropeptide Y on drinking in mice. Brain research. vol 494. issue 1. 1989-10-06. PMID:2765911. |
in these studies we demonstrated that, in contrast, in mice npy inhibits drinking induced by water deprivation and that associated with food intake. |
1989-10-06 |
2023-08-11 |
mouse |
| J E Morley, J F Floo. The effect of neuropeptide Y on drinking in mice. Brain research. vol 494. issue 1. 1989-10-06. PMID:2765911. |
npy inhibited drinking and enhanced feeding in msg treated mice. |
1989-10-06 |
2023-08-11 |
mouse |
| M Y Pau, K Y Pau, H G Spie. Characterization of central actions of neuropeptide Y on food and water intake in rabbits. Physiology & behavior. vol 44. issue 6. 1989-07-12. PMID:3249755. |
unlike studies in rats, in these rabbits npy elicited a more pronounced response in drinking than in feeding. |
1989-07-12 |
2023-08-11 |
rat |
| M Y Pau, K Y Pau, H G Spie. Characterization of central actions of neuropeptide Y on food and water intake in rabbits. Physiology & behavior. vol 44. issue 6. 1989-07-12. PMID:3249755. |
the drinking response after npy administration was not a consequence of food intake because it occurred in the absence of food. |
1989-07-12 |
2023-08-11 |
rat |