Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Y Pau, K Y Pau, H G Spie. Characterization of central actions of neuropeptide Y on food and water intake in rabbits. Physiology & behavior. vol 44. issue 6. 1989-07-12. PMID:3249755. |
with ad lib feeding, the majority of enhanced food consumption was confined to the first 30-min after npy injection; however, an increased motivation to eat was retained for at least 2 hr after npy when food was withheld and then returned. |
1989-07-12 |
2023-08-11 |
rat |
A Sahu, M G Dube, S P Kalra, P S Kalr. Bilateral neural transections at the level of mesencephalon increase food intake and reduce latency to onset of feeding in response to neuropeptide Y. Peptides. vol 9. issue 6. 1989-06-20. PMID:3247249. |
administration of neuropeptide y (npy) into the iiird ventricle of the rat brain induces robust ingestive behavior with a latency to onset of feeding (lof) ranging from 12 to 20 min. |
1989-06-20 |
2023-08-11 |
rat |
A Sahu, M G Dube, S P Kalra, P S Kalr. Bilateral neural transections at the level of mesencephalon increase food intake and reduce latency to onset of feeding in response to neuropeptide Y. Peptides. vol 9. issue 6. 1989-06-20. PMID:3247249. |
since substantial amounts of npy found in hypothalamic sites that mediate the control of feeding behavior originate from the brain stem, we studied the effects of npy on lof and food intake in male and female rats after bilateral severing of brain stem npy input to the hypothalamus at the level of the mesencephalon. |
1989-06-20 |
2023-08-11 |
rat |
A Sahu, M G Dube, S P Kalra, P S Kalr. Bilateral neural transections at the level of mesencephalon increase food intake and reduce latency to onset of feeding in response to neuropeptide Y. Peptides. vol 9. issue 6. 1989-06-20. PMID:3247249. |
npy in doses of 117 pmol significantly increased food intake and decreased lof in both male and female transected rats. |
1989-06-20 |
2023-08-11 |
rat |
P J Kulkosky, G W Glazner, H D Moore, C A Low, S C Wood. Neuropeptide Y: behavioral effects in the golden hamster. Peptides. vol 9. issue 6. 1989-06-20. PMID:3247255. |
to assess npy's behavioral effects in a new world rodent that does not increase food intake after deprivation, npy was injected intracerebroventricularly (10.0-0.04 micrograms/5 microliter) in home-caged golden hamsters with ad lib access to food, water and 5% w/v ethanol solution. |
1989-06-20 |
2023-08-11 |
mouse |
P J Kulkosky, G W Glazner, H D Moore, C A Low, S C Wood. Neuropeptide Y: behavioral effects in the golden hamster. Peptides. vol 9. issue 6. 1989-06-20. PMID:3247255. |
npy promptly increased short-term food intake and observed feeding behaviors at 10.0, 3.3, 1.1, and 0.37 micrograms npy, but there was no effect on 24 hr food intake. |
1989-06-20 |
2023-08-11 |
mouse |
P J Kulkosky, G W Glazner, H D Moore, C A Low, S C Wood. Neuropeptide Y: behavioral effects in the golden hamster. Peptides. vol 9. issue 6. 1989-06-20. PMID:3247255. |
resting behaviors decreased at npy doses that increased feeding, but there were no consistent effects of npy on any other category of behavior. |
1989-06-20 |
2023-08-11 |
mouse |
P J Kulkosky, G W Glazner, H D Moore, C A Low, S C Wood. Neuropeptide Y: behavioral effects in the golden hamster. Peptides. vol 9. issue 6. 1989-06-20. PMID:3247255. |
results demonstrate that npy potently stimulates short-term food intake and decreases resting behavior in the golden hamster. |
1989-06-20 |
2023-08-11 |
mouse |
W Danho, J Triscari, G Vincent, T Nakajima, J Taylor, E T Kaise. Synthesis and biological evaluation of pNPY fragments. International journal of peptide and protein research. vol 32. issue 6. 1989-06-15. PMID:2854537. |
these fragments were assayed for npy receptor binding activity in the rat hypothalamus membrane preparation, enhancement of food intake in the rat following ivt administration and inhibition of electrically stimulated muscle contraction in the rat vas deferens. |
1989-06-15 |
2023-08-11 |
rat |
N E Rowlan. Peripheral and central satiety factors in neuropeptide Y-induced feeding in rats. Peptides. vol 9. issue 5. 1989-05-26. PMID:3244566. |
in the first study, injection of npy into the hypothalamic paraventricular nucleus (pvn) caused a robust feeding effect that was attenuated by intravenous infusions of glucose, but not fructose. |
1989-05-26 |
2023-08-11 |
human |
N E Rowlan. Peripheral and central satiety factors in neuropeptide Y-induced feeding in rats. Peptides. vol 9. issue 5. 1989-05-26. PMID:3244566. |
it is suggested that increased blood glucose has a direct central effect on npy feeding mechanisms. |
1989-05-26 |
2023-08-11 |
human |
W J Kuenzel, J McMurtr. Neuropeptide Y: brain localization and central effects on plasma insulin levels in chicks. Physiology & behavior. vol 44. issue 4-5. 1989-05-05. PMID:3070587. |
since the immunocytochemical study showed that npy was localized in brain structures known to alter food intake and the compound is a member of the pancreatic polypeptide family, a second study was designed to determine if the neuropeptide altered plasma concentrations of insulin, glucagon and glucose following intracerebroventricular administration. |
1989-05-05 |
2023-08-11 |
Not clear |
A Sahu, P S Kalra, M G Dube, S P Kalr. Neuropeptide K suppresses feeding in the rat. Regulatory peptides. vol 23. issue 2. 1989-04-11. PMID:3231743. |
however, when administered centrally prior to npy injection, npk delayed the onset of feeding response only. |
1989-04-11 |
2023-08-11 |
rat |
S P Kalra, M G Dube, P S Kalr. Continuous intraventricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats: effects of adrenalectomy and cholecystokinin. Peptides. vol 9. issue 4. 1989-04-04. PMID:3226950. |
in these studies the pattern of feeding behavior during continuous intraventricular (ivt) infusion of npy for 4 hr in the satiated female rat was monitored. |
1989-04-04 |
2023-08-11 |
rat |
S P Kalra, M G Dube, P S Kalr. Continuous intraventricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats: effects of adrenalectomy and cholecystokinin. Peptides. vol 9. issue 4. 1989-04-04. PMID:3226950. |
whereas saline infusion was ineffective, each of the three doses of npy (117, 470 or 1175 pmol/hr) increased feeding during the entire 4 hr infusion and 2 hr postinfusion period. |
1989-04-04 |
2023-08-11 |
rat |
S P Kalra, M G Dube, P S Kalr. Continuous intraventricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats: effects of adrenalectomy and cholecystokinin. Peptides. vol 9. issue 4. 1989-04-04. PMID:3226950. |
the cumulative food intake at the end of 4 hr of npy infusion was enhanced in a dose-related fashion between 0, 117 and 470 pmol/hr; at 1175 pmol/hr food intake plateaued. |
1989-04-04 |
2023-08-11 |
rat |
S P Kalra, M G Dube, P S Kalr. Continuous intraventricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats: effects of adrenalectomy and cholecystokinin. Peptides. vol 9. issue 4. 1989-04-04. PMID:3226950. |
concurrent infusion of cholecystokinin (cck) at either equimolar or 2.5 x npy dose, affected neither the npy-induced cumulative food intake nor any other parameter of feeding behavior. |
1989-04-04 |
2023-08-11 |
rat |
S P Kalra, M G Dube, P S Kalr. Continuous intraventricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats: effects of adrenalectomy and cholecystokinin. Peptides. vol 9. issue 4. 1989-04-04. PMID:3226950. |
on the other hand, cumulative food intake was significantly decreased in adrenalectomized rats in response to npy infusion (470 pmol/hr); a response due primarily to a marked suppression in some, and almost complete cessation of food consumption in other rats during the second 2 hr period of npy infusion. |
1989-04-04 |
2023-08-11 |
rat |
S P Kalra, M G Dube, P S Kalr. Continuous intraventricular infusion of neuropeptide Y evokes episodic food intake in satiated female rats: effects of adrenalectomy and cholecystokinin. Peptides. vol 9. issue 4. 1989-04-04. PMID:3226950. |
these studies show that continuous central infusion of npy can produce sustained, intermittent feeding behavior and adrenalectomy significantly curtailed the duration of npy effectiveness. |
1989-04-04 |
2023-08-11 |
rat |
A Sahu, S P Kalra, W R Crowley, P S Kalr. Evidence that NPY-containing neurons in the brainstem project into selected hypothalamic nuclei: implication in feeding behavior. Brain research. vol 457. issue 2. 1989-03-22. PMID:3219564. |
recent studies show that bilateral neural transections (nt) at the level of dorsal tegmentum in the mesencephalon significantly increase food intake and decrease latency to onset of feeding behavior in response to neuropeptide y (npy). |
1989-03-22 |
2023-08-11 |
rat |