| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Sahu, S P Kalra, W R Crowley, P S Kalr. Evidence that NPY-containing neurons in the brainstem project into selected hypothalamic nuclei: implication in feeding behavior. Brain research. vol 457. issue 2. 1989-03-22. PMID:3219564. |
the increased responsiveness to npy may be due to denervation-induced hypersensitivity to npy in hypothalamic sites that mediate feeding behavior in rats. |
1989-03-22 |
2023-08-11 |
rat |
| A Sahu, S P Kalra, W R Crowley, P S Kalr. Evidence that NPY-containing neurons in the brainstem project into selected hypothalamic nuclei: implication in feeding behavior. Brain research. vol 457. issue 2. 1989-03-22. PMID:3219564. |
these findings indicate that npy-containing neurons in the brainstem may project into selected hypothalamic sites and the reduction in the nt rats of npy levels, especially in the paraventricular nucleus, may be responsible for the reported increase in sensitivity of the npy-induced feeding response. |
1989-03-22 |
2023-08-11 |
rat |
| S P Kalra, J T Clark, A Sahu, M G Dube, P S Kalr. Control of feeding and sexual behaviors by neuropeptide Y: physiological implications. Synapse (New York, N.Y.). vol 2. issue 3. 1989-02-23. PMID:3212671. |
we observed that central administration of bolus npy stimulated a robust, dose-related feeding response in satiated male and female rats. |
1989-02-23 |
2023-08-11 |
rat |
| S P Kalra, J T Clark, A Sahu, M G Dube, P S Kalr. Control of feeding and sexual behaviors by neuropeptide Y: physiological implications. Synapse (New York, N.Y.). vol 2. issue 3. 1989-02-23. PMID:3212671. |
continuous npy receptor activation also evoked dose-related, intermittent feeding in a manner normally observed during nocturnal feeding. |
1989-02-23 |
2023-08-11 |
rat |
| S P Kalra, J T Clark, A Sahu, M G Dube, P S Kalr. Control of feeding and sexual behaviors by neuropeptide Y: physiological implications. Synapse (New York, N.Y.). vol 2. issue 3. 1989-02-23. PMID:3212671. |
it appears that the paraventricular nucleus in the hypothalamus may be the primary site of npy action because the anticipated reciprocal changes in npy concentrations, in response to food deprivation followed by ad libitum food intake, occurred only in this site. |
1989-02-23 |
2023-08-11 |
rat |
| S P Kalra, J T Clark, A Sahu, M G Dube, P S Kalr. Control of feeding and sexual behaviors by neuropeptide Y: physiological implications. Synapse (New York, N.Y.). vol 2. issue 3. 1989-02-23. PMID:3212671. |
the suppressive effects on sexual behavior were apparent prior to or at the time of the onset of feeding after npy administration. |
1989-02-23 |
2023-08-11 |
rat |
| J T Clark, R S Gist, S P Kalra, P S Kalr. Alpha 2-adrenoceptor blockade attenuates feeding behavior induced by neuropeptide Y and epinephrine. Physiology & behavior. vol 43. issue 4. 1989-01-11. PMID:2904155. |
neuropeptide y (npy, 0.47 nmol) and epinephrine (28.9 nmol) evoked robust, and quantitatively similar, increments in food intake and local eating rate following administration into the third cerebral ventricle (iiiv). |
1989-01-11 |
2023-08-11 |
Not clear |
| J T Clark, R S Gist, S P Kalra, P S Kalr. Alpha 2-adrenoceptor blockade attenuates feeding behavior induced by neuropeptide Y and epinephrine. Physiology & behavior. vol 43. issue 4. 1989-01-11. PMID:2904155. |
whereas iiiv pretreatment with phentolamine (71 nmol), a nonselective alpha-adrenoceptor antagonist, or prazosin (9.5 nmol), a selective alpha 1-adrenoceptor antagonist, was without effect on npy-induced feeding behavior, pretreatment with the alpha 2-adrenoceptor antagonist yohimbine (15 nmol) dramatically attenuated the stimulatory effects of npy or epinephrine on both food intake (by over 50%) and local eating rate. |
1989-01-11 |
2023-08-11 |
Not clear |
| J T Clark, R S Gist, S P Kalra, P S Kalr. Alpha 2-adrenoceptor blockade attenuates feeding behavior induced by neuropeptide Y and epinephrine. Physiology & behavior. vol 43. issue 4. 1989-01-11. PMID:2904155. |
these data demonstrate that feeding behavior induced by iiiv administration of npy or epinephrine is attenuated by prior blockade of alpha 2-adrenoceptors and suggest that, as in other systems innervated by neurons displaying npy and adrenergic transmitter colocalization, the effects of npy on feeding behavior may, at least in part, be mediated via alpha 2-adrenoceptors. |
1989-01-11 |
2023-08-11 |
Not clear |
| A Sahu, P S Kalra, S P Kalr. Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus. Peptides. vol 9. issue 1. 1988-05-31. PMID:3362745. |
in contrast, in the pvn, a site implicated in the control of feeding behavior, the npy response to fd and fi was markedly different. |
1988-05-31 |
2023-08-11 |
rat |
| W J Kuenzel, L W Douglass, B A Daviso. Robust feeding following central administration of neuropeptide Y or peptide YY in chicks, Gallus domesticus. Peptides. vol 8. issue 5. 1988-03-02. PMID:3432131. |
both npy and pyy markedly increased food intake during the first hour post-injection compared to saline (sal) controls. |
1988-03-02 |
2023-08-11 |
Not clear |
| W J Kuenzel, L W Douglass, B A Daviso. Robust feeding following central administration of neuropeptide Y or peptide YY in chicks, Gallus domesticus. Peptides. vol 8. issue 5. 1988-03-02. PMID:3432131. |
food intake doubled in chicks given 5 micrograms npy. |
1988-03-02 |
2023-08-11 |
Not clear |
| W J Kuenzel, L W Douglass, B A Daviso. Robust feeding following central administration of neuropeptide Y or peptide YY in chicks, Gallus domesticus. Peptides. vol 8. issue 5. 1988-03-02. PMID:3432131. |
a response surface analysis suggested that following icv injection of npy, maximum food intake occurred, using a dose of 9 micrograms. |
1988-03-02 |
2023-08-11 |
Not clear |
| J E Morley, E N Hernandez, J F Floo. Neuropeptide Y increases food intake in mice. The American journal of physiology. vol 253. issue 3 Pt 2. 1987-10-22. PMID:3631310. |
human npy also increased food intake, whereas the free acid of npy was inactive. |
1987-10-22 |
2023-08-11 |
mouse |
| J E Morley, E N Hernandez, J F Floo. Neuropeptide Y increases food intake in mice. The American journal of physiology. vol 253. issue 3 Pt 2. 1987-10-22. PMID:3631310. |
although some minor discrepancies in response were noted overall, npy was as effective at stimulating food intake in genetically obese (ob/ob) mice compared with their lean littermates (ob/-), in genetically diabetic mice (db/db) and their nondiabetic heterozygote control (db/m), in streptozocin-induced diabetic mice and their controls, and in adult (8 mo old) compared with old (25 mo old) mice. |
1987-10-22 |
2023-08-11 |
mouse |
| J L Steinman, D G Fujikawa, C G Wasterlain, A Cherkin, J E Morle. The effects of adrenergic, opioid and pancreatic polypeptidergic compounds on feeding and other behaviors in neonatal leghorn chicks. Peptides. vol 8. issue 4. 1987-10-21. PMID:2888097. |
the present study examined the effects of intracerebral (ic) administration of pancreatic polypeptide (pp), neuropeptide y (npy), norepinephrine (ne), dynorphin and naloxone on food intake in 2-day-old leghorn chicks. |
1987-10-21 |
2023-08-11 |
Not clear |
| J L Steinman, D G Fujikawa, C G Wasterlain, A Cherkin, J E Morle. The effects of adrenergic, opioid and pancreatic polypeptidergic compounds on feeding and other behaviors in neonatal leghorn chicks. Peptides. vol 8. issue 4. 1987-10-21. PMID:2888097. |
however, for those chicks which did not exhibit behavioral convulsions, food intake appeared to be elevated by 1, 5 and 10 micrograms of npy. |
1987-10-21 |
2023-08-11 |
Not clear |
| J L Steinman, D G Fujikawa, C G Wasterlain, A Cherkin, J E Morle. The effects of adrenergic, opioid and pancreatic polypeptidergic compounds on feeding and other behaviors in neonatal leghorn chicks. Peptides. vol 8. issue 4. 1987-10-21. PMID:2888097. |
similarly, ne did not elevate food intake but instead induced sedation and narcolepsy, a behavioral response which could be distinguished from the convulsions observed after npy. |
1987-10-21 |
2023-08-11 |
Not clear |
| N Sakatani, A Inui, T Inoue, M Oya, H Morioka, S Bab. The role of cholecystokinin octapeptide in the central control of food intake in the dog. Peptides. vol 8. issue 4. 1987-10-21. PMID:3306623. |
neuropeptide y (npy, 1, 190 pmol) had no significant stimulatory effect on food intake and water consumption in fasted as well as satiated dogs, and actually reduced both food and water intake in insulin-treated dogs. |
1987-10-21 |
2023-08-11 |
dog |
| N Sakatani, A Inui, T Inoue, M Oya, H Morioka, S Bab. The role of cholecystokinin octapeptide in the central control of food intake in the dog. Peptides. vol 8. issue 4. 1987-10-21. PMID:3306623. |
these results suggest that the effect of cck-8 on feeding seems to involve central mechanisms in the dog, and that the mechanisms by which cck-8, npy and naloxone affect feeding behavior are different. |
1987-10-21 |
2023-08-11 |
dog |