| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A J Sipols, D J Brief, K L Ginter, S Saghafi, S C Wood. Neuropeptide Y paradoxically increases food intake yet causes conditioned flavor aversions. Physiology & behavior. vol 51. issue 6. 1992-08-28. PMID:1641427. |
we now report that npy, at doses that stimulate food intake when administered intraventricularly, also causes the formation of robust conditioned flavor aversions when given via the same cannula and at the same dose. |
1992-08-28 |
2023-08-11 |
Not clear |
| D C Jewett, J Cleary, A S Levine, D W Schaal, T Thompso. Effects of neuropeptide Y on food-reinforced behavior in satiated rats. Pharmacology, biochemistry, and behavior. vol 42. issue 2. 1992-08-17. PMID:1631179. |
the effect of npy on behavior and food intake of food-satiated rats was examined under three different food availability conditions. |
1992-08-17 |
2023-08-11 |
rat |
| D C Jewett, J Cleary, A S Levine, D W Schaal, T Thompso. Effects of neuropeptide Y on food-reinforced behavior in satiated rats. Pharmacology, biochemistry, and behavior. vol 42. issue 2. 1992-08-17. PMID:1631179. |
npy (5 micrograms) significantly increased food intake under all conditions and increased food-reinforced responses under the fr and fi schedules. |
1992-08-17 |
2023-08-11 |
rat |
| D C Jewett, J Cleary, A S Levine, D W Schaal, T Thompso. Effects of neuropeptide Y on food-reinforced behavior in satiated rats. Pharmacology, biochemistry, and behavior. vol 42. issue 2. 1992-08-17. PMID:1631179. |
npy's effect on food intake was greatest when food was freely available and least for rats working under the schedule requiring the most effort (fr 40). |
1992-08-17 |
2023-08-11 |
rat |
| D C Jewett, J Cleary, A S Levine, D W Schaal, T Thompso. Effects of neuropeptide Y on food-reinforced behavior in satiated rats. Pharmacology, biochemistry, and behavior. vol 42. issue 2. 1992-08-17. PMID:1631179. |
food intake peaked after 3 days under repeated daily administration of npy. |
1992-08-17 |
2023-08-11 |
rat |
| D C Jewett, J Cleary, A S Levine, D W Schaal, T Thompso. Effects of neuropeptide Y on food-reinforced behavior in satiated rats. Pharmacology, biochemistry, and behavior. vol 42. issue 2. 1992-08-17. PMID:1631179. |
these data show npy substantially increases food-maintained behavior and is a potent inducer of food intake even under conditions where considerable effort is required to obtain food. |
1992-08-17 |
2023-08-11 |
rat |
| D C Jewett, J Cleary, A S Levine, D W Schaal, T Thompso. Effects of neuropeptide Y on food-reinforced behavior in satiated rats. Pharmacology, biochemistry, and behavior. vol 42. issue 2. 1992-08-17. PMID:1631179. |
further, the conditions under which food is made available can dramatically alter npy's effect on the temporal pattern of food-maintained responding, feeding, and latency to eat. |
1992-08-17 |
2023-08-11 |
rat |
| H Herzog, Y J Hort, H J Ball, G Hayes, J Shine, L A Selbi. Cloned human neuropeptide Y receptor couples to two different second messenger systems. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 13. 1992-08-14. PMID:1321422. |
neuropeptide y (npy) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiological activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. |
1992-08-14 |
2023-08-11 |
human |
| S E Kyrkouli, B G Stanley, S F Leibowit. Differential effects of galanin and neuropeptide Y on extracellular norepinephrine levels in the paraventricular hypothalamic nucleus of the rat: a microdialysis study. Life sciences. vol 51. issue 3. 1992-07-28. PMID:1377322. |
evidence suggests that the peptides galanin (gal) and neuropeptide y (npy) interact with the amine norepinephrine (ne) in the hypothalamic paraventricular nucleus (pvn) to stimulate feeding behavior. |
1992-07-28 |
2023-08-11 |
rat |
| S E Kyrkouli, B G Stanley, S F Leibowit. Differential effects of galanin and neuropeptide Y on extracellular norepinephrine levels in the paraventricular hypothalamic nucleus of the rat: a microdialysis study. Life sciences. vol 51. issue 3. 1992-07-28. PMID:1377322. |
following pvn administration of gal (0.3 nmol), npy (78 pmol) or ringer's solution, local ne levels were measured at 20-min intervals for 2 hrs postinjection, under two feeding conditions, namely, in the presence or absence of food. |
1992-07-28 |
2023-08-11 |
rat |
| B Beck, A Stricker-Krongrad, J P Nicolas, C Burle. Chronic and continuous intracerebroventricular infusion of neuropeptide Y in Long-Evans rats mimics the feeding behaviour of obese Zucker rats. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 16. issue 4. 1992-07-14. PMID:1318284. |
neuropeptide y (npy), a member of the pancreatic polypeptide family, strongly stimulates food intake when injected centrally in animals. |
1992-07-14 |
2023-08-11 |
rat |
| B Beck, A Stricker-Krongrad, J P Nicolas, C Burle. Chronic and continuous intracerebroventricular infusion of neuropeptide Y in Long-Evans rats mimics the feeding behaviour of obese Zucker rats. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 16. issue 4. 1992-07-14. PMID:1318284. |
we therefore continuously infused npy in the brain lateral ventricle through osmotic mini-pumps and studied the effects of this infusion on different parameters of the feeding behaviour. |
1992-07-14 |
2023-08-11 |
rat |
| B Beck, A Stricker-Krongrad, J P Nicolas, C Burle. Chronic and continuous intracerebroventricular infusion of neuropeptide Y in Long-Evans rats mimics the feeding behaviour of obese Zucker rats. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 16. issue 4. 1992-07-14. PMID:1318284. |
total food intake markedly increased in npy infused rats starting on the first day after pump installation (33.7 +/- 1.7 vs. 14.8 +/- 0.6 g/day; p less than 0.0001). |
1992-07-14 |
2023-08-11 |
rat |
| M W Schwartz, A J Sipols, J L Marks, G Sanacora, J D White, A Scheurink, S E Kahn, D G Baskin, S C Woods, D P Figlewic. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology. vol 130. issue 6. 1992-07-06. PMID:1597158. |
insulin acts in the brain to suppress feeding, whereas neuropeptide y (npy) has the opposite effect. |
1992-07-06 |
2023-08-11 |
rat |
| M Heilig, L Edvinsson, C Wahlested. Effects of intracerebroventricular D-myo-inositol-1,2,6-trisphosphate (PP56), a proposed neuropeptide Y (NPY) antagonist, on locomotor activity, food intake, central effects of NPY and NPY-receptor binding. European journal of pharmacology. vol 209. issue 1-2. 1992-06-23. PMID:1667639. |
effects of intracerebroventricular d-myo-inositol-1,2,6-trisphosphate (pp56), a proposed neuropeptide y (npy) antagonist, on locomotor activity, food intake, central effects of npy and npy-receptor binding. |
1992-06-23 |
2023-08-11 |
rat |
| M Heilig, L Edvinsson, C Wahlested. Effects of intracerebroventricular D-myo-inositol-1,2,6-trisphosphate (PP56), a proposed neuropeptide Y (NPY) antagonist, on locomotor activity, food intake, central effects of NPY and NPY-receptor binding. European journal of pharmacology. vol 209. issue 1-2. 1992-06-23. PMID:1667639. |
pp56 on locomotor activity and food intake in rats, and on the hypoactivity and hyperphagia induced by npy. |
1992-06-23 |
2023-08-11 |
rat |
| S F Leibowitz, J T Alexande. Analysis of neuropeptide Y-induced feeding: dissociation of Y1 and Y2 receptor effects on natural meal patterns. Peptides. vol 12. issue 6. 1992-06-22. PMID:1667688. |
to differentiate npy receptor subtypes, y1 and y2, in terms of their impact on feeding behavior, the intact molecule npy(1-36) and the 3 fragments, npy(2-36), the y1 agonist [leu31,pro34]npy, and the y2 agonist npy(13-36), were injected (100 pmol/0.3 microliters) into the hypothalamic paraventricular nucleus (pvn) of freely feeding rats. |
1992-06-22 |
2023-08-11 |
rat |
| S F Leibowitz, J T Alexande. Analysis of neuropeptide Y-induced feeding: dissociation of Y1 and Y2 receptor effects on natural meal patterns. Peptides. vol 12. issue 6. 1992-06-22. PMID:1667688. |
the results demonstrate that: 1) npy(1-36) potentiates feeding behavior, primarily carbohydrate ingestion, by increasing the size and duration of the first meal after injection, rather than by affecting meal number of feeding rate, suggesting that npy acts through mechanisms of satiety. |
1992-06-22 |
2023-08-11 |
rat |
| A Balasubramaniam, D F Rigel, W T Chance, J E Fische. Central and peripheral effects of sculpin pancreatic polypeptide and anglerfish peptide Y in rats. Peptide research. vol 5. issue 2. 1992-06-16. PMID:1581637. |
these investigations revealed that both peptides, like npy, increased blood pressure and induced feeding in rats, presumably by interacting with receptors of npy. |
1992-06-16 |
2023-08-11 |
rat |
| J L Mine. Recent advances in the central control of intake in ruminants. Journal of animal science. vol 70. issue 4. 1992-06-16. PMID:1582957. |
even so, these satiating factors are able to reduce feeding in the face of at least one dosage of exogenous npy. |
1992-06-16 |
2023-08-11 |
rat |