| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B G Stanley, W Magdalin, A Seirafi, W J Thomas, S F Leibowit. The perifornical area: the major focus of (a) patchily distributed hypothalamic neuropeptide Y-sensitive feeding system(s). Brain research. vol 604. issue 1-2. 1993-04-26. PMID:8457858. |
to delineate precisely the locus of this effect, npy (78 pmol) or its artificial cerebrospinal fluid vehicle was injected in the extremely small volume of 10 nl through chronic guide cannulae into an array of 47 different hypothalamic areas in satiated rats and the elicited food intake was measured. |
1993-04-26 |
2023-08-12 |
rat |
| B G Stanley, W Magdalin, A Seirafi, W J Thomas, S F Leibowit. The perifornical area: the major focus of (a) patchily distributed hypothalamic neuropeptide Y-sensitive feeding system(s). Brain research. vol 604. issue 1-2. 1993-04-26. PMID:8457858. |
npy there elicited mean increases in food intake of 12.5 g over baseline at 1 h and 20.0 g at 4 h postinjection. |
1993-04-26 |
2023-08-12 |
rat |
| H C Walker, D R Romso. Similar effects of NPY on energy metabolism and on plasma insulin in adrenalectomized ob/ob and lean mice. The American journal of physiology. vol 264. issue 2 Pt 1. 1993-04-02. PMID:8447389. |
further, intracerebroventricular npy increased food intake equally in both ob/ob and lean mice, whereas dexamethasone did not alter food intake during the 30 min postinjection period. |
1993-04-02 |
2023-08-12 |
mouse |
| U Pesonen, R Huupponen, J Rouru, M Koul. Hypothalamic neuropeptide expression after food restriction in Zucker rats: evidence of persistent neuropeptide Y gene activation. Brain research. Molecular brain research. vol 16. issue 3-4. 1993-04-01. PMID:1363327. |
the results suggest that orexigenic npy plays a role in the adaptation to altered feeding status. |
1993-04-01 |
2023-08-11 |
rat |
| T Shibasaki, T Oda, T Imaki, N Ling, H Demur. Injection of anti-neuropeptide Y gamma-globulin into the hypothalamic paraventricular nucleus decreases food intake in rats. Brain research. vol 601. issue 1-2. 1993-03-17. PMID:7679310. |
the effect of immunoneutralization of hypothalamic neuropeptide y (npy) on food intake was examined to clarify the involvement of npy in the control mechanism of feeding behavior. |
1993-03-17 |
2023-08-12 |
rat |
| T Shibasaki, T Oda, T Imaki, N Ling, H Demur. Injection of anti-neuropeptide Y gamma-globulin into the hypothalamic paraventricular nucleus decreases food intake in rats. Brain research. vol 601. issue 1-2. 1993-03-17. PMID:7679310. |
this result suggests that npy in the paraventricular nucleus plays a role in stimulating feeding behavior. |
1993-03-17 |
2023-08-12 |
rat |
| N Pages, M Orosco, C Rouch, O Yao, C Jacquot, C Bohuo. Fasting affects more markedly neuropeptide Y than monoamines in the rat brain. Pharmacology, biochemistry, and behavior. vol 44. issue 1. 1993-03-09. PMID:7679221. |
no relationship appeared between npy and monoamine levels, suggesting that npy can act independently in feeding behavior and play, in different brain areas, an important role in its regulation. |
1993-03-09 |
2023-08-12 |
rat |
| S F Leibowitz, M Xuereb, T Ki. Blockade of natural and neuropeptide Y-induced carbohydrate feeding by a receptor antagonist PYX-2. Neuroreport. vol 3. issue 11. 1993-02-16. PMID:1482761. |
they also constitute a crucial step in demonstrating a physiological function of these pvn npy receptors specifically in controlling carbohydrate ingestion at the onset of the natural feeding cycle. |
1993-02-16 |
2023-08-11 |
rat |
| S C Heinrichs, B J Cole, E M Pich, F Menzaghi, G F Koob, R L Hauge. Endogenous corticotropin-releasing factor modulates feeding induced by neuropeptide Y or a tail-pinch stressor. Peptides. vol 13. issue 5. 1993-02-09. PMID:1480513. |
the present experiments examined the effects of exogenously administered crf and a crf antagonist, alpha-helical crf(9-41), on spontaneous feeding induced by neuropeptide y (npy) and by a tail-pinch stressor. |
1993-02-09 |
2023-08-11 |
Not clear |
| S C Heinrichs, B J Cole, E M Pich, F Menzaghi, G F Koob, R L Hauge. Endogenous corticotropin-releasing factor modulates feeding induced by neuropeptide Y or a tail-pinch stressor. Peptides. vol 13. issue 5. 1993-02-09. PMID:1480513. |
hence, while crf administration impairs intake in these and other feeding paradigms, alpha-hel crf actually facilitated dose dependently the intensity of the feeding response to npy and tail pinch. |
1993-02-09 |
2023-08-11 |
Not clear |
| C Catzeflis, D D Pierroz, F Rohner-Jeanrenaud, J E Rivier, P C Sizonenko, M L Auber. Neuropeptide Y administered chronically into the lateral ventricle profoundly inhibits both the gonadotropic and the somatotropic axis in intact adult female rats. Endocrinology. vol 132. issue 1. 1993-02-05. PMID:8380374. |
whereas central administration of npy strongly stimulates feeding in satiated animals, diet restriction produces overexpression of npy in the arcuate and paraventricular nuclei that might reflect behavioral adaptations to shortage of food. |
1993-02-05 |
2023-08-12 |
rat |
| C Catzeflis, D D Pierroz, F Rohner-Jeanrenaud, J E Rivier, P C Sizonenko, M L Auber. Neuropeptide Y administered chronically into the lateral ventricle profoundly inhibits both the gonadotropic and the somatotropic axis in intact adult female rats. Endocrinology. vol 132. issue 1. 1993-02-05. PMID:8380374. |
chronic icv infusion of npy produced the expected dose-related increase in food intake [25.3 +/- 0.8 g/day (basal) to 47.9 +/- 4.3 g/day (highest npy dose)] and body wt gain (3.7 +/- 0.4-11.5 +/- 1.4 g/day). |
1993-02-05 |
2023-08-12 |
rat |
| M G Dube, A Sahu, C P Phelps, P S Kalra, S P Kalr. Effect of d-fenfluramine on neuropeptide Y concentration and release in the paraventricular nucleus of food-deprived rats. Brain research bulletin. vol 29. issue 6. 1993-02-03. PMID:1473018. |
recent evidence indicates that neuropeptide y (npy) is an important signal in the hypothalamic neural circuitry that stimulates feeding in the rat. |
1993-02-03 |
2023-08-11 |
rat |
| R D Myers, M F Lankford, X Pae. Norepinephrine, dopamine, and 5-HT release from perfused hypothalamus of the rat during feeding induced by neuropeptide Y. Neurochemical research. vol 17. issue 11. 1993-01-08. PMID:1461360. |
although control perfusions were without effect on feeding or monoamine activity, npy evoked mean cumulative intakes of food of 14 +/- 2.4, 25.6 +/- 3.0 and 26.5 +/- 3.2 g in response to 10, 50, or 100 ng/microliter concentrations of npy, respectively, over the 4.0-5.0 hr test interval. |
1993-01-08 |
2023-08-11 |
rat |
| R D Myers, M F Lankford, X Pae. Norepinephrine, dopamine, and 5-HT release from perfused hypothalamus of the rat during feeding induced by neuropeptide Y. Neurochemical research. vol 17. issue 11. 1993-01-08. PMID:1461360. |
however, neither the basal efflux of 5-ht nor its turnover, as reflected by the output of 5-hiaa, was affected during feeding induced by npy perfused in the hypothalamus. |
1993-01-08 |
2023-08-11 |
rat |
| A Sahu, C A Sninsky, C P Phelps, M G Dube, P S Kalra, S P Kalr. Neuropeptide Y release from the paraventricular nucleus increases in association with hyperphagia in streptozotocin-induced diabetic rats. Endocrinology. vol 131. issue 6. 1992-12-30. PMID:1446635. |
since npy is the most potent naturally occurring orexigenic signal and the pvn is an important initial site of npy action in the stimulatory pathway regulating feeding, our findings of augmented pvn npy release in vivo and in vitro are in accord with the hypothesis that increased npy secretion in the pvn may be responsible for hyperphagia in diabetic rats. |
1992-12-30 |
2023-08-11 |
rat |
| J A Ober, P V Malve. Effect of growth retardation on pituitary luteinizing hormone and hypothalamic neuropeptide Y in ovariectomized sheep. Neuroendocrinology. vol 56. issue 3. 1992-12-22. PMID:1436372. |
the possible role of neuropeptide y (npy) in mediating the relationship between pituitary lh secretion and growth retardation due to restricted feeding was examined in ovariectomized (ovx) prepubertal ewe lambs. |
1992-12-22 |
2023-08-11 |
Not clear |
| R A Galbraith, S C Chua, A Kappa. Hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: inhibition of the feeding response to NPY. Brain research. Molecular brain research. vol 15. issue 3-4. 1992-12-14. PMID:1331684. |
hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: inhibition of the feeding response to npy. |
1992-12-14 |
2023-08-11 |
rat |
| R A Galbraith, S C Chua, A Kappa. Hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: inhibition of the feeding response to NPY. Brain research. Molecular brain research. vol 15. issue 3-4. 1992-12-14. PMID:1331684. |
neuropeptide y (npy) is a known endogenous stimulator of feeding behavior and is elevated in the hypothalamus of food-deprived rats. |
1992-12-14 |
2023-08-11 |
rat |
| R A Galbraith, S C Chua, A Kappa. Hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: inhibition of the feeding response to NPY. Brain research. Molecular brain research. vol 15. issue 3-4. 1992-12-14. PMID:1331684. |
concentrations of npy mrna in the hypothalami of rats treated intracerebroventricularly with vehicle or copp responded to decreased food intake with comparable increases. |
1992-12-14 |
2023-08-11 |
rat |