| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Inés Ibarra-Lecue, Fuencisla Pilar-Cuéllar, Carolina Muguruza, Eva Florensa-Zanuy, Álvaro Díaz, Leyre Urigüen, Elena Castro, Angel Pazos, Luis F Callad. The endocannabinoid system in mental disorders: Evidence from human brain studies. Biochemical pharmacology. vol 157. 2019-07-08. PMID:30026022. |
studies carried out in humans have consistently demonstrated that the endocannabinoid system is fundamental for emotional homeostasis and cognitive function. |
2019-07-08 |
2023-08-13 |
human |
| Brenda Sbarski, Irit Akira. Chronic exposure to cannabinoids before an emotional trauma may have negative effects on emotional function. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 8. 2019-04-30. PMID:30026011. |
chronic exposure to cannabinoids before an emotional trauma may have negative effects on emotional function. |
2019-04-30 |
2023-08-13 |
rat |
| Brenda Sbarski, Irit Akira. Chronic exposure to cannabinoids before an emotional trauma may have negative effects on emotional function. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 8. 2019-04-30. PMID:30026011. |
chronic exposure to cannabinoids prior to an emotional trauma may have deleterious effects on emotional function suggesting that direct cb1/2 receptor activation may not be an optimal way to manipulate the endocannabinoid system in stressful individuals. |
2019-04-30 |
2023-08-13 |
rat |
| Lisa Wirz, Martin Reuter, Andrea Felten, Lars Schwab. An endocannabinoid receptor polymorphism modulates affective processing under stress. Social cognitive and affective neuroscience. vol 13. issue 11. 2019-04-22. PMID:30239920. |
based on rodent data suggesting that endocannabinoid signaling via cb1 receptors serves as an emotional buffer, we hypothesized that a common variant of the gene coding for the cb1 receptor modulates affective processing under stress (cnr1; rs1049353 a vs g allele). |
2019-04-22 |
2023-08-13 |
human |
| Lisa Wirz, Martin Reuter, Andrea Felten, Lars Schwab. An endocannabinoid receptor polymorphism modulates affective processing under stress. Social cognitive and affective neuroscience. vol 13. issue 11. 2019-04-22. PMID:30239920. |
these findings underline the modulatory role of the endocannabinoid system in stress effects on emotion and cognition and provide insights into the neural mechanisms that may contribute to the suggested protective effect of the aa/ag genotype of the cb1 receptor polymorphism against stress-related psychopathologies. |
2019-04-22 |
2023-08-13 |
human |
| Judit Lazary, Nora Eszlari, Gabriella Juhasz, Gyorgy Bagd. [Genetic association analyses of the endocannabinoid system on anxious phenotype]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 19. issue 4. 2019-04-16. PMID:29411704. |
accumulating data confirmed that the endocannabinoid system (ecs) is involved in the regulation of stress response and emotional processes, therefore ecs became an important pharmacological target as a potential anxiolytic. |
2019-04-16 |
2023-08-13 |
human |
| Zineb Ibn Lahmar Andaloussi, Khalid Taghzouti, Oualid Abbouss. Behavioural and epigenetic effects of paternal exposure to cannabinoids during adolescence on offspring vulnerability to stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 72. 2019-04-03. PMID:30476535. |
chronic cannabinoid exposure during adolescence in male rats induces chronic cognitive and emotional impairments. |
2019-04-03 |
2023-08-13 |
rat |
| Danica Bajic, Krisztina Monory, Andrea Conrad, Christina Maul, Roland M Schmid, Carsten T Wotjak, Christoph K Stein-Thoeringe. Cannabinoid Receptor Type 1 in the Brain Regulates the Affective Component of Visceral Pain in Mice. Neuroscience. vol 384. 2019-02-21. PMID:29885522. |
as the endocannabinoid system regulates affect and emotional behaviors, we hypothesized that cerebral cb1 influences affective processing of visceral pain-related behaviors in laboratory animals. |
2019-02-21 |
2023-08-13 |
mouse |
| Marta Portero-Tresserra, Irene Gracia-Rubio, Lídia Cantacorps, Oscar J Pozo, Alejandro Gómez-Gómez, Antoni Pastor, Raúl López-Arnau, Rafael de la Torre, Olga Valverd. Maternal separation increases alcohol-drinking behaviour and reduces endocannabinoid levels in the mouse striatum and prefrontal cortex. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 4. 2019-02-11. PMID:29478745. |
results showed that msew mice presented emotional alterations related to depressive-like behaviour and modified endocannabinoid levels in the striatum and the prefrontal cortex. |
2019-02-11 |
2023-08-13 |
mouse |
| Luke John Ney, Allison Matthews, Raimondo Bruno, Kim Louise Felmingha. Modulation of the endocannabinoid system by sex hormones: Implications for posttraumatic stress disorder. Neuroscience and biobehavioral reviews. vol 94. 2019-02-11. PMID:30017748. |
recent preclinical developments have implicated the endocannabinoid system in stress responses, emotional memories and fear extinction, all critical to ptsd aetiology. |
2019-02-11 |
2023-08-13 |
Not clear |
| Anissa Bara, Antonia Manduca, Axel Bernabeu, Milene Borsoi, Michela Serviado, Olivier Lassalle, Michelle Murphy, Jim Wager-Miller, Ken Mackie, Anne-Laure Pelissier-Alicot, Viviana Trezza, Olivier J Manzon. Sex-dependent effects of in utero cannabinoid exposure on cortical function. eLife. vol 7. 2019-01-07. PMID:30201092. |
group 1 mglur and endocannabinoid signaling regulate emotional behavior and synaptic plasticity. |
2019-01-07 |
2023-08-13 |
rat |
| H Schoch, M Y Huerta, C M Ruiz, M R Farrell, K M Jung, J J Huang, R R Campbell, D Piomelli, S V Mahle. Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. Psychopharmacology. vol 235. issue 1. 2018-12-11. PMID:29022083. |
adolescence is characterized by endocannabinoid (ecb)-dependent refinement of neural circuits underlying emotion, learning, and motivation. |
2018-12-11 |
2023-08-13 |
rat |
| Dan Zhou, Yue Li, Tian Tian, Wei Quan, Lei Wang, Qing Shao, Lian-Qiang Fu, Xiao-Hong Zhang, Xiao-Ye Wang, Hui Zhang, Yan-Min M. Role of the endocannabinoid system in the formation and development of depression. Die Pharmazie. vol 72. issue 8. 2018-08-24. PMID:29441900. |
in addition, the endocannabinoid system (ecs) related to cb1 receptors may be involved in human emotion regulation, especially depression occurrence. |
2018-08-24 |
2023-08-13 |
human |
| Sheila Leone, Lucia Recinella, Annalisa Chiavaroli, Sara Martinotti, Claudio Ferrante, Adriano Mollica, Giorgia Macedonio, Azzurra Stefanucci, Szabolcs Dvorácskó, Csaba Tömböly, Luciano De Petrocellis, Michele Vacca, Luigi Brunetti, Giustino Orland. Emotional disorders induced by Hemopressin and RVD-hemopressin(α) administration in rats. Pharmacological reports : PR. vol 69. issue 6. 2018-07-27. PMID:29128806. |
the endocannabinoid (ecb) system plays an important role in regulating emotional disorders, and is involved, directly or indirectly, in psychiatric diseases, such as anxiety and depression. |
2018-07-27 |
2023-08-13 |
rat |
| C R Kasten, Y Zhang, S L Boeh. Acute and long-term effects of Δ9-tetrahydrocannabinol on object recognition and anxiety-like activity are age- and strain-dependent in mice. Pharmacology, biochemistry, and behavior. vol 163. 2018-07-10. PMID:29107728. |
use of exogenous cannabinoids disrupts the fine-tuned endocannabinoid receptor system, possibly leading to alterations in cognition, memory, and emotional processes that endure long after cannabinoid use has stopped. |
2018-07-10 |
2023-08-13 |
mouse |
| Erica Zamberletti, Marina Gabaglio, Daniela Parolar. The Endocannabinoid System and Autism Spectrum Disorders: Insights from Animal Models. International journal of molecular sciences. vol 18. issue 9. 2018-05-14. PMID:28880200. |
the endocannabinoid (ec) system represents a major neuromodulatory system involved in the regulation of emotional responses, behavioral reactivity to context, and social interaction. |
2018-05-14 |
2023-08-13 |
Not clear |
| Stephen G Woodhams, Victoria Chapman, David P Finn, Andrea G Hohmann, Volker Neugebaue. The cannabinoid system and pain. Neuropharmacology. vol 124. 2018-05-09. PMID:28625720. |
in this article, we review the role of an important endogenous pain control system, the endocannabinoid (ec) system, in the sensory, emotional, and cognitive aspects of pain. |
2018-05-09 |
2023-08-13 |
Not clear |
| Eric Murillo-Rodriguez, Jose Carlos Pastrana-Trejo, Mireille Salas-Crisóstomo, Miriel de-la-Cru. The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents. CNS & neurological disorders drug targets. vol 16. issue 4. 2018-04-16. PMID:28240187. |
the endocannabinoid system modulating levels of consciousness, emotions and likely dream contents. |
2018-04-16 |
2023-08-13 |
mouse |
| Eric Murillo-Rodriguez, Jose Carlos Pastrana-Trejo, Mireille Salas-Crisóstomo, Miriel de-la-Cru. The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents. CNS & neurological disorders drug targets. vol 16. issue 4. 2018-04-16. PMID:28240187. |
however, no solid evidence is available regarding the role of the endocannabinoid system in an unquestionable emotional component of the sleep: dream activity. |
2018-04-16 |
2023-08-13 |
mouse |
| Eric Murillo-Rodriguez, Jose Carlos Pastrana-Trejo, Mireille Salas-Crisóstomo, Miriel de-la-Cru. The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents. CNS & neurological disorders drug targets. vol 16. issue 4. 2018-04-16. PMID:28240187. |
since dreaming is a mental activity that occurs during sleep (characterized by emotions, sensory perceptions, and bizarre components) and the endocannabinoid system modulates neurobiological processes involving consciousness, such as learning and memory, attention, pain perception, emotions and sleep, it is acceptable to hypothesize that the endocannabinoid system might be modulating dream activity. |
2018-04-16 |
2023-08-13 |
mouse |