| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tiffany T-Y Lee, Boris B Gorzalk. Evidence for a Role of Adolescent Endocannabinoid Signaling in Regulating HPA Axis Stress Responsivity and Emotional Behavior Development. International review of neurobiology. vol 125. 2016-09-14. PMID:26638764. |
therefore, this review will focus on (1) the functionality of the adolescent hpa axis, (2) ecb regulation of the adult hpa axis, (3) dynamic changes in ecb signaling during the adolescent period, (4) the effects of adolescent stress exposure on the ecb system, and (5) modulation of hpa axis activity and emotional behavior by adolescent cannabinoid treatment. |
2016-09-14 |
2023-08-13 |
Not clear |
| Luca Carnevali, Federica Vacondio, Stefano Rossi, Sergio Callegari, Emilio Macchi, Gilberto Spadoni, Annalida Bedini, Silvia Rivara, Marco Mor, Andrea Sgoif. Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 11. 2016-08-26. PMID:26391492. |
mounting evidence suggests a role for endocannabinoid signaling in the regulation of both emotional behavior and cardiovascular function. |
2016-08-26 |
2023-08-13 |
human |
| Agnieszka A Kaczor, Katarzyna M Targowska-Duda, Jayendra Z Patel, Tuomo Laitinen, Teija Parkkari, Yahaya Adams, Tapio J Nevalainen, Antti Pos. Comparative molecular field analysis and molecular dynamics studies of α/β hydrolase domain containing 6 (ABHD6) inhibitors. Journal of molecular modeling. vol 21. issue 10. 2016-07-11. PMID:26350245. |
the endocannabinoid system remains an attractive molecular target for pharmacological intervention due to its roles in the central nervous system in learning, thinking, emotional function, regulation of food intake or pain sensation, as well as in the peripheral nervous system, where it modulates the action of cardiovascular, immune, metabolic or reproductive function. |
2016-07-11 |
2023-08-13 |
Not clear |
| Carmen La Porta, S Andreea Bura, Jone Llorente-Onaindia, Antoni Pastor, Francisco Navarrete, María Salud García-Gutiérrez, Rafael De la Torre, Jorge Manzanares, Jordi Monfort, Rafael Maldonad. Role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain. Pain. vol 156. issue 10. 2016-06-27. PMID:26067584. |
role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain. |
2016-06-27 |
2023-08-13 |
mouse |
| Carmen La Porta, S Andreea Bura, Jone Llorente-Onaindia, Antoni Pastor, Francisco Navarrete, María Salud García-Gutiérrez, Rafael De la Torre, Jorge Manzanares, Jordi Monfort, Rafael Maldonad. Role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain. Pain. vol 156. issue 10. 2016-06-27. PMID:26067584. |
in this study, we investigated the role of the endocannabinoid system (ecs) in the emotional and cognitive alterations associated with osteoarthritis pain. |
2016-06-27 |
2023-08-13 |
mouse |
| Priscila A Batista, Manoela V Fogaça, Francisco S Guimarãe. The endocannabinoid, endovanilloid and nitrergic systems could interact in the rat dorsolateral periaqueductal gray matter to control anxiety-like behaviors. Behavioural brain research. vol 293. 2016-06-02. PMID:26187694. |
cannabinoid compounds usually produce biphasic effects in the modulation of emotional responses. |
2016-06-02 |
2023-08-13 |
rat |
| Eva M Marco, Cinzia Rapino, Antonio Caprioli, Franco Borsini, Giovanni Laviola, Mauro Maccarron. Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety. PloS one. vol 10. issue 9. 2016-05-31. PMID:26360704. |
novel pharmacological targets have emerged in the recent years, and attention has focused on the endocannabinoid (ecb) system, given the increasing evidence that supports its central role in emotion, coping with stress and anxiety. |
2016-05-31 |
2023-08-13 |
mouse |
| Michael Loureiro, Justine Renard, Jordan Zunder, Steven R Laviolett. Hippocampal cannabinoid transmission modulates dopamine neuron activity: impact on rewarding memory formation and social interaction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 6. 2016-03-29. PMID:25510937. |
disturbances in cannabinoid type 1 receptor (cb1r) signaling have been linked to emotional and cognitive deficits characterizing neuropsychiatric disorders, including schizophrenia. |
2016-03-29 |
2023-08-13 |
rat |
| Mallory E Bowers, Kerry J Ressle. Interaction between the cholecystokinin and endogenous cannabinoid systems in cued fear expression and extinction retention. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 3. 2016-03-15. PMID:25176168. |
separate studies have implicated the cholecystokinin (cck) and endocannabinoid systems in fear; however, there is a high degree of anatomical colocalization between the cannabinoid 1 receptor (cnr1) and cck in the basolateral amygdala (bla), a brain region critical for emotion regulation. |
2016-03-15 |
2023-08-13 |
mouse |
| Paul Frenge. Inexpensive Complex Hand Model Twenty Years Later. Biomedical sciences instrumentation. vol 51. 2016-02-18. PMID:25996742. |
new artificial intelligence features included op-amp neurons for ocr and simulated emotions, hormone emulation, endocannabinoid receptors, fear-trust-love mechanisms, a grandmother cell recognizer and artificial consciousness. |
2016-02-18 |
2023-08-13 |
human |
| Maria Morena, Valentina De Castro, J Megan Gray, Maura Palmery, Viviana Trezza, Benno Roozendaal, Matthew N Hill, Patrizia Campolong. Training-Associated Emotional Arousal Shapes Endocannabinoid Modulation of Spatial Memory Retrieval in Rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 41. 2016-01-19. PMID:26468197. |
training-associated emotional arousal shapes endocannabinoid modulation of spatial memory retrieval in rats. |
2016-01-19 |
2023-08-13 |
rat |
| Ryan J McLaughlin, Matthew N Hill, Boris B Gorzalk. A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior. Neuroscience and biobehavioral reviews. vol 42. 2015-07-15. PMID:24582908. |
a critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior. |
2015-07-15 |
2023-08-12 |
Not clear |
| Ryan J McLaughlin, Matthew N Hill, Boris B Gorzalk. A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior. Neuroscience and biobehavioral reviews. vol 42. 2015-07-15. PMID:24582908. |
the endocannabinoid system has emerged as a fundamental regulator of hpa axis feedback inhibition and an important modulator of emotional behavior. |
2015-07-15 |
2023-08-12 |
Not clear |
| Maria Morena, Benno Roozendaal, Viviana Trezza, Patrizia Ratano, Andrea Peloso, Daniela Hauer, Piray Atsak, Luigia Trabace, Vincenzo Cuomo, James L McGaugh, Gustav Schelling, Patrizia Campolong. Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 51. 2015-04-17. PMID:25489086. |
endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. |
2015-04-17 |
2023-08-13 |
rat |
| Maria Morena, Benno Roozendaal, Viviana Trezza, Patrizia Ratano, Andrea Peloso, Daniela Hauer, Piray Atsak, Luigia Trabace, Vincenzo Cuomo, James L McGaugh, Gustav Schelling, Patrizia Campolong. Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 51. 2015-04-17. PMID:25489086. |
moreover, in support of the view that this emotional training-associated increase in endocannabinoid neurotransmission, and its effects on memory enhancement, depends on the integrity of functional interactions between these different brain regions, we found that disruption of bla activity blocked the training-induced increases in aea levels as well as the memory enhancement produced by urb597 administered into the hippocampus or mpfc. |
2015-04-17 |
2023-08-13 |
rat |
| Maria Morena, Benno Roozendaal, Viviana Trezza, Patrizia Ratano, Andrea Peloso, Daniela Hauer, Piray Atsak, Luigia Trabace, Vincenzo Cuomo, James L McGaugh, Gustav Schelling, Patrizia Campolong. Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 51. 2015-04-17. PMID:25489086. |
thus, the findings provide evidence that emotionally arousing training increases aea levels within prefrontal-limbic circuits and strongly suggest that this cannabinoid activation regulates emotional arousal effects on memory consolidation. |
2015-04-17 |
2023-08-13 |
rat |
| Eleonora Caroti, Valentina Cuoco, Michela Marconi, Flavia Ratti, Giuseppe Bersan. [The endocannabinoid system and its possible role in neurobiology of psychiatric disorders]. Rivista di psichiatria. vol 48. issue 5. 2015-04-06. PMID:24326750. |
analysing this property during preclinical studies, it came out that the endocannabinoid system is involved in numerous physiologic processes, such as neuroendocrine axes, food consumption, brain reward and satisfaction mechanisms, memories storing and extinction, emotions and neurodevelopment regulation. |
2015-04-06 |
2023-08-12 |
Not clear |
| Antonia Manduca, Michela Servadio, Patrizia Campolongo, Maura Palmery, Luigia Trabace, Louk J M J Vanderschuren, Vincenzo Cuomo, Viviana Trezz. Strain- and context-dependent effects of the anandamide hydrolysis inhibitor URB597 on social behavior in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 8. 2015-03-30. PMID:24933531. |
genetic and environmental factors play an important role in the cannabinoid modulation of motivation and emotion. |
2015-03-30 |
2023-08-13 |
rat |
| Carola Schaefer, Frank Enning, Juliane K Mueller, J Malte Bumb, Cathrin Rohleder, Thorsten M Odorfer, Joachim Klosterkötter, Martin Hellmich, Dagmar Koethe, Christian Schmahl, Martin Bohus, F Markus Lewek. Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. European archives of psychiatry and clinical neuroscience. vol 264. issue 5. 2015-03-09. PMID:24253425. |
the disorders frequently co-occur and often result in pervasive problems in, e.g., emotion regulation and altered pain perception, where the endocannabinoid system is deeply involved. |
2015-03-09 |
2023-08-12 |
Not clear |
| Giovanni Battistella, Eleonora Fornari, Jean-Marie Annoni, Haithem Chtioui, Kim Dao, Marie Fabritius, Bernard Favrat, Jean-Frédéric Mall, Philippe Maeder, Christian Girou. Long-term effects of cannabis on brain structure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 9. 2015-03-02. PMID:24633558. |
we provide evidence that regular cannabis use is associated with gray matter volume reduction in the medial temporal cortex, temporal pole, parahippocampal gyrus, insula, and orbitofrontal cortex; these regions are rich in cannabinoid cb1 receptors and functionally associated with motivational, emotional, and affective processing. |
2015-03-02 |
2023-08-12 |
Not clear |