| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leyre Urigüen, Fernando Berrendero, Catherine Ledent, Rafael Maldonado, Jorge Manzanare. Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice. The European journal of neuroscience. vol 22. issue 8. 2005-12-15. PMID:16262648. |
this endogenous interaction between opioid and cannabinoid receptors may be relevant to further understand a variety of neuroadaptative processes involving the participation of opioid receptors, such as motor behaviour, emotional responses and drug dependence. |
2005-12-15 |
2023-08-12 |
mouse |
| M P Viveros, Eva M Marco, Sandra E Fil. Endocannabinoid system and stress and anxiety responses. Pharmacology, biochemistry, and behavior. vol 81. issue 2. 2005-09-08. PMID:15927244. |
thus, the endocannabinoid system appears to play a pivotal role in the regulation of emotional states and may constitute a novel pharmacological target for anti-anxiety therapy. |
2005-09-08 |
2023-08-12 |
mouse |
| Fernando Rodríguez de Fonseca, Ignacio Del Arco, Francisco Javier Bermudez-Silva, Ainhoa Bilbao, Andrea Cippitelli, Miguel Navarr. The endocannabinoid system: physiology and pharmacology. Alcohol and alcoholism (Oxford, Oxfordshire). vol 40. issue 1. 2005-08-31. PMID:15550444. |
they bind to a family of g-protein-coupled receptors, of which the cannabinoid cb(1) receptor is densely distributed in areas of the brain related to motor control, cognition, emotional responses, motivated behaviour and homeostasis. |
2005-08-31 |
2023-08-12 |
Not clear |
| F Gambi, D De Berardis, G Sepede, R Quartesan, E Calcagni, R M Salerno, C M Conti, F M Ferr. Cannabinoid receptors and their relationships with neuropsychiatric disorders. International journal of immunopathology and pharmacology. vol 18. issue 1. 2005-07-14. PMID:15698507. |
the central effects of exogenous cannabinoids are implicated in enhancing mood, altering emotional states, and interfering in the formation of short-term memory. |
2005-07-14 |
2023-08-12 |
Not clear |
| Sachin Patel, Benjamin F Cravatt, Cecilia J Hillar. Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 3. 2005-04-21. PMID:15280883. |
these data suggest the cea is an important neural substrate subserving the interactions between cannabinoids and environmental stress, and could be relevant to understanding the context-dependent emotional and affective changes induced by marijuana intoxication and the role of endocannabinoid signaling in the modulation of amygdalar activity. |
2005-04-21 |
2023-08-12 |
mouse |
| Guy Griebel, Jeanne Stemmelin, Bernard Scatto. Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents. Biological psychiatry. vol 57. issue 3. 2005-04-01. PMID:15691527. |
effects of the cannabinoid cb1 receptor antagonist rimonabant in models of emotional reactivity in rodents. |
2005-04-01 |
2023-08-12 |
Not clear |
| Guy Griebel, Jeanne Stemmelin, Bernard Scatto. Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents. Biological psychiatry. vol 57. issue 3. 2005-04-01. PMID:15691527. |
the endocannabinoid system has been implicated in the modulation of emotional processes. |
2005-04-01 |
2023-08-12 |
Not clear |
| Andrea Giuffrida, F Markus Leweke, Christoph W Gerth, Daniela Schreiber, Dagmar Koethe, Johannes Faulhaber, Joachim Klosterkötter, Daniele Piomell. Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 11. 2005-01-11. PMID:15354183. |
the endocannabinoids are a family of bioactive lipids that activate cb1 cannabinoid receptors in the brain and exert intense emotional and cognitive effects. |
2005-01-11 |
2023-08-12 |
Not clear |
| Aldemar Degroot, George G Nomiko. Genetic deletion and pharmacological blockade of CB1 receptors modulates anxiety in the shock-probe burying test. The European journal of neuroscience. vol 20. issue 4. 2004-10-14. PMID:15305874. |
cannabinoids affect various behavioral processes, including emotion, learning and memory, which may be specifically regulated through the cb1 receptors. |
2004-10-14 |
2023-08-12 |
mouse |
| Silvana Gaetani, Vincenzo Cuomo, Daniele Piomell. Anandamide hydrolysis: a new target for anti-anxiety drugs? Trends in molecular medicine. vol 9. issue 11. 2004-08-12. PMID:14604824. |
the major psychoactive constituent of cannabis, delta(9)-tetrahydrocannabinol, affects emotional states in humans and laboratory animals by activating brain cannabinoid receptors. |
2004-08-12 |
2023-08-12 |
rat |
| Marisela Morales, Shwun-De Wang, Oscar Diaz-Ruiz, Diana Hyun-Jin Jh. Cannabinoid CB1 receptor and serotonin 3 receptor subunit A (5-HT3A) are co-expressed in GABA neurons in the rat telencephalon. The Journal of comparative neurology. vol 468. issue 2. 2004-02-10. PMID:14648680. |
cellular coexistence of 5-ht3a and cb1 transcripts in interneurons of the cortex, hippocampal formation, and amygdala suggest possible interactions between the cannabinoid and serotonergic systems at the level of gaba neurotransmission in brain areas involved in cognition, memory, and emotion. |
2004-02-10 |
2023-08-12 |
rat |
| D P Finn, M D Jhaveri, S R G Beckett, C H Roe, D A Kendall, C A Marsden, V Chapma. Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats. Neuropharmacology. vol 45. issue 5. 2003-12-19. PMID:12941373. |
the analgesic potential of cannabinoids may be hampered by their ability to produce aversive emotion when administered systemically. |
2003-12-19 |
2023-08-12 |
rat |
| R J Rodgers, J Haller, J Halasz, E Mikic. 'One-trial sensitization' to the anxiolytic-like effects of cannabinoid receptor antagonist SR141716A in the mouse elevated plus-maze. The European journal of neuroscience. vol 17. issue 6. 2003-06-27. PMID:12670316. |
significant variability in the effects of cannabinoid cb1 receptor ligands on emotional reactivity in animals and humans suggests that the endocannabinoid system may selectively modulate certain types of anxiety. |
2003-06-27 |
2023-08-12 |
mouse |
| Fernando Berrendero, Anna Castañé, Catherine Ledent, Marc Parmentier, Rafael Maldonado, Olga Valverd. Increase of morphine withdrawal in mice lacking A2a receptors and no changes in CB1/A2a double knockout mice. The European journal of neuroscience. vol 17. issue 2. 2003-03-28. PMID:12542668. |
cb1 cannabinoid and a2a adenosine receptors are highly expressed in the central nervous system where they modulate numerous physiological processes including emotional behaviour and the responses of several drugs of abuse. |
2003-03-28 |
2023-08-12 |
mouse |
| Satish Kathuria, Silvana Gaetani, Darren Fegley, Fernando Valiño, Andrea Duranti, Andrea Tontini, Marco Mor, Giorgio Tarzia, Giovanna La Rana, Antonio Calignano, Arcangela Giustino, Maria Tattoli, Maura Palmery, Vincenzo Cuomo, Daniele Piomell. Modulation of anxiety through blockade of anandamide hydrolysis. Nature medicine. vol 9. issue 1. 2003-03-18. PMID:12461523. |
the psychoactive constituent of cannabis, delta(9)-tetrahydrocannabinol, produces in humans subjective responses mediated by cb1 cannabinoid receptors, indicating that endogenous cannabinoids may contribute to the control of emotion. |
2003-03-18 |
2023-08-12 |
rat |
| Miquel Martin, Catherine Ledent, Marc Parmentier, Rafael Maldonado, Olga Valverd. Involvement of CB1 cannabinoid receptors in emotional behaviour. Psychopharmacology. vol 159. issue 4. 2002-04-09. PMID:11823890. |
involvement of cb1 cannabinoid receptors in emotional behaviour. |
2002-04-09 |
2023-08-12 |
mouse |
| Miquel Martin, Catherine Ledent, Marc Parmentier, Rafael Maldonado, Olga Valverd. Involvement of CB1 cannabinoid receptors in emotional behaviour. Psychopharmacology. vol 159. issue 4. 2002-04-09. PMID:11823890. |
endogenous and exogenous cannabinoids acting through the cb1 cannabinoid receptors are implicated in the control of a variety of behavioural and neuroendocrine functions, including emotional responses, and learning and memory processes. |
2002-04-09 |
2023-08-12 |
mouse |