| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucinda M Sisk, Kristina M Rapuano, May I Conley, Abigail S Greene, Corey Horien, Monica D Rosenberg, Dustin Scheinost, R Todd Constable, Charles E Glatt, B J Casey, Dylan G Ge. Genetic variation in endocannabinoid signaling is associated with differential network-level functional connectivity in youth. Journal of neuroscience research. 2021-09-08. PMID:34496065. |
the endocannabinoid system is an important regulator of emotional responses such as fear, and a number of studies have implicated endocannabinoid signaling in anxiety. |
2021-09-08 |
2023-08-13 |
human |
| Sari Goldstein Ferber, Viviana Trezza, Aron Welle. Early life stress and development of the endocannabinoid system: A bidirectional process in programming future coping. Developmental psychobiology. vol 63. issue 2. 2021-08-25. PMID:31849055. |
the endocannabinoid system (ecs) critically regulates stress responsivity and emotional behavior throughout development. |
2021-08-25 |
2023-08-13 |
Not clear |
| Sari Goldstein Ferber, Viviana Trezza, Aron Welle. Early life stress and development of the endocannabinoid system: A bidirectional process in programming future coping. Developmental psychobiology. vol 63. issue 2. 2021-08-25. PMID:31849055. |
manipulations affecting the glucocorticoid and the endocannabinoid systems persistently adjust individual emotional responses and synaptic plasticity. |
2021-08-25 |
2023-08-13 |
Not clear |
| L Sanchez-Marin, A L Gavito, J Decara, A Pastor, E Castilla-Ortega, J Suarez, R de la Torre, F J Pavon, F Rodriguez de Fonseca, A Serran. Impact of intermittent voluntary ethanol consumption during adolescence on the expression of endocannabinoid system and neuroinflammatory mediators. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 33. 2021-08-10. PMID:32057593. |
here, we characterized the gene expression of the endocannabinoid system (ecs) and relevant signaling systems associated with neuroinflammation and emotional behaviors in the brain of young adult control and ethanol-exposed (etoh) rats. |
2021-08-10 |
2023-08-13 |
rat |
| Alexies Dagnino-Subiabr. Stress and Western diets increase vulnerability to neuropsychiatric disorders: A common mechanism. Nutritional neuroscience. vol 24. issue 8. 2021-07-20. PMID:31524571. |
this review suggests that both western diets and negative stress or distress increase n-6/n-3 pufa ratio in the phospholipids of the plasma membrane in neurons, allowing an over-activation of the endocannabinoid system in the limbic areas that control emotions. |
2021-07-20 |
2023-08-13 |
human |
| Shivani Jaiswal, Senthil Raja Ayyanna. Anticancer Potential of Small-Molecule Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase. ChemMedChem. vol 16. issue 14. 2021-07-19. PMID:33834617. |
both faah and magl are the endocannabinoid degrading enzymes that hydrolyze several endogenous ligands, mainly anandamide (aea) and 2-arachidonic glycerol (2-ag), which regulate various pathophysiological conditions in the body such as emotion, cognition, energy balance, pain sensation, neuroinflammation, and cancer cell proliferation. |
2021-07-19 |
2023-08-13 |
Not clear |
| Anna Brancato, Valentina Castelli, Gianluca Lavanco, Rosa Anna Maria Marino, Carla Cannizzar. In utero Δ9-tetrahydrocannabinol exposure confers vulnerability towards cognitive impairments and alcohol drinking in the adolescent offspring: Is there a role for neuropeptide Y? Journal of psychopharmacology (Oxford, England). vol 34. issue 6. 2021-07-08. PMID:32338122. |
indeed, since the endocannabinoid system regulates synaptic plasticity, emotional and cognitive processes from early stages of life interfering with it and other excitability endogenous modulators, such as neuropeptide y (npy), might contribute to the occurrence of a vulnerable phenotype later in life. |
2021-07-08 |
2023-08-13 |
Not clear |
| Jillian L Capodice, Steven A Kapla. The endocannabinoid system, cannabis, and cannabidiol: Implications in urology and men's health. Current urology. vol 15. issue 2. 2021-06-26. PMID:34168527. |
the endocannabinoid system is a neuromodulatory system responsible for partial regulation of cognitive and emotional processes in the human central nervous system such as behavior, mood disorders, and neurologic disorders such as epilepsy. |
2021-06-26 |
2023-08-13 |
human |
| Nathan J Kolla, R Mizrahi, K Karas, C Wang, R M Bagby, S McMain, A I Simpson, P M Rusjan, R Tyndale, S Houle, I Boilea. Elevated fatty acid amide hydrolase in the prefrontal cortex of borderline personality disorder: a [ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 11. 2021-06-23. PMID:32521537. |
fatty acid amide hydrolase (faah), the major catabolic enzyme for the endocannabinoid anandamide, has been proposed as a key regulator of the amygdala-pfc circuit that subserves emotion regulation. |
2021-06-23 |
2023-08-13 |
Not clear |
| Haley A Vecchiarelli, Maria Morena, Catherine M Keenan, Vincent Chiang, Kaitlyn Tan, Min Qiao, Kira Leitl, Alessia Santori, Quentin J Pittman, Keith A Sharkey, Matthew N Hil. Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 5. 2021-06-23. PMID:33452437. |
the endocannabinoid (ecb) system is exquisitely sensitive to these hormonal changes and is a significant regulator of emotional behavior. |
2021-06-23 |
2023-08-13 |
rat |
| Kennia M Silveira, Gregers Wegener, Sâmia R L Joc. Targeting 2-arachidonoylglycerol signalling in the neurobiology and treatment of depression. Basic & clinical pharmacology & toxicology. vol 129. issue 1. 2021-06-10. PMID:33905617. |
through the activation of cannabinoid receptors, 2-ag can interfere with excitatory and inhibitory neurotransmission in different brain regions and modulate behavioural, endocrine and emotional components of the stress response. |
2021-06-10 |
2023-08-13 |
Not clear |
| Ahmad Mobed, Fereshteh Kohansal, Ali Ahmadalipour, Mohammad Hasanzadeh, Flor Zargar. Bioconjugation of 2-arachidonoyl glycerol (2-AG) biotinylated antibody with gold nano-flowers toward immunosensing of 2-AG in human plasma samples: A novel immuno-platform for the screening of immunomodulation and neuroprotection using biosensing. Analytical methods : advancing methods and applications. vol 13. issue 3. 2021-05-14. PMID:33367337. |
human 2-arachidonoylglycerol (2-ag) is an agonist of endocannabinoid system and acts as an important modulator of many physiological processes such as emotional state and pain sensation. |
2021-05-14 |
2023-08-13 |
human |
| Eun-Sang Hwang, Hyun-Bum Kim, Seok Lee, Min-Jeong Kim, Kwan-Joong Kim, Gaeul Han, Se-Young Han, Eun-A Lee, Jeong-Hee Yoon, Dae-Ok Kim, Sungho Maeng, Ji-Ho Par. Antidepressant-like effects of β-caryophyllene on restraint plus stress-induced depression. Behavioural brain research. vol 380. 2021-05-03. PMID:31862467. |
the endocannabinoid system controls cognitive and emotional responses related with stress through the interaction with endocannabinoid receptors. |
2021-05-03 |
2023-08-13 |
Not clear |
| Judit Lazary, Nora Eszlari, Eszter Kriko, Dora Tozser, Peter Dome, J F William Deakin, Gabriella Juhasz, Gyorgy Bagd. Genetic analyses of the endocannabinoid pathway in association with affective phenotypic variants. Neuroscience letters. vol 744. 2021-04-30. PMID:33421489. |
increasing experimental data confirm the crucial role of the endocannabinoid (ecb) system in the regulation of stress response and emotional processes. |
2021-04-30 |
2023-08-13 |
human |
| Luca Steardo, Elvira Anna Carbone, Giulia Menculini, Patrizia Moretti, Luca Steardo, Alfonso Tortorell. Endocannabinoid System as Therapeutic Target of PTSD: A Systematic Review. Life (Basel, Switzerland). vol 11. issue 3. 2021-04-13. PMID:33803374. |
research focused on the endocannabinoid system (ecbs) for anxiety and stress regulation, cognitive and emotional responses modulation and aversive memories extinction, leading to the hypothesis that it could represent a possible alternative treatment target for ptsd. |
2021-04-13 |
2023-08-13 |
Not clear |
| Anna Portugalov, Irit Akira. Do Adolescent Exposure to Cannabinoids and Early Adverse Experience Interact to Increase the Risk of Psychiatric Disorders: Evidence from Rodent Models. International journal of molecular sciences. vol 22. issue 2. 2021-04-12. PMID:33450928. |
we suggest that the effects of cannabinoids on emotional and cognitive function may vary between different sensitive developmental periods. |
2021-04-12 |
2023-08-13 |
Not clear |
| Verity L Chadwick, Cathrin Rohleder, Dagmar Koethe, F Markus Lewek. Cannabinoids and the endocannabinoid system in anxiety, depression, and dysregulation of emotion in humans. Current opinion in psychiatry. vol 33. issue 1. 2021-02-03. PMID:31714262. |
cannabinoids and the endocannabinoid system in anxiety, depression, and dysregulation of emotion in humans. |
2021-02-03 |
2023-08-13 |
Not clear |
| Verity L Chadwick, Cathrin Rohleder, Dagmar Koethe, F Markus Lewek. Cannabinoids and the endocannabinoid system in anxiety, depression, and dysregulation of emotion in humans. Current opinion in psychiatry. vol 33. issue 1. 2021-02-03. PMID:31714262. |
this review is to summarize most recent evidence published in the last 18 months on medical and recreational use of cannabis and cannabinoids in relation to anxiety, depression (unipolar and bipolar), and dysregulation of emotions as part of posttraumatic stress disorders (ptsd) and emotionally instable personality disorders. |
2021-02-03 |
2023-08-13 |
Not clear |
| Roberto Colangeli, Maria Morena, Quentin J Pittman, Matthew N Hill, G Campbell Teske. Anandamide Signaling Augmentation Rescues Amygdala Synaptic Function and Comorbid Emotional Alterations in a Model of Epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 31. 2020-12-31. PMID:32601243. |
epilepsy is often associated with emotional disturbances and the endocannabinoid (ecb) system tunes synaptic transmission in brain regions regulating emotional behavior. |
2020-12-31 |
2023-08-13 |
rat |
| Fengmei Wei, Long Zhao, Yuhong Jin. Signaling molecules targeting cannabinoid receptors: Hemopressin and related peptides. Neuropeptides. vol 79. 2020-11-23. PMID:31831183. |
cannabinoid receptors (cbrs) are part of the endocannabinoid system, which is involved in various physiological processes such as nociception, inflammation, appetite, stress, and emotion regulation. |
2020-11-23 |
2023-08-13 |
Not clear |