| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bin He, Hai-Ying Tao, Shi-Qing Li. Neuroprotective effects of carboxymethylated chitosan on hydrogen peroxide induced apoptosis in Schwann cells. European journal of pharmacology. vol 740. 2015-10-27. PMID:25034812. |
the protective and promotion effects of carboxymethylated chitosan (cmcs) on peripheral nerve and cultured schwann cells (scs) have been demonstrated, but few studies discussed the protective roles of cmcs on scs apoptosis. |
2015-10-27 |
2023-08-13 |
rat |
| Bin He, Hai-Ying Tao, Shi-Qing Li. Neuroprotective effects of carboxymethylated chitosan on hydrogen peroxide induced apoptosis in Schwann cells. European journal of pharmacology. vol 740. 2015-10-27. PMID:25034812. |
rat scs were isolated and cultured in vitro, hydrogen peroxide (h2o2) was used to establish the apoptosis models of scs. |
2015-10-27 |
2023-08-13 |
rat |
| Bin He, Hai-Ying Tao, Shi-Qing Li. Neuroprotective effects of carboxymethylated chitosan on hydrogen peroxide induced apoptosis in Schwann cells. European journal of pharmacology. vol 740. 2015-10-27. PMID:25034812. |
the apoptosis of scs was detected by flow cytometry (fcm) analysis. |
2015-10-27 |
2023-08-13 |
rat |
| Bin He, Hai-Ying Tao, Shi-Qing Li. Neuroprotective effects of carboxymethylated chitosan on hydrogen peroxide induced apoptosis in Schwann cells. European journal of pharmacology. vol 740. 2015-10-27. PMID:25034812. |
fcm assay and hoechst33342 staining results indicated that cmcs could protect scs from apoptosis with dose and time-dependent manner. |
2015-10-27 |
2023-08-13 |
rat |
| Bin He, Hai-Ying Tao, Shi-Qing Li. Neuroprotective effects of carboxymethylated chitosan on hydrogen peroxide induced apoptosis in Schwann cells. European journal of pharmacology. vol 740. 2015-10-27. PMID:25034812. |
the present study indicates cmcs has the neuroprotective effect on peripheral nerves and inhibit scs apoptosis. |
2015-10-27 |
2023-08-13 |
rat |
| Bin He, Haiying Tao, Shiqing Li. [Effect of carboxymethylated chitosan on apoptosis and expression of brain derived neurotrophic factor and glial cell line derived neurotrophic factor in oxidative stress induced Schwann cells in vitro]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 28. issue 12. 2015-07-17. PMID:25826901. |
to investigate the protective effects of carboxymethylated chitosan (cmcs) on oxidative stress induced apoptosis of schwann cells (scs), and the expressions of brain derived neurotrophic factor (bdnf) and glial cell line derived neurotrophic factor (gdnf) in oxidative stress induced scs. |
2015-07-17 |
2023-08-13 |
Not clear |
| Bin He, Haiying Tao, Ailin Wei, Shiqing Liu, Haohuan L. [Effects of pyrroloquinoline quinine on oxidative stress-induced apoptosis of Schwann cells and its mechanism]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 30. issue 2. 2015-05-16. PMID:24941762. |
to investigate the effects of pyrroloquinoline quinine (pqq) on hydrogen peroxide-induced apoptosis of schwann cells (scs) and its mechanism. |
2015-05-16 |
2023-08-13 |
Not clear |
| Xiu-Min Lu, Ya-Hai Shu, Chun-Hong Qiu, Kai-Ting Chen, Yong-Tang Wan. Protective effects and anti-apoptotic role of nerve growth factor on spinal cord neurons in sciatic nerve-injured rats. Neurological research. vol 36. issue 9. 2015-03-30. PMID:24620979. |
the purpose of this study is to demonstrate a dependence of spinal cord motoneurons on the communication with their targets, sciatic nerves, and investigate whether the effects of nerve growth factor (ngf) on the spinal cord neuron apoptosis and surviving through the regulation of nuclear factor-kappa b (nf-kappab) in schwann cells (scs) in sciatic nerve injured rats. |
2015-03-30 |
2023-08-12 |
rat |
| Ting Yu, Lei Li, Yanwen Bi, Zhen Liu, Huaxiang Liu, Zhenzhong L. Erythropoietin attenuates oxidative stress and apoptosis in Schwann cells isolated from streptozotocin-induced diabetic rats. The Journal of pharmacy and pharmacology. vol 66. issue 8. 2015-03-30. PMID:24673486. |
high glucose-evoked oxidative stress and apoptosis within schwann cells (scs) are mechanisms facilitating the procession of diabetic peripheral neuropathy (dpn). |
2015-03-30 |
2023-08-12 |
rat |
| Ting Yu, Lei Li, Yanwen Bi, Zhen Liu, Huaxiang Liu, Zhenzhong L. Erythropoietin attenuates oxidative stress and apoptosis in Schwann cells isolated from streptozotocin-induced diabetic rats. The Journal of pharmacy and pharmacology. vol 66. issue 8. 2015-03-30. PMID:24673486. |
although erythropoietin (epo) was demonstrated to have neuroprotective effects in neurodegenerative diseases, the effects of epo on glucose-evoked oxidative stress and apoptosis of scs remain unknown. |
2015-03-30 |
2023-08-12 |
rat |
| Maarja Laos, Tommi Anttonen, Anna Kirjavainen, Taija af Hällström, Marikki Laiho, Ulla Pirvol. DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells. Aging. vol 6. issue 6. 2015-02-23. PMID:25063730. |
compared to juvenile scs, γh2ax and the repair protein rad51 were resolved with slower kinetics in adult scs, accompanied by increased apoptosis. |
2015-02-23 |
2023-08-13 |
mouse |
| Guomin Liu, Xukai Wang, Guoxi Shao, Qinyi Li. Genetically modified Schwann cells producing glial cell line-derived neurotrophic factor inhibit neuronal apoptosis in rat spinal cord injury. Molecular medicine reports. vol 9. issue 4. 2014-10-21. PMID:24549701. |
the engineered scs were characterized by their ability to express and secrete biologically active gdnf, which was shown to inhibit apoptosis of primary rat neurons induced by radiation, and upregulate the expression of b‑cell lymphoma 2 (bcl‑2) and downregulate the expression of bcl‑2 associated x protein (bax) in vitro. |
2014-10-21 |
2023-08-12 |
rat |
| Guomin Liu, Xukai Wang, Guoxi Shao, Qinyi Li. Genetically modified Schwann cells producing glial cell line-derived neurotrophic factor inhibit neuronal apoptosis in rat spinal cord injury. Molecular medicine reports. vol 9. issue 4. 2014-10-21. PMID:24549701. |
transplantation of unmodified and genetically modified scs producing gdnf attenuated sci by inhibiting apoptosis via the bcl‑2/bax pathways. |
2014-10-21 |
2023-08-12 |
rat |
| Norio Yamamoto, Takayuki Nakagawa, Juichi It. Application of insulin-like growth factor-1 in the treatment of inner ear disorders. Frontiers in pharmacology. vol 5. 2014-10-13. PMID:25309440. |
in the aminoglycoside-treated neonatal mouse cochlear explant culture, promotion of the cell-cycle in scs as well as inhibition of hc apoptosis was observed in the igf-1-treated group. |
2014-10-13 |
2023-08-13 |
mouse |
| Haipeng Zhu, Peter Pytel, Christopher M Gome. Selective inhibition of caspases in skeletal muscle reverses the apoptotic synaptic degeneration in slow-channel myasthenic syndrome. Human molecular genetics. vol 23. issue 1. 2014-08-04. PMID:23943790. |
together with previous studies, these results indicate that focal activation of caspase activity at the nmj is the principal pathological process responsible for the synaptic apoptosis in scs. |
2014-08-04 |
2023-08-12 |
mouse |
| Ting Gui, Yueming Wang, Lixing Zhang, Wenjing Wang, Hao Zhu, Wenlong Din. Krüppel-like factor 6 rendered rat Schwann cell more sensitive to apoptosis via upregulating FAS expression. PloS one. vol 8. issue 12. 2014-07-31. PMID:24324791. |
the apoptosis inducers tnfα and cisplatin upregulated klf6 expression in primary cultured scs and the sc line rsc96. |
2014-07-31 |
2023-08-12 |
rat |
| Ting Gui, Yueming Wang, Lixing Zhang, Wenjing Wang, Hao Zhu, Wenlong Din. Krüppel-like factor 6 rendered rat Schwann cell more sensitive to apoptosis via upregulating FAS expression. PloS one. vol 8. issue 12. 2014-07-31. PMID:24324791. |
these data suggest that klf6 upregulation may render scs more vulnerable to apoptosis after injury via upregulating fas expression. |
2014-07-31 |
2023-08-12 |
rat |
| Lian Li, Cheng-Min Li, Jie Wu, Shuai Huang, Gen-Lin Wan. Heat shock protein 32/heme oxygenase-1 protects mouse Sertoli cells from hyperthermia-induced apoptosis by CO activation of sGC signalling pathways. Cell biology international. vol 38. issue 1. 2014-07-24. PMID:24038883. |
we hypothesise that hsp32/ho-1 and co generated from it provide survival advantages in scs by preventing apoptosis under heat exposure. |
2014-07-24 |
2023-08-12 |
mouse |
| Lian Li, Cheng-Min Li, Jie Wu, Shuai Huang, Gen-Lin Wan. Heat shock protein 32/heme oxygenase-1 protects mouse Sertoli cells from hyperthermia-induced apoptosis by CO activation of sGC signalling pathways. Cell biology international. vol 38. issue 1. 2014-07-24. PMID:24038883. |
after treatment of cultured scs with hyperthermia and/or hsp32/ho-1 activater hemin, apoptosis was measured valuated by annexin v-fitc and caspase-3 activation. |
2014-07-24 |
2023-08-12 |
mouse |
| Lian Li, Cheng-Min Li, Jie Wu, Shuai Huang, Gen-Lin Wan. Heat shock protein 32/heme oxygenase-1 protects mouse Sertoli cells from hyperthermia-induced apoptosis by CO activation of sGC signalling pathways. Cell biology international. vol 38. issue 1. 2014-07-24. PMID:24038883. |
hyperthermia induced scs apoptosis, while preincubation with hemin suppressed sc hyperthermia-induced apoptosis. |
2014-07-24 |
2023-08-12 |
mouse |