| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bhupinder P S Vohra, Jason S Groshong, Roberto Zayas, Robert L Wollmann, Christopher M Gome. Activation of apoptotic pathways at muscle fiber synapses is circumscribed and reversible in a slow-channel syndrome model. Neurobiology of disease. vol 23. issue 2. 2006-11-27. PMID:16815027. |
identification of extrasynaptic factors that prevent the spread of apoptosis in scs muscle fibers may aid in developing treatments for neurological disorders characterized by excitotoxicity or apoptosis. |
2006-11-27 |
2023-08-12 |
mouse |
| Christopher R Hayworth, Susan E Moody, Lewis A Chodosh, Paul Krieg, Mendell Rimer, Wesley J Thompso. Induction of neuregulin signaling in mouse schwann cells in vivo mimics responses to denervation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 25. 2006-07-11. PMID:16793894. |
last, induction of the active receptor is sufficient to rescue scs in neonatal muscle from denervation-induced apoptosis. |
2006-07-11 |
2023-08-12 |
mouse |
| Rosane B Oliveira, Elizabeth P Sampaio, Fernando Aarestrup, Rosane M B Teles, Tatiana P Silva, Ariane L Oliveira, Paulo R Z Antas, Euzenir N Sarn. Cytokines and Mycobacterium leprae induce apoptosis in human Schwann cells. Journal of neuropathology and experimental neurology. vol 64. issue 10. 2005-11-03. PMID:16215460. |
it is possible that cytokine production and apoptosis of schwann cells (scs) directly affect nerve degeneration and regeneration leading to injury of the myelin sheath and axon. |
2005-11-03 |
2023-08-12 |
human |
| Michiru Fukunaga, Satoshi Miyata, Satomi Higo, Yasuhiro Hamada, Shigemitsu Ueyama, Masato Kasug. Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells. Annals of the New York Academy of Sciences. vol 1043. 2005-10-27. PMID:16037234. |
we found that mg was capable of inducing apoptosis in peripheral nerve-derived schwann cells (scs) in a time- and dose-dependent manner, accompanied by a reduction of intracellular glutathione content. |
2005-10-27 |
2023-08-12 |
rat |
| Michiru Fukunaga, Satoshi Miyata, Bing Fen Liu, Hiroyuki Miyazaki, Yushi Hirota, Satomi Higo, Yasuhiro Hamada, Shigemitsu Ueyama, Masato Kasug. Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells. Biochemical and biophysical research communications. vol 320. issue 3. 2004-08-26. PMID:15240103. |
we examined whether mg was capable of inducing apoptosis in schwann cells (scs), since recent studies have suggested a potential involvement of apoptotic cell death in the development of diabetic neuropathy. |
2004-08-26 |
2023-08-12 |
rat |
| Michiru Fukunaga, Satoshi Miyata, Bing Fen Liu, Hiroyuki Miyazaki, Yushi Hirota, Satomi Higo, Yasuhiro Hamada, Shigemitsu Ueyama, Masato Kasug. Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells. Biochemical and biophysical research communications. vol 320. issue 3. 2004-08-26. PMID:15240103. |
mg induced apoptosis in scs in a dose-dependent manner, accompanied by a reduction of intracellular glutathione content and activation of the p38 mapk. |
2004-08-26 |
2023-08-12 |
rat |
| Michiru Fukunaga, Satoshi Miyata, Bing Fen Liu, Hiroyuki Miyazaki, Yushi Hirota, Satomi Higo, Yasuhiro Hamada, Shigemitsu Ueyama, Masato Kasug. Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells. Biochemical and biophysical research communications. vol 320. issue 3. 2004-08-26. PMID:15240103. |
inhibiting the p38 mapk activation by sb203580 successfully suppressed the mg-induced apoptosis in scs. |
2004-08-26 |
2023-08-12 |
rat |
| Bhupinder P S Vohra, Jason S Groshong, Ricardo A Maselli, M Anthony Verity, Robert L Wollmann, Christopher M Gome. Focal caspase activation underlies the endplate myopathy in slow-channel syndrome. Annals of neurology. vol 55. issue 3. 2004-04-12. PMID:14991812. |
using antisera specific for the activated forms of caspases, the family of cysteine proteases that underlies apoptosis, we demonstrated that active forms of initiator and effector caspases are selectively localized at the nmj in scs. |
2004-04-12 |
2023-08-12 |
human |
| Marina Prisco, Annamaria Liguoro, Raffaella Comitato, Anna Cardone, Barbara D'Onghia, Loredana Ricchiari, Francesco Angelini, Piero Andreuccett. Apoptosis during spermatogenesis in the spotted ray Torpedo marmorata. Molecular reproduction and development. vol 64. issue 3. 2003-07-18. PMID:12548666. |
apoptosis also takes place in mature cysts after sperm release to eliminate most of the scs. |
2003-07-18 |
2023-08-12 |
Not clear |
| Malika Yousfi, Francoise Lasmoles, Vincent El Ghouzzi, Pierre J Mari. Twist haploinsufficiency in Saethre-Chotzen syndrome induces calvarial osteoblast apoptosis due to increased TNFalpha expression and caspase-2 activation. Human molecular genetics. vol 11. issue 4. 2002-07-09. PMID:11854168. |
here we show that twist haploinsufficiency alters osteoblast apoptosis in scs. |
2002-07-09 |
2023-08-12 |
human |
| Malika Yousfi, Francoise Lasmoles, Vincent El Ghouzzi, Pierre J Mari. Twist haploinsufficiency in Saethre-Chotzen syndrome induces calvarial osteoblast apoptosis due to increased TNFalpha expression and caspase-2 activation. Human molecular genetics. vol 11. issue 4. 2002-07-09. PMID:11854168. |
analysis of terminal deoxynucleotidyl transferase-mediated nick-end labelling (tunel) demonstrated increased osteoblast and osteocyte apoptosis in coronal sutures from two scs patients with nonsense mutations (y103x and q109x) that result in the synthesis of bhlh-truncated proteins, and one patient with a missense mutation in the basic domain (r118c) that abolishes twist dna binding. |
2002-07-09 |
2023-08-12 |
human |
| Malika Yousfi, Francoise Lasmoles, Vincent El Ghouzzi, Pierre J Mari. Twist haploinsufficiency in Saethre-Chotzen syndrome induces calvarial osteoblast apoptosis due to increased TNFalpha expression and caspase-2 activation. Human molecular genetics. vol 11. issue 4. 2002-07-09. PMID:11854168. |
these studies provide novel evidence that twist haploinsufficiency in scs promotes osteoblast apoptosis by a tnfalpha-caspase-2-caspase-8-caspases-3, -6, -7 cascade, and uncover a molecular mechanism in which twist plays an anti-apoptotic role in human calvarial osteoblasts. |
2002-07-09 |
2023-08-12 |
human |
| C L Delaney, J W Russell, H L Cheng, E L Feldma. Insulin-like growth factor-I and over-expression of Bcl-xL prevent glucose-mediated apoptosis in Schwann cells. Journal of neuropathology and experimental neurology. vol 60. issue 2. 2001-03-29. PMID:11273003. |
electron microscopy of dorsal root ganglia from stz-treated rats reveals classic ultrastructural features of apoptosis in scs, including chromatin clumping and prominent vacuolation. |
2001-03-29 |
2023-08-12 |
rat |
| C L Delaney, J W Russell, H L Cheng, E L Feldma. Insulin-like growth factor-I and over-expression of Bcl-xL prevent glucose-mediated apoptosis in Schwann cells. Journal of neuropathology and experimental neurology. vol 60. issue 2. 2001-03-29. PMID:11273003. |
although bcl-xl expression remains unchanged in experimental conditions, over-expression of bcl-xl protects scs from apoptosis. |
2001-03-29 |
2023-08-12 |
rat |
| C L Delaney, J W Russell, H L Cheng, E L Feldma. Insulin-like growth factor-I and over-expression of Bcl-xL prevent glucose-mediated apoptosis in Schwann cells. Journal of neuropathology and experimental neurology. vol 60. issue 2. 2001-03-29. PMID:11273003. |
over-expression of bcl-xl, or igf-i, signaling via pi 3-kinase, protects scs from glucose-mediated apoptosis in vitro. |
2001-03-29 |
2023-08-12 |
rat |
| M T Berciano, R Fernandez, E Pena, E Calle, N T Villagra, M Lafarg. Necrosis of schwann cells during tellurium-induced primary demyelination: DNA fragmentation, reorganization of splicing machinery, and formation of intranuclear rods of actin. Journal of neuropathology and experimental neurology. vol 58. issue 12. 1999-12-29. PMID:10604748. |
unlike the apoptosis of pre-remyelinating scs (11), this caspase independent cell death of necrotic type involves mature pre-demyelinating scs and eliminates scs injured by the neurotoxic effect of te. |
1999-12-29 |
2023-08-12 |
rat |
| K Sasaki, H Ino, T Chiba, E Adachi-Usam. Light-induced apoptosis in the neonatal mouse retina and superior colliculus. Investigative ophthalmology & visual science. vol 40. issue 13. 1999-12-09. PMID:10586927. |
light-induced apoptosis in the neonatal mouse retina and superior colliculus. |
1999-12-09 |
2023-08-12 |
mouse |
| K Sasaki, H Ino, T Chiba, E Adachi-Usam. Light-induced apoptosis in the neonatal mouse retina and superior colliculus. Investigative ophthalmology & visual science. vol 40. issue 13. 1999-12-09. PMID:10586927. |
apoptosis occurs naturally in the rodent retina and superior colliculus (sc) during the neonatal period. |
1999-12-09 |
2023-08-12 |
mouse |
| M T Berciano, E Calle, R Fernández, M Lafarg. Regulation of Schwann cell numbers in tellurium-induced neuropathy: apoptosis, supernumerary cells and internodal shortening. Acta neuropathologica. vol 95. issue 3. 1998-05-22. PMID:9542592. |
dying cells exhibited morphological features of apoptosis and appeared enclosed by lamellar processes of adjacent healthy scs in extracellular compartments. |
1998-05-22 |
2023-08-12 |
rat |
| M T Berciano, E Calle, R Fernández, M Lafarg. Regulation of Schwann cell numbers in tellurium-induced neuropathy: apoptosis, supernumerary cells and internodal shortening. Acta neuropathologica. vol 95. issue 3. 1998-05-22. PMID:9542592. |
these results indicate that a portion of redundant immature scs are susceptible to elimination by apoptosis. |
1998-05-22 |
2023-08-12 |
rat |