Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Qin Yuan, Huiguang Yang, Chun Cheng, Chunmiao Li, Xiujie Wu, Weipeng Huan, Huiqing Sun, Zhengming Zhou, Yingying Wang, Yunhong Zhao, Xiang Lu, Aiguo She. β-1,4-Galactosyltransferase I involved in Schwann cells proliferation and apoptosis induced by tumor necrosis factor-alpha via the activation of MAP kinases signal pathways. Molecular and cellular biochemistry. vol 365. issue 1-2. 2012-08-20. PMID:22359038. |
we also found anti-tnfr2 antibody suppressed low concentration of tnf-α-induced scs proliferation, while anti-tnfr1 antibody inhibited high concentration of tnf-α-induced scs apoptosis. |
2012-08-20 |
2023-08-12 |
Not clear |
Qin Yuan, Huiguang Yang, Chun Cheng, Chunmiao Li, Xiujie Wu, Weipeng Huan, Huiqing Sun, Zhengming Zhou, Yingying Wang, Yunhong Zhao, Xiang Lu, Aiguo She. β-1,4-Galactosyltransferase I involved in Schwann cells proliferation and apoptosis induced by tumor necrosis factor-alpha via the activation of MAP kinases signal pathways. Molecular and cellular biochemistry. vol 365. issue 1-2. 2012-08-20. PMID:22359038. |
thus, present data show that β-1,4-galt i may play an important role in scs proliferation and apoptosis induced by tnf-α via different signal pathways and tnfr. |
2012-08-20 |
2023-08-12 |
Not clear |
Xinjing Luo, Lingjian Tao, Peng Lin, Xuanrong Mo, Haixiao Che. Extracellular heat shock protein 72 protects schwann cells from hydrogen peroxide-induced apoptosis. Journal of neuroscience research. vol 90. issue 6. 2012-08-10. PMID:22488728. |
we determined that extracellular exposure to hsp72 reduced cell death in rat scs in a dose-dependent manner, with the protection resulting from downregulation of apoptosis induced by h₂o₂ (as shown by tunel and annexin v flow cytometry analyses). |
2012-08-10 |
2023-08-12 |
rat |
Ronit Elhasid, Sarit Larisc. ARTS-based anticancer therapy: taking aim at cancer stem cells. Future oncology (London, England). vol 7. issue 10. 2012-02-07. PMID:21992730. |
in particular, septin 4/arts-deficient mice have increased tumor susceptibility and contain increased numbers of stem cells (scs) and progenitor cells, apparently owing to their resistance towards apoptosis. |
2012-02-07 |
2023-08-12 |
mouse |
Ronit Elhasid, Sarit Larisc. ARTS-based anticancer therapy: taking aim at cancer stem cells. Future oncology (London, England). vol 7. issue 10. 2012-02-07. PMID:21992730. |
first, loss of arts-mediated apoptosis leads to increased numbers of normal scs. |
2012-02-07 |
2023-08-12 |
mouse |
Ronit Elhasid, Sarit Larisc. ARTS-based anticancer therapy: taking aim at cancer stem cells. Future oncology (London, England). vol 7. issue 10. 2012-02-07. PMID:21992730. |
second, after these scs acquire additional transforming mutations and become cancer sc (cscs), they are more likely to survive in the absence of arts owing to increased resistance toward apoptosis. |
2012-02-07 |
2023-08-12 |
mouse |
Elisabetta Mantuano, Kenneth Henry, Tomonori Yamauchi, Nobuhiko Hiramatsu, Kazuyo Yamauchi, Sumihisa Orita, Kazuhisa Takahashi, Jonathan H Lin, Steven L Gonias, W Marie Campan. The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 38. 2011-12-07. PMID:21940431. |
lrp1 functions as a potent activator of pi3k in scs and, by this mechanism, limits sc apoptosis resulting from increased chop expression in nerve injury. |
2011-12-07 |
2023-08-12 |
rat |
Caitlin E Hill, Yelena Guller, Scott J Raffa, Andres Hurtado, Mary Bartlett Bung. A calpain inhibitor enhances the survival of Schwann cells in vitro and after transplantation into the injured spinal cord. Journal of neurotrauma. vol 27. issue 9. 2011-08-08. PMID:20568964. |
recently we demonstrated rapid and early death of schwann cells (scs) within the first 24 h after transplantation, by both necrosis and apoptosis, which results in fewer than 20% of the cells surviving beyond 1 week. |
2011-08-08 |
2023-08-12 |
Not clear |
Ashleigh E Nugent, Denise L McBurney, Walter E Horto. The presence of extracellular matrix alters the chondrocyte response to endoplasmic reticulum stress. Journal of cellular biochemistry. vol 112. issue 4. 2011-08-01. PMID:21308740. |
scs treated with er stressors did not up-regulate gadd153, suggesting that the cells experienced er stress but would not undergo apoptosis. |
2011-08-01 |
2023-08-12 |
cattle |
Ashleigh E Nugent, Denise L McBurney, Walter E Horto. The presence of extracellular matrix alters the chondrocyte response to endoplasmic reticulum stress. Journal of cellular biochemistry. vol 112. issue 4. 2011-08-01. PMID:21308740. |
in fact, scs undergo apoptosis upon er stress treatment after 0-1 day of growth; however, after 4 days and to 6 weeks, apoptosis in treated samples was not different than controls. |
2011-08-01 |
2023-08-12 |
cattle |
Li Lei, Demin Han, Shusheng Gong, Jun Zheng, Jin X. Mpz gene suppression by shRNA increases Schwann cell apoptosis in vitro. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 31. issue 5. 2011-01-07. PMID:20552241. |
flow cytometric analysis and terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) were used to determine the cell cycle and the amount of apoptosis of scs. |
2011-01-07 |
2023-08-12 |
Not clear |
Xinjing Luo, Baoguo Chen, Rui Zheng, Peng Lin, Jicheng Li, Haixiao Che. Hydrogen peroxide induces apoptosis through the mitochondrial pathway in rat Schwann cells. Neuroscience letters. vol 485. issue 1. 2011-01-04. PMID:20813162. |
it has been shown that hydrogen peroxide (h(2)o(2)) induces apoptosis in several kinds of cells; however, the role of h(2)o(2) in the apoptosis of schwann cells (scs) is currently unclear. |
2011-01-04 |
2023-08-12 |
rat |
Xinjing Luo, Baoguo Chen, Rui Zheng, Peng Lin, Jicheng Li, Haixiao Che. Hydrogen peroxide induces apoptosis through the mitochondrial pathway in rat Schwann cells. Neuroscience letters. vol 485. issue 1. 2011-01-04. PMID:20813162. |
the objective of this study was to determine whether h(2)o(2) is capable of inducing apoptosis in scs and whether or not such an effect is associated with the activation of mitochondrial pathway. |
2011-01-04 |
2023-08-12 |
rat |
Xinjing Luo, Baoguo Chen, Rui Zheng, Peng Lin, Jicheng Li, Haixiao Che. Hydrogen peroxide induces apoptosis through the mitochondrial pathway in rat Schwann cells. Neuroscience letters. vol 485. issue 1. 2011-01-04. PMID:20813162. |
we demonstrated that h(2)o(2) induces apoptosis in scs, and is associated with increased release of cytochrome c from mitochondria and the activation of caspase-3 and -9 by up-regulation of bax and down-regulation of bcl-2. |
2011-01-04 |
2023-08-12 |
rat |
Yiorgos Apidianakis, Chrysoula Pitsouli, Norbert Perrimon, Laurence Rahm. Synergy between bacterial infection and genetic predisposition in intestinal dysplasia. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 49. 2010-09-08. PMID:19934041. |
this, in turn, causes apoptosis of enterocytes, the largest class of differentiated intestinal cells, and promotes a dramatic proliferation of scs and progenitors that serves as a homeostatic compensatory mechanism to replenish the apoptotic enterocytes. |
2010-09-08 |
2023-08-12 |
human |
Yongwei Qin, Chun Cheng, Haibo Wang, Xiaoyi Shao, Yongjing Gao, Aiguo She. TNF-alpha as an autocrine mediator and its role in the activation of Schwann cells. Neurochemical research. vol 33. issue 6. 2008-07-24. PMID:18205044. |
furthermore, tnf-alpha is involved in the induction of apoptosis through binding to tnfr in scs. |
2008-07-24 |
2023-08-12 |
Not clear |
Matthew J Provenzano, Ningyong Xu, Mark R Ver Meer, J Jason Clark, Marlan R Hanse. p75NTR and sortilin increase after facial nerve injury. The Laryngoscope. vol 118. issue 1. 2008-02-25. PMID:18090258. |
after axotomy, schwann cells (scs), required for successful nerve regeneration, undergo a number of cellular changes including dedifferentiation, proliferation, expression of molecules that support axon growth, and apoptosis. |
2008-02-25 |
2023-08-12 |
Not clear |
Biju Parekkadan, Daan van Poll, Zaki Megeed, Naoya Kobayashi, Arno W Tilles, François Berthiaume, Martin L Yarmus. Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells. Biochemical and biophysical research communications. vol 363. issue 2. 2007-11-26. PMID:17869217. |
indirect coculture of mscs and activated scs led to a significant decrease in collagen deposition and proliferation, while inducing apoptosis of activated scs. |
2007-11-26 |
2023-08-12 |
Not clear |
Biju Parekkadan, Daan van Poll, Zaki Megeed, Naoya Kobayashi, Arno W Tilles, François Berthiaume, Martin L Yarmus. Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells. Biochemical and biophysical research communications. vol 363. issue 2. 2007-11-26. PMID:17869217. |
in addition, release of hgf by mscs was responsible for the marked induction of apoptosis in scs as determined by antibody-neutralization studies. |
2007-11-26 |
2023-08-12 |
Not clear |
Caitlin E Hill, Andres Hurtado, Bas Blits, Ben A Bahr, Patrick M Wood, Mary Bartlett Bunge, Martin Oudeg. Early necrosis and apoptosis of Schwann cells transplanted into the injured rat spinal cord. The European journal of neuroscience. vol 26. issue 6. 2007-11-20. PMID:17880386. |
to assess the extent and temporal profile of transplanted cell death, and the contributions of necrosis and apoptosis to this cell death following spinal cord injury, different concentrations of schwann cells (scs), lentivirally transduced to express green fluorescent protein (gfp), were transplanted into a 1-week-old moderate contusion of the adult rat thoracic spinal cord. |
2007-11-20 |
2023-08-12 |
rat |