| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Frisc. Reversal of malignancy by the adenovirus E1a gene. Mutation research. vol 350. issue 1. 1996-07-26. PMID:8657190. |
furthermore, epithelial cells are sensitive to a form of apoptosis - 'anoikis' - that is induced by detachment from extracellular matrix. |
1996-07-26 |
2023-08-12 |
Not clear |
| C S Williams, R N DuBoi. Prostaglandin endoperoxide synthase: why two isoforms? The American journal of physiology. vol 270. issue 3 Pt 1. 1996-07-05. PMID:8638704. |
overexpression of cox-2 in intestinal epithelial cells results in increased adhesion to extracellular matrix proteins and inhibition of apoptosis. |
1996-07-05 |
2023-08-12 |
mouse |
| H M Beere, C M Chresta, J A Hickma. Selective inhibition of topoisomerase II by ICRF-193 does not support a role for topoisomerase II activity in the fragmentation of chromatin during apoptosis of human leukemia cells. Molecular pharmacology. vol 49. issue 5. 1996-06-19. PMID:8622634. |
topoisomerase ii plays a role in the attachment of 50-kilobase domains of dna to the nuclear matrix; fragments of this size are cleaved during apoptosis. |
1996-06-19 |
2023-08-12 |
human |
| N Boudreau, Z Werb, M J Bissel. Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 8. 1996-06-18. PMID:8622967. |
the basement membrane (bm) extracellular matrix induces differentiation and suppresses apoptosis in mammary epithelial cells, whereas cells lacking bm lose their differentiated phenotype and undergo apoptosis. |
1996-06-18 |
2023-08-12 |
Not clear |
| S Hara, H D Halicka, S Bruno, J Gong, F Traganos, Z Darzynkiewic. Effect of protease inhibitors on early events of apoptosis. Experimental cell research. vol 223. issue 2. 1996-05-03. PMID:8601414. |
because nuclear matrix proteins and histones stabilize dna in situ, and the decrease in dna stability which occurs during apoptosis is precluded by the inhibitors, it is likely that serine proteases may degrade dna stabilizing proteins. |
1996-05-03 |
2023-08-12 |
human |
| C J Narvaez, K Vanweelden, I Byrne, J Wels. Characterization of a vitamin D3-resistant MCF-7 cell line. Endocrinology. vol 137. issue 2. 1996-04-09. PMID:8593782. |
we have previously demonstrated that 1,25-(oh)2d3 induces morphology (pyknotic nuclei, chromatin and cytoplasmic condensation, and nuclear matrix protein reorganization) consistent with the activation of apoptosis in mcf-7 cells. |
1996-04-09 |
2023-08-12 |
Not clear |
| L R Lund, J Rømer, N Thomasset, H Solberg, C Pyke, M J Bissell, K Danø, Z Wer. Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. Development (Cambridge, England). vol 122. issue 1. 1996-03-07. PMID:8565829. |
our data support the hypothesis that there are at least two distinct phases of involution: an initial phase, characterized by induction of the apoptosis-associated genes sgp-2 and ice and apoptosis of fully differentiated mammary epithelial cells without visible degradation of the extracellular matrix, and a second phase, characterized by extracellular matrix remodeling and altered mesenchymal-epithelial interactions, followed by apoptosis of cells that are losing differentiated functions. |
1996-03-07 |
2023-08-12 |
mouse |
| M M Tinnemans, M H Lenders, G P ten Velde, F C Ramaekers, B Schutt. Alterations in cytoskeletal and nuclear matrix-associated proteins during apoptosis. European journal of cell biology. vol 68. issue 1. 1996-02-22. PMID:8549588. |
it appeared that nuclear matrix components remained detectable in cells undergoing spontaneous apoptosis. |
1996-02-22 |
2023-08-12 |
Not clear |
| M M Tinnemans, M H Lenders, G P ten Velde, F C Ramaekers, B Schutt. Alterations in cytoskeletal and nuclear matrix-associated proteins during apoptosis. European journal of cell biology. vol 68. issue 1. 1996-02-22. PMID:8549588. |
the persistence of nuclear matrix components is therefore a useful marker for the detection of apoptosis. |
1996-02-22 |
2023-08-12 |
Not clear |
| R C Bates, L F Lincz, G F Burn. Involvement of integrins in cell survival. Cancer metastasis reviews. vol 14. issue 3. 1996-02-20. PMID:8548868. |
the extracellular matrix (ecm) is known to play a regulatory role in cellular growth and differentiation, but only more recently has it been recognized as a regulator of apoptosis. |
1996-02-20 |
2023-08-12 |
Not clear |
| G J Gibson, W J Kohler, M B Schaffle. Chondrocyte apoptosis in endochondral ossification of chick sterna. Developmental dynamics : an official publication of the American Association of Anatomists. vol 203. issue 4. 1996-01-17. PMID:7496038. |
light microscopy of resorbing sterna demonstrated chondrocyte condensation at the interface with the invading vasculature and electron microscopy demonstrated a range of chondrocyte morphologies, including retraction from the pericellular matrix, cytoplasmic and nuclear condensation, and vesiculation suggestive of sequential changes characteristic of apoptosis. |
1996-01-17 |
2023-08-12 |
chicken |
| M Zweyer, R Bareggi, V Grill, M R Soranzo, R A Marugg, B M Riederer, P Narducci, A M Martell. Behavior of nuclear matrix proteins during camptothecin-induced apoptosis in HL-60 human leukemia cells. Experimental cell research. vol 221. issue 1. 1995-12-14. PMID:7589253. |
behavior of nuclear matrix proteins during camptothecin-induced apoptosis in hl-60 human leukemia cells. |
1995-12-14 |
2023-08-12 |
human |
| M Zweyer, R Bareggi, V Grill, M R Soranzo, R A Marugg, B M Riederer, P Narducci, A M Martell. Behavior of nuclear matrix proteins during camptothecin-induced apoptosis in HL-60 human leukemia cells. Experimental cell research. vol 221. issue 1. 1995-12-14. PMID:7589253. |
in this study we focused our attention on the behavior of four nuclear matrix proteins during the various stages of apoptosis in the hl-60 cell line exposed to the dna topoisomerase i inhibitor, camptothecin. |
1995-12-14 |
2023-08-12 |
human |
| M Zweyer, R Bareggi, V Grill, M R Soranzo, R A Marugg, B M Riederer, P Narducci, A M Martell. Behavior of nuclear matrix proteins during camptothecin-induced apoptosis in HL-60 human leukemia cells. Experimental cell research. vol 221. issue 1. 1995-12-14. PMID:7589253. |
indirect immunofluorescence experiments were performed to follow these nuclear matrix antigens during apoptosis. |
1995-12-14 |
2023-08-12 |
human |
| H A Gelbard, H J James, L R Sharer, S W Perry, Y Saito, A M Kazee, B M Blumberg, L G Epstei. Apoptotic neurons in brains from paediatric patients with HIV-1 encephalitis and progressive encephalopathy. Neuropathology and applied neurobiology. vol 21. issue 3. 1995-11-27. PMID:7477729. |
these findings suggest that neuronal apoptosis is unlikely to be associated with post-natal development except in early post-natal germinal matrix, and that it may instead represent the end result of specific pathological processes, such as hiv-1 encephalitis. |
1995-11-27 |
2023-08-12 |
human |
| M N Peraldi, E Rondea. [Experimental models of acute kidney failure]. La Revue du praticien. vol 45. issue 13. 1995-11-03. PMID:7569687. |
more recent studies have emphasized the cellular and molecular events occurring during the course of arf, including changes in cytoskeleton and matrix proteins, apoptosis and the role of heat shock proteins. |
1995-11-03 |
2023-08-12 |
Not clear |
| J Wels. Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 72. issue 11-12. 1995-10-05. PMID:7654327. |
we have shown that mcf-7 cells treated with 100 nm 1,25(oh)2d3 exhibit characteristic apoptotic morphology (pyknotic nuclei, chromatin and cytoplasmic condensation, nuclear matrix protein reorganization) within 48 h. in the experiments reported here, we examined the interactions between 1,25(oh)2d3 and the antiestrogen 4-hydroxytamoxifen (tam), which also induces apoptosis in mcf-7 cells. |
1995-10-05 |
2023-08-12 |
Not clear |
| J Wels. Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 72. issue 11-12. 1995-10-05. PMID:7654327. |
combined treatment with 1,25(oh)2d3 and tam enhances the degree of apoptosis assessed using morphological markers that identify chromatin and nuclear matrix protein condensation. |
1995-10-05 |
2023-08-12 |
Not clear |
| M A Lagarkova, O V Iarovaia, S V Razi. Large-scale fragmentation of mammalian DNA in the course of apoptosis proceeds via excision of chromosomal DNA loops and their oligomers. The Journal of biological chemistry. vol 270. issue 35. 1995-10-04. PMID:7657590. |
furthermore, the patterns of dna long-range fragmentation in the cells undergoing apoptosis were indistinguishable from the patterns of dna cleavage into chromosomal loops by the high salt-insoluble topoisomerase ii of the nuclear matrix. |
1995-10-04 |
2023-08-12 |
mouse |
| D G Hoyt, R J Mannix, J M Rusnak, B R Pitt, J S Laz. Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells. The American journal of physiology. vol 269. issue 2 Pt 1. 1995-09-27. PMID:7653577. |
thus lps-induced apoptosis occurs in spaec after genotoxic damage and this process is suppressed by the extracellular matrix. |
1995-09-27 |
2023-08-12 |
Not clear |