| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A C Newby, S J Georg. Proliferation, migration, matrix turnover, and death of smooth muscle cells in native coronary and vein graft atherosclerosis. Current opinion in cardiology. vol 11. issue 6. 1997-03-10. PMID:8968671. |
it highlights the increasing importance attached to interactions between growth factors and components of the extracellular matrix in regulating migration and proliferation and the new roles assigned to apoptosis in these cells. |
1997-03-10 |
2023-08-12 |
Not clear |
| C H Lee, S K Lee, J G Chi, S C Park, S I Chung, M Saitoh, P Shrestha, M Mor. Immunohistochemical evaluation of transglutaminase C in tumours of salivary glands. European journal of cancer. Part B, Oral oncology. vol 32B. issue 6. 1997-03-07. PMID:9039224. |
transglutaminase c (tgase c), a family of ca(2+)-dependent enzymes and an essential component in the cross-linking of peptide bonds, has been found to be a marker of epithelial differentiation with a possible role in cellular apoptosis, extracellular matrix stabilisation and ca2+ binding, thereby having a potential role in tumour growth, differentiation and invasive behaviour. |
1997-03-07 |
2023-08-12 |
human |
| P Marchetti, D Decaudin, A Macho, N Zamzami, T Hirsch, S A Susin, G Kroeme. Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function. European journal of immunology. vol 27. issue 1. 1997-03-05. PMID:9022031. |
our data indicate that thymocyte apoptosis induced by diamide mimics natural apoptosis in the sense that mitochondrial transmembrane potential (delta psi(m)) disruption precedes nuclear chromatin degradation; that monovalent thiol-reactive compounds inhibit apoptosis induced by diamide, glucocorticoids, irradiation, and topoisomerase inhibition; that the critical thiols determining cell fate after exposure to diamide, glucocorticoids, or dna damage are likely to be located in the mitochondrial matrix; and that thiol oxidation and reduction are critical for apoptosis induction by some stimuli (glucocorticoids, dna damage), but not by fas/cd95 cross-linking. |
1997-03-05 |
2023-08-12 |
Not clear |
| N Goberdhan, C Dive, C H Streul. The role of the extracellular matrix and lactogenic hormones in mammary gland apoptosis. Biochemical Society transactions. vol 24. issue 3. 1997-02-26. PMID:8878892. |
the role of the extracellular matrix and lactogenic hormones in mammary gland apoptosis. |
1997-02-26 |
2023-08-12 |
Not clear |
| G Scott, L Cassidy, A Busacc. Fibronectin suppresses apoptosis in normal human melanocytes through an integrin-dependent mechanism. The Journal of investigative dermatology. vol 108. issue 2. 1997-02-13. PMID:9008226. |
recent reports show that components of the extracellular matrix function as cell survival factors through the suppression of apoptosis (programmed cell death). |
1997-02-13 |
2023-08-12 |
human |
| G Scott, L Cassidy, A Busacc. Fibronectin suppresses apoptosis in normal human melanocytes through an integrin-dependent mechanism. The Journal of investigative dermatology. vol 108. issue 2. 1997-02-13. PMID:9008226. |
in this report we show that attachment to fibronectin suppresses apoptosis of normal human fetal and neonatal melanocytes in vitro and that prevention of attachment to underlying matrix or attachment to poly-l-lysine is a potent inducer of apoptosis in melanocytes. |
1997-02-13 |
2023-08-12 |
human |
| C C Solorzano, R Ksontini, J H Pruitt, P J Hess, P D Edwards, A Kaibara, A Abouhamze, T Auffenberg, R E Galardy, J N Vauthey, E M Copeland, C K Edwards, G Y Lauwers, M Clare-Salzler, S L MacKay, L L Moldawer, D D Lazaru. Involvement of 26-kDa cell-associated TNF-alpha in experimental hepatitis and exacerbation of liver injury with a matrix metalloproteinase inhibitor. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 1. 1997-01-30. PMID:8977217. |
our studies suggest that cell-associated tnf-alpha plays a role in the hepatocellular necrosis and apoptosis that accompany d-galn/lps- or con a-induced hepatitis, and that matrix metalloproteinase inhibitors are ineffective in preventing this hepatic injury. |
1997-01-30 |
2023-08-12 |
mouse |
| E E Furlong, N K Keon, F D Thornton, T Rein, F Marti. Expression of a 74-kDa nuclear factor 1 (NF1) protein is induced in mouse mammary gland involution. Involution-enhanced occupation of a twin NF1 binding element in the testosterone-repressed prostate message-2/clusterin promoter. The Journal of biological chemistry. vol 271. issue 47. 1997-01-13. PMID:8939902. |
overlaying the cells with laminin-rich extracellular matrix suppressed the apoptosis and the expression of the 74-kda nf1 and, in the presence of lactogenic hormones, initiated milk protein gene expression and the expression of two of the lactation-associated nf1 proteins (68 and 46 kda). |
1997-01-13 |
2023-08-12 |
mouse |
| S Souchelnytskyi, P ten Dijke, K Miyazono, C H Heldi. Phosphorylation of Ser165 in TGF-beta type I receptor modulates TGF-beta1-induced cellular responses. The EMBO journal. vol 15. issue 22. 1997-01-09. PMID:8947046. |
mutations of ser165 in tbetar-i led to an increase in tgf-beta1-mediated growth inhibition and extracellular matrix formation, but, in contrast, to decreased tgf-beta1-induced apoptosis. |
1997-01-09 |
2023-08-12 |
Not clear |
| P L Jones, M Rabinovitc. Tenascin-C is induced with progressive pulmonary vascular disease in rats and is functionally related to increased smooth muscle cell proliferation. Circulation research. vol 79. issue 6. 1997-01-02. PMID:8943951. |
tenascin-c, an extracellular matrix glycoprotein prominent during tissue remodeling, has been linked to cell migration, proliferation, and apoptosis. |
1997-01-02 |
2023-08-12 |
rat |
| S M Frisch, K Vuori, D Kelaita, S Sick. A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA. The Journal of cell biology. vol 135. issue 5. 1997-01-02. PMID:8947558. |
the disruption of interactions between extracellular matrix and specific cognate integrins triggers apoptosis in epithelial cells, in a process termed "anoikis." |
1997-01-02 |
2023-08-12 |
Not clear |
| J M Hettasch, N Bandarenko, J L Burchette, T S Lai, J R Marks, Z A Haroon, K Peters, M W Dewhirst, J D Iglehart, C S Greenber. Tissue transglutaminase expression in human breast cancer. Laboratory investigation; a journal of technical methods and pathology. vol 75. issue 5. 1996-12-30. PMID:8941210. |
tissue transglutaminase (ttg) is postulated to play a role in apoptosis, cell adhesion, metastasis, and extracellular matrix (ecm) assembly. |
1996-12-30 |
2023-08-12 |
human |
| K Lee, B Lanske, A C Karaplis, J D Deeds, H Kohno, R A Nissenson, H M Kronenberg, G V Segr. Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895385. |
terminal differentiation of chondrocytes, which was characterized by cell hypertrophy, apoptosis (dna fragmentation and decreased bcl-2 mrna expression), and matrix mineralization, was more advanced in growth cartilage of pthrp(-/-), compared with pthrp(+/+) animals. |
1996-12-17 |
2023-08-12 |
mouse |
| T C Ho, L V Del Priore, H J Kapla. En bloc transfer of extracellular matrix in vitro. Current eye research. vol 15. issue 9. 1996-12-10. PMID:8921221. |
extracellular matrix (ecm) plays a major role in the development and regeneration of various epithelial cells including retinal pigment epithelium (rpe), and attachment to ecm inhibits rpe apoptosis. |
1996-12-10 |
2023-08-12 |
human |
| C A Delaney, B Tyrberg, L Bouwens, H Vaghef, B Hellman, D L Eiziri. Sensitivity of human pancreatic islets to peroxynitrite-induced cell dysfunction and death. FEBS letters. vol 394. issue 3. 1996-11-20. PMID:8830662. |
dna strand breaks in single human and rat islet cells are detectable after acute peroxynitrite exposure, followed by a decrease in islet cell survival after 1 h and 24 h. cell death appeared to occur via a toxic cell death mechanism (necrosis) rather than apoptosis, as suggested by vital staining and ultrastructural evidence of early membrane and organelle degradation, mitochondrial swelling and loss of matrix. |
1996-11-20 |
2023-08-12 |
human |
| J A Maier, D Morelli, S Ménard, M I Colnaghi, A Balsar. Tumor-necrosis-factor-induced fibroblast growth factor-1 acts as a survival factor in a transformed endothelial cell line. The American journal of pathology. vol 149. issue 3. 1996-10-17. PMID:8780398. |
endothelial cells undergo apoptosis after withdrawal of growth factors, alterations in the extracellular matrix, or exposure to cytokines. |
1996-10-17 |
2023-08-12 |
human |
| C A Casiano, S J Martin, D R Green, E M Ta. Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis. The Journal of experimental medicine. vol 184. issue 2. 1996-09-23. PMID:8760832. |
several of the cleaved autoantigens are involved in ensuring the integrity and proper conformation of dna in the nucleus through interactions with the nuclear matrix, suggesting the possibility that their cleavage may contribute to the collapse of nuclear structure during apoptosis. |
1996-09-23 |
2023-08-12 |
human |
| S M Frisch, K Vuori, E Ruoslahti, P Y Chan-Hu. Control of adhesion-dependent cell survival by focal adhesion kinase. The Journal of cell biology. vol 134. issue 3. 1996-09-12. PMID:8707856. |
the interactions of integrins with extracellular matrix proteins can activate focal adhesion kinase (fak) and suppress apoptosis in normal epithelial and endothelial cells; this subset of apoptosis has been termed "anoikis." |
1996-09-12 |
2023-08-12 |
mouse |
| M O Boluyt, O H Bing, E G Lakatt. The ageing spontaneously hypertensive rat as a model of the transition from stable compensated hypertrophy to heart failure. European heart journal. vol 16 Suppl N. 1996-08-21. PMID:8682057. |
research opportunities include investigation of apoptosis as a mechanism of cell loss, delineation of the regulatory roles of tgf-beta 1 and the renin-angiotensin-aldosterone system in matrix accumulation, and studies of proteinase cascades that regulate matrix remodelling. |
1996-08-21 |
2023-08-12 |
rat |
| L Borge, S Demignot, M Adolph. Type II transglutaminase expression in rabbit articular chondrocytes in culture: relation with cell differentiation, cell growth, cell adhesion and cell apoptosis. Biochimica et biophysica acta. vol 1312. issue 2. 1996-08-09. PMID:8672533. |
depending on the cell type studied, the involvement of type ii transglutaminase (tgase) has been proposed in almost any event of the cell life such as differentiation, apoptosis, growth, aging, cell morphology and adhesion, metastatic capacity or extracellular matrix stabilization. |
1996-08-09 |
2023-08-12 |
rabbit |