| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seiji Shioda, Hirokazu Ohtaki, Tomoya Nakamachi, Kenji Dohi, Jun Watanabe, Shigeo Nakajo, Satoru Arata, Shinji Kitamura, Hiromi Okuda, Fumiko Takenoya, Yoshitaka Kitamur. Pleiotropic functions of PACAP in the CNS: neuroprotection and neurodevelopment. Annals of the New York Academy of Sciences. vol 1070. 2006-09-25. PMID:16888224. |
pacap prevents ischemic delayed neuronal cell death (apoptosis) in the hippocampus. |
2006-09-25 |
2023-08-12 |
mouse |
| B L Williams, W I Lipki. Endoplasmic reticulum stress and neurodegeneration in rats neonatally infected with borna disease virus. Journal of virology. vol 80. issue 17. 2006-09-25. PMID:16912310. |
borna disease virus infection of neonatal rats results in a characteristic behavioral syndrome and apoptosis of subsets of neurons in the hippocampus and cerebellum (neonatal borna disease [nbd]). |
2006-09-25 |
2023-08-12 |
rat |
| Rui Silva, Jie Lu, Yan Wu, Luis Martins, Osborne F X Almeida, Nuno Sous. Mapping cellular gains and losses in the postnatal dentate gyrus: implications for psychiatric disorders. Experimental neurology. vol 200. issue 2. 2006-09-21. PMID:16624303. |
neurogenesis and apoptosis occur contemporaneously in the postnatal hippocampal dentate gyrus and have been implicated in mood and cognitive disorders. |
2006-09-21 |
2023-08-12 |
rat |
| Rui Silva, Jie Lu, Yan Wu, Luis Martins, Osborne F X Almeida, Nuno Sous. Mapping cellular gains and losses in the postnatal dentate gyrus: implications for psychiatric disorders. Experimental neurology. vol 200. issue 2. 2006-09-21. PMID:16624303. |
interestingly, apoptosis was higher in the left hippocampus. |
2006-09-21 |
2023-08-12 |
rat |
| Rui Silva, Jie Lu, Yan Wu, Luis Martins, Osborne F X Almeida, Nuno Sous. Mapping cellular gains and losses in the postnatal dentate gyrus: implications for psychiatric disorders. Experimental neurology. vol 200. issue 2. 2006-09-21. PMID:16624303. |
these results raise intriguing new questions regarding the coordinated regulation of hippocampal neurogenesis and apoptosis since the two processes apparently share common regulatory factors. |
2006-09-21 |
2023-08-12 |
rat |
| Rui Silva, Jie Lu, Yan Wu, Luis Martins, Osborne F X Almeida, Nuno Sous. Mapping cellular gains and losses in the postnatal dentate gyrus: implications for psychiatric disorders. Experimental neurology. vol 200. issue 2. 2006-09-21. PMID:16624303. |
in addition, these findings open questions with respect to the functional significance of topographical gradients in neurogenesis and apoptosis in the context of the etiopathogenesis of neuropsychiatric diseases and the reported dependence on the efficacy of therapeutic agents on the generation of new hippocampal neurons. |
2006-09-21 |
2023-08-12 |
rat |
| YueMei Zhang, Bhagu R Bhavnan. Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens. BMC neuroscience. vol 7. 2006-09-20. PMID:16776830. |
our previous studies have shown that depending on the neuronal cell type, glutamate-induced apoptotic cell death was associated with regulation of genes such as bcl-2, bax, and/or caspase-3 and mitochondrial cytochrome c. to further delineate the intracellular mechanisms, we have investigated the role of calpain, an important calcium-dependent protease thought to be involved in apoptosis along with mitochondrial apoptosis inducing factor (aif) and caspase-3 in primary cortical cells and a mouse hippocampal cell line ht22. |
2006-09-20 |
2023-08-12 |
mouse |
| Helen M Marriott, David H Dockrel. Streptococcus pneumoniae: the role of apoptosis in host defense and pathogenesis. The international journal of biochemistry & cell biology. vol 38. issue 11. 2006-09-18. PMID:16844403. |
microbial factors and host factors combine in causing apoptosis in the brain, with hippocampal neurons being particularly susceptible. |
2006-09-18 |
2023-08-12 |
Not clear |
| Xu Cui, Pingping Zuo, Qing Zhang, Xuekun Li, Yazhuo Hu, Jiangang Long, Lester Packer, Jiankang Li. Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid. Journal of neuroscience research. vol 83. issue 8. 2006-09-08. PMID:16555301. |
to investigate the mechanisms of neurodegeneration in this model, we studied cognitive function, hippocampal neuronal apoptosis and neurogenesis, and peripheral oxidative stress biomarkers and also the protective effects of the antioxidant r-alpha-lipoic acid. |
2006-09-08 |
2023-08-12 |
mouse |
| Xu Cui, Pingping Zuo, Qing Zhang, Xuekun Li, Yazhuo Hu, Jiangang Long, Lester Packer, Jiankang Li. Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid. Journal of neuroscience research. vol 83. issue 8. 2006-09-08. PMID:16555301. |
chronic systemic exposure of mice to d-galactose (100 mg/kg, s.c., 7 weeks) induced a spatial memory deficit, an increase in cell karyopyknosis, apoptosis, and caspase-3 protein levels in hippocampal neurons, a decrease in the number of new neurons in the subgranular zone in the dentate gyrus, a reduction of migration of neural progenitor cells, and an increase in death of newly formed neurons in the granular cell layer. |
2006-09-08 |
2023-08-12 |
mouse |
| Natalie N Rizk, José A Rafols, Joseph C Dunba. Cerebral ischemia-induced apoptosis and necrosis in normal and diabetic rats: effects of insulin and C-peptide. Brain research. vol 1096. issue 1. 2006-09-08. PMID:16729987. |
two brain areas, the sensori-motor cortex (layers-5 and 6) and the ca1 and ca3 sectors (pyramidal cell layers) of the hippocampus, were analyzed for apoptosis using tunel and caspase-3 immunoreactivity. |
2006-09-08 |
2023-08-12 |
rat |
| Susan G Dorsey, Cynthia L Renn, Laura Carim-Todd, Colleen A Barrick, Linda Bambrick, Bruce K Krueger, Christopher W Ward, Lino Tessaroll. In vivo restoration of physiological levels of truncated TrkB.T1 receptor rescues neuronal cell death in a trisomic mouse model. Neuron. vol 51. issue 1. 2006-08-31. PMID:16815329. |
in the trisomy 16 (ts16) mouse there is increased apoptosis in the cortex, and hippocampal neurons undergo accelerated cell death that cannot be rescued by administration of brain-derived neurotrophic factor (bdnf). |
2006-08-31 |
2023-08-12 |
mouse |
| Sergio Andrés, Sergio Cárdenas, Claudio Parra, Javier Bravo, Monika Greiner, Paulina Rojas, Paola Morales, Hernán Lara, Jenny Fiedle. Effects of long-term adrenalectomy on apoptosis and neuroprotection in the rat hippocampus. Endocrine. vol 29. issue 2. 2006-08-30. PMID:16785605. |
effects of long-term adrenalectomy on apoptosis and neuroprotection in the rat hippocampus. |
2006-08-30 |
2023-08-12 |
rat |
| Sergio Andrés, Sergio Cárdenas, Claudio Parra, Javier Bravo, Monika Greiner, Paulina Rojas, Paola Morales, Hernán Lara, Jenny Fiedle. Effects of long-term adrenalectomy on apoptosis and neuroprotection in the rat hippocampus. Endocrine. vol 29. issue 2. 2006-08-30. PMID:16785605. |
however, no studies exist correlating the effect of long-term adrenalectomy (30 d) on the hippocampus in terms of extent of apoptosis and the levels of proteins related to an apoptotic cascade. |
2006-08-30 |
2023-08-12 |
rat |
| Chun-Ho Park, Mariko Kondo, Satoshi Inoue, Akira Noguchi, Toshifumi Oyamada, Hiroyasu Yoshikawa, Akio Yamad. The histopathogenesis of paralytic rabies in six-week-old C57BL/6J mice following inoculation of the CVS-11 strain into the right triceps surae muscle. The Journal of veterinary medical science. vol 68. issue 6. 2006-08-22. PMID:16820716. |
at 4 days pi, severe apoptosis and dna fragmentation were observed in the hippocampus and cerebral cortex. |
2006-08-22 |
2023-08-12 |
mouse |
| Zhi-Xian Yang, Jiong Qin, Xing-Zhi Chang, Ying Han, Ying Sha. [Effect of carbon monoxide and nitric oxide on the apoptosis of hippocampal neurons in rats with febrile seizures]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 8. issue 3. 2006-08-18. PMID:16787598. |
[effect of carbon monoxide and nitric oxide on the apoptosis of hippocampal neurons in rats with febrile seizures]. |
2006-08-18 |
2023-08-12 |
rat |
| Zhi-Xian Yang, Jiong Qin, Xing-Zhi Chang, Ying Han, Ying Sha. [Effect of carbon monoxide and nitric oxide on the apoptosis of hippocampal neurons in rats with febrile seizures]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 8. issue 3. 2006-08-18. PMID:16787598. |
this study examined the effects of the two systems on the apoptosis of hippocampal neurons in rats with recurrent fs. |
2006-08-18 |
2023-08-12 |
rat |
| Nesar Akanda, Fredrik Elinde. Biophysical properties of the apoptosis-inducing plasma membrane voltage-dependent anion channel. Biophysical journal. vol 90. issue 12. 2006-07-27. PMID:16581845. |
in a recent study we found that a voltage-dependent anion channel in the plasma membrane (vdacpl) of neuronal hippocampal cell line (ht22) cells was activated during apoptosis and that channel block prevented apoptosis. |
2006-07-27 |
2023-08-12 |
Not clear |
| Hong-Gang Zhao, Wen-Bin Li, Qing-Jun Li, Xiao-Ling Chen, Hui-Qing Liu, Rong-Fang Feng, Jie A. Limb ischemic preconditioning attenuates apoptosis of pyramidal neurons in the CA1 hippocampus induced by cerebral ischemia-reperfusion in rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 56. issue 3. 2006-07-21. PMID:15224159. |
limb ischemic preconditioning attenuates apoptosis of pyramidal neurons in the ca1 hippocampus induced by cerebral ischemia-reperfusion in rats. |
2006-07-21 |
2023-08-12 |
rat |
| Hong-Gang Zhao, Wen-Bin Li, Qing-Jun Li, Xiao-Ling Chen, Hui-Qing Liu, Rong-Fang Feng, Jie A. Limb ischemic preconditioning attenuates apoptosis of pyramidal neurons in the CA1 hippocampus induced by cerebral ischemia-reperfusion in rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 56. issue 3. 2006-07-21. PMID:15224159. |
the purpose of this study was to investigate the effects of limb ischemic preconditioning (lip) on apoptosis of pyramidal neurons in the ca1 hippocampus induced by global cerebral ischemia-reperfusion in rats. |
2006-07-21 |
2023-08-12 |
rat |