| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jaetaek Kim, Ji-Hyun Ahn, Jeong-Hun Kim, Young-Suk Yu, Ho-Shik Kim, Joohun Ha, Soon-Hyun Shinn, Yeon-Sahng O. Fenofibrate regulates retinal endothelial cell survival through the AMPK signal transduction pathway. Experimental eye research. vol 84. issue 5. 2007-07-11. PMID:17343853. |
this inhibition of apoptosis by fenofibrate was not altered by peroxisome proliferator-activated receptor alpha (pparalpha) antagonist mk 886, and selective agonist for pparalpha, wy-14643 had no beneficial effects on serum deprivation-induced cell death. |
2007-07-11 |
2023-08-12 |
human |
| Jennifer Cook-Easterwood, Lawrence D Middaugh, William C Griffin, Irfan Khan, William R Tyo. Highly active antiretroviral therapy of cognitive dysfunction and neuronal abnormalities in SCID mice with HIV encephalitis. Experimental neurology. vol 205. issue 2. 2007-07-10. PMID:17442303. |
these results suggest that viral load, astrogliosis, tnf- alpha and apoptosis are not prominent in the pathogenesis of early functional deficits related to decreased map-2 expression or cognitive dysfunction in hive in scid mice. |
2007-07-10 |
2023-08-12 |
mouse |
| Mark W Hansberger, Jacquelyn A Campbell, Pranav Danthi, Pia Arrate, Kevin N Pennington, Kenneth B Marcu, Dean W Ballard, Terence S Dermod. IkappaB kinase subunits alpha and gamma are required for activation of NF-kappaB and induction of apoptosis by mammalian reovirus. Journal of virology. vol 81. issue 3. 2007-07-06. PMID:17121808. |
ikappab kinase subunits alpha and gamma are required for activation of nf-kappab and induction of apoptosis by mammalian reovirus. |
2007-07-06 |
2023-08-12 |
mouse |
| Andreas Schober, Alma Zerneck. Chemokines in vascular remodeling. Thrombosis and haemostasis. vol 97. issue 5. 2007-07-03. PMID:17479183. |
in contrast, stromal cell-derived factor (sdf)-1 alpha and its receptor cxc motif receptor 4 (cxcr4) are centrally involved in the neointimal recruitment of smc progenitor cells (spcs), presumably in response to smc apoptosis, in restenosis and cav. |
2007-07-03 |
2023-08-12 |
Not clear |
| Alexandra Rolaki, George Coukos, Dimitris Loutradis, Horace M DeLisser, Christos Coutifaris, Antonis Makrigiannaki. Luteogenic hormones act through a vascular endothelial growth factor-dependent mechanism to up-regulate alpha 5 beta 1 and alpha v beta 3 integrins, promoting the migration and survival of human luteinized granulosa cells. The American journal of pathology. vol 170. issue 5. 2007-06-26. PMID:17456762. |
lastly, expression of alpha(5)beta(1) and alpha(v)beta(3) mediated adhesion to fn, facilitated migration, and prevented apoptosis. |
2007-06-26 |
2023-08-12 |
human |
| b' Marie-Jos\\xc3\\xa8phe Leroy, Emmanuelle Dallot, Isabelle Czerkiewicz, Thomas Schmitz, Michelle Breuiller-Fouch\\xc3\\xa. Inflammation of choriodecidua induces tumor necrosis factor alpha-mediated apoptosis of human myometrial cells. Biology of reproduction. vol 76. issue 5. 2007-06-20. PMID:17215489.' |
the present study investigated the ability of human choriodecidua to induce myometrial cell apoptosis through the secretion of tumor necrosis factor alpha (tnf). |
2007-06-20 |
2023-08-12 |
human |
| Vasyl' F Chekhun, Nataliya Yu Lukyanova, Olga Kovalchuk, Volodymyr P Tryndyak, Igor P Pogribn. Epigenetic profiling of multidrug-resistant human MCF-7 breast adenocarcinoma cells reveals novel hyper- and hypomethylated targets. Molecular cancer therapeutics. vol 6. issue 3. 2007-06-20. PMID:17363502. |
a detailed analysis of hypo- and hypermethylated dna sequences revealed that the acquisition of drug-resistant phenotype of mcf-7 cells to dox and cisddp, in addition to specific alterations induced by a particular drug only, was characterized by three major common mechanisms: dysfunction of genes involved in estrogen metabolism (sulfatase 2 and estrogen receptor alpha), apoptosis (p73, alpha-tubulin, bcl2-antagonist of cell death, tissue transglutaminase 2 and forkhead box protein k1), and cell-cell contact (leptin, stromal cell-derived factor receptor 1, activin a receptor e-cadherin) and showed that two opposing hypo- and hypermethylation processes may enhance and complement each other in the disruption of these pathways. |
2007-06-20 |
2023-08-12 |
human |
| N V Gibanova, T V Rakitina, V M Lipkin, I A Kostanya. Granulocyte differentiation inducer, hexapeptide HLDF-6, decreases cytotoxic effect of tumor necrosis factor on HL-60 cell line. Biochemistry. Biokhimiia. vol 72. issue 1. 2007-06-18. PMID:17309437. |
the effect of hexapeptide hldf-6, the granulocytic differentiation inducer, on the tumor necrosis factor alpha (tnf-alpha)-induced differentiation and apoptosis of human promyelocytic leukemia hl-60 cells has been investigated. |
2007-06-18 |
2023-08-12 |
human |
| Yasuhisa Oida, Began Gopalan, Ryo Miyahara, Cynthia D Branch, Paul Chiao, Sunil Chada, Rajagopal Rames. Inhibition of nuclear factor-kappaB augments antitumor activity of adenovirus-mediated melanoma differentiation-associated gene-7 against lung cancer cells via mitogen-activated protein kinase kinase kinase 1 activation. Molecular cancer therapeutics. vol 6. issue 4. 2007-06-12. PMID:17431123. |
an enhanced growth arrest and apoptosis was observed in ad-mda7-treated h1299-dni kappa b alpha compared with h1299-neo cells. |
2007-06-12 |
2023-08-12 |
human |
| Chih-Chiun Chen, Jennifer L Young, Ricardo I Monzon, Ningyu Chen, Viktor Todorović, Lester F La. Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling. The EMBO journal. vol 26. issue 5. 2007-06-11. PMID:17318182. |
ccn1 acts through binding to integrins alpha(v)beta(5), alpha(6)beta(1), and syndecan-4, triggering the generation of reactive oxygen species (ros) through a rac1-dependent mechanism via 5-lipoxygenase and the mitochondria, leading to the biphasic activation of jnk necessary for apoptosis. |
2007-06-11 |
2023-08-12 |
mouse |
| Weiling Zhao, Samy Iskandar, Mitra Kooshki, Jessica G Sharpe, Valerie Payne, Mike E Robbin. Knocking out peroxisome proliferator-activated receptor (PPAR) alpha inhibits radiation-induced apoptosis in the mouse kidney through activation of NF-kappaB and increased expression of IAPs. Radiation research. vol 167. issue 5. 2007-06-08. PMID:17474796. |
knocking out peroxisome proliferator-activated receptor (ppar) alpha inhibits radiation-induced apoptosis in the mouse kidney through activation of nf-kappab and increased expression of iaps. |
2007-06-08 |
2023-08-12 |
mouse |
| Yimin Qin, Sogyong Auh, Lyubov Blokh, Catherine Long, Isabelle Gagnon, Kimm J Haman. TNF-alpha induces transient resistance to Fas-induced apoptosis in eosinophilic acute myeloid leukemia cells. Cellular & molecular immunology. vol 4. issue 1. 2007-06-01. PMID:17349210. |
tumor necrosis factor alpha (tnf-alpha) has been recognized as an activator of nuclear factor kappab (nf-kappab), a factor implicated in the protection of many cell types from apoptosis. |
2007-06-01 |
2023-08-12 |
Not clear |
| M Hamada, T Sumi, S Iwai, M Nakazawa, Y Yur. Induction of endonuclease G-mediated apopotosis in human oral squamous cell carcinoma cells by protein kinase C inhibitor safingol. Apoptosis : an international journal on programmed cell death. vol 11. issue 1. 2007-05-31. PMID:16374540. |
these results suggest that pkc alpha inhibitor safingol induces an endonuclease g- mediated apoptosis in a caspase-independent manner. |
2007-05-31 |
2023-08-12 |
human |
| M Guo, L-P Song, Y Jiang, W Liu, Y Yu, G-Q Che. Hypoxia-mimetic agents desferrioxamine and cobalt chloride induce leukemic cell apoptosis through different hypoxia-inducible factor-1alpha independent mechanisms. Apoptosis : an international journal on programmed cell death. vol 11. issue 1. 2007-05-31. PMID:16374551. |
the results show that both of them induce these leukemic cells to undergo apoptosis with a loss of mitochondrial transmembrane potentials (deltapsi m), the activation of caspase-3/8 and the cleavage of anti-apoptotic protein mcl-1, together with the accumulation of hypoxia-inducible factor-1 alpha (hif-1alpha) protein, a critical regulator for the cellular response to hypoxia. |
2007-05-31 |
2023-08-12 |
Not clear |
| Cristina Cellerai, Alexandre Harari, Florence Vallelian, Onur Boyman, Giuseppe Pantale. Functional and phenotypic characterization of tetanus toxoid-specific human CD4+ T cells following re-immunization. European journal of immunology. vol 37. issue 4. 2007-05-25. PMID:17372991. |
for cd8(+ )t cells, successful generation of memory cells has been linked to il-7 receptor alpha (il-7ralpha) expression, suggesting a role for il-7 signaling, which in turn is important for preventing t cell apoptosis. |
2007-05-25 |
2023-08-12 |
human |
| Kenji Yanagisawa, Satoshi Yasuda, Masahiro Kai, Shin-ichi Imai, Keiko Yamada, Toshiharu Yamashita, Kowichi Jimbow, Hideo Kanoh, Fumio Sakan. Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation. Biochimica et biophysica acta. vol 1771. issue 4. 2007-05-24. PMID:17276726. |
diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through nf-kappab activation. |
2007-05-24 |
2023-08-12 |
human |
| Ariel U Spencer, Hua Yang, Emir Q Haxhija, Barbara E Wildhaber, Joel K Greenson, Daniel H Teitelbau. Reduced severity of a mouse colitis model with angiotensin converting enzyme inhibition. Digestive diseases and sciences. vol 52. issue 4. 2007-05-24. PMID:17342403. |
ulcerative colitis is characterized by elevated rates of epithelial cell apoptosis, and an up-regulation of pro-apoptotic cytokines including tumor necrosis factor alpha (tnf-alpha). |
2007-05-24 |
2023-08-12 |
mouse |
| M Kilic, H Kasperczyk, S Fulda, K-M Debati. Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance. Oncogene. vol 26. issue 14. 2007-05-23. PMID:17043658. |
role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance. |
2007-05-23 |
2023-08-12 |
Not clear |
| James D Yager, Jin Q Che. Mitochondrial estrogen receptors--new insights into specific functions. Trends in endocrinology and metabolism: TEM. vol 18. issue 3. 2007-05-23. PMID:17324583. |
estrogen receptor (er) alpha and erbeta are present in mitochondria but little is known about their contribution to the overall constellation of cellular responses to 17beta-estradiol, which inhibits the early stages of apoptosis through membrane and mitochondrial, but not nuclear, er signaling pathways. |
2007-05-23 |
2023-08-12 |
Not clear |
| A Lamberti, O Longo, M Marra, P Tagliaferri, E Bismuto, A Fiengo, C Viscomi, A Budillon, U R Rapp, E Wang, S Venuta, A Abbruzzese, P Arcari, M Caragli. C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A. Cell death and differentiation. vol 14. issue 5. 2007-05-23. PMID:17332776. |
interferon alpha (ifnalpha) induces both apoptosis and a counteracting epidermal growth factor erk-dependent survival response in cancer cells. |
2007-05-23 |
2023-08-12 |
human |