| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji Young Kim, Chan Hyung Kim, Eun Young Lee, Je Hoon Se. Alpha B-Crystallin Overexpression Protects Oligodendrocyte Precursor Cells Against Oxidative Stress-Induced Apoptosis Through the Akt Pathway. Journal of molecular neuroscience : MN. vol 70. issue 5. 2021-01-04. PMID:31970633. |
alpha b-crystallin overexpression protects oligodendrocyte precursor cells against oxidative stress-induced apoptosis through the akt pathway. |
2021-01-04 |
2023-08-13 |
Not clear |
| Ahdeah Pajoohesh-Ganji, Robert H Mille. Targeted Oligodendrocyte Apoptosis in Optic Nerve Leads to Persistent Demyelination. Neurochemical research. vol 45. issue 3. 2020-12-21. PMID:30848441. |
targeted oligodendrocyte apoptosis in optic nerve leads to persistent demyelination. |
2020-12-21 |
2023-08-13 |
mouse |
| Ahdeah Pajoohesh-Ganji, Robert H Mille. Targeted Oligodendrocyte Apoptosis in Optic Nerve Leads to Persistent Demyelination. Neurochemical research. vol 45. issue 3. 2020-12-21. PMID:30848441. |
delivery of an inducer of oligodendrocyte apoptosis by intravitreous injection minimizes trauma to the optic nerve and allows for the assessment of oligodendrocyte death in the absence of injury related factors. |
2020-12-21 |
2023-08-13 |
mouse |
| Ahdeah Pajoohesh-Ganji, Robert H Mille. Targeted Oligodendrocyte Apoptosis in Optic Nerve Leads to Persistent Demyelination. Neurochemical research. vol 45. issue 3. 2020-12-21. PMID:30848441. |
unlike in other regions of the murine cns, where local demyelination stimulates activation of local oligodendrocyte precursors and remyelination, optic nerve demyelination induced by oligodendrocyte apoptosis fails to recover and results in persistent areas of myelin loss. |
2020-12-21 |
2023-08-13 |
mouse |
| Yasheng Yan, Shigang Qiao, Chika Kikuchi, Ivan Zaja, Sarah Logan, Congshan Jiang, Thiago Arzua, Xiaowen Ba. Propofol Induces Apoptosis of Neurons but Not Astrocytes, Oligodendrocytes, or Neural Stem Cells in the Neonatal Mouse Hippocampus. Brain sciences. vol 7. issue 10. 2020-10-01. PMID:29036908. |
to identify vulnerable cells undergoing apoptosis following propofol exposure, brain sagittal sections were co-stained with antibodies against an apoptosis marker along with neuron, astrocyte, oligodendrocyte, or nsc markers using immunofluorescence staining. |
2020-10-01 |
2023-08-13 |
mouse |
| Takeshi Imai, Hiroyuki Katoh, Kaori Suyama, Masahiro Kuroiwa, Sho Yanagisawa, Masahiko Watanab. Amiloride Promotes Oligodendrocyte Survival and Remyelination after Spinal Cord Injury in Rats. Journal of clinical medicine. vol 7. issue 3. 2020-10-01. PMID:29510579. |
oligodendrocyte precursor cells (opcs) actively proliferate after sci, but many of these cells undergo apoptosis. |
2020-10-01 |
2023-08-13 |
rat |
| Nathalie Laflamme, Giulia Cisbani, Paul Préfontaine, Younes Srour, Jordan Bernier, Marie-Kim St-Pierre, Marie-Ève Tremblay, Serge Rives. mCSF-Induced Microglial Activation Prevents Myelin Loss and Promotes Its Repair in a Mouse Model of Multiple Sclerosis. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30018535. |
demyelinated lesions are deeply associated with oligodendrocyte apoptosis and a robust inflammatory response. |
2020-10-01 |
2023-08-13 |
mouse |
| Jiao Mu, Meiyu Li, Tingting Wang, Xiujuan Li, Meiling Bai, Guohui Zhang, Jiming Kon. Myelin Damage in Diffuse Axonal Injury. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:30941005. |
increased apoptosis of mature oligodendrocyte, as depicted by its marker cc-1, was observed. |
2020-09-30 |
2023-08-13 |
rat |
| Ying Wang, Li Guo, Jueqiong Wang, Wei Shi, Zhilun Xia, Bin L. Necrostatin-1 ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by suppressing apoptosis and necroptosis of oligodendrocyte precursor cells. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31611942. |
necrostatin-1 ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by suppressing apoptosis and necroptosis of oligodendrocyte precursor cells. |
2020-09-30 |
2023-08-13 |
mouse |
| Ying Wang, Li Guo, Jueqiong Wang, Wei Shi, Zhilun Xia, Bin L. Necrostatin-1 ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by suppressing apoptosis and necroptosis of oligodendrocyte precursor cells. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31611942. |
ms pathogenesis occurs via multiple mechanisms, and is mediated in part by oligodendrocyte apoptosis and a robust inflammatory response. |
2020-09-30 |
2023-08-13 |
mouse |
| Ying Wang, Li Guo, Jueqiong Wang, Wei Shi, Zhilun Xia, Bin L. Necrostatin-1 ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by suppressing apoptosis and necroptosis of oligodendrocyte precursor cells. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31611942. |
nec-1 also suppressed tnfα + zvad-fmk-induced apoptosis and necroptosis in primary oligodendrocyte precursor cells. |
2020-09-30 |
2023-08-13 |
mouse |
| Xiaohua Li, Changhong Ren, Sijie Li, Rongrong Han, Jinhuan Gao, Qingjian Huang, Kunlin Jin, Yinghao Luo, Xunming J. Limb Remote Ischemic Conditioning Promotes Myelination by Upregulating PTEN/Akt/mTOR Signaling Activities after Chronic Cerebral Hypoperfusion. Aging and disease. vol 8. issue 4. 2020-09-29. PMID:28840054. |
cognitive function, oligodendrocyte counts, myelin density, apoptosis and proliferation activity, as well as pten/akt/mtor signaling activity were determined 4 weeks after treatment. |
2020-09-29 |
2023-08-13 |
rat |
| Johannes van der Merwe, Lennart van der Veeken, Sebastiano Ferraris, Willy Gsell, Uwe Himmelreich, Jaan Toelen, Sebastien Ourselin, Andrew Melbourne, Tom Vercauteren, Jan Depres. Early neuropathological and neurobehavioral consequences of preterm birth in a rabbit model. Scientific reports. vol 9. issue 1. 2020-09-21. PMID:30837582. |
neuropathological assessments for neuron and oligodendrocyte quantification, astrogliosis, apoptosis and cellular proliferation were performed. |
2020-09-21 |
2023-08-13 |
rabbit |
| Johannes van der Merwe, Lennart van der Veeken, Sebastiano Ferraris, Willy Gsell, Uwe Himmelreich, Jaan Toelen, Sebastien Ourselin, Andrew Melbourne, Tom Vercauteren, Jan Depres. Early neuropathological and neurobehavioral consequences of preterm birth in a rabbit model. Scientific reports. vol 9. issue 1. 2020-09-21. PMID:30837582. |
preterm birth was associated with a motoric (posture instability, abnormal gait and decreased locomotion) and partial sensory (less pain responsiveness and failing righting reflex) deficits that coincided with global lower neuron densities, less oligodendrocyte precursors, increased apoptosis and less proliferation. |
2020-09-21 |
2023-08-13 |
rabbit |
| Hiroko Nobuta, Nan Yang, Yi Han Ng, Samuele G Marro, Khalida Sabeur, Manideep Chavali, John H Stockley, David W Killilea, Patrick B Walter, Chao Zhao, Philip Huie, Steven A Goldman, Arnold R Kriegstein, Robin J M Franklin, David H Rowitch, Marius Werni. Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. Cell stem cell. vol 25. issue 4. 2020-09-21. PMID:31585094. |
iron chelation rescued mutant oligodendrocyte apoptosis, survival, and differentiationin vitro, and post-transplantation in vivo. |
2020-09-21 |
2023-08-13 |
mouse |
| Hiroko Nobuta, Nan Yang, Yi Han Ng, Samuele G Marro, Khalida Sabeur, Manideep Chavali, John H Stockley, David W Killilea, Patrick B Walter, Chao Zhao, Philip Huie, Steven A Goldman, Arnold R Kriegstein, Robin J M Franklin, David H Rowitch, Marius Werni. Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. Cell stem cell. vol 25. issue 4. 2020-09-21. PMID:31585094. |
finally, systemic treatment of plp1 mutant jimpy mice with deferiprone, a small molecule iron chelator, reduced oligodendrocyte apoptosis and enabled myelin formation. |
2020-09-21 |
2023-08-13 |
mouse |
| Gábor Kriszta, Balázs Nemes, Zoltán Sándor, Péter Ács, Sámuel Komoly, Zoltán Berente, Kata Bölcskei, Erika Pinté. Investigation of Cuprizone-Induced Demyelination in mGFAP-Driven Conditional Transient Receptor Potential Ankyrin 1 (TRPA1) Receptor Knockout Mice. Cells. vol 9. issue 1. 2020-09-03. PMID:31905673. |
genetic deletion of trpa1 was shown to attenuate cuprizone-induced oligodendrocyte apoptosis and myelin loss in mice. |
2020-09-03 |
2023-08-13 |
mouse |
| Åsa Jungner, Suvi Vallius Kvist, Olga Romantsik, Matteo Bruschettini, Claes Ekström, Ivo Bendix, Josephine Herz, Ursula Felderhoff-Mueser, Adnan Bibic, René In Apos T Zandt, Magnus Gram, David Le. White Matter Brain Development after Exposure to Circulating Cell-Free Hemoglobin and Hyperoxia in a Rat Pup Model. Developmental neuroscience. vol 41. issue 3-4. 2020-06-30. PMID:31991415. |
postnatal day 6 rat pups were injected intraperitoneally with cell-free hb or vehicle and exposed to hyperoxia (fio2 = 0.8) or normoxia (fio2 = 0.21) for 24 h. we evaluated apoptosis, myelination, and oligodendrocyte maturation with immunohistochemistry, gene and protein analyses, and in vivo diffusion tensor magnetic resonance imaging (mri). |
2020-06-30 |
2023-08-13 |
rat |
| Chiara Grasselli, Daniela Ferrari, Cristina Zalfa, Matias Soncini, Gianluigi Mazzoccoli, Fabio A Facchini, Laura Marongiu, Francesca Granucci, Massimiliano Copetti, Angelo Luigi Vescovi, Francesco Peri, Lidia De Filippi. Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation. Cell death & disease. vol 9. issue 3. 2020-04-06. PMID:29449625. |
tlr4 activation promotes neuronal and oligodendrocyte differentiation and/or survival while tlr4 inhibition leads to increased apoptosis. |
2020-04-06 |
2023-08-13 |
mouse |
| Robert P Lisak, Liljana Nedelkoska, Joyce A Benjamin. Sigma-1 receptor agonists as potential protective therapies in multiple sclerosis. Journal of neuroimmunology. vol 342. 2020-03-24. PMID:32179326. |
we show that anavex2-73 protects oligodendroglia (ol) and oligodendroglial precursors (opc) from apoptosis, excitotoxicity, reactive oxygen species (ros) and quinolinic acid (qa), associated with inflammation. |
2020-03-24 |
2023-08-13 |
Not clear |