| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ignacio Valenzuela, David Basurto, Yannick Regin, Andre Gie, Lennart van der Veeken, Simen Vergote, Emma Muñoz-Moreno, Bartosz Leszczynski, Birger Tielemans, Greetje Vande Velde, Jan Deprest, Johannes van der Merw. Placental vascular alterations are associated with early neurodevelopmental and pulmonary impairment in the rabbit fetal growth restriction model. Scientific reports. vol 12. issue 1. 2022-11-17. PMID:36385147. |
neuropathological assessment included multiregional quantification of neuron density, apoptosis, astrogliosis, cellular proliferation, and oligodendrocyte progenitors. |
2022-11-17 |
2023-08-14 |
human |
| Yanmin Gao, Di Xie, Yang Wang, Lei Niu, Hua Jian. Short-Chain Fatty Acids Reduce Oligodendrocyte Precursor Cells Loss by Inhibiting the Activation of Astrocytes via the SGK1/IL-6 Signalling Pathway. Neurochemical research. 2022-09-13. PMID:36098889. |
in this study, a rat model of hibi was established, and this study measured the changes in il-6 and nod-like receptor thermal protein domain associated protein 3 (nlrp3), in addition to proliferation and apoptosis indicators of oligodendrocyte precursor cells (opcs). |
2022-09-13 |
2023-08-14 |
rat |
| Feng Zhang, Zhixian Gou, Yue Zhou, Lin Huang, Chunyan Shao, Minrong Wang, Chan Wu, Liqun L. MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats. Brain research bulletin. 2022-08-19. PMID:35985609. |
microrna-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats. |
2022-08-19 |
2023-08-14 |
rat |
| Feng Zhang, Zhixian Gou, Yue Zhou, Lin Huang, Chunyan Shao, Minrong Wang, Chan Wu, Liqun L. MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats. Brain research bulletin. 2022-08-19. PMID:35985609. |
excessive oligodendrocyte precursor cell (opc) apoptosis occurs during intrauterine infection-induced white matter injury (wmi) in premature infants, preventing excessive apoptosis of opcs is one of the mechanisms protecting wmi. |
2022-08-19 |
2023-08-14 |
rat |
| Peter G E Kennedy, Woro George, Xiaoli Y. The Possible Role of Neural Cell Apoptosis in Multiple Sclerosis. International journal of molecular sciences. vol 23. issue 14. 2022-07-27. PMID:35886931. |
while oligodendrocyte and neuronal loss in ms may not necessarily be mutually exclusive, particular attention should be given to the role of neuronal apoptosis in the development of axonal loss. |
2022-07-27 |
2023-08-14 |
Not clear |
| Raymond A Sobel, Megan Albertelli, Julian R Hinojoza, Mary Jane Eaton, Kevin V Grimes, Edward Rubenstei. Azetidine-2-Carboxylic Acid-Induced Oligodendrogliopathy: Relevance to the Pathogenesis of Multiple Sclerosis. Journal of neuropathology and experimental neurology. 2022-05-06. PMID:35521963. |
aze induced oligodendrocyte (ol) nucleomegaly and nucleoplasm clearing, dilated endoplasmic reticulum, cytoplasmic vacuolation, abnormal mitochondria, and aze dose-dependent apoptosis. |
2022-05-06 |
2023-08-13 |
mouse |
| Jennifer M Gibson, Tianci Chu, Wenxin Zeng, Ashley C Wethall, Maiying Kong, Nicholas Mellen, Lori A Devlin Phinney, Jun Ca. Perinatal methadone exposure attenuates myelination and induces oligodendrocyte apoptosis in neonatal rat brain. Experimental biology and medicine (Maywood, N.J.). 2022-04-27. PMID:35475383. |
perinatal methadone exposure attenuates myelination and induces oligodendrocyte apoptosis in neonatal rat brain. |
2022-04-27 |
2023-08-13 |
rat |
| Geetha Parthasarathy, Shiva Kumar Goud Gadil. Neuropathogenicity of non-viable Borrelia burgdorferi ex vivo. Scientific reports. vol 12. issue 1. 2022-01-14. PMID:35027599. |
in previous studies, we have shown that non-viable borrelia burgdorferi can induce neuroinflammation and apoptosis in an oligodendrocyte cell line. |
2022-01-14 |
2023-08-13 |
Not clear |
| Xi-Xi Wang, Ling-Ling Cui, Si-Fei Gan, Ze-Ru Zhang, Jing Xiao, Chen-Hong Li, Fang Lu. Inhibition of oligodendrocyte apoptosis in the prelimbic medial prefrontal cortex prevents fentanyl-induced hyperalgesia in rats. The journal of pain. 2022-01-12. PMID:35021116. |
inhibition of oligodendrocyte apoptosis in the prelimbic medial prefrontal cortex prevents fentanyl-induced hyperalgesia in rats. |
2022-01-12 |
2023-08-13 |
rat |
| Xi-Xi Wang, Ling-Ling Cui, Si-Fei Gan, Ze-Ru Zhang, Jing Xiao, Chen-Hong Li, Fang Lu. Inhibition of oligodendrocyte apoptosis in the prelimbic medial prefrontal cortex prevents fentanyl-induced hyperalgesia in rats. The journal of pain. 2022-01-12. PMID:35021116. |
herein we explored the effect of oligodendrocyte apoptosis of pl-mpfc on oih. |
2022-01-12 |
2023-08-13 |
rat |
| Xi-Xi Wang, Ling-Ling Cui, Si-Fei Gan, Ze-Ru Zhang, Jing Xiao, Chen-Hong Li, Fang Lu. Inhibition of oligodendrocyte apoptosis in the prelimbic medial prefrontal cortex prevents fentanyl-induced hyperalgesia in rats. The journal of pain. 2022-01-12. PMID:35021116. |
meanwhile, cleaved-caspase 3 (an apoptosis marker) was increased, whereas the oligodendrocyte precursor cell (opc) marker ng2 remained unchanged. |
2022-01-12 |
2023-08-13 |
rat |
| Xi-Xi Wang, Ling-Ling Cui, Si-Fei Gan, Ze-Ru Zhang, Jing Xiao, Chen-Hong Li, Fang Lu. Inhibition of oligodendrocyte apoptosis in the prelimbic medial prefrontal cortex prevents fentanyl-induced hyperalgesia in rats. The journal of pain. 2022-01-12. PMID:35021116. |
these results suggest that downregulated myelin-related proteins may be associated with oligodendrocyte apoptosis rather than a reduction in their generating source, and immunohistochemistry confirmed this hypothesis. |
2022-01-12 |
2023-08-13 |
rat |
| Xi-Xi Wang, Ling-Ling Cui, Si-Fei Gan, Ze-Ru Zhang, Jing Xiao, Chen-Hong Li, Fang Lu. Inhibition of oligodendrocyte apoptosis in the prelimbic medial prefrontal cortex prevents fentanyl-induced hyperalgesia in rats. The journal of pain. 2022-01-12. PMID:35021116. |
behaviorally, prophylactic blockade of oligodendrocyte apoptosis by microinjection of z-devd-fmk into the pl-mpfc prevented fentanyl-induced mechanical and thermal hyperalgesia, but downregulated myelin basic protein (mbp) gradually recovered in 12 h. we suggest that oih may be primed in part via oligodendrocyte apoptosis in the pl-mpfc. |
2022-01-12 |
2023-08-13 |
rat |
| Xi-Xi Wang, Ling-Ling Cui, Si-Fei Gan, Ze-Ru Zhang, Jing Xiao, Chen-Hong Li, Fang Lu. Inhibition of oligodendrocyte apoptosis in the prelimbic medial prefrontal cortex prevents fentanyl-induced hyperalgesia in rats. The journal of pain. 2022-01-12. PMID:35021116. |
perspective: : in this study we showed that oligodendrocyte apoptosis in the pl-mpfc is a key trigger for fentanyl-induced hyperalgesia. |
2022-01-12 |
2023-08-13 |
rat |
| Xi-Xi Wang, Ling-Ling Cui, Si-Fei Gan, Ze-Ru Zhang, Jing Xiao, Chen-Hong Li, Fang Lu. Inhibition of oligodendrocyte apoptosis in the prelimbic medial prefrontal cortex prevents fentanyl-induced hyperalgesia in rats. The journal of pain. 2022-01-12. PMID:35021116. |
targeting oligodendrocyte apoptosis in the pl-mpfc may prevented hyperalgesia priming induced by fentanyl. |
2022-01-12 |
2023-08-13 |
rat |
| V S B Wies Mancini, A A Di Pietro, S de Olmos, P R Silva, M Vence, M Marder, L M Igaz, M S Marcora, J M Pasquini, J D Correale, L A Pasquin. Colony-stimulating factor-1 receptor inhibition attenuates microgliosis and myelin loss but exacerbates neurodegeneration in the chronic cuprizone model. Journal of neurochemistry. 2021-12-22. PMID:34935149. |
the progressive form of ms can be modelled by the prolonged administration to cuprizone (cpz) in adult mice, as cpz induces highly reproducible demyelination of different brain regions through oligodendrocyte (olg) apoptosis, accompanied by mg and ast activation and axonal damage. |
2021-12-22 |
2023-08-13 |
mouse |
| Abigail H Cleveland, Alejandra Romero-Morales, Laurent Alfonso Azcona, Melisa Herrero, Viktoriya D Nikolova, Sheryl Moy, Orna Elroy-Stein, Vivian Gama, Timothy R Gersho. Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration. Cell death & disease. vol 12. issue 12. 2021-12-07. PMID:34873168. |
we found that brain-wide mcl-1 deletion caused apoptosis specifically in mature oligodendrocytes while sparing astrocytes and oligodendrocyte precursors, resulting in impaired myelination and progressive white matter degeneration. |
2021-12-07 |
2023-08-13 |
mouse |
| Xu Hu, Guanxiu Xiao, Li He, Xiaojie Niu, Huashun Li, Tianjie Lou, Qianqian Hu, Youguang Yang, Qi Xu, Zhengdong Wei, Mengsheng Qiu, Kenji F Tanaka, Ying Shen, Yanmei Ta. Sustained ErbB Activation Causes Demyelination and Hypomyelination by Driving Necroptosis of Mature Oligodendrocytes and Apoptosis of Oligodendrocyte Precursor Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 48. 2021-12-04. PMID:34725188. |
sustained erbb activation causes demyelination and hypomyelination by driving necroptosis of mature oligodendrocytes and apoptosis of oligodendrocyte precursor cells. |
2021-12-04 |
2023-08-13 |
mouse |
| Asier Ruiz, Tania Quintela-López, María V Sánchez-Gómez, Adhara Gaminde-Blasco, Elena Alberdi, Carlos Matut. Mitochondrial division inhibitor 1 disrupts oligodendrocyte Ca Glia. vol 68. issue 9. 2021-11-30. PMID:32060978. |
mitochondrial division inhibitor 1 disrupts oligodendrocyte ca mitochondrial fission mediated by cytosolic dynamin related protein 1 (drp1) is essential for mitochondrial quality control but may contribute to apoptosis as well. |
2021-11-30 |
2023-08-13 |
Not clear |
| Rodrigo G Mira, Matías Lira, Waldo Cerp. Traumatic Brain Injury: Mechanisms of Glial Response. Frontiers in physiology. vol 12. 2021-11-10. PMID:34744783. |
tbi causes oligodendrocyte apoptosis, demyelination, and axonal transport disruption. |
2021-11-10 |
2023-08-13 |
Not clear |