Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Qi Ming Li, Chhavy Tep, Tae Y Yune, Xiao Zhen Zhou, Takafumi Uchida, Kun Ping Lu, Sung Ok Yoo. Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 31. 2007-08-28. PMID:17670986. |
opposite regulation of oligodendrocyte apoptosis by jnk3 and pin1 after spinal cord injury. |
2007-08-28 |
2023-08-12 |
mouse |
Qi Ming Li, Chhavy Tep, Tae Y Yune, Xiao Zhen Zhou, Takafumi Uchida, Kun Ping Lu, Sung Ok Yoo. Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 31. 2007-08-28. PMID:17670986. |
we report that oligodendrocyte apoptosis is regulated oppositely by c-jun n-terminal kinase 3 (jnk3) and protein interacting with the mitotic kinase, never in mitosis a i (pin1), the actions of which converge on myeloid cell leukemia sequence-1 (mcl-1). |
2007-08-28 |
2023-08-12 |
mouse |
Qi Ming Li, Chhavy Tep, Tae Y Yune, Xiao Zhen Zhou, Takafumi Uchida, Kun Ping Lu, Sung Ok Yoo. Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 31. 2007-08-28. PMID:17670986. |
these results are confirmed by the opposing phenotypes observed between jnk3-/- and pin1-/- mice: oligodendrocyte apoptosis and cytochrome c release are reduced in jnk3-/- but elevated in pin1-/- mice. |
2007-08-28 |
2023-08-12 |
mouse |
Ramaswamy Sharma, Alexander Go. Minimal role for caspase 12 in the unfolded protein response in oligodendrocytes in vivo. Journal of neurochemistry. vol 101. issue 4. 2007-07-12. PMID:17394578. |
our investigation in animal models of pmd demonstrates that caspase 12 is activated following accumulation of mutant proteins in oligodendrocytes; however, eliminating caspase 12 activity does not alter pathophysiology with respect to levels of apoptosis, oligodendrocyte function, disease severity or life span. |
2007-07-12 |
2023-08-12 |
Not clear |
R Thomas Zoeller, Rochelle W Tyl, Shirlee W Ta. Current and potential rodent screens and tests for thyroid toxicants. Critical reviews in toxicology. vol 37. issue 1-2. 2007-07-05. PMID:17364705. |
examples of these endpoints under development include computer-assisted morphometry of the brain and evaluation of treatment-related changes in gene expression, thyrotropin-releasing hormone (trh) and tsh challenge tests, and tests to evaluate thyroid hormone (th)-dependent developmental events, especially in the rodent brain (e.g., measures of cerebellar and cortical proliferation, differentiation, migration, apoptosis, planimetric measures and gene expression, and oligodendrocyte differentiation). |
2007-07-05 |
2023-08-12 |
human |
Yin Liu, Xuming Zhan. Murine coronavirus-induced oligodendrocyte apoptosis is mediated through the activation of the Fas signaling pathway. Virology. vol 360. issue 2. 2007-06-07. PMID:17156812. |
murine coronavirus-induced oligodendrocyte apoptosis is mediated through the activation of the fas signaling pathway. |
2007-06-07 |
2023-08-12 |
mouse |
Yin Liu, Xuming Zhan. Murine coronavirus-induced oligodendrocyte apoptosis is mediated through the activation of the Fas signaling pathway. Virology. vol 360. issue 2. 2007-06-07. PMID:17156812. |
these results demonstrate that oligodendrocyte apoptosis is triggered by mhv infection during cell entry through the activation of the fas signaling pathway. |
2007-06-07 |
2023-08-12 |
mouse |
Roumen Balabanov, Krystle Strand, Rajendra Goswami, Eileen McMahon, Wendy Begolka, Stephen D Miller, Brian Popk. Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 8. 2007-03-22. PMID:17314297. |
plp/socs1 mice developed eae with an accelerated onset associated with enhanced early inflammation and markedly increased oligodendrocyte apoptosis. |
2007-03-22 |
2023-08-12 |
mouse |
X-Q Ding, M Goerg, B Eckert, A Ohlenbusch, A Kohlschuetter, J Gaertner, H Zeume. Rapidly progressive vanishing white matter disease in a child with previously inconspicuous brain MRI. Neuropediatrics. vol 37. issue 4. 2007-03-02. PMID:17177153. |
a pathomechanism like tumor necrosis factor induced oligodendrocyte apoptosis and primary demyelination was postulated. |
2007-03-02 |
2023-08-12 |
Not clear |
Yin Liu, Yinghui Pu, Xuming Zhan. Role of the mitochondrial signaling pathway in murine coronavirus-induced oligodendrocyte apoptosis. Journal of virology. vol 80. issue 1. 2007-01-26. PMID:16352564. |
role of the mitochondrial signaling pathway in murine coronavirus-induced oligodendrocyte apoptosis. |
2007-01-26 |
2023-08-12 |
mouse |
Yin Liu, Yinghui Pu, Xuming Zhan. Role of the mitochondrial signaling pathway in murine coronavirus-induced oligodendrocyte apoptosis. Journal of virology. vol 80. issue 1. 2007-01-26. PMID:16352564. |
here we determined the involvement of the mitochondrial pathway in mhv-induced oligodendrocyte apoptosis. |
2007-01-26 |
2023-08-12 |
mouse |
Yin Liu, Yinghui Pu, Xuming Zhan. Role of the mitochondrial signaling pathway in murine coronavirus-induced oligodendrocyte apoptosis. Journal of virology. vol 80. issue 1. 2007-01-26. PMID:16352564. |
these results thus establish the involvement of the mitochondrial pathway in mhv-induced oligodendrocyte apoptosis. |
2007-01-26 |
2023-08-12 |
mouse |
David Liñares, Maaike Taconis, Paula Maña, Manuel Correcha, Sue Fordham, Maria Staykova, David O Willenbor. Neuronal nitric oxide synthase plays a key role in CNS demyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 49. 2006-12-29. PMID:17151270. |
protection was associated with a dramatic increase in mature oligodendrocyte survival and a decrease in apoptosis. |
2006-12-29 |
2023-08-12 |
mouse |
Muriel B Sättler, Iris Demmer, Sarah K Williams, Katharina Maier, Doron Merkler, Ivana Gadjanski, Christine Stadelmann, Mathias Bähr, Ricarda Die. Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16764858. |
we have characterized previously time course and mechanisms of neuronal apoptosis in a rat model of myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis. |
2006-11-14 |
2023-08-12 |
rat |
Michael F Azari, Christos Profyris, Tara Karnezis, Claude C Bernard, David H Small, Surindar S Cheema, Ezgi Ozturk, Irene Hatzinisiriou, Steven Petrato. Leukemia inhibitory factor arrests oligodendrocyte death and demyelination in spinal cord injury. Journal of neuropathology and experimental neurology. vol 65. issue 9. 2006-10-18. PMID:16957585. |
we report that leukemia inhibitory factor (lif) can prevent oligodendrocyte apoptosis, notably contralateral to the spinal cord lesion, through the induction of the jak/stat and akt signaling pathways as well as by potentiating the expression of the antiapoptotic molecule, ciap2. |
2006-10-18 |
2023-08-12 |
Not clear |
Michael F Azari, Christos Profyris, Tara Karnezis, Claude C Bernard, David H Small, Surindar S Cheema, Ezgi Ozturk, Irene Hatzinisiriou, Steven Petrato. Leukemia inhibitory factor arrests oligodendrocyte death and demyelination in spinal cord injury. Journal of neuropathology and experimental neurology. vol 65. issue 9. 2006-10-18. PMID:16957585. |
reduced oligodendrocyte apoptosis after sci with lif administration resulted in a substantial decrease in demyelination shown by the preservation of lamellated myelin surrounding viable axons and deposition of the degraded myelin basic protein. |
2006-10-18 |
2023-08-12 |
Not clear |
Bettina Gerstner, Christoph Bührer, Cornelia Rheinländer, Oliver Polley, Alexandra Schüller, Monika Berns, Michael Obladen, Ursula Felderhoff-Muese. Maturation-dependent oligodendrocyte apoptosis caused by hyperoxia. Journal of neuroscience research. vol 84. issue 2. 2006-09-19. PMID:16673399. |
maturation-dependent oligodendrocyte apoptosis caused by hyperoxia. |
2006-09-19 |
2023-08-12 |
human |
Qiao-Ling Cui, Eli Fogle, Guillermina Almaza. Muscarinic acetylcholine receptors mediate oligodendrocyte progenitor survival through Src-like tyrosine kinases and PI3K/Akt pathways. Neurochemistry international. vol 48. issue 5. 2006-06-01. PMID:16439036. |
here we present evidence that incubation of oligodendrocyte progenitors, deprived of growth factor, with the acetylcholine analog carbachol significantly reduced cell death by apoptosis and blocked caspase-3 cleavage. |
2006-06-01 |
2023-08-12 |
Not clear |
Joris Vanderlocht, Niels Hellings, Jerome J A Hendriks, Frank Vandenabeele, Marjan Moreels, Mieke Buntinx, Dick Hoekstra, Jack P Antel, Piet Stinisse. Leukemia inhibitory factor is produced by myelin-reactive T cells from multiple sclerosis patients and protects against tumor necrosis factor-alpha-induced oligodendrocyte apoptosis. Journal of neuroscience research. vol 83. issue 5. 2006-06-01. PMID:16477612. |
leukemia inhibitory factor is produced by myelin-reactive t cells from multiple sclerosis patients and protects against tumor necrosis factor-alpha-induced oligodendrocyte apoptosis. |
2006-06-01 |
2023-08-12 |
Not clear |
Von R King, Wenlong L Huang, Simon C Dyall, Olimpia E Curran, John V Priestley, Adina T Michael-Titu. Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641248. |
the omega-3 pufas alpha-linolenic acid and docosahexaenoic acid (dha) injected 30 min after injury induced significantly improved locomotor performance and neuroprotection, including decreased lesion size and apoptosis and increased neuronal and oligodendrocyte survival. |
2006-05-23 |
2023-08-12 |
rat |