| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Acs, M A Selak, S Komoly, B Kalma. Distribution of oligodendrocyte loss and mitochondrial toxicity in the cuprizone-induced experimental demyelination model. Journal of neuroimmunology. vol 262. issue 1-2. 2013-11-18. PMID:23890807. |
cuprizone is a copper-chelating mitochondrial toxin that causes oligodendrocyte apoptosis and demyelination preferentially in the corpus callosum (cc) and the superior cerebellar peduncles, but not in the spinal cord (sc) of c57bl/6 mice. |
2013-11-18 |
2023-08-12 |
mouse |
| Jong-Wan Kim, Young J Kim, Young P Chan. Administration of dexamethasone to neonatal rats induces hypomyelination and changes in the morphology of oligodendrocyte precursors. Comparative medicine. vol 63. issue 1. 2013-10-17. PMID:23561937. |
to examine whether hypomyelination in neonatal rats might be related to apoptosis of oligodendrocyte progenitors, we administered dexamethasone (0.5 mg/kg sc) to neonatal rats on postnatal (p) days 1 through 5. |
2013-10-17 |
2023-08-12 |
rat |
| T Bagci-Onder, A Agarwal, D Flusberg, S Wanningen, P Sorger, K Sha. Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors. Oncogene. vol 32. issue 23. 2013-08-05. PMID:22824792. |
tumor necrosis factor related apoptosis-inducing ligand (trail) induces apoptosis specifically in tumor cells and its efficacy has been tested in pre-clinical models by delivering it systemically as a purified ligand or via engineered stem cells (sc). |
2013-08-05 |
2023-08-12 |
mouse |
| Zibo Yang, Baoding Huang, Zhiqi Zhang, Yan Kang, Ming Fu, Weiming Lia. Effects of IL-1 receptor-associated kinase-4 gene silencing on human osteoblast-like cells. Connective tissue research. vol 53. issue 6. 2013-05-03. PMID:22606974. |
compared with the control and sc groups, irak-4 gene silencing in mg63 cells caused morphological changes, inhibited growth, altered the cell-cycle distribution, increased apoptosis (p < 0.05), decreased bone alkaline phosphatase and osteocalcin levels (p < 0.05), and decreased protein expression of bcl-2/bax and bcl-2, p-jnk1/2, p-erk1/2, and p-p38mapk (p < 0.05). |
2013-05-03 |
2023-08-12 |
human |
| Han-Young Kim, Tae Won Choi, Hyun Jung Kim, Sung-Moo Kim, Kyung-Ran Park, Hyeung-Jin Jang, Eun Ha Lee, Chul Young Kim, Sang Hoon Jung, Bum Sang Shim, Kwang Seok Ah. A methylene chloride fraction of Saururus chinensis induces apoptosis through the activation of caspase-3 in prostate and breast cancer cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 18. issue 7. 2012-09-06. PMID:21111586. |
sc also increased the number of annexin v-positive apoptotic bodies and the sub-g1 dna contents of the cell cycle undergoing apoptosis through caspase-3 activation in both lncap and mcf-7 cells. |
2012-09-06 |
2023-08-12 |
human |
| Han-Young Kim, Tae Won Choi, Hyun Jung Kim, Sung-Moo Kim, Kyung-Ran Park, Hyeung-Jin Jang, Eun Ha Lee, Chul Young Kim, Sang Hoon Jung, Bum Sang Shim, Kwang Seok Ah. A methylene chloride fraction of Saururus chinensis induces apoptosis through the activation of caspase-3 in prostate and breast cancer cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 18. issue 7. 2012-09-06. PMID:21111586. |
moreover, we observed that sc potentiated paclitaxel-induced apoptosis in mcf-7 cells and sauchinone is a major active constituent of sc, which could induce apoptosis in the cells. |
2012-09-06 |
2023-08-12 |
human |
| Han-Young Kim, Tae Won Choi, Hyun Jung Kim, Sung-Moo Kim, Kyung-Ran Park, Hyeung-Jin Jang, Eun Ha Lee, Chul Young Kim, Sang Hoon Jung, Bum Sang Shim, Kwang Seok Ah. A methylene chloride fraction of Saururus chinensis induces apoptosis through the activation of caspase-3 in prostate and breast cancer cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 18. issue 7. 2012-09-06. PMID:21111586. |
taken together, our data provide the evidence that sc induces apoptosis depending on caspase-3 activation and overcomes the natural biological resistance to chemotherapy found in human prostate and breast cancer cells. |
2012-09-06 |
2023-08-12 |
human |
| Stephan Heermann, Julia Schmücker, Ursula Hinz, Michael Rickmann, Tilmann Unterbarnscheidt, Markus H Schwab, Kerstin Krieglstei. Neuregulin 1 type III/ErbB signaling is crucial for Schwann cell colonization of sympathetic axons. PloS one. vol 6. issue 12. 2012-08-27. PMID:22194888. |
inhibition of erbb receptor tyrosine kinases leads to reduced sc proliferation, increased apoptosis and thereby severely interfered with sc migration to distal axonal sections and colonization of axons. |
2012-08-27 |
2023-08-12 |
Not clear |
| Anton Gossner, Sofia Roupaka, Jim Foster, Nora Hunter, John Hopkin. Transcriptional profiling of peripheral lymphoid tissue reveals genes and networks linked to SSBP/1 scrapie pathology in sheep. Veterinary microbiology. vol 153. issue 3-4. 2012-05-23. PMID:21684093. |
prp(sc) accumulation of lymphoid tissue resulted in the repression of genes linked to inflammation and oxidative stress, and the up-regulation of genes related to apoptosis. |
2012-05-23 |
2023-08-12 |
Not clear |
| Christopher R R Bjornson, Tom H Cheung, Ling Liu, Pinky V Tripathi, Katherine M Steeper, Thomas A Rand. Notch signaling is necessary to maintain quiescence in adult muscle stem cells. Stem cells (Dayton, Ohio). vol 30. issue 2. 2012-05-22. PMID:22045613. |
sc depletion was not due to apoptosis. |
2012-05-22 |
2023-08-12 |
mouse |
| Lian-Qing Sun, Bing Xue, Xiao-Jin Li, Xuan Wang, Ling Qu, Ting-Ting Zhang, Jue Zhao, Bao-An Wang, Xiao-Man Zou, Yi-Ming Mu, Ju-Ming L. Inhibitory effects of salvianolic acid B on apoptosis of Schwann cells and its mechanism induced by intermittent high glucose. Life sciences. vol 90. issue 3-4. 2012-02-27. PMID:22036624. |
to investigate protective effects of salvianolic acid b (sal b) on the intermittent high glucose (ihg)-induced oxidative stress, mitochondrial pathway activation and schwann cell (sc) apoptosis in vitro. |
2012-02-27 |
2023-08-12 |
Not clear |
| Ronit Elhasid, Sarit Larisc. ARTS-based anticancer therapy: taking aim at cancer stem cells. Future oncology (London, England). vol 7. issue 10. 2012-02-07. PMID:21992730. |
second, after these scs acquire additional transforming mutations and become cancer sc (cscs), they are more likely to survive in the absence of arts owing to increased resistance toward apoptosis. |
2012-02-07 |
2023-08-12 |
mouse |
| L B Lazebnik, E V Golovanova, V A Slupskaia, I E Trubitsina, O V Kniazev, N A Shaposhnikov. [Realities and prospects for the use of cell technologies for the treatment of chronic diffuse liver diseases]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology. issue 6. 2012-01-10. PMID:22168071. |
using the sc with the purpose of treatment in chronic liver diseases is the possibility of disturbed regulation of cell-cell interactions in the liver, the impact on the mechanisms of cell death (necrosis - apoptosis) and fibrogenesis, which makes this method the most relevant and promising in hepatology. |
2012-01-10 |
2023-08-12 |
Not clear |
| Elisabetta Mantuano, Kenneth Henry, Tomonori Yamauchi, Nobuhiko Hiramatsu, Kazuyo Yamauchi, Sumihisa Orita, Kazuhisa Takahashi, Jonathan H Lin, Steven L Gonias, W Marie Campan. The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 38. 2011-12-07. PMID:21940431. |
lrp1 functions as a potent activator of pi3k in scs and, by this mechanism, limits sc apoptosis resulting from increased chop expression in nerve injury. |
2011-12-07 |
2023-08-12 |
rat |
| Amelia Padilla, Magda Descorbeth, Audra L Almeyda, Kimberly Payne, Marino De Leo. Hyperglycemia magnifies Schwann cell dysfunction and cell death triggered by PA-induced lipotoxicity. Brain research. vol 1370. 2011-11-23. PMID:21108938. |
hoescht and annexin v/7aad staining confirmed cell death through apoptosis and the lipotoxic effect was more dramatic in sc cultures grown under high glucose conditions. |
2011-11-23 |
2023-08-12 |
Not clear |
| Guang-Qian Li, Hai-Ping Wang, Chun-Ming Jian. [Effects of edaravone on the expression of GRP78, Caspase-12, and neuron apoptosis in juvenile rat hippocampus after status convulsive]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 49. issue 1. 2011-11-03. PMID:21429313. |
to observe the expression of grp78 (glucose regulated protein, grp78), caspase-12 and the change of neuron apoptosis in the juvenile rat hippocampus after status convulsive (sc), and to explore the effect of edaravone on them. |
2011-11-03 |
2023-08-12 |
rat |
| Yun Lu, Bing-Yuan Zhang, Zhuo-Xia Jia, Wen-Jin Wu, Zheng-Qiao L. Hepatocellular carcinoma HepG2 cell apoptosis and caspase-8 and Bcl-2 expression induced by injectable seed extract of Coix lacryma-jobi. Hepatobiliary & pancreatic diseases international : HBPD INT. vol 10. issue 3. 2011-10-14. PMID:21669575. |
in this study, we assessed apoptosis in the hepatocellular carcinoma (hcc) cell line hepg2 induced by an injectable extract from the seed of coix lacryma-jobi (semen coicis, sc), and monitored the expression of bcl-2 and caspase-8. |
2011-10-14 |
2023-08-12 |
Not clear |
| Hua Li, Xuelian Zhang, Lauren Fishbein, Frederick Kweh, Martha Campbell-Thompson, George Q Perrin, David Muir, Margaret Wallac. Analysis of steroid hormone effects on xenografted human NF1 tumor schwann cells. Cancer biology & therapy. vol 10. issue 8. 2011-06-09. PMID:20699653. |
proliferation and apoptosis by the xenografted sc were examined two months after implantation, by ki67 immunolabeling and tunel. |
2011-06-09 |
2023-08-12 |
mouse |
| Hai-Ping Wang, Xiao-Long Deng, Guang-Qian L. [Effects of edaravone on glial fibrillary acidic protein and interleukin-lβ expression and neuronal apoptosis in juvenile rat hippocampus after status convulsion]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 13. issue 3. 2011-06-09. PMID:21426644. |
to study the effects of edaravone on glial fibrillary acidic protein (gfap) and interleukin-1β (il-lβ) expression and neuronal apoptosis in the juvenile rat hippocampus after status convulsion (sc). |
2011-06-09 |
2023-08-12 |
rat |
| A Celli, D S Mackenzie, D S Crumrine, C L Tu, M Hupe, D D Bikle, P M Elias, T M Maur. Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis. The British journal of dermatology. vol 164. issue 1. 2011-04-27. PMID:20846312. |
in keratinocytes and epidermis, terminal differentiation and barrier repair require physiological apoptosis and differentiation, as evidenced by protein synthesis, caspase 14 expression, lipid secretion and stratum corneum (sc) formation. |
2011-04-27 |
2023-08-12 |
Not clear |