| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nathália L M Lara, Luiz R Franç. Neonatal hypothyroidism does not increase Sertoli cell proliferation in iNOS Reproduction (Cambridge, England). vol 154. issue 1. 2018-03-20. PMID:28420799. |
moreover, we have shown that due to higher sc proliferation and lower germ cell apoptosis, inos deficiency in mice also results in higher testis size and dsp. |
2018-03-20 |
2023-08-13 |
mouse |
| Bing Xue, Lin Wang, Zhe Zhang, Rui Wang, Xin-Xin Xia, Ping-Ping Han, Li-Jun Cao, Yong-Hui Liu, Lian-Qing Su. Puerarin may protect against Schwann cell damage induced by glucose fluctuation. Journal of natural medicines. vol 71. issue 3. 2017-11-30. PMID:28181078. |
the present study focuses on the effects of puerarin on glucose fluctuation-induced oxidative stress-induced schwann cell (sc) apoptosis in vitro. |
2017-11-30 |
2023-08-13 |
Not clear |
| Tadashi Yoshida, Patrice Delafontain. An Intronic Enhancer Element Regulates Angiotensin II Type 2 Receptor Expression during Satellite Cell Differentiation, and Its Activity Is Suppressed in Congestive Heart Failure. The Journal of biological chemistry. vol 291. issue 49. 2017-05-26. PMID:27756842. |
we previously demonstrated that ang ii, via its type 1 receptor, causes muscle protein breakdown and apoptosis and inhibits satellite cell (sc) proliferation and muscle regeneration, likely contributing to cachexia in chf and chronic kidney disease. |
2017-05-26 |
2023-08-13 |
mouse |
| Shuyun Zhang, Baolin Sh. Erythropoietin Modification Enhances the Protection of Mesenchymal Stem Cells on Diabetic Rat-Derived Schwann Cells: Implications for Diabetic Neuropathy. BioMed research international. vol 2017. 2017-04-17. PMID:28299330. |
diabetes-triggered apoptosis of schwann cells (sc) contributes to the degradation of diabetic peripheral neuropathy (dnp). |
2017-04-17 |
2023-08-13 |
rat |
| Shuyun Zhang, Baolin Sh. Erythropoietin Modification Enhances the Protection of Mesenchymal Stem Cells on Diabetic Rat-Derived Schwann Cells: Implications for Diabetic Neuropathy. BioMed research international. vol 2017. 2017-04-17. PMID:28299330. |
erythropoietin (epo) is a potent cytokine capable of reducing apoptosis of sc. |
2017-04-17 |
2023-08-13 |
rat |
| Shuyun Zhang, Baolin Sh. Erythropoietin Modification Enhances the Protection of Mesenchymal Stem Cells on Diabetic Rat-Derived Schwann Cells: Implications for Diabetic Neuropathy. BioMed research international. vol 2017. 2017-04-17. PMID:28299330. |
in normal glucose culture condition, the overexpression of epo in msc promoted the msc-induced restoration of sc from diabetic rats, including increases in gsh level and cell viability, decrease in tunel apoptosis, upregulation of antiapoptotic proteins, p-akt, and bcl-2, and downregulation of proapoptotic proteins, cleaved caspase-3, and bax. |
2017-04-17 |
2023-08-13 |
rat |
| Shuyun Zhang, Baolin Sh. Erythropoietin Modification Enhances the Protection of Mesenchymal Stem Cells on Diabetic Rat-Derived Schwann Cells: Implications for Diabetic Neuropathy. BioMed research international. vol 2017. 2017-04-17. PMID:28299330. |
thus, it could be concluded that epo-msc possessed a potent potential in hampering apoptosis of sc, and the suppression was probably attributed to attenuating oxidative stress and regulating apoptosis related protein factors. |
2017-04-17 |
2023-08-13 |
rat |
| Pattage Madushan Dilhara Jayatissa Fernando, Mei Jing Piao, Susara Ruwan Kumara Madduma Hewage, Hee Kyoung Kang, Eun Sook Yoo, Young Sang Koh, Mi Hee Ko, Chang Sik Ko, Sang Hee Byeon, Seung Ri Mun, Nam Ho Lee, Jin Won Hyu. Photo-protective effect of sargachromenol against UVB radiation-induced damage through modulating cellular antioxidant systems and apoptosis in human keratinocytes. Environmental toxicology and pharmacology. vol 43. 2017-02-09. PMID:26991844. |
furthermore, sc decreased uvb-induced bax, cleaved caspase-9, and cleaved caspase-3 protein levels, but increased that of bcl-2, which are well-known key mediators of apoptosis. |
2017-02-09 |
2023-08-13 |
human |
| Jan P Nicolay, Moritz Felcht, Kai Schledzewski, Sergij Goerdt, Cyrill Gérau. Sézary syndrome: old enigmas, new targets. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. vol 14. issue 3. 2016-12-22. PMID:26972187. |
recently, whole genome and exome sequencing has revealed somatic copy number variations as predominant mutations in sc, primarily affecting apoptosis, nfκb signaling, dna integrity, and t-cell activation. |
2016-12-22 |
2023-08-13 |
Not clear |
| F Marchildon, D Fu, N Lala-Tabbert, N Wiper-Bergero. CCAAT/enhancer binding protein beta protects muscle satellite cells from apoptosis after injury and in cancer cachexia. Cell death & disease. vol 7. 2016-12-13. PMID:26913600. |
further, in cachectic conditional knockout animals lacking c/ebpβ in pax7+ cells, the sc compartment was reduced because of increased apoptosis, and regeneration was impaired. |
2016-12-13 |
2023-08-13 |
Not clear |
| Iram Ahmad, Augusta Fernando, Richard Gurgel, J Jason Clark, Linjing Xu, Marlan R Hanse. Merlin status regulates p75(NTR) expression and apoptotic signaling in Schwann cells following nerve injury. Neurobiology of disease. vol 82. 2016-08-19. PMID:26057084. |
despite elevated levels of p75(ntr), sc apoptosis following axotomy is blunted in p0schΔ39-121 mice relative to wild-type mice suggesting that loss of functional merlin contributes to sc resistance to apoptosis. |
2016-08-19 |
2023-08-13 |
mouse |
| Tomokazu Tanaka, Yoshihiko Kitajima, Shuusuke Miyake, Kazuyoshi Yanagihara, Hiromitsu Hara, Aki Nishijima-Matsunobu, Koichi Baba, Masaaki Shida, Kota Wakiyama, Jun Nakamura, Hirokazu Noshir. The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions. PloS one. vol 10. issue 9. 2016-05-17. PMID:26339797. |
in this study, we revealed that kd cells, but not sc cells, induced apoptosis under conditions of hypoxia (1% o2) due to excessive production of ros. |
2016-05-17 |
2023-08-13 |
Not clear |
| Kah Kooi Ooi, Chien Ing Yeo, Kok-Pian Ang, Abdah Md Akim, Yoke-Kqueen Cheah, Siti Nadiah Abdul Halim, Hoi-Ling Seng, Edward R T Tiekin. Phosphanegold(I) thiolates, Ph3PAu[SC(OR)=NC 6H 4Me-4] for R = Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nuclear factor-κB activation pathway and ubiquitination. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. vol 20. issue 5. 2016-04-05. PMID:26003312. |
phosphanegold(i) thiolates, ph3pau[sc(or)=nc 6h 4me-4] for r = me, et and ipr, induce apoptosis, cell cycle arrest and inhibit cell invasion of ht-29 colon cancer cells through modulation of the nuclear factor-κb activation pathway and ubiquitination. |
2016-04-05 |
2023-08-13 |
human |
| Zheqiong Yang, Anamaria Balic, Frederic Michon, Emma Juuri, Irma Theslef. Mesenchymal Wnt/β-Catenin Signaling Controls Epithelial Stem Cell Homeostasis in Teeth by Inhibiting the Antiapoptotic Effect of Fgf10. Stem cells (Dayton, Ohio). vol 33. issue 5. 2016-03-28. PMID:25693510. |
we conclude that the homeostasis of the epithelial sc population in the mouse incisor depends on a proper rate of apoptosis and that this apoptosis is controlled by signals from the mesenchyme surrounding the lacl. |
2016-03-28 |
2023-08-13 |
mouse |
| Chun-qi Gao, Yin-ling Zhao, Hai-chang Li, Wei-guo Sui, Hui-chao Yan, Xiu-qi Wan. Heat stress inhibits proliferation, promotes growth, and induces apoptosis in cultured Lantang swine skeletal muscle satellite cells. Journal of Zhejiang University. Science. B. vol 16. issue 6. 2016-03-04. PMID:26055917. |
heat shock protein 70 (hsp70) expression and sc size are significantly increased (p<0.05) by hs, but cell proliferation is suppressed (p<0.05) and apoptosis is induced (p<0.05). |
2016-03-04 |
2023-08-13 |
Not clear |
| S Sekaran, P Balaganapathy, R Parsanathan, S Elangovan, J Gunashekar, F A Bhat, A Jagadeesa. Lactational exposure of phthalate causes long-term disruption in testicular architecture by altering tight junctional and apoptotic protein expression in Sertoli cells of first filial generation pubertal Wistar rats. Human & experimental toxicology. vol 34. issue 6. 2016-03-02. PMID:25352649. |
dehp-treated rats also showed increased oxidative stress by decreasing antioxidant levels in the scs; it disrupted sc tight junctional proteins occludin, claudin, junctional adhesion molecule, zona occludens protein-1 (zo-1), zona occludens protein-2 (zo-2), and afadin-6 (af-6), increased apoptosis by altering the apoptotic genes bax, cytochrome c, caspase-8, -9, -3 and antiapoptotic gene bcl-2. |
2016-03-02 |
2023-08-13 |
rat |
| M Li, P Zhang, H Li, Y Zhu, S Cui, D Ya. TGF-β1 is critical for Wallerian degeneration after rat sciatic nerve injury. Neuroscience. vol 284. 2015-12-30. PMID:25451291. |
knock down of tgf-β1 expressions resulted in the reduction of sc proliferation and apoptosis, up regulation of cytokines and smad2, 4. |
2015-12-30 |
2023-08-13 |
rat |
| M Li, P Zhang, H Li, Y Zhu, S Cui, D Ya. TGF-β1 is critical for Wallerian degeneration after rat sciatic nerve injury. Neuroscience. vol 284. 2015-12-30. PMID:25451291. |
enhanced expression of tgf-β1 could promote sc proliferation and apoptosis, down regulation of cytokines and smad2, 4. |
2015-12-30 |
2023-08-13 |
rat |
| Lin Wang, Chang Fei, Zheng-Lan Huang, Hui Li, Zhang-Lin Liu, Wen-Li Fen. [Effect of Recombinant Adenovirus AdE-SH2-Caspase 8 on the Apoptosis of Imatinib-resistant K562/G01 Cell Line]. Zhongguo shi yan xue ye xue za zhi. vol 23. issue 4. 2015-11-23. PMID:26314429. |
to investigate the effect of sh2-caspase 8 fusion protein expressed by recombinant adenovirus ade-sh2-caspase8-ha-gfp (sc) on the apoptosis of k562/g01 cell line, which is a bcr/abl positive chronic myeloid leukemia cell line and resistant to imatinib. |
2015-11-23 |
2023-08-13 |
Not clear |
| Heather Brockway, Nathan Balukoff, Martha Dean, Benjamin Alleva, Sarit Smolikov. The CSN/COP9 signalosome regulates synaptonemal complex assembly during meiotic prophase I of Caenorhabditis elegans. PLoS genetics. vol 10. issue 11. 2015-11-10. PMID:25375142. |
we also find a marked increase in apoptosis in csn mutants that specifically eliminates nuclei with aggregated sc proteins. |
2015-11-10 |
2023-08-13 |
caenorhabditis_elegans |