| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mark Kristiansen, Marcus J Messenger, Peter-Christian Klöhn, Sebastian Brandner, Jonathan D F Wadsworth, John Collinge, Sarah J Tabriz. Disease-related prion protein forms aggresomes in neuronal cells leading to caspase activation and apoptosis. The Journal of biological chemistry. vol 280. issue 46. 2006-01-10. PMID:16157591. |
prp(sc) aggresome formation was directly associated with activation of caspase 3 and 8, resulting in apoptosis. |
2006-01-10 |
2023-08-12 |
mouse |
| Rosane B Oliveira, Elizabeth P Sampaio, Fernando Aarestrup, Rosane M B Teles, Tatiana P Silva, Ariane L Oliveira, Paulo R Z Antas, Euzenir N Sarn. Cytokines and Mycobacterium leprae induce apoptosis in human Schwann cells. Journal of neuropathology and experimental neurology. vol 64. issue 10. 2005-11-03. PMID:16215460. |
tnfalpha/tgfbeta combination as well as m. leprae infection triggered an increase in the apoptosis rate in the cultured sc. |
2005-11-03 |
2023-08-12 |
human |
| Roni Engelstein, Nikolas Grigoriadis, Nigel H Greig, Haim Ovadia, Ruth Gabizo. Inhibition of P53-related apoptosis had no effect on PrP(Sc) accumulation and prion disease incubation time. Neurobiology of disease. vol 18. issue 2. 2005-05-12. PMID:15686956. |
inhibition of p53-related apoptosis had no effect on prp(sc) accumulation and prion disease incubation time. |
2005-05-12 |
2023-08-12 |
Not clear |
| M Profita, R Gagliardo, R Di Giorgi, A Bruno, L Riccobono, A Bonanno, J Bousquet, A M Vignol. In vitro effects of flunisolide on MMP-9, TIMP-1, fibronectin, TGF-beta1 release and apoptosis in sputum cells freshly isolated from mild to moderate asthmatics. Allergy. vol 59. issue 9. 2005-02-10. PMID:15291899. |
we evaluated the ability of flunisolide to inhibit in vitro the release of metalloproteinases-9 (mmp-9), tissue inhibitor metalloproteinases-1 (timp-1), transforming growth factor (tgf-beta) and fibronectin by sputum cells (sc) as well as to induce sputum eosinophil apoptosis. |
2005-02-10 |
2023-08-12 |
Not clear |
| Joaquin Castilla, Claudio Hetz, Claudio Sot. Molecular mechanisms of neurotoxicity of pathological prion protein. Current molecular medicine. vol 4. issue 4. 2004-11-24. PMID:15354870. |
transmissible spongiform encephalopathies or prion related disorders are fatal and infectious neurodegenerative diseases characterized by extensive neuronal apoptosis and accumulation of a misfolded form of the cellular prion protein (prp), denoted prp(sc). |
2004-11-24 |
2023-08-12 |
Not clear |
| Joaquin Castilla, Claudio Hetz, Claudio Sot. Molecular mechanisms of neurotoxicity of pathological prion protein. Current molecular medicine. vol 4. issue 4. 2004-11-24. PMID:15354870. |
although the mechanism of neurodegeneration and the involvement of prp(sc) is far from clear, data indicates that neuronal apoptosis might be related to activation of several signaling pathways, including proteasome dysfunction, alterations in prion maturation pathway and endoplasmic reticulum (er) stress. |
2004-11-24 |
2023-08-12 |
Not clear |
| Robert R Myers, Yasufumi Sekiguchi, Shinichi Kikuchi, Brian Scott, Satya Medicherla, Andrew Protter, W Marie Campan. Inhibition of p38 MAP kinase activity enhances axonal regeneration. Experimental neurology. vol 184. issue 2. 2004-04-02. PMID:14769353. |
tnf dose-dependently induces schwann cell and macrophage activation in vivo and apoptosis in primary sc cultures in vitro, while inhibition of p38 mapk is thought to block these cellular processes. |
2004-04-02 |
2023-08-12 |
Not clear |
| Yuk Yin Ng, Berris van Kessel, Henk M Lokhorst, Miranda R M Baert, Caroline M M van den Burg, Andries C Bloem, Frank J T Staa. Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity. Journal of leukocyte biology. vol 75. issue 2. 2004-03-26. PMID:14634063. |
these genes are involved in proliferation, differentiation, apoptosis, and engraftment capacity of sc. |
2004-03-26 |
2023-08-12 |
human |
| Kathleen M Ogilvie, Régis Saladin, Tim R Nagy, Mary S Urcan, Richard A Heyman, Mark D Leibowit. Activation of the retinoid X receptor suppresses appetite in the rat. Endocrinology. vol 145. issue 2. 2004-02-24. PMID:14605005. |
in parallel with those changes in energy balance, we show here that activation of rxr pathways results in adipose tissue remodeling, particularly within sc fat where the rate of apoptosis is increased 5-fold. |
2004-02-24 |
2023-08-12 |
rat |
| Claudio Hetz, Milene Russelakis-Carneiro, Kinsey Maundrell, Joaquin Castilla, Claudio Sot. Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. The EMBO journal. vol 22. issue 20. 2004-01-09. PMID:14532116. |
prion diseases are characterized by accumulation of misfolded prion protein (prp(sc)), and neuronal death by apoptosis. |
2004-01-09 |
2023-08-12 |
mouse |
| Claudio Hetz, Milene Russelakis-Carneiro, Kinsey Maundrell, Joaquin Castilla, Claudio Sot. Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. The EMBO journal. vol 22. issue 20. 2004-01-09. PMID:14532116. |
here we show that nanomolar concentrations of purified prp(sc) from mouse scrapie brain induce apoptosis of n2a neuroblastoma cells. |
2004-01-09 |
2023-08-12 |
mouse |
| Bruno Bonetti, Paola Valdo, Giovanni Ossi, Luca De Toni, Barbara Masotto, Silvia Marconi, Nicolò Rizzuto, Ettore Nardelli, Giuseppe Morett. T-cell cytotoxicity of human Schwann cells: TNFalpha promotes fasL-mediated apoptosis and IFN gamma perforin-mediated lysis. Glia. vol 43. issue 2. 2003-11-18. PMID:12838506. |
inactivation of fasl with the neutralizing antibody nok-2 abolished t-cell apoptosis induced by sc treated with tnfalpha, but not by sc treated with ifn gamma. |
2003-11-18 |
2023-08-12 |
human |
| A V Baskov, A G Korshunov, I A Borshchenko, F S Satanov. [Immunohistochemical study of apoptosis in the cells of experimental injured spinal cord]. Arkhiv patologii. vol 64. issue 2. 2002-08-09. PMID:12107898. |
we studied the temporal and spatial profile of apoptosis following acute spinal cord (sc) injury in rats and influence of chicken yolk transplantation on the programmed cell death. |
2002-08-09 |
2023-08-12 |
rat |
| A V Baskov, A G Korshunov, I A Borshchenko, F S Satanov. [Immunohistochemical study of apoptosis in the cells of experimental injured spinal cord]. Arkhiv patologii. vol 64. issue 2. 2002-08-09. PMID:12107898. |
temporal and spatial course of apoptosis was estimated in longitudinal sections of the sc by tunel assay technique 4 hours, 3 days, 2 weeks, 40 days and 3 months after the injury. |
2002-08-09 |
2023-08-12 |
rat |
| M T Abreu, E T Arnold, J Y Chow, K E Barret. Phosphatidylinositol 3-kinase-dependent pathways oppose Fas-induced apoptosis and limit chloride secretion in human intestinal epithelial cells. Implications for inflammatory diarrheal states. The Journal of biological chemistry. vol 276. issue 50. 2002-01-24. PMID:11551934. |
apoptosis, barrier function, changes in short circuit current (deltai(sc)), and expression of adhesion molecules were assessed. |
2002-01-24 |
2023-08-12 |
human |
| H L Cheng, M Steinway, C L Delaney, T F Franke, E L Feldma. IGF-I promotes Schwann cell motility and survival via activation of Akt. Molecular and cellular endocrinology. vol 170. issue 1-2. 2001-08-23. PMID:11162904. |
we previously reported insulin-like growth factor-i (igf-i) promotes schwann cell (sc) motility and rescues sc from apoptosis induced by serum deprivation. |
2001-08-23 |
2023-08-12 |
Not clear |
| H L Cheng, M Steinway, C L Delaney, T F Franke, E L Feldma. IGF-I promotes Schwann cell motility and survival via activation of Akt. Molecular and cellular endocrinology. vol 170. issue 1-2. 2001-08-23. PMID:11162904. |
in the current study, we examined the role of akt, a downstream kinase of pi-3k, in sc motility and igf-i mediated protection from apoptosis. |
2001-08-23 |
2023-08-12 |
Not clear |
| A Weishaupt, W Brück, T Hartung, K V Toyka, R Gol. Schwann cell apoptosis in experimental autoimmune neuritis of the Lewis rat and the functional role of tumor necrosis factor-alpha. Neuroscience letters. vol 306. issue 1-2. 2001-08-16. PMID:11403962. |
schwann cell (sc) apoptosis may be a critical factor challenging nerve remyelination and regeneration in experimental autoimmune neuritis (ean) in the lewis rat. |
2001-08-16 |
2023-08-12 |
rat |
| A Weishaupt, W Brück, T Hartung, K V Toyka, R Gol. Schwann cell apoptosis in experimental autoimmune neuritis of the Lewis rat and the functional role of tumor necrosis factor-alpha. Neuroscience letters. vol 306. issue 1-2. 2001-08-16. PMID:11403962. |
antigen specific therapy had no clear effect on sc apoptosis. |
2001-08-16 |
2023-08-12 |
rat |
| A Weishaupt, W Brück, T Hartung, K V Toyka, R Gol. Schwann cell apoptosis in experimental autoimmune neuritis of the Lewis rat and the functional role of tumor necrosis factor-alpha. Neuroscience letters. vol 306. issue 1-2. 2001-08-16. PMID:11403962. |
the effects on sc apoptosis were determined by morphological criteria or by in situ tailing (ist) followed by immunocytochemical analysis. |
2001-08-16 |
2023-08-12 |
rat |