| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicole Oatman, Mruniya V Gawali, Sunny Congrove, Roman Caceres, Abitha Sukumaran, Nishtha Gupta, Narmadha Murugesan, Priyanka Arora, Sri Vidhya Subramanian, Kwangmin Choi, Zalfa Abdel-Malek, Julie A Reisz, Daniel Stephenson, Ravi Amaravadi, Pankaj Desai, Angelo D'Alessandro, Kakajan Komurov, Biplab Dasgupt. A multimodal drug-diet-immunotherapy combination restrains melanoma progression and metastasis. Cancer research. 2024-06-17. PMID:38885087. |
the combination reduced monounsaturated fatty acids and increased saturated fatty acids, inducing robust apoptosis and growth suppression and inhibiting lung metastasis with minimal toxicity in preclinical mouse models of pten wildtype melanoma. |
2024-06-17 |
2024-06-21 |
mouse |
| Peng Sun, Kang Huo, Fude Liu, Yawen Cheng, Chen Chen, Jianfeng Han, Jia Y. Regulation and molecular mechanism of adiponectin on the proliferation, apoptosis, autophagy, and chemosensitivity of LN18 Glioma cell line. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 6. 2024-06-05. PMID:38836664. |
moreover, adiponectin inhibits the proliferation rate of the pten wild-type glioma cell line ln18, enhances the expression of cleaved caspase3 and bax, and significantly elevates the apoptosis rate, as evidenced by annexinv/pi flow cytometry. |
2024-06-05 |
2024-06-07 |
Not clear |
| Fatemeh Sadat Hosseini, Abdolreza Ahmadi, Prashant Kesharwani, Hossein Hosseini, Amirhossein Sahebka. Regulatory effects of statins on Akt signaling for prevention of cancers. Cellular signalling. vol 120. 2024-05-11. PMID:38729324. |
akt signaling plays a crucial role in key cancer cell features like proliferation, invasion, and apoptosis by activating multiple effectors in downstream pathways such as foxo, pten, nf-κb, gsk3β, and mtor. |
2024-05-11 |
2024-05-27 |
Not clear |
| Guoxin Liang, Chang Guo, Hongyue Tang, Mingming Zhan. miR-30a-5p attenuates hypoxia/reoxygenation-induced cardiomyocyte apoptosis by regulating PTEN protein expression and activating PI3K/Akt signaling pathway. BMC cardiovascular disorders. vol 24. issue 1. 2024-05-05. PMID:38705985. |
mir-30a-5p attenuates hypoxia/reoxygenation-induced cardiomyocyte apoptosis by regulating pten protein expression and activating pi3k/akt signaling pathway. |
2024-05-05 |
2024-05-08 |
Not clear |
| Pan Zhou, Xingwen Meng, Zhimin Nie, Hua Wang, Kaijun Wang, Aihua Du, Yu Le. PTEN: an emerging target in rheumatoid arthritis? Cell communication and signaling : CCS. vol 22. issue 1. 2024-04-27. PMID:38671436. |
phosphatase and tensin homolog deleted on chromosome 10 (pten) is a critical tumor suppressor protein that regulates various biological processes such as cell proliferation, apoptosis, and inflammatory responses by controlling the phosphatidylinositol 3-kinase (pi3k)/protein kinase b (pi3k/akt) signaling pathway. |
2024-04-27 |
2024-04-29 |
Not clear |
| Lin Ding, Ruo-Yu Wang, Fan Zhang, Meng-Si Wu, Bin Chen, Ke-Wei Su. [Bupleuri Radix-Paeoniae Radix Alba medicated plasma exerts effects on HepG2 hepatoma cells by regulating miR-1297/PTEN signaling axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 4. 2024-04-15. PMID:38621914. |
in conclusion, bupleuri radix-paeoniae radix alba medicated plasma can inhibit the expression of mir-1297 in hepg2 hepatoma cells, promote the expression of pten, and negatively regulate pi3k/akt signaling pathway, thereby inhibiting the proliferation and inducing the apoptosis of hepg2 cells. |
2024-04-15 |
2024-04-18 |
Not clear |
| Jia-Yuan Zhang, Szu-Kai Fu, Hsia-Ling Tai, Kuo-Wei Tseng, Chia-Yu Tang, Chia-Hsien Yu, Chang-Chi La. A Comparative Study: Cardioprotective Effects of High-Intensity Interval Training Versus Ischaemic Preconditioning in Rat Myocardial Ischaemia-Reperfusion. Life (Basel, Switzerland). vol 14. issue 3. 2024-03-28. PMID:38541636. |
furthermore, the expression of pro-apoptotic proteins pten, caspase-3, tnf-α, and bax in the myocardium was reduced, and the expression of anti-apoptotic b-cell lymphoma 2 (bcl-2) was increased, ultimately reducing cellular apoptosis in the myocardium. |
2024-03-28 |
2024-03-30 |
rat |
| Fang Fang, Xiaoyan Zhang, Yun Fan. Diosgenin inhibits proliferation and migration of ovarian cancer cells and induce apoptosis via upregulation of PTEN. Chemical biology & drug design. vol 103. issue 3. 2024-03-27. PMID:38538058. |
diosgenin inhibits proliferation and migration of ovarian cancer cells and induce apoptosis via upregulation of pten. |
2024-03-27 |
2024-03-30 |
Not clear |
| Kai Zhu, Yan Zhang, DongDong Li, MingZhong Xie, HuaCai Jiang, KaiQuan Zhang, Yang Lei, GuangYou Che. MiR-29a-3p mediates phosphatase and tensin homolog and inhibits osteoarthritis progression. Functional & integrative genomics. vol 24. issue 2. 2024-03-12. PMID:38467932. |
mir-29a-3p can stimulate chondrocyte proliferation and inhibit apoptosis by inhibiting pten expression. |
2024-03-12 |
2024-03-14 |
human |
| Qianfei Wang, Yiming Huang, Zherui F. Bone mesenchymal stem cell-derived exosomal miR-26a-3p promotes autophagy to attenuate LPS-induced apoptosis and inflammation in pulmonary microvascular endothelial cells. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 2. 2024-03-02. PMID:38430034. |
mir-26a-3p overexpression reduced cell apoptosis, and inflammation and promoted autophagy by silencing pten. |
2024-03-02 |
2024-03-04 |
rat |
| . RETRACTION: Circular RNA-ZFR Inhibited Cell Proliferation and Promoted Apoptosis in Gastric Cancer by Sponging miR-130a/miR-107 and Modulating PTEN. Cancer research and treatment. 2024-02-21. PMID:38379395. |
retraction: circular rna-zfr inhibited cell proliferation and promoted apoptosis in gastric cancer by sponging mir-130a/mir-107 and modulating pten. |
2024-02-21 |
2024-02-23 |
Not clear |
| Shaohui Li, Yunwei Wang, Yang Chen, Hao Zhang, Peng Cao, Kuo Shen, Hao Gua. PTEN hinders the formation of scars by regulating the levels of proteins in the extracellular matrix and promoting the apoptosis of dermal fibroblasts through Bcl-xL. Archives of biochemistry and biophysics. 2024-02-07. PMID:38325773. |
pten hinders the formation of scars by regulating the levels of proteins in the extracellular matrix and promoting the apoptosis of dermal fibroblasts through bcl-xl. |
2024-02-07 |
2024-02-10 |
Not clear |
| Shaohui Li, Yunwei Wang, Yang Chen, Hao Zhang, Peng Cao, Kuo Shen, Hao Gua. PTEN hinders the formation of scars by regulating the levels of proteins in the extracellular matrix and promoting the apoptosis of dermal fibroblasts through Bcl-xL. Archives of biochemistry and biophysics. 2024-02-07. PMID:38325773. |
the processes of cell proliferation and apoptosis are notably influenced by pten. |
2024-02-07 |
2024-02-10 |
Not clear |
| Shaohui Li, Yunwei Wang, Yang Chen, Hao Zhang, Peng Cao, Kuo Shen, Hao Gua. PTEN hinders the formation of scars by regulating the levels of proteins in the extracellular matrix and promoting the apoptosis of dermal fibroblasts through Bcl-xL. Archives of biochemistry and biophysics. 2024-02-07. PMID:38325773. |
the findings of our study provide validation for the role of pten in inhibiting the development of hypertrophic scars (hs) by modulating the expression of extracellular matrix (ecm) proteins and promoting apoptosis in hypertrophic scar fibroblasts (hsfs) via bcl-xl. |
2024-02-07 |
2024-02-10 |
Not clear |
| Emergency Medicine Internationa. Retracted: Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch. Emergency medicine international. vol 2024. 2024-02-01. PMID:38298978. |
retracted: effect of mir-144-3p-targeted regulation of pten on proliferation, apoptosis, and osteogenic differentiation of bone marrow mesenchymal stem cells under stretch. |
2024-02-01 |
2024-02-03 |
Not clear |
| Retraction: MiR-25-3p targets PTEN to regulate the migration, invasion, and apoptosis of esophageal cancer cells via the PI3K/AKT pathway. Bioscience reports. vol 44. issue 1. 2024-01-31. PMID:38293726. |
retraction: mir-25-3p targets pten to regulate the migration, invasion, and apoptosis of esophageal cancer cells via the pi3k/akt pathway. |
2024-01-31 |
2024-02-02 |
Not clear |
| Yanyang Cai, Haibin Yan, Fang Wang, Lufan Xi. Knocking down of lncRNA SBF2-AS1 inhibits proliferation, invasion and induces apoptosis of colorectal cancer through regulating PTEN. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 14. 2024-01-27. PMID:38279439. |
knocking down of lncrna sbf2-as1 inhibits proliferation, invasion and induces apoptosis of colorectal cancer through regulating pten. |
2024-01-27 |
2024-01-29 |
Not clear |
| Yanyang Cai, Haibin Yan, Fang Wang, Lufan Xi. Knocking down of lncRNA SBF2-AS1 inhibits proliferation, invasion and induces apoptosis of colorectal cancer through regulating PTEN. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 14. 2024-01-27. PMID:38279439. |
knocking down of lncrna sbf2-as1 inhibits proliferation, and invasion and induces apoptosis of colorectal cancer by interacting with ezh2 to downregulate pten level. |
2024-01-27 |
2024-01-29 |
Not clear |
| Huahua Su, Yan Lv, Lixian Zhu, Yanhua Wan. Roles of PTEN gene methylation in Se-CQDs induced mitochondrial apoptosis of osteosarcoma cells. Colloids and surfaces. B, Biointerfaces. vol 234. 2024-01-19. PMID:38241895. |
roles of pten gene methylation in se-cqds induced mitochondrial apoptosis of osteosarcoma cells. |
2024-01-19 |
2024-01-22 |
Not clear |
| Liqing Lu, Dejun Ma, Zhen X. Coexpression of TP53, BIM, and PTEN Enhances the Therapeutic Efficacy of Non-Small-Cell Lung Cancer. Biomacromolecules. 2024-01-18. PMID:38237562. |
in cell transfection tests, np-tp53-bim-pten could coexpress tp53, bim, and pten in nci-h1299 cells and induce cell apoptosis with a ratio of up to 94.9%. |
2024-01-18 |
2024-01-21 |
mouse |