| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lin Li, Huan-Huan Wang, Xin-Tian Nie, Wan-Ru Jiang, Yuan-Shu Zhan. Sodium butyrate ameliorates lipopolysaccharide-induced cow mammary epithelial cells from oxidative stress damage and apoptosis. Journal of cellular biochemistry. 2019-11-20. PMID:30259565. |
in addition, nab decreased apoptosis by inhibiting caspase-3, caspase-9, and bax protein levels, and this action was mainly achieved via activation of the pi3k/akt signaling pathways in lps-induced mac-t cells. |
2019-11-20 |
2023-08-13 |
Not clear |
| Matthew A Taylor, Firas Khathayer, Swapan K Ra. Quercetin and Sodium Butyrate Synergistically Increase Apoptosis in Rat C6 and Human T98G Glioblastoma Cells Through Inhibition of Autophagy. Neurochemical research. vol 44. issue 7. 2019-08-12. PMID:31011879. |
this study investigated the efficacy of quercetin (qct) in combination with sodium butyrate (nab) in enhancing apoptosis in rat c6 and human t98g glioblastoma cells though blockage of autophagy under nutrient-starvation. |
2019-08-12 |
2023-08-13 |
human |
| Matthew A Taylor, Firas Khathayer, Swapan K Ra. Quercetin and Sodium Butyrate Synergistically Increase Apoptosis in Rat C6 and Human T98G Glioblastoma Cells Through Inhibition of Autophagy. Neurochemical research. vol 44. issue 7. 2019-08-12. PMID:31011879. |
western blotting results showed that combination of qct and nab increased apoptosis by decreasing anti-apoptotic bcl-2 and increasing pro-apoptotic bax, decreasing survivin, activating caspase-3, and degrading poly (adp-ribose) polymerase (parp). |
2019-08-12 |
2023-08-13 |
human |
| Yimeng Hu, Jie Liu, Yin Yuan, Jing Chen, Siyuan Cheng, Huawei Wang, Yancheng X. Sodium butyrate mitigates type 2 diabetes by inhibiting PERK-CHOP pathway of endoplasmic reticulum stress. Environmental toxicology and pharmacology. vol 64. 2019-01-28. PMID:30342372. |
our objective was to explore the effect and underlying mechanism of nab on islet β-cell dysfunction and apoptosis in type 2 diabetic (t2dm) rats. |
2019-01-28 |
2023-08-13 |
rat |
| Yimeng Hu, Jie Liu, Yin Yuan, Jing Chen, Siyuan Cheng, Huawei Wang, Yancheng X. Sodium butyrate mitigates type 2 diabetes by inhibiting PERK-CHOP pathway of endoplasmic reticulum stress. Environmental toxicology and pharmacology. vol 64. 2019-01-28. PMID:30342372. |
nab also improved diabetes-induced histological alteration of islet and functional damage; moreover, results of tunel and western blotting indicated nab alleviated β-cell apoptosis. |
2019-01-28 |
2023-08-13 |
rat |
| Betul Yilmaz, Arzu Zeynep Karaba. Food Additive Sodium Benzoate (NaB) Activates NFκB and Induces Apoptosis in HCT116 Cells. Molecules (Basel, Switzerland). vol 23. issue 4. 2018-09-04. PMID:29565269. |
food additive sodium benzoate (nab) activates nfκb and induces apoptosis in hct116 cells. |
2018-09-04 |
2023-08-13 |
Not clear |
| Betul Yilmaz, Arzu Zeynep Karaba. Food Additive Sodium Benzoate (NaB) Activates NFκB and Induces Apoptosis in HCT116 Cells. Molecules (Basel, Switzerland). vol 23. issue 4. 2018-09-04. PMID:29565269. |
in this study, the effects of nab on viability parameters and nfκb, one of the most important regulators in apoptosis, were examined in hct116 colon cancer cells. |
2018-09-04 |
2023-08-13 |
Not clear |
| Betul Yilmaz, Arzu Zeynep Karaba. Food Additive Sodium Benzoate (NaB) Activates NFκB and Induces Apoptosis in HCT116 Cells. Molecules (Basel, Switzerland). vol 23. issue 4. 2018-09-04. PMID:29565269. |
nab (6.25 mm-50 mm) treatment inhibited cell viability by inducing apoptosis, which was evident with increased annexin v-pe staining and caspase-3 activity. |
2018-09-04 |
2023-08-13 |
Not clear |
| Betul Yilmaz, Arzu Zeynep Karaba. Food Additive Sodium Benzoate (NaB) Activates NFκB and Induces Apoptosis in HCT116 Cells. Molecules (Basel, Switzerland). vol 23. issue 4. 2018-09-04. PMID:29565269. |
nfκb activation accompanied the induction of apoptosis in nab treated cells. |
2018-09-04 |
2023-08-13 |
Not clear |
| Betul Yilmaz, Arzu Zeynep Karaba. Food Additive Sodium Benzoate (NaB) Activates NFκB and Induces Apoptosis in HCT116 Cells. Molecules (Basel, Switzerland). vol 23. issue 4. 2018-09-04. PMID:29565269. |
overall, these results suggest that nab induces apoptosis and activates nfκb in hct116 colon cancer cells. |
2018-09-04 |
2023-08-13 |
Not clear |
| Andrew J Tsung, Maheedhara R Guda, Swapna Asuthkar, Collin M Labak, Ian J Purvis, Yining Lu, Neha Jain, Sarah E Bach, Durbaka V R Prasad, Kiran K Velpul. Methylation regulates HEY1 expression in glioblastoma. Oncotarget. vol 8. issue 27. 2018-04-06. PMID:28574840. |
nab treatment also induced apoptosis of gbm cells as measured by flow cytometric analysis. |
2018-04-06 |
2023-08-13 |
Not clear |
| Ying Wang, Peng-Chao Hu, Yan-Bin Ma, Rong Fan, Fang-Fang Gao, Jing-Wei Zhang, Lei We. Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. Ultrastructural pathology. vol 40. issue 4. 2017-03-27. PMID:27158913. |
here, we demonstrated that a certain concentration of nab effectively induced mcf-7 cell apoptosis. |
2017-03-27 |
2023-08-13 |
Not clear |
| Zhao-Tong Wang, Zhuo-Jia Chen, Guan-Min Jiang, Ying-Min Wu, Tao Liu, Yan-Mei Yi, Jun Zeng, Jun Du, Hong-Sheng Wan. Histone deacetylase inhibitors suppress mutant p53 transcription via HDAC8/YY1 signals in triple negative breast cancer cells. Cellular signalling. vol 28. issue 5. 2016-12-13. PMID:26876786. |
our present study reveals that histone deacetylase inhibitors (hdacis) suberoyl anilide hydroxamic acid (saha) and sodium butyrate (nab) significantly inhibit cell proliferation, arrest cell cycle at g0/g1 phase, and induce mitochondrial related apoptosis of tnbc cells. |
2016-12-13 |
2023-08-13 |
human |
| Peng Zhang, James C Weaver, Gang Chen, Julia Beretov, Tatsuya Atsumi, Miao Qi, Ravinay Bhindi, Jian C Qi, Michele C Madigan, Bill Giannakopoulos, Steven A Krili. The Fifth Domain of Beta 2 Glycoprotein I Protects from Natural IgM Mediated Cardiac Ischaemia Reperfusion Injury. PloS one. vol 11. issue 3. 2016-08-05. PMID:27031114. |
domain v treatment in wt mice also resulted in less neutrophil infiltration, less apoptosis and improved ejection fraction at 24 h. rag-1 -/- antibody deficient mice reconstituted with igm nabs confirmed that domain v prevented igm nab induced cardiac iri. |
2016-08-05 |
2023-08-13 |
mouse |
| Ebrahim Eftekhar, Hajar Jaberie, Fakhraddin Naghibalhossain. Carcinoembryonic Antigen Expression and Resistance to Radiation and 5-Fluorouracil-Induced Apoptosis and Autophagy. International journal of molecular and cellular medicine. vol 5. issue 2. 2016-08-01. PMID:27478804. |
mtt assay was used to measure ic50 value of the cells exposed to graded concentrations of 5- fu with either 0.1 mm nab or 1 μm 5-aza for 72 h . using cho- and sw742-cea transfectants, we also investigated the effect of cea expression on uv- and 5-fu-induced apoptosis and autophagy. |
2016-08-01 |
2023-08-13 |
Not clear |
| Jing Sun, Fangyan Wang, Haixiao Li, Huiqing Zhang, Jiangtao Jin, Wenqian Chen, Mengqi Pang, Junjie Yu, Yiwen He, Jiaming Liu, Chunfeng Li. Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice. BioMed research international. vol 2015. 2016-03-10. PMID:26064905. |
10 mg/kg nab treatment also remarkably inhibited the apoptosis, decreasing the levels of caspase-3 and bax and increasing the levels of bcl-2, p-akt, and bdnf. |
2016-03-10 |
2023-08-13 |
mouse |
| Sabbir Khan, Gopabandhu Jen. Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 73. 2015-08-03. PMID:25158305. |
the present study was aimed to investigate the renoprotective effects of sodium butyrate (nab) in diabetes-induced renal damages, apoptosis and fibrosis in juvenile rats. |
2015-08-03 |
2023-08-13 |
rat |
| Sabbir Khan, Gopabandhu Jen. Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 73. 2015-08-03. PMID:25158305. |
post-treatment with nab significantly decreased plasma glucose, creatinine, urea, histological alterations including the fibrosis and collagen deposition as well as decreased the hdacs activity, expression of enos, inos, α-sma, collagen i, fibronectin, tgfβ-1, nfκb, apoptosis and dna damage in the diabetic kidney. |
2015-08-03 |
2023-08-13 |
rat |
| Sabbir Khan, Gopabandhu Jen. Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 73. 2015-08-03. PMID:25158305. |
these results showed that nab treatment improved the renal function and ameliorated the histological alterations, fibrosis, apoptosis and dna damage in the kidney of juvenile rats. |
2015-08-03 |
2023-08-13 |
rat |
| Sabita N Saldanha, Rishabh Kala, Trygve O Tollefsbo. Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. Experimental cell research. vol 324. issue 1. 2014-07-01. PMID:24518414. |
taken together, these findings suggest that at low and physiologically achievable concentrations, combinatorial egcg and nab are effective in promoting apoptosis, inducing cell cycle arrest and dna-damage in crc cells. |
2014-07-01 |
2023-08-12 |
Not clear |