| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyan Jin, Zhengyi Wang, Wenyang Pang, Jian Zhou, Yong Liang, Jingjin Yang, Linjun Yang, Qiang Zhan. Upregulated hsa_circ_0004458 Contributes to Progression of Papillary Thyroid Carcinoma by Inhibition of miR-885-5p and Activation of RAC1. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-11. PMID:30086127. |
mtt and flow cytometry assays were used to measure the cell proliferation, cycle, and apoptosis abilities. |
2018-12-11 |
2023-08-13 |
mouse |
| Areeba Anwar, Nizam Uddin, Bina Shaheen Siddiqui, Rafat Ali Siddiqui, Sabira Begum, Muhammad Iqbal Choudhar. A natural flavonoid lawsonaringenin induces cell cycle arrest and apoptosis in HT-29 colorectal cancer cells by targeting multiple signalling pathways. Molecular biology reports. vol 45. issue 5. 2018-12-11. PMID:30088202. |
the ht-29 cells were treated with lsg or 5-fluoruracil, as a positive control, to determine its effect on cell cytotoxicity by a mtt cell proliferation assay, and cell cycle progression and apoptosis using flowcytometry. |
2018-12-11 |
2023-08-13 |
Not clear |
| Na Li, Mei Han, Ning Zhou, Yong Tang, Xu-Shan Tan. MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2). Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-11. PMID:30147110. |
in addition, chemosensitivity and proliferation were detected by mtt assay and apoptosis was assessed by flow cytometry. |
2018-12-11 |
2023-08-13 |
human |
| Fengli Zhang, Huixiao Chen, Jing Du, Bin Wang, Lixiao Yan. Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-11. PMID:30171812. |
material and methods cell viability and apoptosis were examined by mtt and annexin v/pi double staining respectively. |
2018-12-11 |
2023-08-13 |
Not clear |
| Haitao Sun, Mengfan Yin, Weiqing Qian, Hong Yi. Calycosin, a Phytoestrogen Isoflavone, Induces Apoptosis of Estrogen Receptor-Positive MG-63 Osteosarcoma Cells via the Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-11. PMID:30182951. |
cell viability and apoptosis were studied by an mtt assay and flow cytometry. |
2018-12-11 |
2023-08-13 |
mouse |
| Neng-Wen Xu, Yu Chen, Wei'e Liu, Yan-Jie Chen, Zhi-Min Fan, Min Liu, Lin-Jie L. Inhibition of JAK2/STAT3 Signaling Pathway Suppresses Proliferation of Burkitt's Lymphoma Raji Cells via Cell Cycle Progression, Apoptosis, and Oxidative Stress by Modulating HSP70. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-11. PMID:30194286. |
hsp70 expression was detected by quantitative real-time reverse transcription-pcr (qrt-pcr); the expression levels of hsp70 and jak2/stat3 pathway-related proteins were evaluated by western blotting; cell proliferation was assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assays; cell cycle distribution was observed by flow cytometry; cell apoptosis was tested by annexin v-fitc/pi and hoechst 33342/pi staining; reactive oxygen species (ros) production was measured by dichloro-dihydro-fluorescein diacetate (dcfh-da) assays; and mda content and sod and gsh-px activities were determined using detection kits. |
2018-12-11 |
2023-08-13 |
human |
| Biao Gu, Qi Wang, Weijie Dai, Gang Ma, Yaqi Song, Qingquan W. Effect of GDF11 on proliferation and apoptosis of esophageal cancer cells. Cellular and molecular biology (Noisy-le-Grand, France). vol 64. issue 11. 2018-12-11. PMID:30213293. |
moreover, gdf11 was used to treat esophageal cancer cells, and its effect on proliferation and apoptosis was determined with mtt assay and flow cytometry, respectively. |
2018-12-11 |
2023-08-13 |
Not clear |
| Yuexia Liao, Yang Xu, Mengyao Cao, Yuanyuan Huan, Lei Zhu, Ye Jiang, Weigan Shen, Guoqiang Zh. Luteolin Induces Apoptosis and Autophagy in Mouse Macrophage ANA-1 Cells via the Bcl-2 Pathway. Journal of immunology research. vol 2018. 2018-12-11. PMID:30246034. |
the viability of the cells was determined by an mtt assay, apoptosis was determined by flow cytometric analysis, the level of cell autophagy was observed by confocal microscopy, and the expression levels of apoptotic or autophagic and antiapoptotic or antiautophagic proteins were detected by western blot analysis. |
2018-12-11 |
2023-08-13 |
mouse |
| Feifei Li, Jianni Qi, Chengyong Qin, Zhaoqing Fu, Wanhua Re. Taurolidine promotes cell apoptosis by enhancing GRIM‑19 expression in liver cancer. Oncology reports. vol 40. issue 6. 2018-12-11. PMID:30272302. |
the viability and apoptosis of liver cancer cells were evaluated using the mtt assay and flow cytometry. |
2018-12-11 |
2023-08-13 |
human |
| Annie Riera-Leal, Adrián Ramírez De Arellano, Inocencia Guadalupe Ramírez-López, Edgar I Lopez-Pulido, Judith R Dávila Rodríguez, José G Macías-Barragan, Pablo César Ortiz-Lazareno, Luis Felipe Jave-Suárez, Cristina Artaza-Irigaray, Susana Del Toro Arreola, Margarita Montoya-Buelna, José Francisco Muñoz-Valle, Ana Laura Pereira-Suáre. Effects of 60 kDa prolactin and estradiol on metabolism and cell survival in cervical cancer: Co‑expression of their hormonal receptors during cancer progression. Oncology reports. vol 40. issue 6. 2018-12-11. PMID:30272319. |
proliferation was evaluated using the xcelligence platform, apoptosis was analyzed by flow cytometry and cell metabolism was determined using the mtt assay. |
2018-12-11 |
2023-08-13 |
human |
| Haifeng Fu, Feiyue Xing, Yi Lv, Boning Zeng, Pengtao You, Jing Li. ICBP90 mediates Notch signaling to facilitate human hepatocellular carcinoma growth. Tissue & cell. vol 54. 2018-12-11. PMID:30309512. |
mtt assay and flow cytometry were used to determine the proliferation, cell cycle and apoptosis of hepg2 or hepa1-6 cells treated by n-[n-(3,5-difluorophenacetyl)-l-alanyl]-s-phenylglycine t-butyl ester (dapt), a specific inhibitor of the notch pathway. |
2018-12-11 |
2023-08-13 |
human |
| Enjie Diao, Dongliang Ren, Tingwu Liu, Jianmei Zhang, Weicheng Hu, Hanxue Ho. Ozone detoxification of patulin in aqueous solution and cytotoxic evaluation using human hepatic carcinoma cells. Toxicon : official journal of the International Society on Toxinology. vol 155. 2018-12-11. PMID:30312692. |
in this study, ozone was used to degrade patulin in aqueous solution, and investigated the cytotoxicity of patulin after ozone detoxification on human hepatic carcinoma cells (hepg2) using mtt assay and apoptosis assay. |
2018-12-11 |
2023-08-13 |
human |
| Cheng-Ya Dong, Jiayue Cui, Dian-He Li, Qi Li, Xin-Yu Hon. HOXA10‑AS: A novel oncogenic long non‑coding RNA in glioma. Oncology reports. vol 40. issue 5. 2018-11-27. PMID:30132568. |
cell growth was assessed by mtt assay, and a flow cytometer was used to investigate cell proliferation, cell cycle distribution and cell apoptosis. |
2018-11-27 |
2023-08-13 |
human |
| Federica Fratangelo, Rosa Camerlingo, Maria Vincenza Carriero, Giuseppe Pirozzi, Giuseppe Palmieri, Giusy Gentilcore, Concetta Ragone, Michele Minopoli, Paolo Antonio Ascierto, Maria Letizia Mott. Effect of ABT-888 on the apoptosis, motility and invasiveness of BRAFi-resistant melanoma cells. International journal of oncology. vol 53. issue 3. 2018-11-26. PMID:29956724. |
cell viability and apoptosis were assessed by mtt assay and annexin v-fitc analysis, respectively. |
2018-11-26 |
2023-08-13 |
Not clear |
| Wei Han, Fang Cao, Xiao-Jiao Gao, Hua-Bing Wang, Fang Chen, Si-Jian Cai, Cong Zhang, Yong-Wei Hu, Jun Ma, Xing Gu, Hou-Zhong Din. ZIC1 acts a tumor suppressor in breast cancer by targeting survivin. International journal of oncology. vol 53. issue 3. 2018-11-26. PMID:29956756. |
subsequently, the mda-mb-231 and sk-br3 cells with a lower zic1 expression were transfected with rlv-zic1-pgk-puro lentivirus or rlv-zsgreen-pgk‑puro lentivirus in order to observe any alterations in cell proliferation and apoptosis through mtt assay, colony formation assay, mitochondrial membrane potential assay and flow cytometric analysis, and to analyze the modulation of molecular mechanisms by western blot analysis. |
2018-11-26 |
2023-08-13 |
mouse |
| Yongbo Song, Chao Song, Sixing Yan. Tumor-Suppressive Function of miR-30d-5p in Prostate Cancer Cell Proliferation and Migration by Targeting NT5E. Cancer biotherapy & radiopharmaceuticals. vol 33. issue 5. 2018-11-21. PMID:29916747. |
the results indicated that mir-30d-5p overexpression inhibited pca cell growth and invasion by mtt, transwell assays, respectively, as well as induced cell cycle g0/g1 phase arrest and apoptosis using flow cytometry analysis. |
2018-11-21 |
2023-08-13 |
Not clear |
| Jian-Zhong Lin, Irbaz Hameed, Zhen Xu, Yang Yu, Zhi-Yun Ren, Jia-Geng Zh. Efficacy of gefitinib‑celecoxib combination therapy in docetaxel‑resistant prostate cancer. Oncology reports. vol 40. issue 4. 2018-11-20. PMID:30066906. |
mtt, clone formation and fluorescence‑activated cell sorting (facs) analyses demonstrated that gefitinib and celecoxib in combination decreased cell viability and enhanced the rate of apoptosis when compared with either drug used alone. |
2018-11-20 |
2023-08-13 |
human |
| Dong Liu, Yifu Fan, Jun Li, Binbin Cheng, Wanfu Lin, Xiaoyan Li, Juan Du, Changquan Lin. Inhibition of cFLIP overcomes acquired resistance to sorafenib via reducing ER stress‑related autophagy in hepatocellular carcinoma. Oncology reports. vol 40. issue 4. 2018-11-20. PMID:30066934. |
the cell inhibition rate and apoptosis of cells were determined by mtt assay and flow cytometry, respectively. |
2018-11-20 |
2023-08-13 |
Not clear |
| Arunava Das, Harshadha K, Dhinesh Kannan S K, Hari Raj K, Bindhu Jayaprakas. Evaluation of Therapeutic Potential of Eugenol-A Natural Derivative of Syzygium aromaticum on Cervical Cancer Asian Pacific journal of cancer prevention : APJCP. vol 19. issue 7. 2018-11-15. PMID:30051686. |
flow cytometer determined the apoptosis confirming the cytotoxicity value for mtt at ic50 with 81.85% cellviability. |
2018-11-15 |
2023-08-13 |
human |
| Fang-Ni Chai, Wen-Yu Ma, Jian Zhang, He-Shan Xu, Yuan-Feng Li, Qi-De Zhou, Xue-Gang Li, Xiao-Li Y. Coptisine from Rhizoma coptidis exerts an anti-cancer effect on hepatocellular carcinoma by up-regulating miR-122. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 103. 2018-11-13. PMID:29710498. |
cell proliferation, migration, and apoptosis were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and colony formation assay, wound-healing assay, hoechst 33258 staining and flow cytometry, respectively. |
2018-11-13 |
2023-08-13 |
mouse |