| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinyu Hu, Shanshan Teng, Jiawei He, Xiaoqi Sun, Mingzhao Du, Ling Kou, Xiaofeng Wan. Pharmacological basis for application of scutellarin in Alzheimer's disease: Antioxidation and antiapoptosis. Molecular medicine reports. vol 18. issue 5. 2019-01-29. PMID:30221730. |
in l‑glu‑damaged ht22 cells, sc significantly increased cell viability, inhibited lactate dehydrogenase release, reduced caspase‑3 activity and suppressed apoptosis, which were determined via an mtt assay, an in vitro toxicology assay kit, a caspase‑3 activity assay kit, and propidium iodide and annexin v staining. |
2019-01-29 |
2023-08-13 |
mouse |
| Xi-Bin Hu, Shu-Hua Fu, Q I Luo, Jian-Zhong He, Yan-Fei Qiu, Wei Lai, Min Zhon. Down-regulation of microRNA-216a confers protection against yttrium aluminium garnet laser-induced retinal injury Journal of biosciences. vol 43. issue 5. 2019-01-29. PMID:30541958. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay was used to determine cell proliferation and flow cytometry was used to observe cell cycle and apoptosis. |
2019-01-29 |
2023-08-13 |
rat |
| Hucheng Chen, Jiyu Xu, Yuan Lv, Ping He, Chunyan Liu, Jie Jiao, Shiwei Li, Xuhua Mao, Xue Xu. Proanthocyanidins exert a neuroprotective effect via ROS/JNK signaling in MPTP‑induced Parkinson's disease models in vitro and in vivo. Molecular medicine reports. vol 18. issue 6. 2019-01-28. PMID:30272275. |
mtt assays were used to detect cell viability, and flow cytometry and tunel assays were used to detect cell apoptosis. |
2019-01-28 |
2023-08-13 |
mouse |
| Jing Yu, Xufen Cao, Ye Zheng, Liqiu Yan, Jiawang Wan. Abnormal expression of miR‑133a in patients with acute myocardial infarction following radical surgery for gastric cancer and the underlying mechanism. Molecular medicine reports. vol 18. issue 6. 2019-01-28. PMID:30320356. |
cell proliferation and apoptosis were subsequently detected using an mtt assay and flow cytometry. |
2019-01-28 |
2023-08-13 |
human |
| Lan Liu, Yanxin Huang, Kaili Zhang, Shupeng Song, Shuangxing Li, Yongguo Li, Yinghua La. Hepatitis B core antigen regulates dendritic cell proliferation and apoptosis through regulation of PKC/NF‑κB signaling pathway. Molecular medicine reports. vol 18. issue 6. 2019-01-28. PMID:30365118. |
mtt assay and flow cytometry (annexin v/propidium iodide analysis) were performed to investigate changes in cell proliferation and apoptosis. |
2019-01-28 |
2023-08-13 |
Not clear |
| Dandan Yi, Lei Xu, Ru Wang, Xingyi Lu, Jianfeng San. miR-381 overcomes cisplatin resistance in breast cancer by targeting MDR1. Cell biology international. vol 43. issue 1. 2019-01-25. PMID:30444043. |
the ddp sensitivity and cell apoptosis of breast cancer cells were determined by mtt assay and flow cytometric analysis, respectively. |
2019-01-25 |
2023-08-13 |
Not clear |
| Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wan. Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer. Oncology reports. vol 41. issue 1. 2019-01-22. PMID:30365143. |
the expression of smac was evaluated by western blot analysis and quantitative polymerase chain reaction, ovv‑smac cytotoxicity by mtt assay, and apoptosis by flow cytometry and western blot analysis. |
2019-01-22 |
2023-08-13 |
Not clear |
| Hua Yan, Bing-Mei Sun, Yu-Ying Zhang, Yu-Juan Li, Cheng-Xiang Huang, Fu-Zhong Feng, Cui L. Upregulation of miR-183-5p is responsible for the promotion of apoptosis and inhibition of the epithelial-mesenchymal transition, proliferation, invasion and migration of human endometrial cancer cells by downregulating Ezrin. International journal of molecular medicine. vol 42. issue 5. 2019-01-21. PMID:30226564. |
cell proliferation, cell cycle, apoptosis, migration and invasion were then evaluated using an mtt assay, flow cytometry, scratch test and transwell assay, respectively. |
2019-01-21 |
2023-08-13 |
human |
| Jafar Rezaie, Vahid Nejati, Majid Khaksar, Ahmad Oryan, Nasser Aghamohamadzadeh, Mohammad Ali Shariatzadeh, Reza Rahbarghazi, Malek Soleimani Mehranjan. Diabetic sera disrupted the normal exosome signaling pathway in human mesenchymal stem cells in vitro. Cell and tissue research. vol 374. issue 3. 2019-01-14. PMID:30073543. |
cell viability and apoptosis rate were detected by mtt and flow cytometry assays. |
2019-01-14 |
2023-08-13 |
human |
| Zhanwei Zhang, Jianbai Y. NR4A1 Promotes Cerebral Ischemia Reperfusion Injury by Repressing Mfn2-Mediated Mitophagy and Inactivating the MAPK-ERK-CREB Signaling Pathway. Neurochemical research. vol 43. issue 10. 2019-01-14. PMID:30136162. |
cellular apoptosis was determined via mtt assays, caspase-3 activity and western blotting. |
2019-01-14 |
2023-08-13 |
mouse |
| Fangyi Long, Weixin Liu, Ping Jia, Huafei Wang, Gang Jiang, Ting Wan. HIF-1α-induced autophagy contributes to cisplatin resistance in ovarian cancer cells. Die Pharmazie. vol 73. issue 9. 2019-01-14. PMID:30223937. |
in this study, the viability and apoptosis of ovarian cancer cell line ovcar-3 were assessed using mtt and flow cytometry analysis. |
2019-01-14 |
2023-08-13 |
Not clear |
| Xiao-Yu Zhang, Tsz Kin Ng, Mårten Erik Brelén, Kwok Ping Chan, Di Wu, Jasmine Sum Yee Yung, Di Cao, Yumeng Wang, Shaodan Zhang, Sun On Chan, Chi Pui Pan. Disruption of retinal pigment epithelial cell properties under the exposure of cotinine. Scientific reports. vol 7. issue 1. 2019-01-11. PMID:28600524. |
rpe cells treated with 2 μm cotinine and nicotine-cotinine mixture has lower mtt signals without significant changes in cell apoptosis or integrity. |
2019-01-11 |
2023-08-13 |
human |
| Ahmed S Sultan, Mona A Marie, Salah A Sheweit. Novel mechanism of cannabidiol-induced apoptosis in breast cancer cell lines. Breast (Edinburgh, Scotland). vol 41. 2019-01-11. PMID:30007266. |
in both cell lines, cbd inhibited cell survival and induced apoptosis in a dose dependent manner as observed by mtt assay, morphological changes, dna fragmentation and elisa apoptosis assay. |
2019-01-11 |
2023-08-13 |
human |
| Ángelo Torres, Valentina Arriagada, José Ignacio Erices, María de Los Ángeles Toro, José Dellis Rocha, Ignacio Niechi, Cristian Carrasco, Carlos Oyarzún, Claudia Quezad. FK506 Attenuates the MRP1-Mediated Chemoresistant Phenotype in Glioblastoma Stem-Like Cells. International journal of molecular sciences. vol 19. issue 9. 2019-01-11. PMID:30208561. |
apoptosis and mtt assays were employed to evaluate the cytotoxic effects of fk506 plus vincristine (mrp1 substrate). |
2019-01-11 |
2023-08-13 |
Not clear |
| Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong H. Tumor promoter role of miR‑647 in gastric cancer via repression of TP73. Molecular medicine reports. vol 18. issue 4. 2019-01-09. PMID:30106095. |
mtt, flow cytometry and transwell invasion assays were performed to investigate the proliferation, cell apoptosis, migration and invasion properties of mgc‑803 cells. |
2019-01-09 |
2023-08-13 |
Not clear |
| Jiaqin Yan, Junhui Zhang, Xudong Zhang, Xin Li, Ling Li, Zhaoming Li, Renyin Chen, Lei Zhang, Jingjing Wu, Xinhua Wang, Zhenchang Sun, Xiaorui Fu, Yu Chang, Feifei Nan, Hui Yu, Xiaolong Wu, Xiaoyan Feng, Wencai Li, Mingzhi Zhan. SPARC is down-regulated by DNA methylation and functions as a tumor suppressor in T-cell lymphoma. Experimental cell research. vol 364. issue 2. 2019-01-08. PMID:29277504. |
then cell proliferation, apoptosis, migration and invasion of t-nhl cells with either knockdown or overexpression of sparc were determined by mtt, flow cytometry, transwell migration and invasion assay, respectively. |
2019-01-08 |
2023-08-13 |
Not clear |
| Shoudong Wang, Qing Zhang, Yingcui Wang, Beian You, Qingfeng Meng, Sen Zhang, Xuanlong Li, Zhiming G. Transforming Growth Factor β1 (TGF-β1) Appears to Promote Coronary Artery Disease by Upregulating Sphingosine Kinase 1 (SPHK1) and Further Upregulating Its Downstream TIMP-1. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-01-07. PMID:30317247. |
cell apoptosis was detected by mtt assay. |
2019-01-07 |
2023-08-13 |
human |
| Fenglei Chen, Xin Wen, Pengfei Lin, Huatao Chen, Aihua Wang, Yaping Ji. HERP depletion inhibits zearalenone-induced apoptosis through autophagy activation in mouse ovarian granulosa cells. Toxicology letters. vol 301. 2019-01-07. PMID:30394307. |
in this study, mtt and flow cytometry assays demonstrated that zea gradually decreased cell viability and increased apoptosis in granulosa cells in a dose-dependent manner. |
2019-01-07 |
2023-08-13 |
mouse |
| Yanhua Chen, Yi Qin, Li Li, Jing Chen, Xu Zhang, Yubo Xi. Morphine Can Inhibit the Growth of Breast Cancer MCF-7 Cells by Arresting the Cell Cycle and Inducing Apoptosis. Biological & pharmaceutical bulletin. vol 40. issue 10. 2019-01-03. PMID:28740043. |
then, cell viability was measured through the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, and cell cycle and apoptosis assays were detected by flow cytometry (fcm). |
2019-01-03 |
2023-08-13 |
Not clear |
| Baohong Jiang, Yuehua Li, Xiaofei Qu, Hongbo Zhu, Yeru Tan, Qun Fan, Yiling Jiang, Mingchu Liao, Xiaoping W. Long noncoding RNA cancer susceptibility candidate 9 promotes doxorubicin‑resistant breast cancer by binding to enhancer of zeste homolog 2. International journal of molecular medicine. vol 42. issue 5. 2019-01-02. PMID:30106089. |
the viability, apoptosis, migration and invasion of the transfected cells were assessed via an mtt assay, flow cytometry and a transwell assay, respectively. |
2019-01-02 |
2023-08-13 |
Not clear |