| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhe Zhang, Xiaohua Zhong, Yipin Xiao, Chao Che. MicroRNA-296 inhibits colorectal cancer cell growth and enhances apoptosis by targeting ARRB1-mediated AKT activation. Oncology reports. vol 41. issue 1. 2018-12-28. PMID:30365090. |
in addition, a mir-296 mimic was transfected into crc cells, and the effects of mir-296 on cell proliferation and apoptosis were explored by mtt assay and flow cytometry. |
2018-12-28 |
2023-08-13 |
Not clear |
| Roba M El-Tabba', Princy Mathew, Willias Masocha, Maitham A Khaja. COL‑3 enhances the anti‑proliferative and pro‑apoptotic effects of paclitaxel in breast cancer cells. Oncology reports. vol 41. issue 1. 2018-12-28. PMID:30365135. |
cell proliferation, apoptosis and cell cycle stage were determined using an mtt assay, annexin v/7‑aminoactinomycin d and flow cytometry. |
2018-12-28 |
2023-08-13 |
mouse |
| J Yin, W Liu, R Li, J Liu, Y Zhang, W Tang, K Wan. IARS2 silencing induces non-small cell lung cancer cells proliferation inhibition, cell cycle arrest and promotes cell apoptosis. Neoplasma. vol 63. issue 1. 2018-12-19. PMID:26639235. |
the effects of iars2 silencing on cell growth, cell apoptosis, cell cycle and cell colony formation ability were assessed by cells counting, mtt assay, flow cytometer analysis and soft agar colony formation assay, respectively. |
2018-12-19 |
2023-08-13 |
Not clear |
| Z F Yuan, Y M Tang, X J Xu, S S Li, J Y Zhan. 10-Hydroxycamptothecin induces apoptosis in human neuroblastoma SMS-KCNR cells through p53, cytochrome c and caspase 3 pathways. Neoplasma. vol 63. issue 1. 2018-12-19. PMID:26639236. |
cell proliferation was measured by an mtt assay and apoptosis was measured using dapi staining and flow cytometric analysis. |
2018-12-19 |
2023-08-13 |
human |
| Yong Sang Lee, Seok-Mo Kim, Bup-Woo Kim, Ho Jin Chang, Soo Young Kim, Cheong Soo Park, Ki Cheong Park, Hang-Seok Chan. Anti-cancer Effects of HNHA and Lenvatinib by the Suppression of EMT-Mediated Drug Resistance in Cancer Stem Cells. Neoplasia (New York, N.Y.). vol 20. issue 2. 2018-12-18. PMID:29331886. |
cellular apoptosis and proliferation were examined by immunohistochemistry and mtt assays. |
2018-12-18 |
2023-08-13 |
mouse |
| Li-Juan Xu, Yu Duan, Peng Wang, Hui-Qing Yi. MiR-199b-5p promotes tumor growth and metastasis in cervical cancer by down-regulating KLK10. Biochemical and biophysical research communications. vol 503. issue 2. 2018-12-18. PMID:29807015. |
further, we found that transfecting mir-199 b-5p mimics into cervical cancer cells promoted tumor progression through enhancing the cell viability, migration, and suppressing apoptosis by using 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (mtt), wound healing and flow cytometry analysis. |
2018-12-18 |
2023-08-13 |
human |
| Junhong Tian, Leilei Yua. Sirtuin 6 inhibits colon cancer progression by modulating PTEN/AKT signaling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 106. 2018-12-18. PMID:29957460. |
to assess the effects of sirt6 on cell proliferation, apoptosis, invasion, and migration, 3-(4,5-dimethyl-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flow cytometry, transwell, and wound healing assays were carried out, respectively. |
2018-12-18 |
2023-08-13 |
Not clear |
| Bin Li, Cui-Min Ding, Yan-Xiao Li, Jing-Cui Peng, Nan Geng, Wen-Wen Qi. MicroRNA‑145 inhibits migration and induces apoptosis in human non‑small cell lung cancer cells through regulation of the EGFR/PI3K/AKT signaling pathway. Oncology reports. vol 40. issue 5. 2018-12-18. PMID:30226581. |
an mtt assay and flow cytometry were used to investigate cell proliferation and apoptosis, respectively. |
2018-12-18 |
2023-08-13 |
human |
| Huan Wu, Yang Chen, Qinglin Li, Yating Gao, Xingxing Zhang, Jiabing Tong, Zhiqiang Zhang, Jian Hu, Danyang Wang, Shijie Zeng, Zegeng L. Intervention effect of Qi-Yu-San-Long Decoction on Lewis lung carcinoma in C57BL/6 mice: Insights from UPLC-QTOF/MS-based metabolic profiling. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 1102-1103. 2018-12-14. PMID:30366209. |
in this study, a mtt dye reduction assay and dapi staining were first used to evaluate the cell viability and apoptosis of a549 cells with and without qysld-treatment, respectively. |
2018-12-14 |
2023-08-13 |
mouse |
| Huan Wu, Yang Chen, Qinglin Li, Yating Gao, Xingxing Zhang, Jiabing Tong, Zhiqiang Zhang, Jian Hu, Danyang Wang, Shijie Zeng, Zegeng L. Intervention effect of Qi-Yu-San-Long Decoction on Lewis lung carcinoma in C57BL/6 mice: Insights from UPLC-QTOF/MS-based metabolic profiling. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 1102-1103. 2018-12-14. PMID:30366209. |
as a result, the mtt dye reduction assay and dapi staining demonstrated that qysld could inhibit the proliferation and induce the apoptosis of a549 cells. |
2018-12-14 |
2023-08-13 |
mouse |
| Weifeng Yang, Houting Zhang, Lin Xi. A novel design of HA-coated nanoparticles co-encapsulating plasmid METase and 5-Fu shows enhanced application in targeting gastric cancer stem cells. Biological chemistry. vol 399. issue 3. 2018-12-13. PMID:29016350. |
mtt and transwell assays were used to determine cell viability and apoptosis. |
2018-12-13 |
2023-08-13 |
Not clear |
| Zhi Chen, Chunyu Shi, Shuohui Gao, Defeng Song, Ye Fen. Impact of protamine I on colon cancer proliferation, invasion, migration, diagnosis and prognosis. Biological chemistry. vol 399. issue 3. 2018-12-13. PMID:29140788. |
cell viability, cell apoptosis and cell cycle were tested using the mtt assay and flow cytometry. |
2018-12-13 |
2023-08-13 |
Not clear |
| Siwei Liu, Huajiang Lei, Fangyuan Luo, Yilin Li, Lan Xi. The effect of lncRNA HOTAIR on chemoresistance of ovarian cancer through regulation of HOXA7. Biological chemistry. vol 399. issue 5. 2018-12-13. PMID:29455183. |
how hotair downregulation affected cell proliferation, migration and invasion, and apoptosis were determined using the mtt assay and the colony formation assay, the transwell assay and flow cytometry analysis, respectively. |
2018-12-13 |
2023-08-13 |
mouse |
| Swayamsiddha Kar, Dipta Sengupta, Moonmoon Deb, Nibedita Pradhan, Samir Kumar Patr. SOX2 function and Hedgehog signaling pathway are co-conspirators in promoting androgen independent prostate cancer. Biochimica et biophysica acta. Molecular basis of disease. vol 1863. issue 1. 2018-12-11. PMID:27816521. |
changes in level of cell proliferation, migration and apoptosis profiles were measured by mtt, facs, chromatin condensation and scratch assays respectively. |
2018-12-11 |
2023-08-13 |
human |
| Xue Zhou, Dihan Lu, Wen-da Li, Xiao-Hui Chen, Xiao-Yu Yang, Xi Chen, Zhi-Bin Zhou, Jiang-Hong Ye, Xia Fen. Sevoflurane Affects Oxidative Stress and Alters Apoptosis Status in Children and Cultured Neural Stem Cells. Neurotoxicity research. vol 33. issue 4. 2018-12-11. PMID:29071560. |
mtt assay and tunel staining were performed, and the mrna levels of antioxidant enzymes and apoptosis indicators were evaluated by qrt-pcr. |
2018-12-11 |
2023-08-13 |
Not clear |
| Biao Zhang, Dan-Dan Guo, Jia-Ying Zheng, Yan-An W. Expression of KLF6-SV2 in colorectal cancer and its impact on proliferation and apoptosis. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). vol 27. issue 1. 2018-12-11. PMID:29084019. |
cell proliferation, cell cycle and apoptosis were measured respectively using mtt assay, dna ploidy detection and annexin v flow cytometry. |
2018-12-11 |
2023-08-13 |
Not clear |
| Bing-Gang Zhou, Chang-Sheng Wei, Song Zhang, Zhi Zhang, Huan-Min Ga. Matrine reversed multidrug resistance of breast cancer MCF-7/ADR cells through PI3K/AKT signaling pathway. Journal of cellular biochemistry. vol 119. issue 5. 2018-12-11. PMID:29130495. |
methyl thiazolyl tetrazolium (mtt) assay was used to detect the inhibitory action; annexin v to detect apoptosis; fluorospectrophotometry to examine intracellular adriamycin (adr) accumulation; and western blot to label the proteins of p-glycoprotein (p-gp), mrp1, pten, p-akt, bcl-2, bax, and caspase-3. |
2018-12-11 |
2023-08-13 |
Not clear |
| Nada K Sedky, Zaynab H El Gammal, Amir E Wahba, Eman Mosad, Zahraa Y Waly, Amira Ali El-Fallal, Reem K Arafa, Nagwa El-Badr. The molecular basis of cytotoxicity of α-spinasterol from Ganoderma resinaceum: Induction of apoptosis and overexpression of p53 in breast and ovarian cancer cell lines. Journal of cellular biochemistry. vol 119. issue 5. 2018-12-11. PMID:29143969. |
the anti-tumor activity of α-spinasterol, isolated from the mycelial extract of the egyptian g. resinaceum, on human breast and ovarian cancer cell lines was evaluated by mtt cell viability assay and annexinv/propidium iodide apoptosis assay. |
2018-12-11 |
2023-08-13 |
human |
| N Sanoj Rejinold, Yunho Han, Jisang Yoo, Hae Yong Seok, Ji Ho Park, Yeu-Chun Ki. Evaluation of cell penetrating peptide coated Mn:ZnS nanoparticles for paclitaxel delivery to cancer cells. Scientific reports. vol 8. issue 1. 2018-12-11. PMID:29382898. |
the developed ptx loaded mn:zns nps with different cpps (pen, pvec and r9) showed enhanced anti-cancer effect compared to bare ptx, which has been validated by mtt assay followed by apoptosis assay and dna fragmentation analysis. |
2018-12-11 |
2023-08-13 |
Not clear |
| Ioannis Gkouveris, Nikolaos G Nikitakis, Jaya Aseervatham, Kalu U E Ogburek. The tumorigenic role of DSPP and its potential regulation of the unfolded protein response and ER stress in oral cancer cells. International journal of oncology. vol 53. issue 4. 2018-12-11. PMID:30015841. |
cell viability, apoptosis and migration were monitored by mtt assay, annexin v-fluorescein isothiocyanate flow cytometry and wound-healing assay, respectively. |
2018-12-11 |
2023-08-13 |
human |