| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yehan Zhu, Xianrong Du, Huaxin Chen, Yufeng Xie, Weihua Sheng, Jicheng Yan. [Effect of adenovirus-mediated ING4 and IL-24 co-expression on chemosensitivity to human lung adenocarcinoma in vitro and in vivo]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 27. issue 1. 2012-02-23. PMID:21553494. |
the growth inhibition, apoptosis rate and apoptosis body were measured by mtt, flow cytometry and hoechst staining respectively. |
2012-02-23 |
2023-08-12 |
mouse |
| Lili Jiang, Qin Huang, Jihong Chang, Enhua Wang, Xueshan Qi. MicroRNA HSA-miR-125a-5p induces apoptosis by activating p53 in lung cancer cells. Experimental lung research. vol 37. issue 7. 2012-02-14. PMID:21777146. |
in gain-of-function experiments, the authors found that hsa-mir-125a-5p suppressed proliferation and induced apoptosis in a549 cells by mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and flow cytometry, respectively. |
2012-02-14 |
2023-08-12 |
human |
| T Sliwinski, L Markiewicz, P Rusin, J Kabzinski, L Dziki, J Milonski, J Olszewski, J Blaszczyk, J Szemraj, I Majstere. Impaired nucleotide excision repair pathway as a possible factor in pathogenesis of head and neck cancer. Mutation research. vol 716. issue 1-2. 2012-02-07. PMID:21875606. |
mtt assay was used to analyse cell viability and the annexin v-fitc kit specific for kinase-3 was employed to determine apoptosis after treating the cells with uv-radiation at dose range from 0.5 to 60j/m(2). |
2012-02-07 |
2023-08-12 |
Not clear |
| Tianhong Zhang, Ming Liu, Chunrui Wang, Chao Lin, Yanan Sun, Dejun Ji. Down-regulation of MiR-206 promotes proliferation and invasion of laryngeal cancer by regulating VEGF expression. Anticancer research. vol 31. issue 11. 2012-02-07. PMID:22110210. |
mtt, matrigel invasion assays and flow cytometry methods were used to test the proliferation, invasion and apoptosis of mir-206 transfection lscc cells and a mouse model was used to investigate tumorigenesis. |
2012-02-07 |
2023-08-12 |
mouse |
| Amalia Azzariti, Anna E Quatrale, Letizia Porcelli, Nicola A Colabufo, Mariangela Cantore, Giuseppe Cassano, Giuseppe Gasparre, Giuseppina Iannelli, Stefania Tommasi, Maria A Panaro, Angelo Paradis. MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment. European journal of pharmacology. vol 670. issue 1. 2012-02-06. PMID:21925160. |
in breast and colon cancer cell lines, cell growth and apoptosis were measured by mtt assay and dna laddering elisa kit, respectively. |
2012-02-06 |
2023-08-12 |
Not clear |
| Aimin Leng, Jing Yang, Ting Liu, Jianfang Cui, Xiu-Hua Li, Yanan Zhu, Ting Xiong, Yuxiang Che. Nanoparticle-delivered VEGF-silencing cassette and suicide gene expression cassettes inhibit colon carcinoma growth in vitro and in vivo. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 32. issue 6. 2012-02-02. PMID:21761115. |
cell proliferation was measured by mtt assay, and apoptosis was detected by flow cytometry. |
2012-02-02 |
2023-08-12 |
Not clear |
| Balu Muthaiyah, Musthafa M Essa, Ved Chauhan, Abha Chauha. Protective effects of walnut extract against amyloid beta peptide-induced cell death and oxidative stress in PC12 cells. Neurochemical research. vol 36. issue 11. 2012-01-27. PMID:21706234. |
walnut extract reduced aβ-mediated cell death assessed by mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) reduction, and release of lactate dehydrogenase (membrane damage), dna damage (apoptosis) and generation of ros in a concentration-dependent manner. |
2012-01-27 |
2023-08-12 |
Not clear |
| Yi-Tao Chen, Qun-Ying Lu, Mei-Ai Lin, Dong-Qing Cheng, Zhi-Shan Ding, Le-Tian Sha. A PVP-extract fungal protein of Omphalia lapideacens and its antitumor activity on human gastric tumors and normal cells. Oncology reports. vol 26. issue 6. 2012-01-27. PMID:21894437. |
to evaluate the in vitro antitumor activity of ppeop in human gastric tumor cells (mc-4 and sgc-7901) and normal cells (mc-1), mtt assay and fcm assay were used and the morphological changes, cell viability, cell death rate and cell apoptosis rate of mc-4, sgc-7901 and mc-1 cells were estimated. |
2012-01-27 |
2023-08-12 |
human |
| Zumin Xu, Shuhuan Fang, Yufang Zuo, Yang Zhang, Rui Cheng, Qingsong Wang, Zhonghan Yang, Weibin Cai, Jianxing Ma, Xia Yang, Guoquan Ga. Combination of pigment epithelium-derived factor with radiotherapy enhances the antitumor effects on nasopharyngeal carcinoma by downregulating vascular endothelial growth factor expression and angiogenesis. Cancer science. vol 102. issue 10. 2012-01-26. PMID:21707863. |
pigment epithelium-derived factor had no effects on the proliferation and apoptosis of npc cell lines by mtt and flow cytometry assay. |
2012-01-26 |
2023-08-12 |
mouse |
| Renzo F Martino, Roberto C Davicino, María A Mattar, Yolanda A Casali, Silvia G Correa, Blas Micalizz. In vivo effect of three fractions of Larrea divaricata Cav. (jarilla) on the innate immune system: macrophage response against Candida albicans. Mycoses. vol 54. issue 6. 2012-01-23. PMID:21615533. |
cell viability was assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) test, apoptosis was evaluated using giemsa, acridine orange/ethidium bromide and ladder assay, oxidative burst was assayed using nitroblue tetrazolium test and nitrite production using griess assay. |
2012-01-23 |
2023-08-12 |
mouse |
| Pei Li, Che Chen, Ya-Ming Xi, Hao Zhang, Ming Li, Wei Den. [Apoptosis-inducing effect of clostridium difficile toxin A on K562 cells and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 3. 2012-01-19. PMID:21729540. |
the proliferative activity of k562 cells exposed to tcd a was tested by mtt assay, cell apoptosis was detected by flow cytometry; immunocytochemistry and colorimetric assay were employed to detect the protein expressions of bcl-2/bax and the activity of caspase-3, respectively. |
2012-01-19 |
2023-08-12 |
Not clear |
| Xiao-Feng Li, Jing-He Li, Chun-Hong Wang, Xiu-Li Wang, Qiu-Ju Liu, Wen Xu, Bo Jia, Lin Qiu, Jun M. [Apoptosis of KBM5R cell line with T315I point mutation induced by arsenic trioxide]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 3. 2012-01-19. PMID:21729541. |
resistance of kbm5r cells to im and proliferation of kbm5 and kbm5r cells treated with ato were detected by mtt; apoptosis of kbm5 and kbm5r cells were quantified by flow cytometry; the expression of apoptosis-related protein caspase-3, -8, -9 was determined by western blot. |
2012-01-19 |
2023-08-12 |
Not clear |
| Lu Han, Jian Zhou, Yong-Ping Song, Bai-Jun Fang, Xing-Hu Zhu, Yu-Fu Li, Xu-Dong We. [Hyperthermia increases the sensitivity of RPMI 8226 cells to adriamycin]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 3. 2012-01-19. PMID:21729549. |
rpmi 8226 cells were divided into 4 groups: control group, hyperthermia (42°c) group, chemotherapy (adm) group and combination group (42°c + adm), the survival rate of rpmi 8226 cells in 4 groups was detected by trypan blue exclusion, the inhibitory effect of hyperthermia on proliferation of rpmi 8226 cells was detected by mtt assay, the cell cycle distribution, apoptosis rate of cells, intracellular adm concentration and p-gp expression level were measured by flow cytometry. |
2012-01-19 |
2023-08-12 |
Not clear |
| Xiao-Yan Zhang, Qing-Xian Bai, Gao-Sheng Huang, Hui Zhao, Juan-Juan Chen, Li-Jie Yan. [Effect of curcumin in combination with bortezomib on proliferation and apoptosis of human multiple myeloma cell line H929 and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 3. 2012-01-19. PMID:21729550. |
mtt assay was applied to detect the inhibitory effects of curcumin and bortezomib either alone or combined at different concentrations on h929 cells, and flow cytometry was employed to assay the apoptosis rate. |
2012-01-19 |
2023-08-12 |
human |
| Shao-Xiang Wang, Huai-Qiang Ju, Kai-Sheng Liu, Jia-Xuan Zhang, Xiao Wang, Yang-Fei Xiang, Rui Wang, Jin-Yun Liu, Qiu-Ying Liu, Min Xia, Guo-Wen Xing, Zhong Liu, Yi-Fei Wan. SNX-2112, a novel Hsp90 inhibitor, induces G2/M cell cycle arrest and apoptosis in MCF-7 cells. Bioscience, biotechnology, and biochemistry. vol 75. issue 8. 2012-01-17. PMID:21821931. |
the results of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometric analysis suggest that snx-2112 inhibits cell growth in a time- and dose-dependent manner more potently than 17-(allylamino)-17-demethoxygeldanmycin (17-aag), a traditional hsp90 inhibitor, probably as a result of cell-cycle arrest at the g2/m phase and the induction of apoptosis. |
2012-01-17 |
2023-08-12 |
human |
| Ping Yang, Jing Wang, Hong-Mei Jing, Xiao-Yan K. [Effect of magnetic nanoparticle of Fe3O4 combined with daunorubicin on lymphoma cell line Raji]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 2. 2012-01-12. PMID:21518493. |
the raji cells were cultured with fe3o4-magnetic nanoparticle and daunorubicin polymerized by means of mechanical absorption, the cell viability was detected by mtt and trypan-blue exclusion; the apoptosis was detected by flow cytometry, the expressions of p53 and p65 are measured by western blot. |
2012-01-12 |
2023-08-12 |
Not clear |
| Xi-Ming Xu, Jun-Jian Deng, Guang-Jin Yuan, Fang Yang, Hong-Ting Guo, Miao Xiang, Wei Ge, Yao-Gui W. 5-Lipoxygenase contributes to the progression of hepatocellular carcinoma. Molecular medicine reports. vol 4. issue 6. 2012-01-09. PMID:21833474. |
cell viability and apoptosis were determined in hepg2 cells by mtt assay and flow cytometry, respectively. |
2012-01-09 |
2023-08-12 |
human |
| Teresa Mencherini, Patrizia Picerno, Michela Festa, Paola Russo, Anna Capasso, Rita Aquin. Triterpenoid constituents from the roots of Paeonia rockii ssp. rockii. Journal of natural products. vol 74. issue 10. 2012-01-09. PMID:21954959. |
the effects of this chloroform-soluble extract and its major constituents on cell proliferation and apoptosis of a panel of human cancer cell lines (melanoma m-14, colon cancer ht-29, breast cancer mcf-7) were evaluated by the mtt bioassay and propidium iodide staining, respectively, in comparison with normal human embryonic kidney cells (hek-293). |
2012-01-09 |
2023-08-12 |
human |
| J Zhou, Z-X Zhang, H Zhao, D-M Zhu, Y Zhang, D-C L. Anti-angiogenesis by lentivirus-mediated small interfering RNA silencing of angiopoietin-2 gene in pancreatic carcinoma. Technology in cancer research & treatment. vol 10. issue 4. 2012-01-06. PMID:21728393. |
mtt assay and flow cytometry were used to detect the cell growth and apoptosis. |
2012-01-06 |
2023-08-12 |
mouse |
| J Zhou, Z-X Zhang, H Zhao, D-M Zhu, Y Zhang, D-C L. Anti-angiogenesis by lentivirus-mediated small interfering RNA silencing of angiopoietin-2 gene in pancreatic carcinoma. Technology in cancer research & treatment. vol 10. issue 4. 2012-01-06. PMID:21728393. |
meanwhile, no obvious cell viability and apoptosis changes were found in mtt assay and flow cytometry, respectively. |
2012-01-06 |
2023-08-12 |
mouse |