All Relations between apoptosis and foxo3a

Publication Sentence Publish Date Extraction Date Species
Qin-Qin Liu, Gui-Hua Wu, Xiao-Chun Wang, Xiao-Wen Xiong, Rui-Wang, Bao-Le Ya. The role of Foxo3a in neuron-mediated cognitive impairment. Frontiers in molecular neuroscience. vol 17. 2024-07-04. PMID:38962803. the regulatory cascade of foxo3a transactivation implicates multiple downstream signaling pathways encompassing mitochondrial function, oxidative stress, autophagy, and apoptosis, collectively affecting neuronal activity. 2024-07-04 2024-07-10 human
Xiao-Dan Hao, Jin-Xiu Liu, Jing-Sai Zhan. Longevity factor FOXO3a: A potential therapeutic target for age-related ocular diseases. Life sciences. 2024-06-07. PMID:38848943. the forkhead box protein o3 (foxo3a) belongs to the subgroup o of the forkhead transcription factor family and plays an important role in regulating the aging process by participating in the regulation of various life processes, including cell cycle arrest, apoptosis, autophagy, oxidative stress, and dna repair. 2024-06-07 2024-06-10 Not clear
Ya Wen, Yan Li, Jinli Guo, Kaijian Shan. Expression of FoxO3a in sepsis mice and its association with lymphocyte apoptosis. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 5. 2024-05-30. PMID:38814205. expression of foxo3a in sepsis mice and its association with lymphocyte apoptosis. 2024-05-30 2024-06-08 mouse
Ya Wen, Yan Li, Jinli Guo, Kaijian Shan. Expression of FoxO3a in sepsis mice and its association with lymphocyte apoptosis. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 5. 2024-05-30. PMID:38814205. this study investigated forkhead box o3a (foxo3a) expression in peripheral blood of sepsis mice and its correlation with lymphocyte apoptosis. 2024-05-30 2024-06-08 mouse
Ya Wen, Yan Li, Jinli Guo, Kaijian Shan. Expression of FoxO3a in sepsis mice and its association with lymphocyte apoptosis. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 5. 2024-05-30. PMID:38814205. in sepsis mice, inhibited foxo3a signaling in lymphocytes leads to enhanced apoptosis, elevated ros, and immune cell dysfunction, contributing to increased mortality. 2024-05-30 2024-06-08 mouse
Amira A El-Gazar, Soad Z El-Emam, Shorouk M El-Sayyad, Shereen S El-Mancy, Sahar M Fayez, Nermin M Sheta, Asmaa K Al-Mokaddem, Ghada M Raga. Pegylated polymeric micelles of boswellic acid-selenium mitigates repetitive mild traumatic brain injury: Regulation of miR-155 and miR-146a/BDNF/ Klotho/Foxo3a cue. International immunopharmacology. vol 134. 2024-05-05. PMID:38705029. besides, connexin43 (cx43) expression as well as klotho and brain-derived neurotrophic factor (bdnf) were upregulated with diminished neuronal cell death and apoptosis because of reduced forkhead box class o3a(foxo3a) expression in the pmbs-treated group. 2024-05-05 2024-05-08 rat
Mohamed S Abdel-Bakky, Hamdoon A Mohammed, Nesreen I Mahmoud, Elham Amin, Mansour Alsharidah, Osamah Al Rugaie, Mohamed G Ewee. Targeting the PI3K/pAKT/mTOR/NF-κB/FOXO3a signaling pathway for suppressing the development of hepatocellular carcinoma in rats: Role of the natural remedic Suaeda vermiculata forssk. Environmental toxicology. 2024-03-20. PMID:38506534. liver toxicity and tumor markers (hgfr, p-akt, pi3k, mtor, nf-κb, foxo3a), apoptosis markers, and histopathological changes were analyzed. 2024-03-20 2024-03-23 rat
Wenqiu Mei, Bingyin Mei, Jing Chang, Yifei Liu, Yanhong Zhou, Ni Zhu, Meichun H. Role and regulation of FOXO3a: new insights into breast cancer therapy. Frontiers in pharmacology. vol 15. 2024-03-20. PMID:38505423. foxo3a plays a pivotal role in various cellular processes, including apoptosis, proliferation, cell cycle regulation, and drug resistance. 2024-03-20 2024-03-23 Not clear
Statement of Retraction: Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling. Bioengineered. vol 15. issue 1. 2024-02-20. PMID:38376902. statement of retraction: dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box o3a (foxo3a)/p53-upregulated modulator of apoptosis (puma) signaling signaling. 2024-02-20 2024-02-22 Not clear
Rasha Abdelhady, Osama A Mohammed, Ahmed S Doghish, Rabab S Hamad, Mustafa Ahmed Abdel-Reheim, Mohannad Mohammad S Alamri, Muffarah Hamid Alharthi, Jaber Alfaifi, Masoud I E Adam, Abdullah Hassan Alhalafi, Nahid A Mohammed, Adamu Imam Isa, Sameh Abdel-Ghany, Mohammed A Attia, Elsayed A Elmorsy, Tohada M Al-Noshokaty, Yousra Nomier, Walaa A El-Dakroury, Sameh Sabe. Linagliptin, a DPP-4 inhibitor, activates AMPK/FOXO3a and suppresses NFκB to mitigate the debilitating effects of diethylnitrosamine exposure in rat liver: Novel mechanistic insights. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 4. 2024-02-14. PMID:38354025. foxo3a inactivation, driven by oncogenic stimuli, can lead to abnormal cell growth, suppression of apoptosis, and resistance to anticancer drugs. 2024-02-14 2024-02-16 rat
Xinwan Wu, Yu Zhou, Hongjiao Xu, Xinyi Zhang, Liangfang Yao, Jinbao Li, Xiang L. PRMT6-FoxO3a attenuates apoptosis by upregulating Parkin expression in intestinal ischemia-reperfusion injury. Shock (Augusta, Ga.). 2024-02-07. PMID:38323918. this study aims to investigate the potential regulatory mechanisms involving protein arginine methyltransferase 6 (prmt6), forkhead box o3a (foxo3a), and parkin in iiri and elucidate their roles in mediating cell apoptosis. 2024-02-07 2024-02-09 mouse
Xinwan Wu, Yu Zhou, Hongjiao Xu, Xinyi Zhang, Liangfang Yao, Jinbao Li, Xiang L. PRMT6-FoxO3a attenuates apoptosis by upregulating Parkin expression in intestinal ischemia-reperfusion injury. Shock (Augusta, Ga.). 2024-02-07. PMID:38323918. altogether, our results demonstrated that prmt6 upregulated the expression of parkin by regulating foxo3a methylation level, attenuating the apoptosis induced by iiri. 2024-02-07 2024-02-09 mouse
Shajidan Abudureyimu, Chunhui He, Wei Xie, Zhuo Chen, Halisha Airikenjiang, Dilihumaer Abulaiti, Yan Cao, Haitang Qiu, Ying G. FOXO3a functions as a transcriptional and co-transcriptional splicing regulator in vascular endothelial cell lines. Gene. 2024-01-29. PMID:38286271. recent studies have indicated a connection between forkhead box o3a protein and coronary artery disease, yet the exact role of foxo3a in the regulation of metabolic processes and apoptosis in vascular endothelial cells is still unknown. 2024-01-29 2024-02-01 human
Zhiqiang Dong, Zongming Guo, Hui Li, Dequan Han, Wei Xie, Shaoning Cui, Wei Zhang, Shuhong Huan. FOXO3a-interacting proteins' involvement in cancer: a review. Molecular biology reports. vol 51. issue 1. 2024-01-25. PMID:38270719. due to its role in apoptosis, differentiation, cell cycle arrest, and dna damage repair in stress responses (oxidative stress, hypoxia, chemotherapeutic drugs, and uv irradiation or radiotherapy), foxo3a is considered a key tumor suppressor that determines radiotherapeutic and chemotherapeutic responses in cancer cells. 2024-01-25 2024-01-27 Not clear
Kuan-Ho Lin, Shang-Chuan Ng, Shang-Yeh Lu, Yueh-Min Lin, Shu-Hui Lin, Tzu-Cheng Su, Chih-Yang Huang, Wei-Wen Ku. Diallyl trisulfide (DATS) protects cardiac cells against advanced glycation end-product-induced apoptosis by enhancing FoxO3A-dependent upregulation of miRNA-210. The Journal of nutritional biochemistry. 2024-01-07. PMID:38185348. we investigated the dats-mediated attenuation mechanism of age-enhanced cardiac apoptosis by modulating mir-210 and its upstream transcriptional regulator, foxo3a. 2024-01-07 2024-01-10 Not clear
Kuan-Ho Lin, Shang-Chuan Ng, Shang-Yeh Lu, Yueh-Min Lin, Shu-Hui Lin, Tzu-Cheng Su, Chih-Yang Huang, Wei-Wen Ku. Diallyl trisulfide (DATS) protects cardiac cells against advanced glycation end-product-induced apoptosis by enhancing FoxO3A-dependent upregulation of miRNA-210. The Journal of nutritional biochemistry. 2024-01-07. PMID:38185348. we also showed that foxo3a, upregulated by dats treatment, may bind to the mir-210 promoter to enhance its expression and downregulates jnk expression to attenuate age-induced cardiac apoptosis. 2024-01-07 2024-01-10 Not clear
Kuan-Ho Lin, Shang-Chuan Ng, Shang-Yeh Lu, Yueh-Min Lin, Shu-Hui Lin, Tzu-Cheng Su, Chih-Yang Huang, Wei-Wen Ku. Diallyl trisulfide (DATS) protects cardiac cells against advanced glycation end-product-induced apoptosis by enhancing FoxO3A-dependent upregulation of miRNA-210. The Journal of nutritional biochemistry. 2024-01-07. PMID:38185348. oral administration of dats enhanced foxo3a expression in the heart and reduced diabetes-induced heart apoptosis. 2024-01-07 2024-01-10 Not clear
Kuan-Ho Lin, Shang-Chuan Ng, Shang-Yeh Lu, Yueh-Min Lin, Shu-Hui Lin, Tzu-Cheng Su, Chih-Yang Huang, Wei-Wen Ku. Diallyl trisulfide (DATS) protects cardiac cells against advanced glycation end-product-induced apoptosis by enhancing FoxO3A-dependent upregulation of miRNA-210. The Journal of nutritional biochemistry. 2024-01-07. PMID:38185348. our findings indicate that dats mediates age-induced cardiac cell apoptosis attenuation by promoting foxo3a nuclear transactivation to enhance mir-210 expression and regulate jnk activation. 2024-01-07 2024-01-10 Not clear
Suryaa Manoharan, Kunjkumar Prajapati, Ekambaram Peruma. Natural bioactive compounds and FOXO3a in cancer therapeutics: An update. Fitoterapia. 2024-01-03. PMID:38168566. foxo3a promotes its anticancer effects by upregulating the levels of its downstream targets, including bim, fasl, and bax, leading to apoptosis. 2024-01-03 2024-01-06 Not clear
Jian-Heng Hao, Yue-Meng Zhao, Hai-Jun Wang, Yu-Xia Cao, Ying Lan, Lai-Xi J. [Mechanism of protective effect of resveratrol on poor ovarian response in mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 21. 2023-12-19. PMID:38114185. animal experiments showed that the model group had higher rate of estrous cycle disorders, lower number and poorer morphology of normally developed follicles at all levels, more atretic follicles, higher apoptosis of ovarian granulosa cells, lower number of retrieved oocytes, lower ovarian wet weight and ovarian index, higher serum levels of fsh and lh, lower levels of amh and e_2, higher expression levels of hif-1α, foxo3a and bax, and lower expression levels of pi3k, akt, and bcl-2 in the ovarian tissue than the normal group. 2023-12-19 2023-12-23 mouse