| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R E Felgar, K R Steward, J B Cousar, W R Maco. T-cell-rich large-B-cell lymphomas contain non-activated CD8+ cytolytic T cells, show increased tumor cell apoptosis, and have lower Bcl-2 expression than diffuse large-B-cell lymphomas. The American journal of pathology. vol 153. issue 6. 1998-12-29. PMID:9846961. |
we studied 18 tcrbcls and 12 diffuse large-b-cell lymphomas (dlbcls) to compare the 1) predominant t cell subpopulation(s), 2) expression of cytotoxic granule proteins (tia-1 and granzyme b), 3) level of tumor cell apoptosis (apoptag system, oncor, gaithersburg, md), and 4) expression of ki-67 (mib-1) and apoptosis-related proteins (fas (cd95), bcl-2, and p53). |
1998-12-29 |
2023-08-12 |
Not clear |
| N Mitsiades, V Poulaki, V Kotoula, A Leone, M Tsoko. Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloproteinase. The American journal of pathology. vol 153. issue 6. 1998-12-29. PMID:9846984. |
fas ligand (fasl) exists in transmembrane and soluble forms and induces apoptosis on cross-linking with the fas receptor. |
1998-12-29 |
2023-08-12 |
Not clear |
| D L Crowe, M L Boardman, K S Fon. Anti-Fas antibody differentially regulates apoptosis in Fas ligand resistant carcinoma lines via the caspase 3 family of cell death proteases but independently of bcl2 expression. Anticancer research. vol 18. issue 5A. 1998-12-29. PMID:9858879. |
anti-fas antibody differentially regulates apoptosis in fas ligand resistant carcinoma lines via the caspase 3 family of cell death proteases but independently of bcl2 expression. |
1998-12-29 |
2023-08-12 |
Not clear |
| D L Crowe, M L Boardman, K S Fon. Anti-Fas antibody differentially regulates apoptosis in Fas ligand resistant carcinoma lines via the caspase 3 family of cell death proteases but independently of bcl2 expression. Anticancer research. vol 18. issue 5A. 1998-12-29. PMID:9858879. |
we concluded that fas differentially mediates apoptosis in scc lines by activation of caspase 3 family members but independent of bcl2 expression. |
1998-12-29 |
2023-08-12 |
Not clear |
| C P Leo, S Y Hsu, E A McGee, M Salanova, A J Hsue. DEFT, a novel death effector domain-containing molecule predominantly expressed in testicular germ cells. Endocrinology. vol 139. issue 12. 1998-12-24. PMID:9832420. |
death factors such as fas ligand induce apoptosis by triggering a series of intracellular protein-protein interactions mediated by defined motifs found in the signaling molecules. |
1998-12-24 |
2023-08-12 |
human |
| S M Quirk, D A Porter, S C Huber, R G Cowa. Potentiation of Fas-mediated apoptosis of murine granulosa cells by interferon-gamma, tumor necrosis factor-alpha, and cycloheximide. Endocrinology. vol 139. issue 12. 1998-12-24. PMID:9832422. |
the fas antigen is a transmembrane receptor belonging to the tumor necrosis factor-alpha (tnf) receptor family that, when activated by fas ligand or agonistic antibodies, induces death by apoptosis. |
1998-12-24 |
2023-08-12 |
mouse |
| E Lepri, D V Delfino, G Migliorati, R Moraca, E Ayroldi, C Riccard. Functional expression of Fas on mouse bone marrow stromal cells: upregulation by tumor necrosis factor-alpha and interferon-gamma. Experimental hematology. vol 26. issue 13. 1998-12-24. PMID:9845375. |
functional studies demonstrated that fas induced a strong increase in apoptosis when engaged with an anti-fas monoclonal antibody (moab). |
1998-12-24 |
2023-08-12 |
mouse |
| T Papo, C Parizot, M Ortova, J C Piette, C Frances, P Debre, P Godeau, G Gorocho. Apoptosis and expression of soluble Fas mRNA in systemic lupus erythematosus. Lupus. vol 7. issue 7. 1998-12-23. PMID:9796847. |
apoptosis and expression of soluble fas mrna in systemic lupus erythematosus. |
1998-12-23 |
2023-08-12 |
human |
| T Papo, C Parizot, M Ortova, J C Piette, C Frances, P Debre, P Godeau, G Gorocho. Apoptosis and expression of soluble Fas mRNA in systemic lupus erythematosus. Lupus. vol 7. issue 7. 1998-12-23. PMID:9796847. |
our objective was to measure the relative proportions of messenger rnas coding for soluble and membrane-bound fas in peripheral blood mononuclear cells (pbmcs) and to quantify lymphocyte apoptosis in vitro in systemic lupus erythematosus (sle). |
1998-12-23 |
2023-08-12 |
human |
| A Druilhe, B Wallaert, A Tsicopoulos, J R Lapa e Silva, I Tillie-Leblond, A B Tonnel, M Pretolan. Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics. American journal of respiratory cell and molecular biology. vol 19. issue 5. 1998-12-23. PMID:9806739. |
apoptosis, proliferation, and expression of bcl-2, fas, and fas ligand in bronchial biopsies from asthmatics. |
1998-12-23 |
2023-08-12 |
human |
| A Druilhe, B Wallaert, A Tsicopoulos, J R Lapa e Silva, I Tillie-Leblond, A B Tonnel, M Pretolan. Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics. American journal of respiratory cell and molecular biology. vol 19. issue 5. 1998-12-23. PMID:9806739. |
the in situ apoptosis and the expression of molecules involved in this process, such as bcl-2, fas, and its ligand, fas ligand (fasl), were examined in bronchial biopsies from healthy control subjects and from steroid-untreated or -treated asthmatics, using terminal transferase-mediated deoxyuridyltriphosphate nick-end labeling and immunohistochemical techniques, respectively. |
1998-12-23 |
2023-08-12 |
human |
| A Kawahara, T Kobayashi, S Nagat. Inhibition of Fas-induced apoptosis by Bcl-2. Oncogene. vol 17. issue 20. 1998-12-23. PMID:9840917. |
jurkat cells express fas, and rapidly undergo apoptosis in response to fas ligand or an agonistic anti-fas antibody. |
1998-12-23 |
2023-08-12 |
Not clear |
| A Kawahara, T Kobayashi, S Nagat. Inhibition of Fas-induced apoptosis by Bcl-2. Oncogene. vol 17. issue 20. 1998-12-23. PMID:9840917. |
these results suggest that bcl-2 inhibits fas-induced apoptosis by preventing the formation of the death-inducing signaling complex that is composed of fas, fadd/mort1, and caspase 8. |
1998-12-23 |
2023-08-12 |
Not clear |
| J Desbarats, R C Duke, M K Newel. Newly discovered role for Fas ligand in the cell-cycle arrest of CD4+ T cells. Nature medicine. vol 4. issue 12. 1998-12-23. PMID:9846574. |
fas ligand (fasl) can induce apoptosis of fas-bearing cells. |
1998-12-23 |
2023-08-12 |
Not clear |
| M Sata, K Wals. Oxidized LDL activates fas-mediated endothelial cell apoptosis. The Journal of clinical investigation. vol 102. issue 9. 1998-12-21. PMID:9802882. |
fas ligand (fasl) is naturally expressed on the vascular endothelium where it can induce apoptosis in fas-expressing immune cells as they enter the vessel wall. |
1998-12-21 |
2023-08-12 |
mouse |
| M Sata, K Wals. Oxidized LDL activates fas-mediated endothelial cell apoptosis. The Journal of clinical investigation. vol 102. issue 9. 1998-12-21. PMID:9802882. |
although vascular endothelial cells are normally resistant to fas-mediated cell death, oxldl were shown to induce apoptosis in cultured endothelial cells and endothelium of arterial explants by a process that could be inhibited with fas l neutralizing antibodies. |
1998-12-21 |
2023-08-12 |
mouse |
| D Peritt, S Robertson, G Gri, L Showe, M Aste-Amezaga, G Trinchier. Differentiation of human NK cells into NK1 and NK2 subsets. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 11. 1998-12-21. PMID:9834059. |
although these nk cell subsets do not differ in cytotoxic activity, nk1 cells express higher levels of cell surface cd95 (fas) ag than nk2 cells and are more sensitive to ab or chemically induced apoptosis. |
1998-12-21 |
2023-08-12 |
human |
| A Bhushan, J L Kupperman, J E Stone, P J Kimberly, N S Calman, M P Hacker, R B Birge, T R Tritton, M K Newel. Drug resistance results in alterations in expression of immune recognition molecules and failure to express Fas (CD95). Immunology and cell biology. vol 76. issue 4. 1998-12-17. PMID:9723776. |
the defect in apoptosis can be overcome by anti-cancer agents or experimental manipulation that induce fas expression on the drug-resistant cells. |
1998-12-17 |
2023-08-12 |
Not clear |
| J Kawiak, G Hoser, T Skórsk. Apoptosis and some of its medical implications. Folia histochemica et cytobiologica. vol 36. issue 3. 1998-12-17. PMID:9773293. |
signals to apoptosis from outside of the cell including fas and fas ligand interaction and sphingomyelin cycle were presented. |
1998-12-17 |
2023-08-12 |
Not clear |
| A L Wagelie-Steffen, K Hartmann, H Vliagoftis, D D Metcalf. Fas ligand (FasL, CD95L, APO-1L) expression in murine mast cells. Immunology. vol 94. issue 4. 1998-12-15. PMID:9767446. |
fas ligand (fasl, cd95l, apo-1l), a type ii membrane protein belonging to the tumour necrosis factor family, induces apoptosis in fas-bearing cells. |
1998-12-15 |
2023-08-12 |
Not clear |