| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Tortorella, G Piazzolla, F Spaccavento, S Pece, E Jirillo, S Antonac. Spontaneous and Fas-induced apoptotic cell death in aged neutrophils. Journal of clinical immunology. vol 18. issue 5. 1998-12-15. PMID:9793824. |
on the basis of the strict analogies between polymorphonuclear cell (pmn) alterations in the aging and depressed functional capacities displayed by apoptotic pmn, we investigated the possible occurrence of age-associated changes in neutrophil apoptosis, either spontaneous or induced by fas antigen (cd95) activation. |
1998-12-15 |
2023-08-12 |
human |
| C Tortorella, G Piazzolla, F Spaccavento, S Pece, E Jirillo, S Antonac. Spontaneous and Fas-induced apoptotic cell death in aged neutrophils. Journal of clinical immunology. vol 18. issue 5. 1998-12-15. PMID:9793824. |
moreover, although we failed to detect fas ligand expression on pmn surface, treatment of cell cultures with antagonistic anti-fas igg1 (zb4) mabs determined a significant inhibition of spontaneous apoptosis in neutrophils from both groups of subjects, thus suggesting that the fas/fas ligand system is in fact involved in such an event. |
1998-12-15 |
2023-08-12 |
human |
| N S Chang, G Carey, N Pratt, E Chu, M O. p53 overexpression and downregulation of inter-alpha-inhibitor are associated with hyaluronidase enhancement of TNF cytotoxicity in L929 fibroblasts. Cancer letters. vol 131. issue 1. 1998-12-15. PMID:9839619. |
specifically, hyaluronidase upregulated p53 protein expression (>200%) but down regulated a p85 inter-alpha-inhibitor-like protein (>90%) in l929 cells, whereas it had no effect on the protein levels of ich-1, bcl-xl, bcl-2, fas ligand, cas (cellular apoptosis susceptible protein), tiar (an rna-binding protein) and alpha-tubulin. |
1998-12-15 |
2023-08-12 |
Not clear |
| M A Driancourt, B Thue. Control of oocyte growth and maturation by follicular cells and molecules present in follicular fluid. A review. Reproduction, nutrition, development. vol 38. issue 4. 1998-12-14. PMID:9795980. |
proteins involved in cell death (bax) or cell survival (bcl2) are present in oocytes as well as compounds (tnf alpha, fas) involved in the initiation of apoptosis. |
1998-12-14 |
2023-08-12 |
cattle |
| L B Owen-Schaub, K L van Golen, L L Hill, J E Pric. Fas and Fas ligand interactions suppress melanoma lung metastasis. The Journal of experimental medicine. vol 188. issue 9. 1998-12-14. PMID:9802983. |
apoptosis induced by fas (cd95) ligation is frequently lost during tumor progression; however, there is no direct evidence to support an association of fas loss-of-function with metastatic tumor behavior. |
1998-12-14 |
2023-08-12 |
mouse |
| B D Uhal, C Gidea, R Bargout, A Bifero, O Ibarra-Sunga, M Papp, K Flynn, G Filippato. Captopril inhibits apoptosis in human lung epithelial cells: a potential antifibrotic mechanism. The American journal of physiology. vol 275. issue 5. 1998-12-14. PMID:9815121. |
monoclonal antibodies that activate the fas receptor induced epithelial cell apoptosis as detected by chromatin condensation, nuclear fragmentation, dna fragmentation, and increased activities of caspase-1 and -3. |
1998-12-14 |
2023-08-12 |
mouse |
| G Eberl, S Jiang, Z Yu, P Schneider, G Corradin, J P Mac. An anti-CD19 antibody coupled to a tetanus toxin peptide induces efficient Fas ligand (FasL)-mediated cytotoxicity of a transformed human B cell line by specific CD4+ T cells. Clinical and experimental immunology. vol 114. issue 2. 1998-12-14. PMID:9822273. |
in addition, we provide evidence that b cell lysis is mediated by the fas apoptosis pathway, since fas (cd95), but not tumour necrosis factor receptor (tnfr) or tnf-related receptors, is expressed by the target b cells, and fasl, but not perforin, is expressed by the effector t cells. |
1998-12-14 |
2023-08-12 |
human |
| N Shinoura, Y Yoshida, A Sadata, K I Hanada, S Yamamoto, T Kirino, A Asai, H Hamad. Apoptosis by retrovirus- and adenovirus-mediated gene transfer of Fas ligand to glioma cells: implications for gene therapy. Human gene therapy. vol 9. issue 14. 1998-12-11. PMID:9759926. |
apoptosis by retrovirus- and adenovirus-mediated gene transfer of fas ligand to glioma cells: implications for gene therapy. |
1998-12-11 |
2023-08-12 |
Not clear |
| N Shinoura, Y Yoshida, A Sadata, K I Hanada, S Yamamoto, T Kirino, A Asai, H Hamad. Apoptosis by retrovirus- and adenovirus-mediated gene transfer of Fas ligand to glioma cells: implications for gene therapy. Human gene therapy. vol 9. issue 14. 1998-12-11. PMID:9759926. |
to assess this possibility, we transduced fas into u251, a glioma cell line resistant to anti-fas antibody-mediated apoptosis, and obtained transfectants with high levels of fas expression. |
1998-12-11 |
2023-08-12 |
Not clear |
| N Shinoura, Y Yoshida, A Sadata, K I Hanada, S Yamamoto, T Kirino, A Asai, H Hamad. Apoptosis by retrovirus- and adenovirus-mediated gene transfer of Fas ligand to glioma cells: implications for gene therapy. Human gene therapy. vol 9. issue 14. 1998-12-11. PMID:9759926. |
thus, retroviral induction of fas ligand into the glioma cells with high levels of fas led to the selection of cells that were resistant to fas-dependent apoptosis. |
1998-12-11 |
2023-08-12 |
Not clear |
| N Shinoura, Y Yoshida, A Sadata, K I Hanada, S Yamamoto, T Kirino, A Asai, H Hamad. Apoptosis by retrovirus- and adenovirus-mediated gene transfer of Fas ligand to glioma cells: implications for gene therapy. Human gene therapy. vol 9. issue 14. 1998-12-11. PMID:9759926. |
these resistant u251 transfectants were susceptible to fadd adenovirus (adeno-fadd)-induced apoptosis, indicating that a cascade of death signals was blocked at the steps between fas ligand and fadd. |
1998-12-11 |
2023-08-12 |
Not clear |
| N Shinoura, Y Yoshida, A Sadata, K I Hanada, S Yamamoto, T Kirino, A Asai, H Hamad. Apoptosis by retrovirus- and adenovirus-mediated gene transfer of Fas ligand to glioma cells: implications for gene therapy. Human gene therapy. vol 9. issue 14. 1998-12-11. PMID:9759926. |
as for adenoviral transduction of fas ligand into gliomas, gliomas with a relatively high level of expression of fas were remarkably sensitive to adeno-fl-induced apoptosis. |
1998-12-11 |
2023-08-12 |
Not clear |
| M Zhou, L Gu, A M Yeager, H W Findle. Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression. Leukemia. vol 12. issue 11. 1998-12-08. PMID:9823951. |
fas (apo-1/cd95) is a cell-surface protein that can mediate apoptosis upon specific ligand or antibody binding. |
1998-12-08 |
2023-08-12 |
Not clear |
| M Zhou, L Gu, A M Yeager, H W Findle. Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression. Leukemia. vol 12. issue 11. 1998-12-08. PMID:9823951. |
we therefore investigated the relationship between sensitivity to fas-mediated apoptosis and (1) fas expression, (2) p53 status, and (3) bcl-2 protein levels in pediatric all cell lines and primary leukemic cells. |
1998-12-08 |
2023-08-12 |
Not clear |
| M Zhou, L Gu, A M Yeager, H W Findle. Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression. Leukemia. vol 12. issue 11. 1998-12-08. PMID:9823951. |
these results suggest that some pediatric all cells expressing mt-p53+ may be sensitive to fas-mediated apoptosis due to high levels of fas expression and lack of bcl-2, and further suggest that molecular methods of activating fas may be useful for therapy of refractory all with the fas+/mt-p53+ phenotype. |
1998-12-08 |
2023-08-12 |
Not clear |
| P Juo, C J Kuo, J Yuan, J Bleni. Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade. Current biology : CB. vol 8. issue 18. 1998-12-07. PMID:9740801. |
fas (apo-1/cd95) is a member of the tumor necrosis factor receptor (tnf-r) family and induces apoptosis when crosslinked with either fas ligand or agonistic antibody (fas antibody). |
1998-12-07 |
2023-08-12 |
Not clear |
| I R Rifkin, P L Channavajhala, H L Kiefer, A J Carmack, E Landesman-Bollag, B C Beaudette, B Jersky, D J Salant, S T Ju, A Marshak-Rothstein, D C Seldi. Acceleration of lpr lymphoproliferative and autoimmune disease by transgenic protein kinase CK2 alpha. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 10. 1998-12-07. PMID:9820486. |
mrl-lpr/lpr mice have a fas receptor mutation that leads to abnormalities of apoptosis, lymphoproliferation, and a lupus-like autoimmune disease associated with the production of autoantibodies. |
1998-12-07 |
2023-08-12 |
mouse |
| G Mor, L S Gutierrez, M Eliza, F Kahyaoglu, A Aric. Fas-fas ligand system-induced apoptosis in human placenta and gestational trophoblastic disease. American journal of reproductive immunology (New York, N.Y. : 1989). vol 40. issue 2. 1998-12-04. PMID:9764350. |
we studied fas ligand (fasl) expression and apoptosis in normal and pathologic placentas to find out whether the fas-fasl-induced apoptosis takes place during implantation. |
1998-12-04 |
2023-08-12 |
human |
| A Kawakami, K Eguchi, N Matsuoka, M Tsuboi, T Koji, S Urayama, T Nakashima, Y Kawabe, S Nagatak. Expression and function of Fas and Fas ligand on peripheral blood lymphocytes in normal subjects. The Journal of laboratory and clinical medicine. vol 132. issue 5. 1998-12-03. PMID:9823934. |
although il-2-stimulated or pma-plus-ionomycin-stimulated pbls were positive for both fas and fasl, no significant increase in apoptosis was demonstrated in these activated pbls. |
1998-12-03 |
2023-08-12 |
human |
| A Kawakami, K Eguchi, N Matsuoka, M Tsuboi, T Koji, S Urayama, T Nakashima, Y Kawabe, S Nagatak. Expression and function of Fas and Fas ligand on peripheral blood lymphocytes in normal subjects. The Journal of laboratory and clinical medicine. vol 132. issue 5. 1998-12-03. PMID:9823934. |
in addition, treatment of pbls with il-2 or pma plus ionomycin did not change anti-fas-induced apoptosis, although these activated pbls expressed fas strongly when compared with unstimulated pbls. |
1998-12-03 |
2023-08-12 |
human |