| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Houghton, R M Korah, M R Condon, K H Ki. Apoptosis in Helicobacter pylori-associated gastric and duodenal ulcer disease is mediated via the Fas antigen pathway. Digestive diseases and sciences. vol 44. issue 3. 1999-04-07. PMID:10080136. |
this prompted us to investigate the potential role of fas in mediating h. pylori-related apoptosis. |
1999-04-07 |
2023-08-12 |
Not clear |
| J Houghton, R M Korah, M R Condon, K H Ki. Apoptosis in Helicobacter pylori-associated gastric and duodenal ulcer disease is mediated via the Fas antigen pathway. Digestive diseases and sciences. vol 44. issue 3. 1999-04-07. PMID:10080136. |
this communication presents the first evidence to implicate the fas pathway in mediating apoptosis in h. pylori-associated gastric and duodenal ulcer disease. |
1999-04-07 |
2023-08-12 |
Not clear |
| J P Xu, X Li, E Mori, M W Guo, T Mor. Aberrant expression and dysfunction of Fas antigen in MRL/MpJ-lpr/lpr murine ovary. Zygote (Cambridge, England). vol 6. issue 4. 1999-04-05. PMID:9921647. |
in lpr mice the insertion of an early transposable element (etn) into intron 2 of the fas gene, which mediates apoptosis, causes the development of massive lymphadenopathy, splenomegaly and autoimmune disease. |
1999-04-05 |
2023-08-12 |
mouse |
| M Podhorska-Okolow, M Sandri, S Zampieri, B Brun, K Rossini, U Carrar. Apoptosis of myofibres and satellite cells: exercise-induced damage in skeletal muscle of the mouse. Neuropathology and applied neurobiology. vol 24. issue 6. 1999-03-31. PMID:9888162. |
groups of five mice were sacrificed immediately after the end of the exercise, and after a rest period of 6 or 96 h. the amount of apoptosis in leg muscles was assessed by electron microscopy, by the terminal deoxynucleotidyl transferase assay and by electrophoretic detection of fragmented dna; the expression of bcl-2, bax, fas, ice, p53 and ubiquitin was examined by immunohistochemistry and western blot. |
1999-03-31 |
2023-08-12 |
mouse |
| V Pentikäinen, K Erkkilä, L Dunke. Fas regulates germ cell apoptosis in the human testis in vitro. The American journal of physiology. vol 276. issue 2. 1999-03-30. PMID:9950791. |
fas regulates germ cell apoptosis in the human testis in vitro. |
1999-03-30 |
2023-08-12 |
human |
| V Pentikäinen, K Erkkilä, L Dunke. Fas regulates germ cell apoptosis in the human testis in vitro. The American journal of physiology. vol 276. issue 2. 1999-03-30. PMID:9950791. |
thus fas appears to mediate germ cell apoptosis. |
1999-03-30 |
2023-08-12 |
human |
| K Yamada, F Ichikawa, S Ishiyama-Shigemoto, X Yuan, K Nonak. Essential role of caspase-3 in apoptosis of mouse beta-cells transfected with human Fas. Diabetes. vol 48. issue 3. 1999-03-30. PMID:10078546. |
essential role of caspase-3 in apoptosis of mouse beta-cells transfected with human fas. |
1999-03-30 |
2023-08-12 |
mouse |
| H Y Chang, X Yang, D Baltimor. Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 4. 1999-03-25. PMID:9990010. |
dissecting fas signaling with an altered-specificity death-domain mutant: requirement of fadd binding for apoptosis but not jun n-terminal kinase activation. |
1999-03-25 |
2023-08-12 |
Not clear |
| H Y Chang, X Yang, D Baltimor. Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 4. 1999-03-25. PMID:9990010. |
these results suggest that fadd and daxx activate two independent pathways downstream of fas and confirm the essential role of fadd binding in apoptosis induction. |
1999-03-25 |
2023-08-12 |
Not clear |
| H Chan, D P Bartos, L B Owen-Schau. Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment. Molecular and cellular biology. vol 19. issue 3. 1999-03-25. PMID:10022897. |
lymphocyte activation results in the upregulation of fas expression and the acquisition of sensitivity to fasl-mediated apoptosis. |
1999-03-25 |
2023-08-12 |
human |
| T Okazaki, T Kondo, T Kitano, M Tashim. Diversity and complexity of ceramide signalling in apoptosis. Cellular signalling. vol 10. issue 10. 1999-03-23. PMID:9884019. |
diverse kinds of stresses (ultraviolet, irradiation, heat shock and hypoxia) and biological factors (tnf-alpha, ifn-gamma and fas antibody) require ceramide generation to execute apoptosis. |
1999-03-23 |
2023-08-12 |
Not clear |
| G Mantovani, A Macciò, E Massa, P Lai, G Manca, C Mudu, R Versace, G Puscedd. Relationships betxween Fas expression, activation molecule CD25, and functional activity of tumor-associated lymphomonocytes from neoplastic effusions. Oncology reports. vol 6. issue 1. 1999-03-22. PMID:9864435. |
fas ligand (fasl), a cell surface molecule belonging to the tumor necrosis factor family, binds to its receptor fas, thus inducing apoptosis of fas bearing cells. |
1999-03-22 |
2023-08-12 |
human |
| K Mori, K Komamura, N Ohta, K Yoneda, K Miyatake, Y Katayam. [Relationship between apoptosis-related markers and cardiomyopathy]. Rinsho byori. The Japanese journal of clinical pathology. vol 46. issue 12. 1999-03-22. PMID:9916510. |
interactions between soluble fas, tumor necrosis factor-alpha (tnf-alpha) and fas ligand have been reported to play a pivotal part in signal transduction of apoptosis. |
1999-03-22 |
2023-08-12 |
Not clear |
| H Tomizuka, K Hatake, M Ikeda, Y Gunji, K Ikeda, T Takizawa, T Saito, Y Hoshino, T Ohtsuki, H Takahashi, S Yonehara, Y Miur. CD95 predicts responsiveness to tretinoin in acute promyelocytic leukemia. International journal of molecular medicine. vol 1. issue 1. 1999-03-16. PMID:9852221. |
expression of cd95 (fas antigen), which plays a major role in apoptosis, was determined by fluorescence activated cell sorter (facs) analysis. |
1999-03-16 |
2023-08-12 |
Not clear |
| H Miyoshi, G J Gore. Apoptosis and the liver: relevance for the hepato-biliary-pancreatic surgeon. Journal of hepato-biliary-pancreatic surgery. vol 5. issue 4. 1999-03-16. PMID:9931390. |
in this article, we review current scientific and clinical concepts of apoptosis, including death factors such as fas ligand and tumor necrosis factor, apoptotic signal transduction mechanisms, and the role of intracellular proteinases called caspases. |
1999-03-16 |
2023-08-12 |
Not clear |
| R Tóth, E Szegezdi, G Molnár, J M Lord, L Fésüs, Z Szond. Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively. European journal of immunology. vol 29. issue 2. 1999-03-16. PMID:10064053. |
regulation of cell surface expression of fas (cd95) ligand and susceptibility to fas (cd95)-mediated apoptosis in activation-induced t cell death involves calcineurin and protein kinase c, respectively. |
1999-03-16 |
2023-08-12 |
Not clear |
| R Tóth, E Szegezdi, G Molnár, J M Lord, L Fésüs, Z Szond. Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively. European journal of immunology. vol 29. issue 2. 1999-03-16. PMID:10064053. |
these cells express fas and fasl mrna, cell surface fas and intracellular fasl, but do not enter apoptosis upon fas ligation prior to tcr stimulation. |
1999-03-16 |
2023-08-12 |
Not clear |
| R Tóth, E Szegezdi, G Molnár, J M Lord, L Fésüs, Z Szond. Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively. European journal of immunology. vol 29. issue 2. 1999-03-16. PMID:10064053. |
addition of phorbol dibutyrate (pbu2) alone was sufficient to induce susceptibility to fas ligation induced apoptosis, while addition of both pbu2 and calcium ionophore a23187 were required to induce fasl cell surface expression. |
1999-03-16 |
2023-08-12 |
Not clear |
| R Tóth, E Szegezdi, G Molnár, J M Lord, L Fésüs, Z Szond. Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively. European journal of immunology. vol 29. issue 2. 1999-03-16. PMID:10064053. |
addition of cyclosporin a completely inhibited tcr-mediated death and fasl cell surface up-regulation, but had no effect on apoptosis induced directly by fas ligation following tcr stimulation. |
1999-03-16 |
2023-08-12 |
Not clear |
| R Tóth, E Szegezdi, G Molnár, J M Lord, L Fésüs, Z Szond. Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively. European journal of immunology. vol 29. issue 2. 1999-03-16. PMID:10064053. |
our data suggest that in activation-induced t cell apoptosis pkc is involved in pathways that mediate the acquisition of fas susceptibility, while calcineurin is required for cell surface expression of the preformed fasl. |
1999-03-16 |
2023-08-12 |
Not clear |