| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Wu, Qizi Yin, Yi Wang, Rong Wang, Wenjing Gong, Yihang Chen, Mingming Zhang, Yehao Liu, Yanli J. Integrated transcriptome and metabolomic analyses uncover the mechanism of cadmium-caused mouse spermatogonia apoptosis via inducing endoplasmic reticulum stress. Reproductive toxicology (Elmsford, N.Y.). 2024-07-22. PMID:39038763. |
cadmium (cd) is a well-recognized male reproductive toxicant that can cause testicular germ cell apoptosis. |
2024-07-22 |
2024-07-25 |
mouse |
| Qian Zhang, Shuting Li, Jing Fang, Yue Hao, Junge Lu, Lu Zhang, Minmin Zhang, Li Zhang, Yihe Wang, Yu Zhang, Hongying Du, Yuan Gao, Zuosen Yang, Wei Sun, Lingjun Yan, Guowei Pa. The combined effects of polystyrene of different sizes and cadmium in mouse kidney tissues. Ecotoxicology and environmental safety. vol 281. 2024-06-29. PMID:38944012. |
kidney damage was evaluated in male mice gavaged with ps (diameter, 100 nm and/or 1 μm) and cd for 25 days.the results showed that ps at 100 nm caused more severe oxidative damage and cell apoptosis than ps at 1 μm. |
2024-06-29 |
2024-07-02 |
mouse |
| Rastee H Saeed, Zirak Faqe Ahmed Abdulrahman, Dara K Mohamma. Exploring the interplay between microRNA expression and DNA mutation analysis in AML patients. Saudi journal of biological sciences. vol 31. issue 7. 2024-06-04. PMID:38831894. |
mutations in aml can alter mirna profiles, which can affect the expression of cd markers and contribute to disease progression by influencing cellular processes such as differentiation, proliferation, and apoptosis. |
2024-06-04 |
2024-06-06 |
Not clear |
| Min Zhang, Xue Song, Shengbao Liu, Nuo Zhang, Ming Yang, Pengcheng Gao, Zhijun Geng, Lugen Zuo, Xiaofeng Zhang, Lian Wang, Yueyue Wang, Jing Li, Jianguo H. Magnolin inhibits intestinal epithelial cell apoptosis alleviating Crohn's disease-like colitis by suppressing the PI3K/AKT signalling pathway. International immunopharmacology. vol 134. 2024-05-11. PMID:38733829. |
previous reports have shown that preventing excessive intestinal epithelial cell (iec) apoptosis is a crucial approach for protecting the intestinal barrier in patients with crohn's disease (cd). |
2024-05-11 |
2024-05-27 |
Not clear |
| Kong-Wen Ouyang, Tian-Tian Wang, Hua Wang, Ye-Xin Luo, Yi-Fan Hu, Xin-Mei Zheng, Qing Ling, Kai-Wen Wang, Yong-Wei Xiong, Jin Zhang, Wei Chang, Yu-Feng Zhang, Zhi Yuan, Hao Li, Lan Gao, De-Xiang Xu, Hua-Long Zhu, Lan Yang, Hua Wan. m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure. The Science of the total environment. vol 931. 2024-05-09. PMID:38703850. |
it is well-known that environmental cd causes testicular damage by inducing classic types of cell death such as cell apoptosis and necrosis. |
2024-05-09 |
2024-05-27 |
mouse |
| Mohamed Ali Hussein, Abishek Kamalakkannan, Kamyab Valinezhad, Jhishnuraj Kannan, Nikhila Paleati, Rama Saad, André Kajdacsy-Balla, Gnanasekar Munirathina. The dynamic face of cadmium-induced Carcinogenesis: Mechanisms, emerging trends, and future directions. Current research in toxicology. vol 6. 2024-05-06. PMID:38706786. |
moreover, cd mediates apoptosis evasion, autophagy activation, and survival mechanisms. |
2024-05-06 |
2024-05-08 |
Not clear |
| Jiamei Zhu, Xueyan Dai, Yan Wang, Ting Cui, Bingyan Huang, Dianyun Wang, Wenjing Pu, Caiying Zhan. Molybdenum and cadmium co-induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anas platyrhyncha) testes. Poultry science. vol 103. issue 5. 2024-03-27. PMID:38537407. |
the characteristic ultrastructural changes related to apoptosis and ferroptosis were observed in mo or cd or both groups. |
2024-03-27 |
2024-03-30 |
Not clear |
| Jiamei Zhu, Xueyan Dai, Yan Wang, Ting Cui, Bingyan Huang, Dianyun Wang, Wenjing Pu, Caiying Zhan. Molybdenum and cadmium co-induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anas platyrhyncha) testes. Poultry science. vol 103. issue 5. 2024-03-27. PMID:38537407. |
besides, mo or cd or both repressed nuclear factor erythroid 2-related factor 2 (nrf2) pathway via decreasing nrf2, heme oxygenase-1 (ho-1), nad(p)h quinone oxidoreductase 1 (nqo1), glutamate-cysteine ligase catalytic subunit (gclc) and glutamate-cysteine ligase modifier subunit (gclm) mrna expression of and nrf2 protein expression, then stimulated apoptosis by elevating bcl-2 antagonist/killer-1 (bak-1), bcl-2-associated x-protein (bax), cytochrome complex (cyt-c), caspase-3 mrna expression, cleaved-caspase-3 protein expression and apoptosis rate, as well as reducing b-cell lymphoma-2 (bcl-2) mrna expression and ratio of bcl-2 to bax, and triggered ferroptosis by upregulating acyl-coa synthetase long chain family member 4 (acsl4), transferrin receptor (tfr1) and prostaglandin-endoperoxide synthase 2 (ptgs2) expression levels, and downregulating ferritin heavy chain 1 (fth1), ferritin light chain 1 (ftl1), ferroportin 1 (fpn1), solute carrier family 7 member 11 (scl7a11) and glutathione peroxidase 4 (gpx4) expression levels. |
2024-03-27 |
2024-03-30 |
Not clear |
| Jiamei Zhu, Xueyan Dai, Yan Wang, Ting Cui, Bingyan Huang, Dianyun Wang, Wenjing Pu, Caiying Zhan. Molybdenum and cadmium co-induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anas platyrhyncha) testes. Poultry science. vol 103. issue 5. 2024-03-27. PMID:38537407. |
altogether, the results announced that mo or cd or both evoked apoptosis and ferroptosis by inhibiting nrf2 pathway in the testis of ducks, and co-exposure to mo and cd exacerbated these variations. |
2024-03-27 |
2024-03-30 |
Not clear |
| Zikun Zhang, Qi Wang, Xiaoge Gao, Xu Tang, Huan Xu, Wenqiang Wang, Xin Le. Reproductive toxicity of cadmium stress in male animals. Toxicology. 2024-03-24. PMID:38522818. |
therefore, this paper reviewed the toxic effects of cd on germ cells, spermatogonia somatic cells and hypothalamic-pituitary-gonadal axis (hpg axis) of male animals and its toxic action mechanisms of oxidative stress, apoptosis and autophagy from the perspectives of cytology, genetics and neuroendocrinology. |
2024-03-24 |
2024-03-27 |
Not clear |
| Fusen Yue, Jinsheng Xu, Linyi Meng, Qi Wang, Mingtao Tan, Aoying Zhang, Shanchun Yan, Dun Jian. A new insight into Cd exposure-induced hemocyte reduction in Lymantria dispar larvae: Involvement of the ROS-ATF6-ER stress-apoptosis pathway. Journal of hazardous materials. vol 469. 2024-03-20. PMID:38508113. |
the results showed that the number of larval hemocytes was significantly decreased under cd exposure, accompanied by a significant increase in the apoptosis rate and the expression of caspase-3. |
2024-03-20 |
2024-03-23 |
Not clear |
| Qingqing Li, Jing Li, Lixia Yin, Ju Huang, Xinyue Liu, Jinran Shi, Zhijun Geng, Xue Song, Lian Wang, Yueyue Wang, Xiaofeng Zhang, Lugen Zuo, Jianguo H. Sophoricoside improved Crohn's disease-like colitis by inhibiting intestinal epithelial cell apoptosis through PI3K/AKT signaling. International immunopharmacology. vol 131. 2024-03-17. PMID:38493691. |
increased apoptosis of intestinal epithelial cells (iecs) is a significant cause of intestinal barrier dysfunction in crohn's disease (cd). |
2024-03-17 |
2024-03-20 |
mouse |
| Danna Xie, Jun Yan, Honglong Zhang, Haijun Zhang, Guole Nie, Xingwang Zhu, Xun L. Cadmium exacerbates liver injury by remodeling ceramide metabolism: Multiomics and laboratory evidence. The Science of the total environment. 2024-03-03. PMID:38432385. |
in summary, cd increased ceramide levels by remodeling ceramide synthesis and catabolism, thereby promoting hepatocyte apoptosis and oxidative stress and ultimately aggravating liver injury. |
2024-03-03 |
2024-03-06 |
rat |
| Na Chen, Xiaoyan Wan, Mei Wang, Yamin Li, Xiaofei Wang, Ling Zeng, Jinzhao Zhou, Yanwei Zhang, Shun Cheng, Yi She. Cross-talk between Vimentin and autophagy regulates blood-testis barrier disruption induced by cadmium. Environmental pollution (Barking, Essex : 1987). 2024-02-24. PMID:38401636. |
we observed that cd can induce btb disruption, leading to apoptosis of testicular cells. |
2024-02-24 |
2024-02-27 |
Not clear |
| Na Chen, Xiaoyan Wan, Shun Cheng, Guiju Tang, Dan Xia, Yanling Xu, Yi She. Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis. Ecotoxicology and environmental safety. vol 273. 2024-02-17. PMID:38367604. |
we found that cd treatment caused a significant increase of apoptosis in scs cells, accompanied by a marked increase in the production of ros. |
2024-02-17 |
2024-02-20 |
Not clear |
| Na Chen, Xiaoyan Wan, Shun Cheng, Guiju Tang, Dan Xia, Yanling Xu, Yi She. Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis. Ecotoxicology and environmental safety. vol 273. 2024-02-17. PMID:38367604. |
together, this study provides insight into the negative effects of cd, which interferes with autophagic flux and induces the apoptosis of scs. |
2024-02-17 |
2024-02-20 |
Not clear |
| Zhonggui Gong, Wenjing Liu, Ruilong Song, Wenxuan Dong, Kanglei Zhang, Jiahui Li, Hui Zou, Jiaqiao Zhu, Yonggang Ma, Gang Liu, Zongping Li. Nuclear factor-kappaB mediates the survival of rat kidney cells after cadmium exposure via promoting autophagy and inhibiting apoptosis. Ecotoxicology and environmental safety. vol 249. 2024-02-07. PMID:38321684. |
in conclusion, cd exposure promotes the activation of nf-κb, and activated nf-κb mediates the survival of nrk-52e cells after cd exposure via promoting autophagy and inhibiting apoptosis. |
2024-02-07 |
2024-02-09 |
rat |
| Zili Lv, Jun Hu, Mingquan Huang, Guangrui Pan, Guofeng Xu, Meng Yan. Molecular mechanisms of cadmium-induced cytotoxicity in human ovarian granulosa cells identified using integrated omics. Ecotoxicology and environmental safety. vol 272. 2024-01-30. PMID:38290317. |
cd exposure was found to not only induce the apoptosis of the kgn cells but also further reduced mitochondrial function by decreasing mitochondrial membrane potential, atp production, and respiratory chain complex activity as well as increasing mitochondrial reactive oxygen species (ros) production. |
2024-01-30 |
2024-02-02 |
human |
| Inés Moret-Tatay, Pilar Nos, Marisa Iborra, Francisco Rausell, Belén Beltrá. Catalase inhibition can modulate the ability of peripheral blood T cells to undergo apoptosis in Crohn's disease. Clinical and experimental immunology. 2024-01-22. PMID:38247555. |
crohn's disease (cd) is a chronic relapsing inflammatory disorder in which defective apoptosis of mucosal t cells is postulated to produce sustained inflammation and reactive oxygen species accumulation. |
2024-01-22 |
2024-01-24 |
Not clear |
| Inés Moret-Tatay, Pilar Nos, Marisa Iborra, Francisco Rausell, Belén Beltrá. Catalase inhibition can modulate the ability of peripheral blood T cells to undergo apoptosis in Crohn's disease. Clinical and experimental immunology. 2024-01-22. PMID:38247555. |
whether cd t cells are intrinsically resistant to apoptosis or whether this resistance is acquired at the intestinal site needs to be clarified, as the cellular mechanisms modulate the impaired apoptosis in these cells. |
2024-01-22 |
2024-01-24 |
Not clear |