| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Abmayr, R W Crawford, J S Chamberlai. Characterization of ARC, apoptosis repressor interacting with CARD, in normal and dystrophin-deficient skeletal muscle. Human molecular genetics. vol 13. issue 2. 2004-08-18. PMID:14645204. |
characterization of arc, apoptosis repressor interacting with card, in normal and dystrophin-deficient skeletal muscle. |
2004-08-18 |
2023-08-12 |
mouse |
| S Abmayr, R W Crawford, J S Chamberlai. Characterization of ARC, apoptosis repressor interacting with CARD, in normal and dystrophin-deficient skeletal muscle. Human molecular genetics. vol 13. issue 2. 2004-08-18. PMID:14645204. |
recent studies have identified arc (apoptosis repressor with caspase recruitment domain) as an abundant protein in human muscle that can inhibit both hypoxia and caspase-8-induced apoptosis as well as protect cells from oxidative stress. |
2004-08-18 |
2023-08-12 |
mouse |
| Asa B Gustafsson, Joseph G Tsai, Susan E Logue, Michael T Crow, Roberta A Gottlie. Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation. The Journal of biological chemistry. vol 279. issue 20. 2004-07-21. PMID:15004034. |
the apoptosis repressor with caspase recruitment domain (arc) is a protein that is highly expressed in heart and skeletal muscle and has been demonstrated to protect the heart against i/r injury (gustafsson, a. |
2004-07-21 |
2023-08-12 |
crow |
| Deborah Lyn, Shaojia Bao, Nicole A Bennett, Xiaowei Liu, Nerimiah L Emmet. Ischemia elicits a coordinated expression of pro-survival proteins in mouse myocardium. TheScientificWorldJournal. vol 2. 2004-02-20. PMID:12805954. |
alterations of pro-survival proteins such as the inhibitor of apoptosis protein on chromosome x (xiap) and the apoptotic repressor protein (arc) have not been evaluated in a murine model of cardiac ischemia. |
2004-02-20 |
2023-08-12 |
mouse |
| Motoya Sato, Hiroshi Ohguro, Ikuyo Ohguro, Kazuhisa Mamiya, Yoshiko Takano, Hitoshi Yamazaki, Tomomi Metoki, Yasuhiro Miyagawa, Fotoshi Ishikawa, Mitsuru Nakazaw. Study of pharmacological effects of nilvadipine on RCS rat retinal degeneration by microarray analysis. Biochemical and biophysical research communications. vol 306. issue 4. 2003-08-11. PMID:12821116. |
remarkably, neurotrophic factors, fgf-2 and arc, known to suppress the apoptosis in the central nervous system, were up-regulated. |
2003-08-11 |
2023-08-12 |
rat |
| Daryoush Ekhterae, Oleksandr Platoshyn, Shen Zhang, Carmelle V Remillard, Jason X-J Yua. Apoptosis repressor with caspase domain inhibits cardiomyocyte apoptosis by reducing K+ currents. American journal of physiology. Cell physiology. vol 284. issue 6. 2003-07-07. PMID:12734105. |
we examined whether apoptotic repressor with caspase recruitment domain (arc), an antiapoptotic protein, inhibits cardiomyocyte apoptosis by reducing k(+) efflux through voltage-gated k(+) (kv) channels. |
2003-07-07 |
2023-08-12 |
Not clear |
| Daryoush Ekhterae, Oleksandr Platoshyn, Shen Zhang, Carmelle V Remillard, Jason X-J Yua. Apoptosis repressor with caspase domain inhibits cardiomyocyte apoptosis by reducing K+ currents. American journal of physiology. Cell physiology. vol 284. issue 6. 2003-07-07. PMID:12734105. |
overexpression of arc in heart-derived h9c2 cells significantly decreased i(k(v)), whereas treatment with staurosporine, a potent apoptosis inducer, enhanced i(k(v)) in wild-type cells. |
2003-07-07 |
2023-08-12 |
Not clear |
| Daryoush Ekhterae, Oleksandr Platoshyn, Shen Zhang, Carmelle V Remillard, Jason X-J Yua. Apoptosis repressor with caspase domain inhibits cardiomyocyte apoptosis by reducing K+ currents. American journal of physiology. Cell physiology. vol 284. issue 6. 2003-07-07. PMID:12734105. |
the staurosporine-induced increase in i(k(v)) was significantly suppressed and the staurosporine-mediated apoptosis was markedly inhibited in cells overexpressing arc compared with cells transfected with the control neomycin vector. |
2003-07-07 |
2023-08-12 |
Not clear |
| Yeon-Mi Hong, Dong-Gyu Jo, Joo-Yong Lee, Jae-Woong Chang, Jung-Hyun Nam, Jee Yeon Noh, Jae-Young Koh, Yong-Keun Jun. Down-regulation of ARC contributes to vulnerability of hippocampal neurons to ischemia/hypoxia. FEBS letters. vol 543. issue 1-3. 2003-06-25. PMID:12753927. |
arc is a caspase recruitment domain-containing molecule that plays an important role in the regulation of apoptosis. |
2003-06-25 |
2023-08-12 |
Not clear |
| Rajani R J Shelke, Christiaan Leeuwenburg. Lifelong caloric restriction increases expression of apoptosis repressor with a caspase recruitment domain (ARC) in the brain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 3. 2003-04-01. PMID:12514107. |
lifelong caloric restriction increases expression of apoptosis repressor with a caspase recruitment domain (arc) in the brain. |
2003-04-01 |
2023-08-12 |
rat |
| Rajani R J Shelke, Christiaan Leeuwenburg. Lifelong caloric restriction increases expression of apoptosis repressor with a caspase recruitment domain (ARC) in the brain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 3. 2003-04-01. PMID:12514107. |
we determined levels of arc (apoptosis repressor with a caspase recruitment domain), which inhibits caspase-2 activity and also attenuates cytochrome c release from the mitochondria. |
2003-04-01 |
2023-08-12 |
rat |
| T Gulesserian, E Engidawork, B C Yoo, N Cairns, G Lube. Alteration of caspases and other apoptosis regulatory proteins in Down syndrome. Journal of neural transmission. Supplementum. issue 61. 2002-06-10. PMID:11771741. |
in contrast, cytochrome c, apaf-1 (apoptosis protease activating factor-1), procaspase-9 and arc (apoptosis repressor with caspase recruitment domain) were unchanged. |
2002-06-10 |
2023-08-12 |
human |
| T A Dowds, E L Sabba. Endogenous and exogenous ARC in serum withdrawal mediated PC12 cell apoptosis: a new pro-apoptotic role for ARC. Cell death and differentiation. vol 8. issue 6. 2001-11-01. PMID:11536015. |
endogenous and exogenous arc in serum withdrawal mediated pc12 cell apoptosis: a new pro-apoptotic role for arc. |
2001-11-01 |
2023-08-12 |
Not clear |
| T A Dowds, E L Sabba. Endogenous and exogenous ARC in serum withdrawal mediated PC12 cell apoptosis: a new pro-apoptotic role for ARC. Cell death and differentiation. vol 8. issue 6. 2001-11-01. PMID:11536015. |
the role of arc (apoptosis repressor with caspase recruitment domain) in pc12 cell serum withdrawal driven apoptosis was studied. |
2001-11-01 |
2023-08-12 |
Not clear |
| T A Dowds, E L Sabba. Endogenous and exogenous ARC in serum withdrawal mediated PC12 cell apoptosis: a new pro-apoptotic role for ARC. Cell death and differentiation. vol 8. issue 6. 2001-11-01. PMID:11536015. |
therefore, arc functions in a pro-apoptotic manner in pc12 cell serum withdrawal induced apoptosis. |
2001-11-01 |
2023-08-12 |
Not clear |
| M Neuss, R Monticone, M S Lundberg, A T Chesley, E Fleck, M T Cro. The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function. The Journal of biological chemistry. vol 276. issue 36. 2001-10-11. PMID:11438535. |
the apoptotic regulatory protein arc (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function. |
2001-10-11 |
2023-08-12 |
human |
| M Neuss, R Monticone, M S Lundberg, A T Chesley, E Fleck, M T Cro. The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function. The Journal of biological chemistry. vol 276. issue 36. 2001-10-11. PMID:11438535. |
because arc also blocks caspase-independent events associated with apoptosis, such as hypoxia-induced cytochrome c release, we examined its role in cell death triggered by exposure to hydrogen peroxide (h(2)o(2)) in the myogenic cell line, h9c2. |
2001-10-11 |
2023-08-12 |
human |
| M Neuss, R Monticone, M S Lundberg, A T Chesley, E Fleck, M T Cro. The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function. The Journal of biological chemistry. vol 276. issue 36. 2001-10-11. PMID:11438535. |
these results demonstrate that, in addition to its ability to block caspase-dependent and -independent events in apoptosis, arc also prevents necrosis-like cell death via the preservation of mitochondrial function. |
2001-10-11 |
2023-08-12 |
human |
| E Engidawork, T Gulesserian, B C Yoo, N Cairns, G Lube. Alteration of caspases and apoptosis-related proteins in brains of patients with Alzheimer's disease. Biochemical and biophysical research communications. vol 281. issue 1. 2001-04-05. PMID:11178964. |
the protein levels of caspase-3, -8, and -9, dff45 (dna fragmentation factor 45), and flip (fas associated death domain (fadd)-like interleukin-1beta-converting enzyme inhibitory proteins) were decreased, whereas those of arc (apoptosis repressor with caspase recruitment domain) and rick (receptor interacting protein (rip)-like interacting clarp kinase) increased in ad. |
2001-04-05 |
2023-08-12 |
human |
| D Ekhterae, Z Lin, M S Lundberg, M T Crow, F C Brosius, G Núñe. ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells. Circulation research. vol 85. issue 12. 1999-12-21. PMID:10590251. |
arc inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived h9c2 cells. |
1999-12-21 |
2023-08-12 |
rat |